PL2925293T3 - Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania - Google Patents

Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania

Info

Publication number
PL2925293T3
PL2925293T3 PL13792728T PL13792728T PL2925293T3 PL 2925293 T3 PL2925293 T3 PL 2925293T3 PL 13792728 T PL13792728 T PL 13792728T PL 13792728 T PL13792728 T PL 13792728T PL 2925293 T3 PL2925293 T3 PL 2925293T3
Authority
PL
Poland
Prior art keywords
preparation
topical formulations
tetracycline
tetracycline topical
formulations
Prior art date
Application number
PL13792728T
Other languages
English (en)
Inventor
Mohammad Salman
Arturo Angel
Vijaya Swaminathan
Original Assignee
Hovione Scientia Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49620233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2925293(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hovione Scientia Limited filed Critical Hovione Scientia Limited
Publication of PL2925293T3 publication Critical patent/PL2925293T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL13792728T 2012-11-27 2013-11-08 Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania PL2925293T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT106679A PT106679B (pt) 2012-11-27 2012-11-27 Formulações tópicas de tetraciclinas, sua preparação e usos
PCT/GB2013/052939 WO2014083311A1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof
EP13792728.1A EP2925293B1 (en) 2012-11-27 2013-11-08 Tetracycline topical formulations, preparation and uses thereof

Publications (1)

Publication Number Publication Date
PL2925293T3 true PL2925293T3 (pl) 2017-12-29

Family

ID=49620233

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13792728T PL2925293T3 (pl) 2012-11-27 2013-11-08 Formulacje tetracykliny do stosowania miejscowego, ich przygotowanie i zastosowania

Country Status (21)

Country Link
US (2) US9592246B2 (pl)
EP (1) EP2925293B1 (pl)
JP (1) JP6444308B2 (pl)
KR (1) KR102235922B1 (pl)
CN (1) CN104902875B (pl)
AU (1) AU2013350941B2 (pl)
BR (1) BR112015012162B1 (pl)
CA (1) CA2895395C (pl)
DK (1) DK2925293T3 (pl)
ES (1) ES2645449T3 (pl)
HU (1) HUE034932T2 (pl)
IL (1) IL239022B (pl)
MX (1) MX355174B (pl)
NO (1) NO2925293T3 (pl)
NZ (1) NZ708824A (pl)
PL (1) PL2925293T3 (pl)
PT (1) PT106679B (pl)
RU (1) RU2639591C2 (pl)
SG (1) SG11201504145PA (pl)
WO (1) WO2014083311A1 (pl)
ZA (1) ZA201504369B (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
ES2532906T5 (es) 2002-10-25 2022-03-23 Foamix Pharmaceuticals Ltd Espuma cosmética y farmacéutica
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
EP2482788B1 (en) 2009-10-02 2022-12-14 Journey Medical Corporation Topical tetracycline compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
CA2970502A1 (en) * 2014-12-12 2016-06-16 The Schepens Eye Research Institute, Inc. Gdnf induction for the treatment of retinal disorders
US10512608B2 (en) 2015-02-25 2019-12-24 Sun Pharma Advanced Research Company Ltd. Nanoparticulate composition
AU2016235237B2 (en) 2015-03-23 2021-03-11 BioPharmX, Inc. Pharmaceutical tetracycline composition for dermatological use
CN105380900B (zh) * 2015-11-25 2018-05-29 徐州医学院 一种治疗痤疮的纳米磁疗外用凝胶及其制备方法和应用
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
FR3064482B1 (fr) * 2017-04-03 2020-11-13 Horus Pharma Composition topique de doxycycline
MX2020004187A (es) * 2017-10-24 2020-09-21 Glenmark Pharmaceuticals Ltd Composicion farmaceutica topica de adapaleno y minociclina.
EP3717655A1 (en) 2017-11-28 2020-10-07 c-LEcta GmbH Method for producing trehalose employing a trehalose phosphorylase variant
WO2019135166A1 (en) 2018-01-07 2019-07-11 Dr. Reddy's Laboratories Ltd. Minocycline for treating inflammatory skin conditions
JP7506679B2 (ja) 2018-10-29 2024-06-26 フラウンホーファー－ゲゼルシャフト・ツール・フェルデルング・デル・アンゲヴァンテン・フォルシュング・アインゲトラーゲネル・フェライン 持続性活性を有するテトラサイクリン複合体
US11202788B2 (en) 2019-08-22 2021-12-21 Nanopharmaceutics, Inc. Topical doxycycline hydrogel with improved long-term stability
WO2021191273A1 (en) 2020-03-24 2021-09-30 Hovione Scientia Limited Compositions for use in treating meibomian gland dysfunction
WO2022043457A1 (en) 2020-08-27 2022-03-03 Hovione Scientia Limited Methods and compositions for treating rosacea
WO2022090302A1 (en) * 2020-10-28 2022-05-05 Hovione Scientia Limited Methods and compositions for treating meibomian gland dysfunction, dry eye disease, and related disorders
CN115463091B (zh) * 2022-10-27 2023-04-07 新基元(北京)医药科技有限公司 一种改善稳定性的米诺环素泡沫剂

