DK1002794T3 - 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer - Google Patents

4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer

Info

Publication number
DK1002794T3
DK1002794T3 DK99500208T DK99500208T DK1002794T3 DK 1002794 T3 DK1002794 T3 DK 1002794T3 DK 99500208 T DK99500208 T DK 99500208T DK 99500208 T DK99500208 T DK 99500208T DK 1002794 T3 DK1002794 T3 DK 1002794T3
Authority
DK
Denmark
Prior art keywords
serotonin
aryloxy
aryl
reuptake inhibitors
norepinephrine reuptake
Prior art date
Application number
DK99500208T
Other languages
English (en)
Inventor
Venero Aurelio Orjales
Avello Antonio Toledo
Duran Carmen Pumar
Original Assignee
Faes Fabrica Espanola De Produ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faes Fabrica Espanola De Produ filed Critical Faes Fabrica Espanola De Produ
Application granted granted Critical
Publication of DK1002794T3 publication Critical patent/DK1002794T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99500208T 1998-11-18 1999-11-10 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer DK1002794T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009802420A ES2157148B1 (es) 1998-11-18 1998-11-18 Nuevas piperidinas 4-sustituidas.

Publications (1)

Publication Number Publication Date
DK1002794T3 true DK1002794T3 (da) 2009-04-14

Family

ID=8305832

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99500208T DK1002794T3 (da) 1998-11-18 1999-11-10 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer

Country Status (21)

Country Link
EP (1) EP1002794B1 (da)
JP (1) JP4667552B2 (da)
KR (1) KR100646675B1 (da)
AR (1) AR028805A1 (da)
AT (1) ATE422199T1 (da)
AU (1) AU757177B2 (da)
BR (1) BR9905634B1 (da)
CA (1) CA2288533C (da)
CY (1) CY1108955T1 (da)
CZ (1) CZ296053B6 (da)
DE (1) DE69940378D1 (da)
DK (1) DK1002794T3 (da)
ES (2) ES2157148B1 (da)
HR (1) HRP990354B1 (da)
HU (1) HU227558B1 (da)
IL (1) IL132862A0 (da)
NO (1) NO314401B1 (da)
PL (1) PL196329B1 (da)
PT (1) PT1002794E (da)
RU (1) RU2232753C2 (da)
TR (1) TR199902839A2 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003101443A1 (en) * 2002-05-30 2003-12-11 Head Explorer A/S The use of milnacipran for the treatment of tension-type headache
UA77536C2 (en) * 2002-07-03 2006-12-15 Lundbeck & Co As H Secondary aminoaniline piperidines as mch1 antagonists and their use
EP1735302B1 (en) 2004-02-27 2010-06-16 Eli Lilly And Company 4-amino-piperidine derivatives as monoamine uptake inhibitors
CN1968932A (zh) 2004-06-18 2007-05-23 惠氏公司 制备6-烷基-5-芳基磺酰基-二氢菲啶的方法
EP1854785A1 (en) * 2006-05-12 2007-11-14 Faes Farma, S.A. 4-[(3-fluorophenoxy)phenylmethyl]piperidine methanesulfonate: uses, process of synthesis and pharmaceutical compositions
CN101506164A (zh) * 2006-08-23 2009-08-12 辉瑞产品公司 哌啶衍生物
DK2358674T3 (da) * 2008-11-14 2013-04-08 Theravance Inc Fremgangsmåde til fremstilling af 4-[2-(2-fluorphenoxymethyl)phenyl]piperidinforbindelser
WO2010120910A1 (en) * 2009-04-15 2010-10-21 Theravance, Inc. 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
WO2011147780A1 (en) 2010-05-24 2011-12-01 Faes Farma, S.A. Flufenoxine derivatives for the treatment and prevention of amiloyd pathologies
EP2390248A1 (en) 2010-05-24 2011-11-30 Faes Farma, S.A. Flufenoxine derivatives for the treatment and prevention of amiloyd pathologies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1203149A (en) * 1968-06-10 1970-08-26 Ici Ltd Piperidine derivatives
JPH0615529B2 (ja) * 1985-04-01 1994-03-02 エーザイ株式会社 新規ピペリジン誘導体
JPH0840999A (ja) * 1994-08-04 1996-02-13 Yamanouchi Pharmaceut Co Ltd フルオロインダン誘導体
CO5150201A1 (es) * 1998-09-07 2002-04-29 Hoffmann La Roche Derivados de piperidina

