PT101654B - Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona - Google Patents

Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona Download PDF

Info

Publication number
PT101654B
PT101654B PT101654A PT10165495A PT101654B PT 101654 B PT101654 B PT 101654B PT 101654 A PT101654 A PT 101654A PT 10165495 A PT10165495 A PT 10165495A PT 101654 B PT101654 B PT 101654B
Authority
PT
Portugal
Prior art keywords
tetrahydro
pyrimidin
pyrido
methyl
ethyl
Prior art date
Application number
PT101654A
Other languages
English (en)
Portuguese (pt)
Other versions
PT101654A (pt
Inventor
Pere Dalmases Barjoan
Francisco Marquillas Olondriz
Ana Bosch Rovira
Jose Maria Caldero Ges
Juan Huguet Clotet
Juan Carlos Del Castillo Nieto
Original Assignee
Vita Invest Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Invest Sa filed Critical Vita Invest Sa
Publication of PT101654A publication Critical patent/PT101654A/pt
Publication of PT101654B publication Critical patent/PT101654B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT101654A 1994-02-11 1995-02-09 Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona PT101654B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09400252A ES2074966B1 (es) 1994-02-11 1994-02-11 Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.

Publications (2)

Publication Number Publication Date
PT101654A PT101654A (pt) 1995-09-12
PT101654B true PT101654B (pt) 2002-01-30

Family

ID=8285178

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101654A PT101654B (pt) 1994-02-11 1995-02-09 Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona

Country Status (14)

Country Link
KR (1) KR100221108B1 (de)
AT (1) AT405401B (de)
CZ (1) CZ286398B6 (de)
EG (1) EG20877A (de)
ES (1) ES2074966B1 (de)
FI (1) FI110000B (de)
GR (1) GR1002344B (de)
HU (1) HU222110B1 (de)
IS (1) IS1766B (de)
NO (1) NO306022B1 (de)
PL (1) PL181420B1 (de)
PT (1) PT101654B (de)
RU (1) RU2123004C1 (de)
SK (1) SK281752B6 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2101646B1 (es) * 1995-04-12 1998-04-01 Ferrer Int Nuevo compuesto derivado del cromeno.
ES2144355B1 (es) * 1997-12-30 2001-01-01 Ferrer Int Compuestos derivados del cromeno.
DE60009959T2 (de) * 2000-05-05 2005-03-31 Rpg Life Sciences Limited Verfahren zur herstellung von antipsychotischem 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-on
PL365608A1 (en) 2000-08-14 2005-01-10 Teva Pharmaceutical Industries Ltd. Preparation of risperidone
ES2197801B1 (es) * 2002-03-05 2005-03-16 Ferrer Internacional,S.A Procedimiento de obtencion de la 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il) piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a ) pirimidin-4-ona.
KR20040034996A (ko) 2002-10-18 2004-04-29 한미약품 주식회사 리스페리돈의 개선된 제조방법
CN100390146C (zh) 2002-11-13 2008-05-28 斯索恩有限公司 制备利培酮的方法和用于该方法的中间体
RU2310653C1 (ru) * 2006-07-17 2007-11-20 Государственное образовательное учреждение высшего профессионального образования "Кубанский государственный технологический университет" (ГОУВПО "КубГТУ") СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 2-МЕТИЛ-5-(5-МЕТИЛ-2-ФУРИЛ)-4,10-ДИГИДРО-3H-ПИРИДАЗИНО[1,6-b]ИЗОХИНОЛИН-10-ОНА (ВАРИАНТЫ)
BRPI0809837A2 (pt) * 2007-04-19 2014-11-11 Youxin Li "composto para tratamento de distúrbios mentais, saldo do composto para tratamento de distúrbios mentais, composição farmacéutica e uso do composto para tratamento de distúrbios mentais"

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT327199B (de) * 1971-10-14 1976-01-26 Sumitomo Chemical Co Verfahren zur herstellung von neuen nitrochinazolinonen
US4352811A (en) * 1981-11-12 1982-10-05 Hoechst-Roussel Pharmaceuticals Inc. 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles
US4485107A (en) * 1982-11-01 1984-11-27 Janssen Pharmaceutica N.V. [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US4980365A (en) * 1987-07-13 1990-12-25 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents

