PL99858B1 - Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego - Google Patents

Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego Download PDF

Info

Publication number
PL99858B1
PL99858B1 PL1975185475A PL18547575A PL99858B1 PL 99858 B1 PL99858 B1 PL 99858B1 PL 1975185475 A PL1975185475 A PL 1975185475A PL 18547575 A PL18547575 A PL 18547575A PL 99858 B1 PL99858 B1 PL 99858B1
Authority
PL
Poland
Prior art keywords
amino
formula
carboxylic acid
trifluoromethylindazole
melting point
Prior art date
Application number
PL1975185475A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL99858B1 publication Critical patent/PL99858B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL1975185475A 1974-12-13 1975-12-11 Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego PL99858B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PL99858B1 true PL99858B1 (pl) 1978-08-31

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1975185475A PL99858B1 (pl) 1974-12-13 1975-12-11 Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego

Country Status (27)

Country Link
US (1) US4051252A (OSRAM)
JP (1) JPS5182266A (OSRAM)
AT (1) AT343653B (OSRAM)
BE (1) BE836528A (OSRAM)
CA (1) CA1059523A (OSRAM)
CH (1) CH622250A5 (OSRAM)
CS (1) CS189731B2 (OSRAM)
DD (1) DD125484A5 (OSRAM)
DE (1) DE2458965C3 (OSRAM)
DK (1) DK137082C (OSRAM)
ES (1) ES443429A1 (OSRAM)
FI (1) FI753493A7 (OSRAM)
FR (1) FR2293928A1 (OSRAM)
GB (1) GB1490306A (OSRAM)
HK (1) HK52580A (OSRAM)
HU (1) HU173557B (OSRAM)
IE (1) IE42208B1 (OSRAM)
IL (1) IL48642A (OSRAM)
KE (1) KE3078A (OSRAM)
LU (1) LU73993A1 (OSRAM)
NL (1) NL7514521A (OSRAM)
NO (1) NO145382C (OSRAM)
PL (1) PL99858B1 (OSRAM)
SE (1) SE419645B (OSRAM)
SU (1) SU604487A3 (OSRAM)
YU (1) YU315275A (OSRAM)
ZA (1) ZA757777B (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
KR20030030005A (ko) * 2000-09-15 2003-04-16 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제 억제제로서 유용한 피라졸 화합물
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
EP1698627A1 (en) * 2000-09-15 2006-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
CN1926132B (zh) * 2000-09-15 2010-12-29 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的吡唑化合物
EP1345927B1 (en) 2000-12-21 2006-05-17 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
DE60238999D1 (de) 2001-09-26 2011-03-03 Pfizer Italia Srl Aminoindazolderivate mit kinaseinhibierender wirkung, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
PL372198A1 (en) * 2002-02-06 2005-07-11 Vertex Pharmaceuticals Incorporated Heteroaryl compounds useful as inhibitors of gsk-3
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
WO2003078427A1 (en) 2002-03-15 2003-09-25 Vertex Pharmaceuticals, Inc. Azolylaminoazines as inhibitors of protein kinases
BR0311291A (pt) 2002-05-17 2005-03-29 Pharmacia Italia Spa Derivados de aminoindazol ativos como inibidores da cinase, processo para sua preparação e composições farmacêuticas compreendendo os mesmos
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
KR20050032105A (ko) 2002-08-02 2005-04-06 버텍스 파마슈티칼스 인코포레이티드 Ｇｓｋ-3의 억제제로서 유용한 피라졸 조성물
WO2004041285A1 (en) * 2002-10-31 2004-05-21 Amgen Inc. Antiinflammation agents
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
CA2548172A1 (en) * 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
DE102004005172A1 (de) 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
ATE542814T1 (de) 2005-08-18 2012-02-15 Vertex Pharma Pyrazinkinaseinhibitoren
WO2007056163A2 (en) 2005-11-03 2007-05-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
KR101118932B1 (ko) * 2006-04-14 2012-02-27 아보트 러보러터리즈 바닐로이드 서브타입 1(ｖｒ1) 수용체를 억제하는 인다졸릴우레아의 제조방법
WO2008057940A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
DE602007007985D1 (de) 2006-12-19 2010-09-02 Vertex Pharma Als inhibitoren von proteinkinasen geeignete aminopyrimidine
CA2679884A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
RU2009137390A (ru) 2007-03-09 2011-04-20 Вертекс Фармасьютикалз Инкорпорейтед (Us) Аминопиримидины, пригодные в качестве ингибиторов протеинкиназ
AU2008226461A1 (en) 2007-03-09 2008-09-18 Vertex Pharmaceuticals Incorporated Aminopyridines useful as inhibitors of protein kinases
EP2146982A2 (en) 2007-04-13 2010-01-27 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
EP2155730A2 (en) * 2007-05-02 2010-02-24 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
EP2152694A2 (en) * 2007-05-02 2010-02-17 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
CA2694381A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
CN101687852A (zh) * 2007-05-24 2010-03-31 沃泰克斯药物股份有限公司 可用作激酶抑制剂的噻唑类和吡唑类化合物
CN101790532B (zh) 2007-07-31 2013-11-20 沃泰克斯药物股份有限公司 5-氟-1H-吡唑并[3，4-b]吡啶-3-胺及其衍生物的制备方法
JP2012501971A (ja) * 2008-09-03 2012-01-26 バーテックス ファーマシューティカルズ インコーポレイテッド 共結晶および共結晶を含む薬学的処方物
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
SI2890684T1 (en) 2012-07-24 2018-06-29 Bial-Portela & Ca, S.A. THE CLOTHING MACHINE AND THEIR USE AS ENCLOSURE INHIBITORS
EP2882712A2 (en) * 2012-07-27 2015-06-17 BIAL - Portela & Cª S.A. Process for the synthesis of substituted urea compounds
LT3024825T (lt) 2013-07-24 2017-12-11 Bial - Portela & C, S.A. Imidazolo karboksamidai ir jų panaudojimas kaip faah inhibitorių