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB769274A (en) * 1954-04-22 1957-03-06 Pfizer Therapeutic preparations of tetracycline antibiotics in oil
GB1581335A (en) 1976-07-05 1980-12-10 Leo Pharm Prod Ltd 16-s-acyl derivatives of fusidic acid
US4505896A (en) 1979-04-19 1985-03-19 Elorac, Ltd. Method of treating acne vulgaris and composition
JPS5788115A (en) * 1980-10-06 1982-06-01 Miles Lab Stable non-aqueous solution of tetracycline antibiotic salt
US5122519A (en) 1989-06-27 1992-06-16 American Cyanamid Company Stable, cosmetically acceptable topical gel formulation and method of treatment for acne
US5874479A (en) 1991-03-01 1999-02-23 Warner-Lambert Company Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
US6113921A (en) 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
US5905092A (en) 1994-09-27 1999-05-18 Virotex Corporation Reel/Frame Topical antibiotic composition providing optimal moisture environment for rapid wound healing that reduces skin contraction
US5747058A (en) 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
EP0884997B1 (en) * 1996-02-16 2002-06-05 Janssen Pharmaceutica N.V. Compositions containing an antifungal and a sulfur compound
JPH09255578A (ja) * 1996-03-22 1997-09-30 Sekisui Chem Co Ltd 感染性皮膚疾患治療用外用剤
US5834008A (en) 1996-09-19 1998-11-10 U.S. Biomaterials Corp. Composition and method for acceleration of wound and burn healing
US6433068B1 (en) * 1997-03-07 2002-08-13 David S. Morrison Hydrocarbon gels as suspending and dispersing agents and products
PT1676579E (pt) * 1998-05-08 2009-03-24 Univ Miami Utilização de tetraciclinas sub-antimicrobianas para o tratamento de rosácea ocular
US20030007939A1 (en) 1998-07-31 2003-01-09 Howard Murad Pharmaceutical compositions and methods for managing dermatological conditions
US6432934B1 (en) * 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
CN1320046A (zh) * 1999-07-12 2001-10-31 三得利株式会社 局部给药的药用组合物
US6946118B1 (en) 1999-09-14 2005-09-20 Orapharma, Inc. Formulations for treating or preventing mucositis
US6667045B2 (en) 1999-10-01 2003-12-23 Joseph Scott Dahle Topical applications for skin treatment
US20030077301A1 (en) 1999-12-16 2003-04-24 Maibach Howard I. Topical pharmaceutical composition for the treatment of inflammatory dermatoses
US6967023B1 (en) 2000-01-10 2005-11-22 Foamix, Ltd. Pharmaceutical and cosmetic carrier or composition for topical application
US20020010162A1 (en) 2000-03-02 2002-01-24 Raul Fleischmajer Treatment of psoriasis with matrix metalloproteinase inhibitors
US7758888B2 (en) 2000-04-21 2010-07-20 Sol-Gel Technologies Ltd. Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
JP4653282B2 (ja) * 2000-05-23 2011-03-16 昭和薬品化工株式会社 ミノサイクリン含有組成物
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
AU2002317053B2 (en) 2001-07-27 2004-08-05 Vital Health Sciences Pty Ltd Dermal therapy using phosphate derivatives of electron transfer agents
KR20050026401A (ko) 2002-06-17 2005-03-15 비큐론 파마세티컬스 인코포레이티드 여드름 치료를 위한 ｇｅ 2270 인자 ａ3의 아미드유도체의 용도
US20040076699A1 (en) * 2002-07-15 2004-04-22 Chaudhuri Ratan K. Topical anhydrous delivery system
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
KR100738264B1 (ko) 2003-06-11 2007-07-12 더 프록터 앤드 갬블 캄파니 예비형성된 하이드로겔 제품을 포함하는 사용시-제조 장치
