PT101654B - Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona - Google Patents

Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona Download PDF

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Publication number
PT101654B
PT101654B PT101654A PT10165495A PT101654B PT 101654 B PT101654 B PT 101654B PT 101654 A PT101654 A PT 101654A PT 10165495 A PT10165495 A PT 10165495A PT 101654 B PT101654 B PT 101654B
Authority
PT
Portugal
Prior art keywords
tetrahydro
pyrimidin
pyrido
methyl
fluoro
Prior art date
Application number
PT101654A
Other languages
English (en)
Portuguese (pt)
Other versions
PT101654A (pt
Inventor
Pere Dalmases Barjoan
Francisco Marquillas Olondriz
Ana Bosch Rovira
Jose Maria Caldero Ges
Juan Huguet Clotet
Juan Carlos Del Castillo Nieto
Original Assignee
Vita Invest Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Invest Sa filed Critical Vita Invest Sa
Publication of PT101654A publication Critical patent/PT101654A/pt
Publication of PT101654B publication Critical patent/PT101654B/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT101654A 1994-02-11 1995-02-09 Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona PT101654B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09400252A ES2074966B1 (es) 1994-02-11 1994-02-11 Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.

Publications (2)

Publication Number Publication Date
PT101654A PT101654A (pt) 1995-09-12
PT101654B true PT101654B (pt) 2002-01-30

Family

ID=8285178

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101654A PT101654B (pt) 1994-02-11 1995-02-09 Processo para a obtencao de 3-<<2-{4-(6-fluoro-benzo-{d}-isoxazol-3-il)piperidin-1-il}-etil>>-2-metil-6,7,8,9-tetra-hidro-4h-pirido-{1,2-a}pirimidin-4-ona

Country Status (14)

Country Link
KR (1) KR100221108B1 (de)
AT (1) AT405401B (de)
CZ (1) CZ286398B6 (de)
EG (1) EG20877A (de)
ES (1) ES2074966B1 (de)
FI (1) FI110000B (de)
GR (1) GR1002344B (de)
HU (1) HU222110B1 (de)
IS (1) IS1766B (de)
NO (1) NO306022B1 (de)
PL (1) PL181420B1 (de)
PT (1) PT101654B (de)
RU (1) RU2123004C1 (de)
SK (1) SK281752B6 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2101646B1 (es) * 1995-04-12 1998-04-01 Ferrer Int Nuevo compuesto derivado del cromeno.
ES2144355B1 (es) * 1997-12-30 2001-01-01 Ferrer Int Compuestos derivados del cromeno.
DE60009959T2 (de) * 2000-05-05 2005-03-31 Rpg Life Sciences Limited Verfahren zur herstellung von antipsychotischem 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-on
HUP0302874A2 (hu) 2000-08-14 2003-12-29 Teva Pharmaceutical Industries Ltd. Eljárás risperidon előállítására
KR20040034996A (ko) 2002-10-18 2004-04-29 한미약품 주식회사 리스페리돈의 개선된 제조방법
WO2004043923A1 (en) 2002-11-13 2004-05-27 Synthon B.V. Process for making risperidone and intermediates therefor
JP5315336B2 (ja) * 2007-04-19 2013-10-16 又欣 李 精神疾患治療用の新規化合物とその調剤及び使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352811A (en) * 1981-11-12 1982-10-05 Hoechst-Roussel Pharmaceuticals Inc. 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US4980365A (en) * 1987-07-13 1990-12-25 Hoechst-Roussel Pharmaceuticals Inc. N-substituted-5,6-dimethoxy-1,2-benzisoxazole-3-propanamine and related compounds as analgesic and hypotensive agents

Also Published As

Publication number Publication date
ATA24995A (de) 1998-12-15
HU222110B1 (hu) 2003-04-28
SK281752B6 (sk) 2001-07-10
RU95101859A (ru) 1997-03-20
NO950501D0 (no) 1995-02-09
IS4259A (is) 1995-08-12
HUT70169A (en) 1995-09-28
PL307200A1 (en) 1995-08-21
EG20877A (en) 2000-05-31
HU9500418D0 (en) 1995-03-28
ES2074966B1 (es) 1996-06-16
AT405401B (de) 1999-08-25
FI110000B (fi) 2002-11-15
IS1766B (is) 2001-03-15
ES2074966A1 (es) 1995-09-16
KR950032196A (ko) 1995-12-20
FI950579A (fi) 1995-08-12
RU2123004C1 (ru) 1998-12-10
CZ32995A3 (en) 1995-09-13
SK15695A3 (en) 1995-10-11
FI950579A0 (fi) 1995-02-10
GR1002344B (el) 1996-05-24
PL181420B1 (pl) 2001-07-31
NO306022B1 (no) 1999-09-06
CZ286398B6 (en) 2000-04-12
NO950501L (no) 1995-08-14
KR100221108B1 (ko) 1999-09-15
PT101654A (pt) 1995-09-12

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