ATE365723T1 - Il-5 hemmende 6-uracilderivate - Google Patents
Il-5 hemmende 6-uracilderivateInfo
- Publication number
- ATE365723T1 ATE365723T1 AT99965509T AT99965509T ATE365723T1 AT E365723 T1 ATE365723 T1 AT E365723T1 AT 99965509 T AT99965509 T AT 99965509T AT 99965509 T AT99965509 T AT 99965509T AT E365723 T1 ATE365723 T1 AT E365723T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibiting
- uracil derivatives
- uracil
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98204336 | 1998-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE365723T1 true ATE365723T1 (de) | 2007-07-15 |
Family
ID=8234494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99965509T ATE365723T1 (de) | 1998-12-18 | 1999-12-16 | Il-5 hemmende 6-uracilderivate |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6803364B1 (de) |
| EP (1) | EP1140873B1 (de) |
| JP (1) | JP2002533331A (de) |
| KR (1) | KR100635721B1 (de) |
| CN (1) | CN100343239C (de) |
| AR (1) | AR021887A1 (de) |
| AT (1) | ATE365723T1 (de) |
| AU (1) | AU773780B2 (de) |
| BG (1) | BG105602A (de) |
| BR (1) | BR9916366A (de) |
| CA (1) | CA2354511A1 (de) |
| CO (1) | CO5150147A1 (de) |
| CZ (1) | CZ20012062A3 (de) |
| DE (1) | DE69936396T2 (de) |
| DK (1) | DK1140873T3 (de) |
| EA (1) | EA004806B1 (de) |
| EE (1) | EE200100320A (de) |
| ES (1) | ES2289835T3 (de) |
| HK (1) | HK1042491A1 (de) |
| HR (1) | HRP20010455A2 (de) |
| HU (1) | HUP0104641A3 (de) |
| ID (1) | ID28880A (de) |
| IL (1) | IL143766A (de) |
| MY (1) | MY125808A (de) |
| NO (1) | NO319814B1 (de) |
| NZ (1) | NZ512748A (de) |
| PL (1) | PL198205B1 (de) |
| PT (1) | PT1140873E (de) |
| SA (1) | SA00201030B1 (de) |
| SK (1) | SK8152001A3 (de) |
| TR (1) | TR200101729T2 (de) |
| TW (1) | TWI249530B (de) |
| UA (1) | UA73107C2 (de) |
| WO (1) | WO2000037451A1 (de) |
| ZA (1) | ZA200104942B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8466096B2 (en) * | 2007-04-26 | 2013-06-18 | Afton Chemical Corporation | 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions |
| RU2523651C2 (ru) * | 2012-05-22 | 2014-07-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Владивостокский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ВГМУ Минздравсоцразвития России) | Способ дифференцированного контроля базисного противовоспалительного лечения бронхиальной астмы у детей и подростков |
| RU2506045C1 (ru) * | 2012-09-05 | 2014-02-10 | Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения РАМН | Способ прогнозирования достижения контроля бронхиальной астмы |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2149645A1 (de) | 1970-10-07 | 1972-09-14 | Pfizer | 2-Phenyl-as-triazin-3.5-(2H,4H)-dione und die Verwendung dieser Verbindungen zur Bekaempfung der Coccidiose |
| US3912723A (en) | 1971-03-29 | 1975-10-14 | Pfizer | 2-Phenyl-as-triazine-3,5(2H,4H)diones |
| US3883528A (en) | 1974-04-19 | 1975-05-13 | Pfizer | Preparation of 2(aryl)-as-triazine-3,5(2H,4H)-dione coccidiostats |
| CA1244024A (en) | 1984-08-01 | 1988-11-01 | Gustaaf M. Boeckx | .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES |
| US4631278A (en) | 1984-08-01 | 1986-12-23 | Janssen Pharmaceutica N.V. | Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor |
| GB8602342D0 (en) | 1986-01-30 | 1986-03-05 | Janssen Pharmaceutica Nv | 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones |
| CA1331757C (en) | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| DE4120138A1 (de) | 1991-06-19 | 1992-12-24 | Bayer Ag | Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung |
