DK1095040T3 - Hidtil ukendte benzoxazoler med PDE-inhiberende aktivitet - Google Patents

Hidtil ukendte benzoxazoler med PDE-inhiberende aktivitet

Info

Publication number
DK1095040T3
DK1095040T3 DK99931198T DK99931198T DK1095040T3 DK 1095040 T3 DK1095040 T3 DK 1095040T3 DK 99931198 T DK99931198 T DK 99931198T DK 99931198 T DK99931198 T DK 99931198T DK 1095040 T3 DK1095040 T3 DK 1095040T3
Authority
DK
Denmark
Prior art keywords
inhibitory activity
pde inhibitory
pde
benzoxazoles
novel
Prior art date
Application number
DK99931198T
Other languages
Danish (da)
English (en)
Inventor
Wolf-Ruediger Ulrich
Hermann Amschler
Beate Schmidt
Hildegard Boss
Thomas Martin
Thomas Baer
Dieter Flockerzi
Beate Gutterer
Ulrich Thibaut
Armin Hatzelmann
Rolf Beume
Hans-Peter Kley
Dietrich Haefner
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1095040T3 publication Critical patent/DK1095040T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99931198T 1998-07-06 1999-06-26 Hidtil ukendte benzoxazoler med PDE-inhiberende aktivitet DK1095040T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98112469 1998-07-06

Publications (1)

Publication Number Publication Date
DK1095040T3 true DK1095040T3 (da) 2004-07-26

Family

ID=8232222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99931198T DK1095040T3 (da) 1998-07-06 1999-06-26 Hidtil ukendte benzoxazoler med PDE-inhiberende aktivitet

Country Status (14)

Country Link
US (1) US6376485B1 (de)
EP (1) EP1095040B1 (de)
JP (1) JP2002519423A (de)
AT (1) ATE263166T1 (de)
AU (1) AU761647B2 (de)
CA (1) CA2336894A1 (de)
DE (1) DE69916066T2 (de)
DK (1) DK1095040T3 (de)
ES (1) ES2219031T3 (de)
IL (1) IL140468A0 (de)
PT (1) PT1095040E (de)
SI (1) SI1095040T1 (de)
WO (1) WO2000001695A1 (de)
ZA (1) ZA200100088B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83620C2 (ru) 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
EP2258357A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
EP2275095A3 (de) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese durch modulation des Muscarinrezeptors
EP2377530A3 (de) 2005-10-21 2012-06-20 Braincells, Inc. Modulation von Neurogenese durch PDE-Hemmung
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
CA2722591A1 (en) * 2007-11-21 2009-05-28 Decode Genetics Ehf. Substituted benzoazole pde4 inhibitors for treating pulmonary and cardiovascular disorders
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405633A (en) * 1982-03-01 1983-09-20 Usv Pharmaceutical Corporation Method of treatment of asthma
US4490373A (en) * 1983-05-20 1984-12-25 Usv Pharmaceutical Corporation Method of treating asthma
SK45497A3 (en) * 1994-10-12 1997-10-08 Euro Celtique Sa Benzoxazoles, pharmaceutical composition containing them and their use
US6080782A (en) * 1995-05-18 2000-06-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Cyclohexyl dihydrobenzofuranes
PT771794E (pt) * 1995-05-19 2006-09-29 Kyowa Hakko Kogyo Kk Compostos heterociclicos contendo oxigenio

Also Published As

Publication number Publication date
JP2002519423A (ja) 2002-07-02
ATE263166T1 (de) 2004-04-15
SI1095040T1 (en) 2004-10-31
ZA200100088B (en) 2002-05-06
EP1095040B1 (de) 2004-03-31
PT1095040E (pt) 2004-08-31
EP1095040A1 (de) 2001-05-02
AU4778699A (en) 2000-01-24
DE69916066T2 (de) 2005-02-24
IL140468A0 (en) 2002-02-10
WO2000001695A1 (en) 2000-01-13
US6376485B1 (en) 2002-04-23
DE69916066D1 (de) 2004-05-06
AU761647B2 (en) 2003-06-05
CA2336894A1 (en) 2000-01-13
ES2219031T3 (es) 2004-11-16

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