PT1966130E - Compostos miméticos de lisina modificados - Google Patents
Compostos miméticos de lisina modificados Download PDFInfo
- Publication number
- PT1966130E PT1966130E PT68491521T PT06849152T PT1966130E PT 1966130 E PT1966130 E PT 1966130E PT 68491521 T PT68491521 T PT 68491521T PT 06849152 T PT06849152 T PT 06849152T PT 1966130 E PT1966130 E PT 1966130E
- Authority
- PT
- Portugal
- Prior art keywords
- benzamido
- carboxylic acid
- pyrrolidine
- aminoacetyl
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims description 215
- -1 2-amino-acetyl Chemical group 0.000 claims description 102
- 239000000203 mixture Substances 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 34
- 150000003839 salts Chemical class 0.000 claims description 25
- 125000000217 alkyl group Chemical group 0.000 claims description 19
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- 210000000056 organ Anatomy 0.000 claims description 7
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims description 6
- 206010003658 Atrial Fibrillation Diseases 0.000 claims description 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 5
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Classifications
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- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07K5/06—Dipeptides
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| EP2316839B1 (en) | 2004-07-16 | 2014-03-12 | Gilead Sciences, Inc. | Antiviral heterocyclic compounds having phosphonate groups |
| US7820699B2 (en) | 2005-04-27 | 2010-10-26 | Hoffmann-La Roche Inc. | Cyclic amines |
| CA2606785A1 (en) | 2005-05-19 | 2006-11-23 | Genentech, Inc. | Fibroblast activation protein inhibitor compounds and methods |
| CN101336229B (zh) * | 2005-12-23 | 2012-06-13 | 西兰岛药物有限公司 | 改性的拟赖氨酸化合物 |
| PL2468724T3 (pl) | 2006-12-21 | 2016-05-31 | Zealand Pharma As | Synteza związków pirolidynowych |
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2006
- 2006-12-21 CN CN2006800518550A patent/CN101336229B/zh active Active
- 2006-12-21 CA CA2634743A patent/CA2634743C/en active Active
- 2006-12-21 PL PL06849152T patent/PL1966130T3/pl unknown
- 2006-12-21 UA UAA200808527A patent/UA96283C2/uk unknown
- 2006-12-21 DK DK06849152.1T patent/DK1966130T3/da active
- 2006-12-21 EP EP06849152.1A patent/EP1966130B1/en active Active
- 2006-12-21 RU RU2008126246/04A patent/RU2494095C2/ru active
- 2006-12-21 CN CN201210106810.6A patent/CN102690221B/zh active Active
- 2006-12-21 WO PCT/US2006/048790 patent/WO2007078990A2/en not_active Ceased
- 2006-12-21 ES ES06849152.1T patent/ES2443242T3/es active Active
- 2006-12-21 EP EP11166328.2A patent/EP2386539B1/en active Active
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- 2006-12-21 PT PT68491521T patent/PT1966130E/pt unknown
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- 2006-12-22 TW TW095148422A patent/TWI411597B/zh active
- 2006-12-22 PE PE2006001691A patent/PE20070849A1/es not_active Application Discontinuation
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