PT771794E - Compostos heterociclicos contendo oxigenio - Google Patents
Compostos heterociclicos contendo oxigenioInfo
- Publication number
- PT771794E PT771794E PT96915194T PT96915194T PT771794E PT 771794 E PT771794 E PT 771794E PT 96915194 T PT96915194 T PT 96915194T PT 96915194 T PT96915194 T PT 96915194T PT 771794 E PT771794 E PT 771794E
- Authority
- PT
- Portugal
- Prior art keywords
- bond
- cyano
- combined
- compounds containing
- containing oxygen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12153795 | 1995-05-19 | ||
| JP25865195 | 1995-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT771794E true PT771794E (pt) | 2006-09-29 |
Family
ID=26458881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96915194T PT771794E (pt) | 1995-05-19 | 1996-05-20 | Compostos heterociclicos contendo oxigenio |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0771794B1 (pt) |
| JP (1) | JP4172817B2 (pt) |
| KR (1) | KR100445356B1 (pt) |
| CN (1) | CN1163493C (pt) |
| AT (1) | ATE325110T1 (pt) |
| AU (1) | AU705690B2 (pt) |
| CA (1) | CA2195755A1 (pt) |
| DE (1) | DE69636086T2 (pt) |
| DK (1) | DK0771794T3 (pt) |
| ES (1) | ES2258775T3 (pt) |
| HK (1) | HK1000785A1 (pt) |
| NO (1) | NO317631B1 (pt) |
| PT (1) | PT771794E (pt) |
| WO (1) | WO1996036624A1 (pt) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59610077D1 (de) * | 1995-05-18 | 2003-02-27 | Altana Pharma Ag | Phenyldihydrobenzofurane |
| CA2221351A1 (en) * | 1995-05-18 | 1996-11-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Cyclohexyl dihydrobenzofuranes |
| DE69620458T2 (de) * | 1995-12-05 | 2002-10-02 | Darwin Discovery Ltd | Benzofuran-carboxamide und -sulfonamide |
| BR9709113A (pt) * | 1996-05-20 | 1999-08-03 | Darwin Discovery Ltd | Benzofurano carboxamidas e seu uso terapêutico |
| DE69717827T2 (de) * | 1996-08-19 | 2003-09-04 | Altana Pharma Ag | Benzofuran-4-carboxamide |
| EP0943613A4 (en) * | 1996-11-19 | 2002-07-10 | Kyowa Hakko Kogyo Kk | HETEROCYCLIC COMPOUNDS CONTAINING OXYGEN |
| DE69813605T2 (de) * | 1997-10-01 | 2004-02-12 | Kyowa Hakko Kogyo Co., Ltd. | Benzofuranderivate |
| WO1999040085A1 (en) * | 1998-02-09 | 1999-08-12 | Darwin Discovery Limited | Benzofuran-4-carboxamides and their therapeutic use |
| PT1095040E (pt) * | 1998-07-06 | 2004-08-31 | Altana Pharma Ag | Novos benzoxazoles com actividade inibidora da pde |
| EP1110961B1 (en) | 1998-09-03 | 2004-07-14 | Kyowa Hakko Kogyo Co., Ltd. | Oxygenic heterocyclic compounds |
| ATE387498T1 (de) * | 1998-12-30 | 2008-03-15 | Oligos Etc Inc | Therapeutische pde4d phosphodiesterase inhibitoren |
| WO2001007031A1 (fr) * | 1999-07-26 | 2001-02-01 | Shionogi & Co., Ltd. | Derives de benzene, compositions immunostimulantes ou agents de retablissement de la pharmacosensibilite les contenant |
| WO2003000697A1 (fr) * | 2001-06-22 | 2003-01-03 | Takeda Chemical Industries, Ltd. | Derive de furo-isoquinoline, procede de production de ce compose et utilisation de ce compose |
| DE10205274A1 (de) * | 2002-02-08 | 2003-08-21 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen |
