PT1139793E - Inibidores da resposta ao sabor amargo - Google Patents
Inibidores da resposta ao sabor amargo Download PDFInfo
- Publication number
- PT1139793E PT1139793E PT99967519T PT99967519T PT1139793E PT 1139793 E PT1139793 E PT 1139793E PT 99967519 T PT99967519 T PT 99967519T PT 99967519 T PT99967519 T PT 99967519T PT 1139793 E PT1139793 E PT 1139793E
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitors
- bitter taste
- methods
- perception
- taste response
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/23—Synthetic spices, flavouring agents or condiments containing nucleotides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/82—Acid flavourants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11356298P | 1998-12-23 | 1998-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1139793E true PT1139793E (pt) | 2010-01-19 |
Family
ID=22350151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99967519T PT1139793E (pt) | 1998-12-23 | 1999-12-22 | Inibidores da resposta ao sabor amargo |
Country Status (11)
Country | Link |
---|---|
US (2) | US6540978B1 (pt) |
EP (1) | EP1139793B1 (pt) |
JP (1) | JP2002533693A (pt) |
AT (1) | ATE445335T1 (pt) |
AU (1) | AU2378600A (pt) |
CA (1) | CA2356533C (pt) |
DE (1) | DE69941544D1 (pt) |
DK (1) | DK1139793T3 (pt) |
ES (1) | ES2337322T3 (pt) |
PT (1) | PT1139793E (pt) |
WO (1) | WO2000038536A2 (pt) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
WO2001018050A2 (en) | 1999-09-10 | 2001-03-15 | The Regents Of The University Of California | T2r taste receptor family |
US7314716B2 (en) | 1999-11-19 | 2008-01-01 | Mount Sinai School Of Medicine | Gustducin γ subunit materials and methods |
TW201006846A (en) * | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
US20080244761A1 (en) * | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
US7301009B2 (en) * | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
US6955887B2 (en) | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
US6942874B2 (en) * | 2001-05-25 | 2005-09-13 | Linguagen Corp. | Nucleotide compounds that block the bitter taste of oral compositions |
DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
AU2002318229B2 (en) * | 2001-07-10 | 2008-03-13 | Senomyx, Inc. | Use of specific T2R taste receptors to identify compounds that block bitter taste |
EP1523308A4 (en) | 2001-07-20 | 2007-01-10 | Us Gov Health & Human Serv | PHENYL THIOCARBAMIDE (PTC) TREATMENT RECEPTOR |
CA2534027A1 (en) | 2003-06-19 | 2005-01-27 | Dennis Drayna | Variants of human taste receptor genes |
EP1706086A1 (en) * | 2004-01-21 | 2006-10-04 | 3M Innovative Properties Company | Dental compositions and kits containing bitterness inhibitors, and related methods |
US7156911B2 (en) | 2004-05-17 | 2007-01-02 | 3M Innovative Properties Company | Dental compositions containing nanofillers and related methods |
US7649029B2 (en) * | 2004-05-17 | 2010-01-19 | 3M Innovative Properties Company | Dental compositions containing nanozirconia fillers |
US7090722B2 (en) * | 2004-05-17 | 2006-08-15 | 3M Innovative Properties Company | Acid-reactive dental fillers, compositions, and methods |
US7090721B2 (en) * | 2004-05-17 | 2006-08-15 | 3M Innovative Properties Company | Use of nanoparticles to adjust refractive index of dental compositions |
CN101155515A (zh) * | 2005-01-17 | 2008-04-02 | 诺维信北美公司 | 风味增强的方法 |
JP5432455B2 (ja) * | 2005-02-25 | 2014-03-05 | ザ ステート オブ イスラエル、ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント、アグリカルチュラル リサーチ オーガナイゼイション、(エー.アール.オー.)、ボルカニ センター | 炎症治療用の果実細胞培養抽出物 |
WO2006096690A2 (en) * | 2005-03-07 | 2006-09-14 | University Of Rochester | Compositions and methods for inhibiting g protein signaling |
