PT106679B - Formulações tópicas de tetraciclinas, sua preparação e usos - Google Patents

Formulações tópicas de tetraciclinas, sua preparação e usos Download PDF

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Publication number
PT106679B
PT106679B PT106679A PT10667912A PT106679B PT 106679 B PT106679 B PT 106679B PT 106679 A PT106679 A PT 106679A PT 10667912 A PT10667912 A PT 10667912A PT 106679 B PT106679 B PT 106679B
Authority
PT
Portugal
Prior art keywords
formulation
topical
minocycline
suspension
microns
Prior art date
Application number
PT106679A
Other languages
English (en)
Portuguese (pt)
Other versions
PT106679A (pt
Inventor
Mohammad Salman
Arturo Angel
Vijaya Swaminathan
Original Assignee
Hovione Farmaciencia Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49620233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT106679(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hovione Farmaciencia Sa filed Critical Hovione Farmaciencia Sa
Priority to PT106679A priority Critical patent/PT106679B/pt
Priority to ES13792728.1T priority patent/ES2645449T3/es
Priority to KR1020157017068A priority patent/KR102235922B1/ko
Priority to US14/074,868 priority patent/US9592246B2/en
Priority to CN201380068453.1A priority patent/CN104902875B/zh
Priority to PL13792728T priority patent/PL2925293T3/pl
Priority to NO13792728A priority patent/NO2925293T3/no
Priority to CA2895395A priority patent/CA2895395C/en
Priority to JP2015543515A priority patent/JP6444308B2/ja
Priority to BR112015012162-4A priority patent/BR112015012162B1/pt
Priority to SG11201504145PA priority patent/SG11201504145PA/en
Priority to AU2013350941A priority patent/AU2013350941B2/en
Priority to NZ708824A priority patent/NZ708824A/en
Priority to PCT/GB2013/052939 priority patent/WO2014083311A1/en
Priority to HUE13792728A priority patent/HUE034932T2/en
Priority to RU2015122786A priority patent/RU2639591C2/ru
Priority to MX2015006632A priority patent/MX355174B/es
Priority to DK13792728.1T priority patent/DK2925293T3/da
Priority to EP13792728.1A priority patent/EP2925293B1/en
Publication of PT106679A publication Critical patent/PT106679A/pt
Publication of PT106679B publication Critical patent/PT106679B/pt
Priority to IL239022A priority patent/IL239022B/en
Priority to ZA2015/04369A priority patent/ZA201504369B/en
Priority to US15/457,809 priority patent/US10213443B2/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT106679A 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos PT106679B (pt)

Priority Applications (22)

Application Number Priority Date Filing Date Title
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos
EP13792728.1A EP2925293B1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
SG11201504145PA SG11201504145PA (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
NZ708824A NZ708824A (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
US14/074,868 US9592246B2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
CN201380068453.1A CN104902875B (zh) 2012-11-27 2013-11-08 四环素局部制剂、其制备及用途
PL13792728T PL2925293T3 (pl) 2012-11-27 2013-11-08 Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania
NO13792728A NO2925293T3 (https=) 2012-11-27 2013-11-08
CA2895395A CA2895395C (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
JP2015543515A JP6444308B2 (ja) 2012-11-27 2013-11-08 テトラサイクリン局所製剤、その調製及び使用
BR112015012162-4A BR112015012162B1 (pt) 2012-11-27 2013-11-08 formulação de suspensão tópica e formulação de suspensão de minociclina tópica para usar no tratamento de acne vulgaris
ES13792728.1T ES2645449T3 (es) 2012-11-27 2013-11-08 Formulaciones tópicas de tetraciclina, preparación y usos de las mismas
AU2013350941A AU2013350941B2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
KR1020157017068A KR102235922B1 (ko) 2012-11-27 2013-11-08 테트라사이클린 국소 제제, 제조방법, 및 이의 용도
PCT/GB2013/052939 WO2014083311A1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
HUE13792728A HUE034932T2 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
RU2015122786A RU2639591C2 (ru) 2012-11-27 2013-11-08 Тетрациклиновые композиции для местного применения, их получение и применение
MX2015006632A MX355174B (es) 2012-11-27 2013-11-08 Formulaciones de uso topico de tetraciclina, preparaciones y usos de las mismas.
DK13792728.1T DK2925293T3 (da) 2012-11-27 2013-11-08 Topiske tetracyclinformuleringer, fremstilling og anvendelser deraf
IL239022A IL239022B (en) 2012-11-27 2015-05-26 Tetracycline topical formulations, preparation and uses thereof
ZA2015/04369A ZA201504369B (en) 2012-11-27 2015-06-17 Tetracycline topical formulations, preparation and uses thereof
US15/457,809 US10213443B2 (en) 2012-11-27 2017-03-13 Tetracycline topical formulations, preparation and uses thereof in treating an ocular condition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos

Publications (2)

Publication Number Publication Date
PT106679A PT106679A (pt) 2014-05-27
PT106679B true PT106679B (pt) 2015-03-25

Family

ID=49620233

Family Applications (1)

Application Number Title Priority Date Filing Date
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos

Country Status (21)

Country Link
US (2) US9592246B2 (https=)
EP (1) EP2925293B1 (https=)
JP (1) JP6444308B2 (https=)
KR (1) KR102235922B1 (https=)
CN (1) CN104902875B (https=)
AU (1) AU2013350941B2 (https=)
BR (1) BR112015012162B1 (https=)
CA (1) CA2895395C (https=)
DK (1) DK2925293T3 (https=)
ES (1) ES2645449T3 (https=)
HU (1) HUE034932T2 (https=)
IL (1) IL239022B (https=)
MX (1) MX355174B (https=)
NO (1) NO2925293T3 (https=)
NZ (1) NZ708824A (https=)
PL (1) PL2925293T3 (https=)
PT (1) PT106679B (https=)
RU (1) RU2639591C2 (https=)
SG (1) SG11201504145PA (https=)
WO (1) WO2014083311A1 (https=)
ZA (1) ZA201504369B (https=)

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MX377365B (es) 2016-09-08 2025-03-10 Journey Medical Corp Composiciones y métodos para tratar rosácea y acné.
FR3064482B1 (fr) * 2017-04-03 2020-11-13 Horus Pharma Composition topique de doxycycline
MX2020004187A (es) * 2017-10-24 2020-09-21 Glenmark Pharmaceuticals Ltd Composicion farmaceutica topica de adapaleno y minociclina.
WO2019106036A1 (en) 2017-11-28 2019-06-06 C-Lecta Gmbh Method for producing trehalose employing a trehalose phosphorylase variant
JP7561029B2 (ja) 2018-01-07 2024-10-03 ドクター レディズ ラボラトリーズ リミテッド 炎症性皮膚状態を処置するためのミノサイクリン
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WO2021191273A1 (en) 2020-03-24 2021-09-30 Hovione Scientia Limited Compositions for use in treating meibomian gland dysfunction
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WO2022090302A1 (en) * 2020-10-28 2022-05-05 Hovione Scientia Limited Methods and compositions for treating meibomian gland dysfunction, dry eye disease, and related disorders
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