PT1002794E - Derivados de 4-(aril)(aroloxi)metilpiperidina e sua utilização como inibidores da reabsorção da serotonina e/ou noradrenalina - Google Patents
Derivados de 4-(aril)(aroloxi)metilpiperidina e sua utilização como inibidores da reabsorção da serotonina e/ou noradrenalina Download PDFInfo
- Publication number
- PT1002794E PT1002794E PT99500208T PT99500208T PT1002794E PT 1002794 E PT1002794 E PT 1002794E PT 99500208 T PT99500208 T PT 99500208T PT 99500208 T PT99500208 T PT 99500208T PT 1002794 E PT1002794 E PT 1002794E
- Authority
- PT
- Portugal
- Prior art keywords
- serotonin
- aryloxy
- aryl
- reuptake inhibitors
- methyl piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES009802420A ES2157148B1 (es) | 1998-11-18 | 1998-11-18 | Nuevas piperidinas 4-sustituidas. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1002794E true PT1002794E (pt) | 2009-03-25 |
Family
ID=8305832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99500208T PT1002794E (pt) | 1998-11-18 | 1999-11-10 | Derivados de 4-(aril)(aroloxi)metilpiperidina e sua utilização como inibidores da reabsorção da serotonina e/ou noradrenalina |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1002794B1 (pt) |
| JP (1) | JP4667552B2 (pt) |
| KR (1) | KR100646675B1 (pt) |
| AR (1) | AR028805A1 (pt) |
| AT (1) | ATE422199T1 (pt) |
| AU (1) | AU757177B2 (pt) |
| BR (1) | BR9905634B1 (pt) |
| CA (1) | CA2288533C (pt) |
| CY (1) | CY1108955T1 (pt) |
| CZ (1) | CZ296053B6 (pt) |
| DE (1) | DE69940378D1 (pt) |
| DK (1) | DK1002794T3 (pt) |
| ES (2) | ES2157148B1 (pt) |
| HR (1) | HRP990354B1 (pt) |
| HU (1) | HU227558B1 (pt) |
| IL (1) | IL132862A0 (pt) |
| NO (1) | NO314401B1 (pt) |
| PL (1) | PL196329B1 (pt) |
| PT (1) | PT1002794E (pt) |
| RU (1) | RU2232753C2 (pt) |
| TR (1) | TR199902839A2 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003101443A1 (en) * | 2002-05-30 | 2003-12-11 | Head Explorer A/S | The use of milnacipran for the treatment of tension-type headache |
| UA77536C2 (en) * | 2002-07-03 | 2006-12-15 | Lundbeck & Co As H | Secondary aminoaniline piperidines as mch1 antagonists and their use |
| EP1735302B1 (en) | 2004-02-27 | 2010-06-16 | Eli Lilly And Company | 4-amino-piperidine derivatives as monoamine uptake inhibitors |
| CN1968932A (zh) | 2004-06-18 | 2007-05-23 | 惠氏公司 | 制备6－烷基－5－芳基磺酰基－二氢菲啶的方法 |
| EP1854785A1 (en) * | 2006-05-12 | 2007-11-14 | Faes Farma, S.A. | 4-[(3-fluorophenoxy)phenylmethyl]piperidine methanesulfonate: uses, process of synthesis and pharmaceutical compositions |
| CN101506164A (zh) * | 2006-08-23 | 2009-08-12 | 辉瑞产品公司 | 哌啶衍生物 |
| DK2358674T3 (da) * | 2008-11-14 | 2013-04-08 | Theravance Inc | Fremgangsmåde til fremstilling af 4-[2-(2-fluorphenoxymethyl)phenyl]piperidinforbindelser |
| WO2010120910A1 (en) * | 2009-04-15 | 2010-10-21 | Theravance, Inc. | 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds |
| WO2011147780A1 (en) | 2010-05-24 | 2011-12-01 | Faes Farma, S.A. | Flufenoxine derivatives for the treatment and prevention of amiloyd pathologies |
| EP2390248A1 (en) | 2010-05-24 | 2011-11-30 | Faes Farma, S.A. | Flufenoxine derivatives for the treatment and prevention of amiloyd pathologies |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1203149A (en) * | 1968-06-10 | 1970-08-26 | Ici Ltd | Piperidine derivatives |
| JPH0615529B2 (ja) * | 1985-04-01 | 1994-03-02 | エーザイ株式会社 | 新規ピペリジン誘導体 |
| JPH0840999A (ja) * | 1994-08-04 | 1996-02-13 | Yamanouchi Pharmaceut Co Ltd | フルオロインダン誘導体 |
| CO5150201A1 (es) * | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
-
1998
- 1998-11-18 ES ES009802420A patent/ES2157148B1/es not_active Expired - Fee Related
-
1999
- 1999-11-04 CA CA002288533A patent/CA2288533C/en not_active Expired - Fee Related
- 1999-11-08 HU HU9904086A patent/HU227558B1/hu not_active IP Right Cessation
- 1999-11-09 AR ARP990105657A patent/AR028805A1/es active IP Right Grant
- 1999-11-10 DK DK99500208T patent/DK1002794T3/da active
- 1999-11-10 CZ CZ19993995A patent/CZ296053B6/cs not_active IP Right Cessation
- 1999-11-10 PT PT99500208T patent/PT1002794E/pt unknown
- 1999-11-10 IL IL13286299A patent/IL132862A0/xx not_active IP Right Cessation
- 1999-11-10 AT AT99500208T patent/ATE422199T1/de active
- 1999-11-10 EP EP99500208A patent/EP1002794B1/en not_active Expired - Lifetime
- 1999-11-10 ES ES99500208T patent/ES2323742T3/es not_active Expired - Lifetime
- 1999-11-10 DE DE69940378T patent/DE69940378D1/de not_active Expired - Lifetime
- 1999-11-11 AU AU59366/99A patent/AU757177B2/en not_active Ceased
- 1999-11-16 HR HR990354A patent/HRP990354B1/xx not_active IP Right Cessation
- 1999-11-17 RU RU99124412/04A patent/RU2232753C2/ru not_active IP Right Cessation
- 1999-11-17 TR TR1999/02839A patent/TR199902839A2/xx unknown
- 1999-11-17 KR KR1019990051053A patent/KR100646675B1/ko not_active IP Right Cessation
- 1999-11-17 NO NO19995643A patent/NO314401B1/no not_active IP Right Cessation
- 1999-11-17 PL PL336607A patent/PL196329B1/pl not_active IP Right Cessation
- 1999-11-17 BR BRPI9905634-8A patent/BR9905634B1/pt not_active IP Right Cessation
- 1999-11-18 JP JP32888599A patent/JP4667552B2/ja not_active Expired - Fee Related
-
2009
- 2009-04-02 CY CY20091100388T patent/CY1108955T1/el unknown
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