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US7241746B2 (en) 2003-08-06 2007-07-10 Regena Therapeutics, Lc Method and composition for treating periodontal disease
WO2006035320A2 (en) 2004-09-27 2006-04-06 Jan De Rijk Methods and compositions for treatment of water
US7531164B2 (en) 2005-10-21 2009-05-12 Duke University Preventing bacterial or viral infectivity and composition containing infection preventing additive
GB2432529B (en) 2005-11-25 2008-04-23 Univ Feng Chia Antimicrobial compositions and wound dressings
JP4959991B2 (ja) * 2006-03-03 2012-06-27 株式会社日本点眼薬研究所 トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物
US20080188445A1 (en) 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
WO2008097851A1 (en) * 2007-02-02 2008-08-14 Warner Chilcott Company, Inc. Tetracycline compositions for topical administration
AU2008219600A1 (en) 2007-02-28 2008-09-04 Aciex Therapeutics, Inc. Methods and compositions for normalizing meibomian gland secretions
KR20090122994A (ko) * 2007-03-23 2009-12-01 몰레큘러 리서치 센터, 인크. 테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도
HRP20100699T1 (hr) 2007-07-25 2011-01-31 Ixodes Gmbh Topikalni antibioticki sastav za prevenciju lajmske bolesti
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
GB0800145D0 (en) * 2008-01-04 2008-02-13 Reckitt Benckiser Uk Ltd Skincare treatment
KR20100127300A (ko) * 2008-03-28 2010-12-03 안게스 엠지 인코포레이티드 전사 인자 디코이를 유효 성분으로 하는 외용제 조성물
US9149660B2 (en) * 2008-04-29 2015-10-06 Hair Systems Inc. Composition and method for cream bleach product
US20100029765A1 (en) 2008-07-30 2010-02-04 Ranbaxy Labortories Limited Topical aqueous composition comprising tretinoin
CA2734687A1 (en) * 2008-08-18 2010-02-25 Nanotherapeutics, Inc. Topical hydrogel composition
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
PT104644B (pt) 2009-06-26 2012-11-06 Hovione Farmaciencia S A Formulação tópica contendo uma tetraciclina e método de tratamento de infecções cutâneas usando a mesma
US9155915B2 (en) 2009-07-27 2015-10-13 Dermadoctor, Inc. Moisturizing retinol composition
EP2482788B1 (en) 2009-10-02 2022-12-14 Journey Medical Corporation Topical tetracycline compositions
GB2474930B (en) * 2009-10-02 2012-07-04 Foamix Ltd Topical tetracycline compositions
WO2011106697A1 (en) 2010-02-25 2011-09-01 Schepens Eye Research Institute Therapeutic compositions for the treatment of dry eye disease
US20120076766A1 (en) 2010-04-21 2012-03-29 Phillips D Howard Topical drug delivery system with dual carriers
US20130053353A1 (en) 2010-05-04 2013-02-28 Foamix Ltd. Compositions, gels and foams with rheology modulators and uses
PT105116B (pt) 2010-05-14 2012-10-16 Hovione Farmaciencia S A Novas partículas de tetraciclina e agente protector.
BRPI1002601E2 (pt) 2010-06-01 2020-06-30 Embrapa Pesquisa Agropecuaria composição nanoestruturada de uso veterinário para administração de fármacos
US20120093876A1 (en) 2010-10-13 2012-04-19 Aciex, Inc. Ophthalmic Formulations, Methods Of Manufacture And Methods of Normalizing Meibomian Gland Secretions
CA2719512A1 (en) 2010-11-01 2012-05-01 Stiefel Research Australia Pty Ltd Polymeric topical compositions
EP2667945A1 (en) * 2011-01-24 2013-12-04 Anterios, Inc. Oil compositions