Also Published As

Publication number Publication date
BR9905634B1 (pt) 2012-09-04
EP1002794B1 (en) 2009-02-04
HU227558B1 (en) 2011-08-29
NO995643L (no) 2000-05-19
ATE422199T1 (de) 2009-02-15
IL132862A0 (en) 2001-03-19
EP1002794A1 (en) 2000-05-24
PT1002794E (pt) 2009-03-25
JP2000154176A (ja) 2000-06-06
AU757177B2 (en) 2003-02-06
CA2288533C (en) 2009-01-06
KR20000035525A (ko) 2000-06-26
HRP990354B1 (en) 2008-11-30
DE69940378D1 (de) 2009-03-19
ES2157148A1 (es) 2001-08-01
PL196329B1 (pl) 2007-12-31
ES2157148B1 (es) 2002-03-01
CY1108955T1 (el) 2014-07-02
HUP9904086A2 (hu) 2000-11-28
CA2288533A1 (en) 2000-05-18
AR028805A1 (es) 2003-05-28
TR199902839A3 (tr) 2000-09-21
TR199902839A2 (xx) 2000-09-21
PL336607A1 (en) 2000-05-22
NO314401B1 (no) 2003-03-17
NO995643D0 (no) 1999-11-17
KR100646675B1 (ko) 2006-11-17
BR9905634A (pt) 2000-09-26
ES2323742T3 (es) 2009-07-23
RU2232753C2 (ru) 2004-07-20
CZ399599A3 (cs) 2000-08-16
HUP9904086A3 (en) 2001-11-28
CZ296053B6 (cs) 2005-12-14
JP4667552B2 (ja) 2011-04-13
HRP990354A2 (en) 2000-06-30
HU9904086D0 (en) 2000-01-28
AU5936699A (en) 2000-05-25

Similar Documents

Publication Publication Date Title
NO972816L (no) Farmasöytisk blanding omfattende mirtazapin og én eller flere selektive serotonin-gjenopptaks-inhibitorer
NO20013452D0 (no) Benzoheterocykler og deres anvendelse som MEK-inhibitorer
NO20021659D0 (no) Biaryleterderivater nyttige som monoamin reopptaksinhibitorer
NO20032830L (no) Tetrahydropyridinderivater, fremstilling derav og anvendelse som celleproliferasjonsinhibitorer
NO20044095L (no) 5-fenyltiazolderivater og anvendelse som P13 kinaseinhibitorer
NO20034187D0 (no) Nye spirotricykliske derivater og anvendelse derav som fosfodiesterase-7 inhibitorer
NO20034307L (no) Cyklopropylindol-derivater som selektive serotonin- gjenopptaksinhibitorer
NO20002486L (no) Sykliske aminderivater og deres anvendelse som legemidler
NO20014702L (no) Diarylderivater og deres anvendelse som medikamenter
NO996491L (no) 4-brom- eller 4-iod-fenylaminobenzhydroksamsyre-derivater og deres anvendelse som MEK-inhibitorer
NO20012688D0 (no) Benzamidderivater og anvendelse derav som APOB-100 sekresjonsinhibitorer
DK1454901T3 (da) Farmaceutiske sammensætninger omfattende tachykininantagonister og en serotoningenoptagelseshæmmer
NO20006029L (no) Pyrazolinderivater, deres fremstilling og anvendelse som legemidler
NO20014135D0 (no) Nye sulfonamidforbindelser og deres anvendelse
NO20016406L (no) Höyselektive reopptaksinhibitorer for norepinefrin
NO20011503D0 (no) Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, deres fremstilling og anvendelse som anorektiske legemidler
NO20005146D0 (no) Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
DK1002794T3 (da) 4-(aryl)(aryloxy)methylpiperidinderivater og anvendelse deraf som serotonin og/eller noradrenalingenoptagelsesinhibitorer
NO996115D0 (no) Azetidinylpropylpiperidin-derivater, intermediater og anvendelse som tachykinin-antagonister
DK0602028T3 (da) Aromatiske sulfonamidderivater, deres anvendelse som enzyminhibitorer og farmaceutiske præparater me d indhold deraf
DK1149094T3 (da) 4-(aminoalkoxy)-benzofuraner som N-myristoyltransferase-inhibitorer
NO994510D0 (no) Substituerte isokinolin-derivater og deres anvendelse som antikonvulsanter
NO20022590L (no) Nye tri-substituerte fenylderivater og analoge
DK1587788T3 (da) 2,7-substituerede indoler og anvendelsen deraf som 5-HT6-modulatorer
DK0839146T3 (da) Piperazinderivater og deres anvendelse som 5-HT1A-antagonister