US7452563B2 (en) * | 2005-06-20 | 2008-11-18 | Redpoint Bio Corporation | Compositions and methods for producing flavored seasonings that contain reduced quantities of common salt |
US7455872B2 (en) | 2005-06-20 | 2008-11-25 | Redpoint Bio Corporation | Compositions and methods for producing a salty taste in foods or beverages |
CA2626846A1 (en) * | 2005-11-03 | 2007-05-18 | Redpoint Bio Corporation | Hydrazone derivatives and uses thereof |
US8956677B2 (en) * | 2005-11-23 | 2015-02-17 | The Coca-Cola Company | High-potency sweetener composition with glucosamine and compositions sweetened therewith |
US8993027B2 (en) * | 2005-11-23 | 2015-03-31 | The Coca-Cola Company | Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses |
US20070116822A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-potency sweetener composition with saponin and compositions sweetened therewith |
US20070116836A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith |
US20070134391A1 (en) * | 2005-11-23 | 2007-06-14 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith |
US20070116831A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Dental Composition with High-Potency Sweetener |
EP1965667A2 (en) * | 2005-11-23 | 2008-09-10 | The Coca-Cola Company | Synthetic sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses |
US20070116825A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Confection with High-Potency Sweetener |
US9144251B2 (en) * | 2005-11-23 | 2015-09-29 | The Coca-Cola Company | High-potency sweetener composition with mineral and compositions sweetened therewith |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
WO2007065101A1 (en) * | 2005-11-30 | 2007-06-07 | Axitare, Inc. | Compositions and methods of modulating the taste and smell receptors and screening methods therefore |
AU2007261973B8 (en) * | 2006-06-21 | 2012-01-19 | Adeka Corporation | Taste improving agent |
US20080070865A1 (en) * | 2006-09-15 | 2008-03-20 | Redpoint Bio Corporation | Triphenylphosphine oxide derivatives and uses thereof |
US20080153845A1 (en) * | 2006-10-27 | 2008-06-26 | Redpoint Bio Corporation | Trpv1 antagonists and uses thereof |
US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
US9101161B2 (en) * | 2006-11-02 | 2015-08-11 | The Coca-Cola Company | High-potency sweetener composition with phytoestrogen and compositions sweetened therewith |
US20080107787A1 (en) * | 2006-11-02 | 2008-05-08 | The Coca-Cola Company | Anti-Diabetic Composition with High-Potency Sweetener |
EP2107908A4 (en) * | 2007-02-02 | 2011-07-20 | Redpoint Bio Corp | USE OF A TRPM5 INHIBITOR TO REGULATE INSULIN AND GLP-1 SECRETION |
CN101998833A (zh) * | 2008-02-06 | 2011-03-30 | 金宝汤公司 | 用于减少食物制品中钠含量的方法和组合物 |
JP5564167B2 (ja) * | 2008-05-22 | 2014-07-30 | 日本たばこ産業株式会社 | 苦味マスキング剤及び苦味低減方法 |
CN102460150B (zh) | 2009-04-20 | 2015-05-20 | 新加坡科技研究局 | 囊泡系统及其用途 |
US9128079B2 (en) | 2011-08-08 | 2015-09-08 | The Coca-Cola Company | Methods of using lung or bronchial epithelial cells to identify bitter taste modulators |
JP6122858B2 (ja) * | 2011-10-20 | 2017-04-26 | クロモセル コーポレーション | 苦味を調整する化合物を同定するための検定 |
WO2013112865A1 (en) * | 2012-01-27 | 2013-08-01 | The Trustees Of The University Of Pennsylvania | Diagnosis and treatment for respiratory tract diseases |
WO2013143822A1 (en) | 2012-03-26 | 2013-10-03 | Imax Discovery Gmbh | Adenosine as sweetness enhancer for certain sugars |
CN103005367A (zh) * | 2012-12-17 | 2013-04-03 | 楚大波 | 一种苦味遮蔽剂及其制备方法及用途 |
US9668505B2 (en) * | 2013-02-18 | 2017-06-06 | Acme Specialty Products, Llc | Taste masking compositions and edible forms thereof for masking the taste of foods |