Also Published As

Publication number Publication date
CA2895395A1 (en) 2014-06-05
NZ708824A (en) 2019-01-25
US20140147504A1 (en) 2014-05-29
US10213443B2 (en) 2019-02-26
ZA201504369B (en) 2017-01-25
US9592246B2 (en) 2017-03-14
EP2925293B1 (en) 2017-08-02
IL239022A0 (en) 2015-07-30
MX355174B (es) 2018-04-09
DK2925293T3 (da) 2017-11-06
PT106679A (pt) 2014-05-27
HUE034932T2 (en) 2018-03-28
CA2895395C (en) 2021-04-06
SG11201504145PA (en) 2015-07-30
US20170182071A1 (en) 2017-06-29
CN104902875A (zh) 2015-09-09
RU2015122786A (ru) 2017-01-10
PT106679B (pt) 2015-03-25
IL239022B (en) 2020-11-30
KR20150104102A (ko) 2015-09-14
MX2015006632A (es) 2016-02-17
KR102235922B1 (ko) 2021-04-05
CN104902875B (zh) 2018-04-03
NO2925293T3 (pl) 2017-12-30
JP2016500095A (ja) 2016-01-07
AU2013350941A1 (en) 2015-07-16
AU2013350941B2 (en) 2018-04-26
EP2925293A1 (en) 2015-10-07
ES2645449T3 (es) 2017-12-05
RU2639591C2 (ru) 2017-12-21
BR112015012162B1 (pt) 2021-02-23
JP6444308B2 (ja) 2018-12-26
WO2014083311A1 (en) 2014-06-05

Similar Documents

Publication Publication Date Title
IL289759A (en) Formulations for local disinfection and their uses
ZA201504369B (en) Tetracycline topical formulations, preparation and uses thereof
IL227625A0 (en) Nanoparticle compounds, their formulations, and their use
IL234014A0 (en) Cycloalkane derivatives, preparations containing them and their uses
IL235409A0 (en) Topical non-aqueous pharmaceutical formulations
IL237287A0 (en) Antibody compositions and their uses
ZA201501124B (en) Trans-clomiphene formulations and uses thereof
ZA201407655B (en) Topical pharmaceutical compositions comprising terbinafine and urea
ZA201509307B (en) Pharmaceutical composition, preparation and uses thereof
IL233824A (en) Compounds 1h - Indazole - 3 - Carboxamide, preparations containing them and their use
IL233602A0 (en) History of benzamide, their preparation and pharmaceutical preparations containing them
IL237542A0 (en) Amphiphilic compounds, their preparations and uses
EP2766183A4 (en) IRON FIBER COMPOSITION, PREPARATION THEREOF AND USES THEREOF
IL237540B (en) Amphiphilic compounds, their preparations and uses
IL233682A0 (en) Modified phenylazole derivatives, preparations containing them and their uses
IL237539A0 (en) Amphiphilic compounds, their preparations and uses
IL237538B (en) Amphiphilic compounds, their preparations and uses
GB201208384D0 (en) Vesicular formulations, uses and methods
ZA201502882B (en) Topical parasiticidal formulation
IL235752A0 (en) Dronedrone for use in leishmaniasis, formulations and associations for use in leishmaniasis
IL284405A (en) Pharmaceutical composition, preparation and uses thereof
EP2603077A4 (en) VEGETABLE TOPICAL FORMULATION
GB201222922D0 (en) Topical formulation
AU2012900140A0 (en) Pharmaceutical compositions and topical use thereof
GB201204597D0 (en) Topical pharmaceutical formulation