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3274203A (en) * 1963-05-31 1966-09-20 Du Pont 1-carbamyl and thiocarbamyl-3-amino-4-nonsubstituted and substituted pyrazoles
NL6707299A (OSRAM) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
IE42208L (en) 1976-06-13
FR2293928A1 (fr) 1976-07-09
DD125484A5 (OSRAM) 1977-04-20
BE836528A (fr) 1976-06-11
KE3078A (en) 1980-10-03
ATA939775A (de) 1977-10-15
HU173557B (hu) 1979-06-28
IL48642A0 (en) 1976-02-29
AT343653B (de) 1978-06-12
DE2458965A1 (de) 1976-06-16
SE419645B (sv) 1981-08-17
SE7513990L (sv) 1976-06-14
NO145382C (no) 1982-03-10
DK137082C (da) 1978-06-19
DE2458965C3 (de) 1979-10-11
JPS5182266A (en) 1976-07-19
GB1490306A (en) 1977-11-02
LU73993A1 (OSRAM) 1976-11-11
DE2458965B2 (de) 1979-02-22
DK567275A (da) 1976-06-14
CA1059523A (en) 1979-07-31
ES443429A1 (es) 1977-04-16
FR2293928B1 (OSRAM) 1979-09-21
CH622250A5 (OSRAM) 1981-03-31
YU315275A (en) 1982-02-28
IL48642A (en) 1979-12-30
NO145382B (no) 1981-11-30
US4051252A (en) 1977-09-27
CS189731B2 (en) 1979-04-30
DK137082B (da) 1978-01-16
ZA757777B (en) 1976-11-24
SU604487A3 (ru) 1978-04-25
HK52580A (en) 1980-09-26
IE42208B1 (en) 1980-06-18
NL7514521A (nl) 1976-06-15
NO754024L (OSRAM) 1976-06-15
FI753493A7 (OSRAM) 1976-06-14
AU8717075A (en) 1977-06-09

Similar Documents

Publication Publication Date Title
PL99858B1 (pl) Sposob wytwarzania nowych pochodnych kwasu 3-aminoindazolokarboksylowego
US4880810A (en) Quinazolinediones and pyridopyrimidinediones
US4296126A (en) 3-Aryloxy-3-aryl-propaneamines and their method of use
CA2063172A1 (en) 4-aryl-thiazole or imidazole derivatives
US4346097A (en) Method for treating convulsions with pyrazole-4-carboxamide derivatives
US3988345A (en) Imidazoline derivatives and the preparation thereof
US4115647A (en) Amidinoureas
PL142626B1 (en) Method of obtaining novel derivatives of aminoguanidine
PL80614B1 (OSRAM)
Auzzi et al. 2-Phenylpyrazolo [1, 5-a] pyrimidin-7-ones. A new class of nonsteroidal antiinflammatory drugs devoid of ulcerogenic activity
IE911406A1 (en) New pyridazines
DE2724485A1 (de) Benzamid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
US3673188A (en) Heterocyclic amidoximes
PL76889B1 (OSRAM)
GB1593822A (en) Manufacture of pyridones
US4154734A (en) Amides of 4-hydroxy-6H-thieno[2,3-b]thiopyran-5-carboxylic acid-7,7-dioxide
US4797403A (en) Quinazolinediones and pyridopyrimidinediones
Martin et al. Sulfanilamidoquinazolines
US3953461A (en) Amino derivatives of thiazolo[5,4-b]pyridine-6-carboxylic acids and esters
US3970661A (en) 2-Amino, 5-carbamoyl pyridine compounds
PL143303B1 (en) Method of obtaining novel amidino-derivatives of 2-substituted 4-phenylimidazolone
US3398155A (en) 2, 6-dichloro-isonicotinamide derivatives and a method for their preparation
HU196400B (en) Process for producing 3-(acylaminomethyl)-imidazo square brackets open 1,2-a square brackets closed pyridine derivatives and pharmaceutics comprising these compounds
EP0628549A1 (en) New 1-phenylmethyl benzimidazole piperazine derivatives
US3970663A (en) Certain amino-nicotinamide derivatives