PL92086B1 - - Google Patents

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Publication number
PL92086B1
PL92086B1 PL1974175144A PL17514474A PL92086B1 PL 92086 B1 PL92086 B1 PL 92086B1 PL 1974175144 A PL1974175144 A PL 1974175144A PL 17514474 A PL17514474 A PL 17514474A PL 92086 B1 PL92086 B1 PL 92086B1
Authority
PL
Poland
Prior art keywords
acid
formula
compounds
hydrochloride
reaction
Prior art date
Application number
PL1974175144A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL92086B1 publication Critical patent/PL92086B1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL1974175144A 1973-10-27 1974-10-26 PL92086B1 (enEXAMPLES)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
PL92086B1 true PL92086B1 (enEXAMPLES) 1977-03-31

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1974175143A PL92052B1 (enEXAMPLES) 1973-10-27 1974-10-26
PL1974175142A PL92053B1 (enEXAMPLES) 1973-10-27 1974-10-26
PL1974175144A PL92086B1 (enEXAMPLES) 1973-10-27 1974-10-26

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL1974175143A PL92052B1 (enEXAMPLES) 1973-10-27 1974-10-26
PL1974175142A PL92053B1 (enEXAMPLES) 1973-10-27 1974-10-26

Country Status (27)

Country Link
US (1) US3981874A (enEXAMPLES)
JP (1) JPS5738590B2 (enEXAMPLES)
AT (6) AT335633B (enEXAMPLES)
BE (1) BE821505A (enEXAMPLES)
BG (3) BG27902A3 (enEXAMPLES)
CA (1) CA1056377A (enEXAMPLES)
CH (6) CH609046A5 (enEXAMPLES)
CS (3) CS171195B2 (enEXAMPLES)
DD (1) DD115909A5 (enEXAMPLES)
DE (1) DE2354002A1 (enEXAMPLES)
DK (1) DK138325C (enEXAMPLES)
ES (6) ES431055A1 (enEXAMPLES)
FI (1) FI62079C (enEXAMPLES)
FR (1) FR2248838B1 (enEXAMPLES)
GB (1) GB1482552A (enEXAMPLES)
HU (1) HU176479B (enEXAMPLES)
IE (1) IE41528B1 (enEXAMPLES)
IL (1) IL45938A (enEXAMPLES)
NL (1) NL7413980A (enEXAMPLES)
NO (1) NO140859C (enEXAMPLES)
PH (1) PH11894A (enEXAMPLES)
PL (3) PL92052B1 (enEXAMPLES)
RO (5) RO65656A (enEXAMPLES)
SE (1) SE422791B (enEXAMPLES)
SU (6) SU510999A3 (enEXAMPLES)
YU (5) YU36950B (enEXAMPLES)
ZA (1) ZA746790B (enEXAMPLES)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
US8859580B2 (en) 2007-11-16 2014-10-14 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009100872A1 (en) * 2008-02-12 2009-08-20 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
EP2300461B1 (en) 2008-05-01 2013-04-17 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
KR20110050459A (ko) 2008-07-25 2011-05-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166801B2 (enEXAMPLES) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
AT336202B (de) 1977-04-25
CH609686A5 (enEXAMPLES) 1979-03-15
FI62079C (fi) 1982-11-10
ES431058A1 (es) 1976-10-16
ATA828574A (de) 1976-07-15
ES431057A1 (es) 1976-10-16
RO65656A (ro) 1980-06-15
DE2354002A1 (de) 1975-05-07
AT335631B (de) 1977-03-25
FR2248838B1 (enEXAMPLES) 1977-11-04
YU36951B (en) 1984-08-31
SU578870A3 (ru) 1977-10-30
ES431059A1 (es) 1976-10-16
YU36519B (en) 1984-02-29
IE41528L (en) 1975-04-27
JPS5738590B2 (enEXAMPLES) 1982-08-16
RO65655A (ro) 1980-06-15
ES431055A1 (es) 1976-10-16
IL45938A0 (en) 1974-12-31
AT335634B (de) 1977-03-25
ATA828974A (de) 1976-08-15
YU36952B (en) 1984-08-31
DD115909A5 (enEXAMPLES) 1975-10-20
SU508193A3 (ru) 1976-03-25
SU511005A3 (ru) 1976-04-15
GB1482552A (en) 1977-08-10
AT335633B (de) 1977-03-25
AT335076B (de) 1977-02-25
BG27902A3 (bg) 1980-01-15
SE422791B (sv) 1982-03-29
YU285374A (en) 1982-06-18
NO140859B (no) 1979-08-20
PH11894A (en) 1978-08-29
YU285474A (en) 1982-06-18
ZA746790B (en) 1976-06-30
PL92053B1 (enEXAMPLES) 1977-03-31
NO743845L (enEXAMPLES) 1975-05-26
SU508192A3 (ru) 1976-03-25
IE41528B1 (en) 1980-01-30
DK559874A (enEXAMPLES) 1975-06-23
YU36950B (en) 1984-08-31
YU285674A (en) 1982-06-18
DK138325B (da) 1978-08-14
FI62079B (fi) 1982-07-30
ES431056A1 (es) 1976-10-16
ES431054A1 (es) 1976-10-16
AT335632B (de) 1977-03-25
BG27901A3 (bg) 1980-01-15
CH609048A5 (enEXAMPLES) 1979-02-15
HU176479B (en) 1981-03-28
FI314174A7 (enEXAMPLES) 1975-04-28
CA1056377A (en) 1979-06-12
CH609340A5 (enEXAMPLES) 1979-02-28
BE821505A (fr) 1975-04-25
DK138325C (da) 1979-01-22
CS171195B2 (enEXAMPLES) 1976-10-29
ATA828874A (de) 1976-06-15
CS171196B2 (enEXAMPLES) 1976-10-29
SU512707A3 (ru) 1976-04-30
CS171194B2 (enEXAMPLES) 1976-10-29
SE7413485L (enEXAMPLES) 1975-04-28
YU36949B (en) 1984-08-31
BG27903A3 (bg) 1980-01-15
ATA828674A (de) 1976-07-15
RO65657A (ro) 1980-06-15
US3981874A (en) 1976-09-21
FR2248838A1 (enEXAMPLES) 1975-05-23
NO140859C (no) 1979-11-28
JPS5071679A (enEXAMPLES) 1975-06-13
PL92052B1 (enEXAMPLES) 1977-03-31
SU510999A3 (ru) 1976-04-15
RO65659A (ro) 1980-06-15
CH609046A5 (enEXAMPLES) 1979-02-15
CH609047A5 (enEXAMPLES) 1979-02-15
CH609685A5 (enEXAMPLES) 1979-03-15
ATA828774A (de) 1976-07-15
ATA829074A (de) 1976-07-15
NL7413980A (nl) 1975-04-29
YU285274A (en) 1982-02-25
IL45938A (en) 1977-12-30
RO65658A (fr) 1979-07-15
YU285174A (en) 1982-06-18

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