| EP0476439A1 (de) | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
| TW263495B (de) | 1992-12-23 | 1995-11-21 | Celltech Ltd | |
| GB9304920D0 (en) | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
| TW403741B (en) | 1993-10-15 | 2000-09-01 | Takeda Chemical Industries Ltd | Triazine derivative, production and use thereof |
| TW332201B (en) | 1995-04-06 | 1998-05-21 | Janssen Pharmaceutica Nv | 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives |
| EP0737672B1 (de) | 1995-04-14 | 2001-10-04 | Takeda Schering-Plough Animal Health K.K. | Verfahren zur Herstellung von Triazinderivate |
| EP0831088B1 (de) | 1996-08-30 | 2002-11-27 | Takeda Schering-Plough Animal Health K.K. | 1,2,4-Triazin-3,5-Dionderivate als Anticoccidiosemittel |
| ID24224A (id) | 1997-07-10 | 2000-07-13 | Janssen Pharmaceutica Nv | Turunan-turunan 6-azaurasil sebagai inhibitor il-5 |
| CA2294145A1 (en) * | 1997-07-10 | 1999-01-21 | Janssen Pharmaceutica N.V. | Il-5 inhibiting 6-azauracil derivatives |
-
1999
- 1999-12-16 WO PCT/EP1999/010169 patent/WO2000037451A1/en active IP Right Grant
- 1999-12-16 US US09/868,384 patent/US6803364B1/en not_active Expired - Fee Related
- 1999-12-16 CN CNB998146110A patent/CN100343239C/zh not_active Expired - Fee Related
- 1999-12-16 HU HU0104641A patent/HUP0104641A3/hu unknown
- 1999-12-16 JP JP2000589523A patent/JP2002533331A/ja not_active Withdrawn
- 1999-12-16 SK SK815-2001A patent/SK8152001A3/sk unknown
- 1999-12-16 EA EA200100677A patent/EA004806B1/ru not_active IP Right Cessation
- 1999-12-16 DE DE69936396T patent/DE69936396T2/de not_active Expired - Fee Related
- 1999-12-16 KR KR1020017006666A patent/KR100635721B1/ko not_active IP Right Cessation
- 1999-12-16 CA CA002354511A patent/CA2354511A1/en not_active Abandoned
- 1999-12-16 BR BR9916366-7A patent/BR9916366A/pt not_active Application Discontinuation
- 1999-12-16 CZ CZ20012062A patent/CZ20012062A3/cs unknown
- 1999-12-16 AT AT99965509T patent/ATE365723T1/de not_active IP Right Cessation
- 1999-12-16 NZ NZ512748A patent/NZ512748A/en unknown
- 1999-12-16 UA UA2001075132A patent/UA73107C2/uk unknown
- 1999-12-16 AU AU21001/00A patent/AU773780B2/en not_active Ceased
- 1999-12-16 IL IL14376699A patent/IL143766A/xx not_active IP Right Cessation
- 1999-12-16 DK DK99965509T patent/DK1140873T3/da active
- 1999-12-16 EE EEP200100320A patent/EE200100320A/xx unknown
- 1999-12-16 ID IDW00200101295A patent/ID28880A/id unknown
- 1999-12-16 PL PL349526A patent/PL198205B1/pl not_active IP Right Cessation
- 1999-12-16 EP EP99965509A patent/EP1140873B1/de not_active Expired - Lifetime
- 1999-12-16 PT PT99965509T patent/PT1140873E/pt unknown
- 1999-12-16 TR TR2001/01729T patent/TR200101729T2/xx unknown
- 1999-12-16 ES ES99965509T patent/ES2289835T3/es not_active Expired - Lifetime
- 1999-12-17 CO CO99079022A patent/CO5150147A1/es unknown
- 1999-12-17 TW TW088122197A patent/TWI249530B/zh not_active IP Right Cessation
- 1999-12-17 AR ARP990106512A patent/AR021887A1/es not_active Application Discontinuation
- 1999-12-17 MY MYPI99005536A patent/MY125808A/en unknown
-
2000
- 2000-03-05 SA SA00201030A patent/SA00201030B1/ar unknown
-
2001
- 2001-06-14 BG BG105602A patent/BG105602A/xx unknown
- 2001-06-15 HR HR20010455A patent/HRP20010455A2/hr not_active Application Discontinuation
- 2001-06-15 NO NO20012987A patent/NO319814B1/no unknown
- 2001-06-15 ZA ZA200104942A patent/ZA200104942B/en unknown
-
2002
- 2002-06-03 HK HK02104206.0A patent/HK1042491A1/zh unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1140873 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |