DK1115716T3 - 2-phenylpyran-4-on-derivater - Google Patents

2-phenylpyran-4-on-derivater

Info

Publication number
DK1115716T3
DK1115716T3 DK99947372T DK99947372T DK1115716T3 DK 1115716 T3 DK1115716 T3 DK 1115716T3 DK 99947372 T DK99947372 T DK 99947372T DK 99947372 T DK99947372 T DK 99947372T DK 1115716 T3 DK1115716 T3 DK 1115716T3
Authority
DK
Denmark
Prior art keywords
phenylpyran
derivatives
Prior art date
Application number
DK99947372T
Other languages
English (en)
Inventor
Crespo M Isabel Crespo
Mayorga Juan Miguel Jimenez
Duran Carles Puig
Pueyo Lidia Soca
Original Assignee
Almirall Prodesfarma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9802011A external-priority patent/ES2154561B1/es
Priority claimed from ES009900619A external-priority patent/ES2168895A1/es
Application filed by Almirall Prodesfarma Ag filed Critical Almirall Prodesfarma Ag
Application granted granted Critical
Publication of DK1115716T3 publication Critical patent/DK1115716T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/24Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
DK99947372T 1998-09-25 1999-09-16 2-phenylpyran-4-on-derivater DK1115716T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9802011A ES2154561B1 (es) 1998-09-25 1998-09-25 Derivados de 2-fenilpiran-4-ona.
ES009900619A ES2168895A1 (es) 1999-03-26 1999-03-26 Derivados de 2-fenilpiran-4-ona.
PCT/EP1999/006873 WO2000018753A1 (en) 1998-09-25 1999-09-16 2-phenylpyran-4-one derivatives

Publications (1)

Publication Number Publication Date
DK1115716T3 true DK1115716T3 (da) 2003-02-24

Family

ID=26155180

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99947372T DK1115716T3 (da) 1998-09-25 1999-09-16 2-phenylpyran-4-on-derivater

Country Status (34)

Country Link
US (1) US6518303B2 (da)
EP (1) EP1115716B1 (da)
JP (1) JP4717211B2 (da)
KR (1) KR100806684B1 (da)
CN (1) CN1202104C (da)
AR (1) AR021826A1 (da)
AT (1) ATE230405T1 (da)
AU (1) AU765653B2 (da)
BG (1) BG65308B1 (da)
BR (1) BR9913939A (da)
CA (1) CA2345069C (da)
CO (1) CO5140127A1 (da)
CZ (1) CZ300357B6 (da)
DE (1) DE69904738T2 (da)
DK (1) DK1115716T3 (da)
EE (1) EE04812B1 (da)
EG (1) EG23802A (da)
ES (1) ES2190252T3 (da)
HK (1) HK1034961A1 (da)
HU (1) HUP0104620A3 (da)
ID (1) ID28624A (da)
IL (1) IL142087A0 (da)
MX (1) MXPA01003069A (da)
MY (1) MY121793A (da)
NO (1) NO327987B1 (da)
NZ (1) NZ510625A (da)
PE (1) PE20001067A1 (da)
PL (1) PL346895A1 (da)
RU (1) RU2232158C2 (da)
SI (1) SI1115716T1 (da)
SK (1) SK286471B6 (da)
TR (1) TR200100852T2 (da)
TW (1) TW587079B (da)
WO (1) WO2000018753A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011333A1 (es) * 2000-03-16 2002-01-16 Almirall Prodesfarma Ag Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
ES2213485B1 (es) * 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
ES2214130B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 2-3'-bipiridinas.
ES2214129B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 3-fenilfuran-2-onas.
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
WO2005009342A2 (en) * 2003-07-16 2005-02-03 Pharmacia Corporation Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
US20050107350A1 (en) * 2003-08-22 2005-05-19 Pharmacia Corporation Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
WO2005023189A2 (en) * 2003-09-03 2005-03-17 Pharmacia Corporation Method of cox-2 selective inhibitor and nitric oxide-donating agent
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304728A (en) * 1884-09-09 Maubice hellwig
CH524614A (de) * 1969-12-31 1972-06-30 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3901908A (en) * 1970-12-28 1975-08-26 Ciba Geigy Corp 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles
US4304728A (en) * 1979-04-05 1981-12-08 Lilly Industries Limited 6-Substituted pyranone compounds and their use as pharmaceuticals
ES8104268A1 (es) 1979-04-05 1981-04-01 Lilly Industries Ltd Procedimiento para preparar piranonas 5-sustituidas
JPS5834446B2 (ja) * 1979-05-22 1983-07-27 三省製薬株式会社 消炎剤
JPH0768234B2 (ja) * 1989-12-14 1995-07-26 久光製薬株式会社 コウジ酸エステル誘導体
ES2079068T3 (es) * 1990-06-29 1996-01-01 Upjohn Co 2-amino-6-fenil-4h-piran-4-onas antiateroscleroticas y antitromboticas.
JPH04173391A (ja) * 1990-11-07 1992-06-22 Sanyo Chem Ind Ltd 感熱記録用増感剤および感熱記録用材料
DE4103904C2 (de) * 1991-02-08 1995-06-14 Analyticon Ges Fuer Chemische Neue Arzneimittel aus Gamma-Pyronen, Gamma-Pyridonen sowie Gamma-Thiopyronen
US6048850A (en) 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
CZ134396A3 (en) * 1993-11-19 1996-08-14 Parke Davis & Co Pyrone derivatives as protease inhibitors and antiviral agents
US5521213A (en) * 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5541204A (en) 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
CZ313397A3 (cs) 1995-04-04 1998-03-18 Glaxo Group Limited Imidazo/1,2a/pyridinové deriváty, způsob jejich výroby a farmaceutický prostředek s jejich obsahem
ATE301457T1 (de) * 1995-06-12 2005-08-15 Searle & Co Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor
EP1043317B1 (en) * 1997-11-19 2009-04-15 Kowa Co., Ltd. Pyridazine derivatives and medicaments containing them as active ingredient