Also Published As

Publication number Publication date
CZ32995A3 (en) 1995-09-13
NO950501L (no) 1995-08-14
KR950032196A (ko) 1995-12-20
FI950579A0 (fi) 1995-02-10
ES2074966A1 (es) 1995-09-16
EG20877A (en) 2000-05-31
ES2074966B1 (es) 1996-06-16
SK281752B6 (sk) 2001-07-10
FI950579L (fi) 1995-08-12
GR1002344B (el) 1996-05-24
PL181420B1 (pl) 2001-07-31
IS1766B (is) 2001-03-15
AT405401B (de) 1999-08-25
FI110000B (fi) 2002-11-15
HU9500418D0 (en) 1995-03-28
HUT70169A (en) 1995-09-28
SK15695A3 (en) 1995-10-11
CZ286398B6 (en) 2000-04-12
NO306022B1 (no) 1999-09-06
RU2123004C1 (ru) 1998-12-10
RU95101859A (ru) 1997-03-20
PT101654A (pt) 1995-09-12
IS4259A (is) 1995-08-12
ATA24995A (de) 1998-12-15
HU222110B1 (hu) 2003-04-28
PL307200A1 (en) 1995-08-21
NO950501D0 (no) 1995-02-09
KR100221108B1 (ko) 1999-09-15

Similar Documents

Publication Publication Date Title
US4954503A (en) 3-(1-substituted-4-piperazinyl)-1H-indazoles
FI104072B (fi) Menetelmä terapeuttisesti käyttökelpoisten N-(aryylioksialkyyli)heteroaryylipiperidiinien ja -heteroaryylipiperatsiinien valmistamiseksi
KR20210057032A (ko) 메틸 6-(2,4-디클로로페닐)-5-[4-[(3s)-1-(3-플루오로프로필)피롤리딘-3-일]옥시페닐]-8,9-디히드로-7h-벤조[7]아눌렌-2-카르복실레이트의 염 및 이의 제조 방법
TW200403224A (en) Novel compounds
CN102822167A (zh) 用于制备利伐沙班的方法及其中间体
US5717102A (en) Indole derivatives as 5-HT1 agonists
SU585811A3 (ru) Способ получени производных бензимидазолинона или их солей
CA2395705C (en) Substituted phenyl-piperazine derivatives, their preparation and use
CZ299774B6 (cs) Nové piperazinové a piperidinové slouceniny, zpusob jejich prípravy a jejich použití
ZA200204970B (en) Phenylpiperazinyl derivatives.
PT101654B (pt) Processo para a obtencao de 3-&lt;&lt;2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil&gt;&gt;-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona
JP2021098744A (ja) 新規な４−ベンゾアゾニン誘導体の製造方法
SA91110352B1 (ar) عملية محسنة لتحضير مشتقات اندولون مستبدلة
JP4221084B2 (ja) 新規なピペラジン化合物
JPH04211652A (ja) ヘキサヒドロベンズ［ｃｄ］インドール
FI67851C (fi) Foerfarande foer framstaellning av nya dopaminagonistiskt verkande benso(4,5)pyrano(2,3c)pyrrolderivat
RU2279431C2 (ru) Производные бензоксазолона, фармацевтическая композиция и способы лечения
JPH0657709B2 (ja) モルホリン誘導体、その製造方法およびそれを含有する医薬組成物
US3293251A (en) Rearrangement process for j,b-diaza- bicyclo-(j,z,i)-octane derivatives
JP5137824B2 (ja) 所望により放射性標識したイマチニブの製造のための方法および中間体
SU984404A3 (ru) Способ получени циклоалифатических кетоаминов или их солей
KR20070073878A (ko) 아리피프라졸 제조를 위해 유용한 신규 중간체와 신규중간체 및 아리피프라졸 제조 방법
Voskressensky et al. Reaction of 1-substituted tetrahydro-β-carbolines with activated alkynes-a new original approach to the synthesis of tetrahydroazocino [5, 4-b] indoles
JP2000319242A (ja) 新規置換二量体化合物、これらの製造方法及びこれらを含有する医薬組成物
TW202545936A (zh) 製備苯并二氧雜環或其鹽方法

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 20011031

PC3A Transfer or assignment

Free format text: LABORATORIOS VITA, S.A. ES

Effective date: 20030718

PC3A Transfer or assignment

Free format text: VITA CIENTIFICA ES

Effective date: 20050107

PC4A Transfer of assignment

Owner name: INKE, S. A., ES

Effective date: 20071203