ATE263166T1 - Neue benzoxazole mit pde-hemmender wirkung - Google Patents

Neue benzoxazole mit pde-hemmender wirkung

Info

Publication number
ATE263166T1
ATE263166T1 AT99931198T AT99931198T ATE263166T1 AT E263166 T1 ATE263166 T1 AT E263166T1 AT 99931198 T AT99931198 T AT 99931198T AT 99931198 T AT99931198 T AT 99931198T AT E263166 T1 ATE263166 T1 AT E263166T1
Authority
AT
Austria
Prior art keywords
pde
inhibiting effect
benzoxazoles
new
new benzoxazoles
Prior art date
Application number
AT99931198T
Other languages
English (en)
Inventor
Wolf-Ruediger Ulrich
Hermann Amschler
Thomas Baer
Dieter Flockerzi
Beate Schmidt
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Rolf Beume
Hans-Peter Kley
Dietrich Haefner
Thomas Martin
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE263166T1 publication Critical patent/ATE263166T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99931198T 1998-07-06 1999-06-26 Neue benzoxazole mit pde-hemmender wirkung ATE263166T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98112469 1998-07-06
PCT/EP1999/004451 WO2000001695A1 (en) 1998-07-06 1999-06-26 New benzoxazoles with pde-inhibiting activity

Publications (1)

Publication Number Publication Date
ATE263166T1 true ATE263166T1 (de) 2004-04-15

Family

ID=8232222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99931198T ATE263166T1 (de) 1998-07-06 1999-06-26 Neue benzoxazole mit pde-hemmender wirkung

Country Status (14)

Country Link
US (1) US6376485B1 (de)
EP (1) EP1095040B1 (de)
JP (1) JP2002519423A (de)
AT (1) ATE263166T1 (de)
AU (1) AU761647B2 (de)
CA (1) CA2336894A1 (de)
DE (1) DE69916066T2 (de)
DK (1) DK1095040T3 (de)
ES (1) ES2219031T3 (de)
IL (1) IL140468A0 (de)
PT (1) PT1095040E (de)
SI (1) SI1095040T1 (de)
WO (1) WO2000001695A1 (de)
ZA (1) ZA200100088B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス,インコーポレイティド ムスカリン性受容体調節による神経発生
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2068872A1 (de) 2006-09-08 2009-06-17 Braincells, Inc. Kombinationen mit einem 4-acylaminopyridin-derivat
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
JP5529746B2 (ja) * 2007-11-21 2014-06-25 デコード ジェネティクス イーエイチエフ 炎症性疾患、心臓血管疾患及び中枢神経系障害を治療するための置換されたベンゾアゾールpde4阻害剤
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405633A (en) * 1982-03-01 1983-09-20 Usv Pharmaceutical Corporation Method of treatment of asthma
US4490373A (en) * 1983-05-20 1984-12-25 Usv Pharmaceutical Corporation Method of treating asthma
SK45497A3 (en) * 1994-10-12 1997-10-08 Euro Celtique Sa Benzoxazoles, pharmaceutical composition containing them and their use
US6080782A (en) * 1995-05-18 2000-06-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Cyclohexyl dihydrobenzofuranes
AU705690B2 (en) * 1995-05-19 1999-05-27 Kyowa Hakko Kogyo Co. Ltd. Oxygen-containing heterocyclic compounds

Also Published As

Publication number Publication date
ZA200100088B (en) 2002-05-06
PT1095040E (pt) 2004-08-31
DE69916066D1 (de) 2004-05-06
DE69916066T2 (de) 2005-02-24
SI1095040T1 (en) 2004-10-31
AU4778699A (en) 2000-01-24
JP2002519423A (ja) 2002-07-02
AU761647B2 (en) 2003-06-05
ES2219031T3 (es) 2004-11-16
EP1095040B1 (de) 2004-03-31
IL140468A0 (en) 2002-02-10
DK1095040T3 (da) 2004-07-26
CA2336894A1 (en) 2000-01-13
WO2000001695A1 (en) 2000-01-13
EP1095040A1 (de) 2001-05-02
US6376485B1 (en) 2002-04-23

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