PL2970441T3 - POLIPEPTYDY ZAWIERAJĄCE AGLIKOZYLOWANY Fc - Google Patents
POLIPEPTYDY ZAWIERAJĄCE AGLIKOZYLOWANY FcInfo
- Publication number
- PL2970441T3 PL2970441T3 PL14769541T PL14769541T PL2970441T3 PL 2970441 T3 PL2970441 T3 PL 2970441T3 PL 14769541 T PL14769541 T PL 14769541T PL 14769541 T PL14769541 T PL 14769541T PL 2970441 T3 PL2970441 T3 PL 2970441T3
- Authority
- PL
- Poland
- Prior art keywords
- aglycosylated
- polypeptides containing
- polypeptides
- containing aglycosylated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784669P | 2013-03-14 | 2013-03-14 | |
| EP14769541.5A EP2970441B1 (en) | 2013-03-14 | 2014-03-14 | AGLYCOSYLATED Fc-CONTAINING POLYPEPTIDES |
| PCT/US2014/028913 WO2014153063A1 (en) | 2013-03-14 | 2014-03-14 | AGLYCOSYLATED Fc-CONTAINING POLYPEPTIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2970441T3 true PL2970441T3 (pl) | 2019-09-30 |
Family
ID=50680166
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14722463T PL2970423T3 (pl) | 2013-03-14 | 2014-03-14 | Muteiny interleukiny-2 do ekspansji regulatorowych komórek t |
| PL14769541T PL2970441T3 (pl) | 2013-03-14 | 2014-03-14 | POLIPEPTYDY ZAWIERAJĄCE AGLIKOZYLOWANY Fc |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14722463T PL2970423T3 (pl) | 2013-03-14 | 2014-03-14 | Muteiny interleukiny-2 do ekspansji regulatorowych komórek t |
Country Status (40)
| Country | Link |
|---|---|
| US (8) | US9546203B2 (pl) |
| EP (2) | EP2970441B1 (pl) |
| JP (6) | JP6450365B2 (pl) |
| KR (5) | KR102219124B1 (pl) |
| CN (2) | CN105143253B (pl) |
| AP (1) | AP2015008737A0 (pl) |
| AR (1) | AR095541A1 (pl) |
| AU (2) | AU2014236281B2 (pl) |
| BR (1) | BR112015022440B1 (pl) |
| CA (3) | CA2906708C (pl) |
| CL (2) | CL2015002686A1 (pl) |
| CR (2) | CR20200004A (pl) |
| CY (2) | CY1121767T1 (pl) |
| DK (2) | DK2970423T3 (pl) |
| EA (2) | EA034326B1 (pl) |
| ES (2) | ES2720225T3 (pl) |
| HR (2) | HRP20190970T1 (pl) |
| HU (2) | HUE044321T2 (pl) |
| IL (2) | IL241349B (pl) |
| JO (1) | JO3796B1 (pl) |
| LT (2) | LT2970441T (pl) |
| MA (2) | MA38477B1 (pl) |
| ME (2) | ME03482B (pl) |
| MX (2) | MX366854B (pl) |
| MY (2) | MY172991A (pl) |
| NZ (1) | NZ751148A (pl) |
| PE (1) | PE20151763A1 (pl) |
| PH (1) | PH12015502051A1 (pl) |
| PL (2) | PL2970423T3 (pl) |
| PT (2) | PT2970441T (pl) |
| RS (2) | RS58854B1 (pl) |
| SG (2) | SG11201507574VA (pl) |
| SI (2) | SI2970441T1 (pl) |
| SM (2) | SMT201900301T1 (pl) |
| TN (1) | TN2015000416A1 (pl) |
| TR (2) | TR201910802T4 (pl) |
| TW (3) | TWI784288B (pl) |
| UA (1) | UA119140C2 (pl) |
| UY (2) | UY40090A (pl) |
| WO (2) | WO2014153063A1 (pl) |
Families Citing this family (132)
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| US20190202898A9 (en) * | 2012-04-03 | 2019-07-04 | Novelmed Therapeutics, Inc. | AGLYCOSYLATED ANTI-C3b ANTIBODIES AND USES THEREOF |
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| CN104870474B (zh) * | 2012-10-04 | 2019-03-12 | 诺沃姆德治疗公司 | 用于治疗溶血性疾病的旁路途径特异性抗体 |
| US9546203B2 (en) * | 2013-03-14 | 2017-01-17 | Amgen Inc. | Aglycosylated Fc-containing polypeptides with cysteine substitutions |
| SG11201507416WA (en) | 2013-03-15 | 2015-10-29 | Amgen Inc | Human pac1 antibodies |
| ES2676023T3 (es) | 2013-03-15 | 2018-07-16 | F. Hoffmann-La Roche Ag | Polipéptidos de IL-22 y proteínas de fusión de IL-22 Fc y métodos de uso |
| RS58149B1 (sr) | 2014-02-06 | 2019-02-28 | Hoffmann La Roche | Fuzioni proteini interleukina-2 i njihova upotreba |
| JP6768633B2 (ja) * | 2014-07-21 | 2020-10-14 | デリニア， インコーポレイテッド | 自己免疫疾患を治療するために調節性ｔ細胞を選択的に活性化する分子 |
| ES2807260T3 (es) | 2014-08-11 | 2021-02-22 | Delinia Inc | Variantes de IL-2 modificadas que activan selectivamente las células T reguladoras para el tratamiento de enfermedades autoinmunes |
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| HUE055460T2 (hu) | 2014-12-15 | 2021-11-29 | Univ Washington | Készítmények és módszerek a célzott citokin bejuttatására |
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| EA201792250A1 (ru) * | 2015-04-10 | 2018-05-31 | Эмджен Инк. | Мутеины интерлейкина-2 для роста регуляторных т-клеток |
| TWI744242B (zh) | 2015-07-31 | 2021-11-01 | 德商安美基研究（慕尼黑）公司 | Egfrviii及cd3抗體構築體 |
| EA039859B1 (ru) * | 2015-07-31 | 2022-03-21 | Эмджен Рисерч (Мюник) Гмбх | Биспецифические конструкты антител, связывающие egfrviii и cd3 |
| TWI829617B (zh) | 2015-07-31 | 2024-01-21 | 德商安美基研究（慕尼黑）公司 | Ｆｌｔ３及ｃｄ３抗體構築體 |
| TWI796283B (zh) | 2015-07-31 | 2023-03-21 | 德商安美基研究（慕尼黑）公司 | Ｍｓｌｎ及ｃｄ３抗體構築體 |
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