| DE10216427A1 (de) * | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Arzneimittelkompositionen enthaltend heterocyclische Verbindungen und ein neues Anticholinergikum |
| JPWO2004005276A1 (ja) * | 2002-07-03 | 2005-11-04 | 協和醗酵工業株式会社 | １，３−ベンゾジオキソール−２−スピロシクロアルカン誘導体の製造法 |
| US20060205749A1 (en) * | 2003-03-13 | 2006-09-14 | Yuzuru Abe | Remedy and/or preventive for lung diseases |
| WO2004082683A1 (ja) * | 2003-03-17 | 2004-09-30 | Kyowa Hakko Kogyo Co., Ltd. | 慢性皮膚疾患の治療および／または予防剤 |
| TW200503706A (en) * | 2003-03-31 | 2005-02-01 | Kyowa Hakko Kogyo Kk | Treating and/or preventing agent for pulmonary diseases |
| WO2004087150A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co. Ltd. | 医薬組成物 |
| TW200420554A (en) * | 2003-03-31 | 2004-10-16 | Kyowa Hakko Kogyo Kk | A intra-airway administrating preparation |
| WO2004087146A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | 微粒子混合物の製造方法 |
| CA2520577A1 (en) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | Pharmaceutical composition |
| JPWO2004087151A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 医薬組成物 |
| WO2004112791A1 (ja) * | 2003-06-23 | 2004-12-29 | Kyowa Hakko Kogyo Co., Ltd. | 肺疾患の治療および／または予防剤 |
| EP1504756A1 (en) * | 2003-08-06 | 2005-02-09 | Kyowa Hakko Kogyo Co., Ltd | Medicament compositions comprising a heterocyclic compound and an anticholinergic |
| CA2584169A1 (en) * | 2004-10-13 | 2006-04-20 | Kyowa Hakko Kogyo Co., Ltd. | Remedies/preventives for chronic skin disease |
| JPWO2006041120A1 (ja) * | 2004-10-13 | 2008-05-15 | 協和醗酵工業株式会社 | 医薬組成物 |
| WO2006123726A1 (ja) * | 2005-05-18 | 2006-11-23 | Kyowa Hakko Kogyo Co., Ltd. | 医薬組成物 |
| US20100056791A1 (en) * | 2006-09-01 | 2010-03-04 | Yasushi Kohno | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
| CA2661992A1 (en) | 2006-09-06 | 2008-03-13 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine derivative and phosphodiesterase (pde) inhibitor containing the same as active ingredient |
| MX2009006593A (es) * | 2006-12-22 | 2009-07-02 | Leo Pharma As | Acetofenonas sustituidas utiles como inhibidores de fosfodiesterasa 4. |
| MX2009009238A (es) | 2007-02-28 | 2009-09-08 | Leo Pharma As | Nuevos inhibidores de fosfodiesterasa. |
| WO2008125111A1 (en) | 2007-04-16 | 2008-10-23 | Leo Pharma A/S | Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases |
| MX2011006428A (es) | 2008-12-19 | 2011-07-28 | Leo Pharma As | Triazolopiridinas como inhibidores de fosfodiesterasa para tratamiento de enfermedades dermicas. |
| US8980905B2 (en) | 2010-06-24 | 2015-03-17 | Leo Pharma A/S | Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors |
| JP6138150B2 (ja) | 2011-12-21 | 2017-05-31 | レオ ファーマ アクティーゼルスカブ | ［１，２，４］トリアゾロピリジンおよびホスホジエステラーゼ阻害剤としてのその使用 |
| MX2016016378A (es) * | 2014-06-23 | 2017-10-16 | Leo Pharma As | Metodos para la preparacion de compuestos heterociclicos de 1,3-benzodioxol. |
| CN106588841B (zh) * | 2015-10-19 | 2019-01-25 | 富乐马鸿凯（大连）医药有限公司 | 合成2,3-二氢-1-苯并呋喃-4-甲醛的方法 |
| CN106588900A (zh) * | 2015-10-20 | 2017-04-26 | 北京康辰医药科技有限公司 | 一种苯并双环化合物或其药学上可接受的盐、药物组合物及其应用 |
| CN106905336B (zh) * | 2017-01-22 | 2019-04-09 | 浙江工业大学 | 一种手性吡唑螺呋喃类化合物的不对称合成方法 |