US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
CA2910161A1 (en) | 2013-04-24 | 2014-10-30 | Chromocell Corporation | Assays for identifying compounds that modulate bitter taste |
PE20231574A1 (es) * | 2023-02-24 | 2023-10-04 | Agrovet Market S A | Composicion farmaceutica que comprende fluralaner, moxidectina y praziquantel para el tratamiento de infestaciones parasitarias en animales menores |
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JPS4810227B1 (pt) * | 1964-02-27 | 1973-04-02 | ||
CH497136A (de) * | 1966-04-18 | 1970-10-15 | Takeda Chemical Industries Ltd | Verfahren zur Unterdrückung des bitteren Geschmackes von geniessbaren Substanzen |
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DE19646392A1 (de) | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
DE19652268C2 (de) | 1996-12-16 | 2000-06-29 | Lohmann Therapie Syst Lts | Arzneizubereitung für die Freisetzung von Apomorphin in der Mundhöhle |
JP4034865B2 (ja) | 1997-12-15 | 2008-01-16 | 株式会社興人 | 食品の香りをマスキングする方法 |
US6596298B2 (en) | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
US6541050B1 (en) | 1998-11-27 | 2003-04-01 | Campbell Soup Company | Salt flavor enhancing compositions, food products including such compositions, and methods for preparing such products |
JP3427775B2 (ja) | 1999-04-15 | 2003-07-22 | 日本製紙株式会社 | コク味付与剤 |
WO2000069283A1 (en) | 1999-05-13 | 2000-11-23 | The Nutrasweet Company | USE OF ADDITIVES TO MODIFY THE TASTE CHARACTERISTICS OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER |
US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
US7314716B2 (en) | 1999-11-19 | 2008-01-01 | Mount Sinai School Of Medicine | Gustducin γ subunit materials and methods |
JP4182644B2 (ja) | 2001-02-09 | 2008-11-19 | 味の素株式会社 | 調味料組成物およびそれを用いてなる食品の製造方法 |
US20030035875A1 (en) | 2001-04-03 | 2003-02-20 | Dulebohn Joel I. | Composition for improving the taste and sweetness profile of beverages having intense sweeteners |
US6942874B2 (en) | 2001-05-25 | 2005-09-13 | Linguagen Corp. | Nucleotide compounds that block the bitter taste of oral compositions |
US20030194423A1 (en) | 2002-04-15 | 2003-10-16 | Mars, Inc. | Composition for enhancing nutritional content of food |
-
1999
- 1999-12-22 AT AT99967519T patent/ATE445335T1/de active
- 1999-12-22 DK DK99967519.2T patent/DK1139793T3/da active
- 1999-12-22 WO PCT/US1999/030610 patent/WO2000038536A2/en active Application Filing
- 1999-12-22 US US09/470,467 patent/US6540978B1/en not_active Ceased
- 1999-12-22 CA CA2356533A patent/CA2356533C/en not_active Expired - Fee Related
- 1999-12-22 DE DE69941544T patent/DE69941544D1/de not_active Expired - Fee Related
- 1999-12-22 AU AU23786/00A patent/AU2378600A/en not_active Abandoned
- 1999-12-22 PT PT99967519T patent/PT1139793E/pt unknown
- 1999-12-22 JP JP2000590498A patent/JP2002533693A/ja active Pending
- 1999-12-22 EP EP99967519A patent/EP1139793B1/en not_active Expired - Lifetime
- 1999-12-22 ES ES99967519T patent/ES2337322T3/es not_active Expired - Lifetime
-
2006
- 2006-03-28 US US11/391,670 patent/USRE40594E1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2002533693A (ja) | 2002-10-08 |
CA2356533C (en) | 2010-07-13 |
USRE40594E1 (en) | 2008-12-02 |
ES2337322T3 (es) | 2010-04-22 |
WO2000038536A2 (en) | 2000-07-06 |
EP1139793A2 (en) | 2001-10-10 |
AU2378600A (en) | 2000-07-31 |
ATE445335T1 (de) | 2009-10-15 |
WO2000038536A3 (en) | 2000-11-16 |
DK1139793T3 (da) | 2010-03-01 |
DE69941544D1 (de) | 2009-11-26 |
US6540978B1 (en) | 2003-04-01 |
CA2356533A1 (en) | 2000-07-06 |
EP1139793B1 (en) | 2009-10-14 |
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