Also Published As

Publication number Publication date
BG65308B1 (bg) 2008-01-31
CA2345069C (en) 2009-03-10
ATE230405T1 (de) 2003-01-15
AU6084799A (en) 2000-04-17
CZ300357B6 (cs) 2009-04-29
AU765653B2 (en) 2003-09-25
DE69904738T2 (de) 2003-04-30
NZ510625A (en) 2002-12-20
JP4717211B2 (ja) 2011-07-06
TW587079B (en) 2004-05-11
AR021826A1 (es) 2002-08-07
JP2002525364A (ja) 2002-08-13
NO327987B1 (no) 2009-11-02
HUP0104620A3 (en) 2003-01-28
EE04812B1 (et) 2007-04-16
KR20010075369A (ko) 2001-08-09
SK286471B6 (sk) 2008-11-06
CZ20011058A3 (cs) 2001-08-15
SK3702001A3 (en) 2001-12-03
HUP0104620A2 (hu) 2002-04-29
MY121793A (en) 2006-02-28
IL142087A0 (en) 2002-03-10
MXPA01003069A (es) 2002-07-02
US6518303B2 (en) 2003-02-11
EE200100173A (et) 2002-08-15
CN1202104C (zh) 2005-05-18
WO2000018753A1 (en) 2000-04-06
RU2232158C2 (ru) 2004-07-10
PE20001067A1 (es) 2000-10-23
BR9913939A (pt) 2001-06-12
EG23802A (en) 2007-08-22
ID28624A (id) 2001-06-21
ES2190252T3 (es) 2003-07-16
CO5140127A1 (es) 2002-03-22
NO20011512L (no) 2001-05-25
PL346895A1 (en) 2002-03-11
BG105373A (en) 2001-11-30
TR200100852T2 (tr) 2001-10-22
HK1034961A1 (en) 2001-11-09
CN1324352A (zh) 2001-11-28
EP1115716B1 (en) 2003-01-02
DE69904738D1 (de) 2003-02-06
CA2345069A1 (en) 2000-04-06
NO20011512D0 (no) 2001-03-23
EP1115716A1 (en) 2001-07-18
US20020045644A1 (en) 2002-04-18
SI1115716T1 (en) 2003-06-30
KR100806684B1 (ko) 2008-02-26

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