| CN107325067B (zh) * | 2017-05-03 | 2020-05-12 | 广州中医药大学 | 磷酸二酯酶4抑制剂桑辛素m衍生物及其用途 |
| CN109721580B (zh) * | 2017-10-27 | 2022-11-04 | 中国医学科学院药物研究所 | 3-苯基-7,8-脱氢葡萄藤戊素衍生物、其制法和药物组合物与用途 |
| CN109721579B (zh) * | 2017-10-27 | 2022-11-04 | 中国医学科学院药物研究所 | 7,8-脱氢葡萄藤戊素衍生物、其制法和药物组合物与用途 |
| CN114478413B (zh) * | 2022-01-14 | 2023-06-23 | 北京富盛嘉华医药科技有限公司 | 2-(2′-羟基-3′-甲代烯丙基-5′-甲基苯基)苯并三氮唑的制备方法及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
| CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
| JPS62234083A (ja) * | 1986-02-28 | 1987-10-14 | アーバモント インク ディビーエイ アドリヤ ラボラトリーズ | 鎮吐薬または精神病治療薬として有用なカルボキサミド類 |
| JPH01207267A (ja) * | 1987-03-05 | 1989-08-21 | Yamanouchi Pharmaceut Co Ltd | ピリジン誘導体及び該化合物を含有する肝疾患治療剤 |
| ZA886585B (en) * | 1987-09-08 | 1990-05-30 | Lilly Co Eli | Specific 5-ht,antagonists |
| US5366986A (en) * | 1988-04-15 | 1994-11-22 | T Cell Sciences, Inc. | Compounds which inhibit complement and/or suppress immune activity |
| AU670949B2 (en) * | 1992-06-15 | 1996-08-08 | Celltech Limited | Trisubstituted phenyl derivatives as selective phosphodiesterase IV inhibitors |
| KR100381584B1 (ko) * | 1994-07-22 | 2003-08-21 | 알타나 파마 아게 | 디히드로벤조푸란 |
| DE59610077D1 (de) * | 1995-05-18 | 2003-02-27 | Altana Pharma Ag | Phenyldihydrobenzofurane |
-
1996
- 1996-05-20 CN CNB961905298A patent/CN1163493C/zh not_active Expired - Fee Related
- 1996-05-20 WO PCT/JP1996/001327 patent/WO1996036624A1/ja active IP Right Grant
- 1996-05-20 AU AU57029/96A patent/AU705690B2/en not_active Ceased
- 1996-05-20 DE DE69636086T patent/DE69636086T2/de not_active Expired - Fee Related
- 1996-05-20 DK DK96915194T patent/DK0771794T3/da active
- 1996-05-20 JP JP53470896A patent/JP4172817B2/ja not_active Expired - Fee Related
- 1996-05-20 ES ES96915194T patent/ES2258775T3/es not_active Expired - Lifetime
- 1996-05-20 EP EP96915194A patent/EP0771794B1/en not_active Expired - Lifetime
- 1996-05-20 AT AT96915194T patent/ATE325110T1/de not_active IP Right Cessation
- 1996-05-20 PT PT96915194T patent/PT771794E/pt unknown
- 1996-05-20 CA CA002195755A patent/CA2195755A1/en not_active Abandoned
- 1996-05-20 KR KR1019970700326A patent/KR100445356B1/ko not_active IP Right Cessation
-
1997
- 1997-01-14 NO NO19970151A patent/NO317631B1/no unknown
- 1997-11-28 HK HK97102285A patent/HK1000785A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU705690B2 (en) | 1999-05-27 |
| HK1000785A1 (en) | 2006-06-30 |
| WO1996036624A1 (fr) | 1996-11-21 |
| KR100445356B1 (ko) | 2004-11-12 |
| NO317631B1 (no) | 2004-11-29 |
| CA2195755A1 (en) | 1996-11-21 |
| EP0771794A1 (en) | 1997-05-07 |
| EP0771794B1 (en) | 2006-05-03 |
| NO970151L (no) | 1997-03-06 |
| DE69636086D1 (de) | 2006-06-08 |
| ATE325110T1 (de) | 2006-06-15 |
| KR970704724A (ko) | 1997-09-06 |
| JP4172817B2 (ja) | 2008-10-29 |
| CN1154697A (zh) | 1997-07-16 |
| ES2258775T3 (es) | 2006-09-01 |
| EP0771794A4 (en) | 1998-09-02 |
| DK0771794T3 (da) | 2006-09-11 |
| NO970151D0 (no) | 1997-01-14 |
| DE69636086T2 (de) | 2006-11-30 |
| CN1163493C (zh) | 2004-08-25 |
| AU5702996A (en) | 1996-11-29 |
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