PL2592072T3 - Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i ich zastosowanie - Google Patents

Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i ich zastosowanie

Info

Publication number
PL2592072T3
PL2592072T3 PL12196174T PL12196174T PL2592072T3 PL 2592072 T3 PL2592072 T3 PL 2592072T3 PL 12196174 T PL12196174 T PL 12196174T PL 12196174 T PL12196174 T PL 12196174T PL 2592072 T3 PL2592072 T3 PL 2592072T3
Authority
PL
Poland
Prior art keywords
protein tyrosine
human protein
tyrosine phosphatase
phosphatase inhibitors
inhibitors
Prior art date
Application number
PL12196174T
Other languages
English (en)
Polish (pl)
Inventor
Jeffrey Lyle Gray
Cynthia Monesa Clark
Kande K.D. Amarasinghe
Mathew Brian Maier
Ryan Nichols
Original Assignee
Aerpio Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aerpio Therapeutics, Inc. filed Critical Aerpio Therapeutics, Inc.
Publication of PL2592072T3 publication Critical patent/PL2592072T3/pl

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
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    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • AIDS & HIV (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PL12196174T 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i ich zastosowanie PL2592072T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81673006P 2006-06-27 2006-06-27
EP07809907.4A EP2041102B1 (en) 2006-06-27 2007-06-27 Human protein tyrosine phosphatase inhibitors and methods of use
EP12196174.2A EP2592072B1 (en) 2006-06-27 2007-06-27 Human protein tyrosine phosphatase inhibitors and their use

Publications (1)

Publication Number Publication Date
PL2592072T3 true PL2592072T3 (pl) 2018-02-28

Family

ID=38704713

Family Applications (3)

Application Number Title Priority Date Filing Date
PL12196174T PL2592072T3 (pl) 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i ich zastosowanie
PL17191765T PL3323815T3 (pl) 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej oraz sposoby zastosowania
PL07809907T PL2041102T3 (pl) 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i sposoby stosowania

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL17191765T PL3323815T3 (pl) 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej oraz sposoby zastosowania
PL07809907T PL2041102T3 (pl) 2006-06-27 2007-06-27 Inhibitory ludzkiej białkowej fosfatazy tyrozynowej i sposoby stosowania

Country Status (20)

Country Link
US (13) US7622593B2 (enExample)
EP (3) EP2041102B1 (enExample)
JP (2) JP5232778B2 (enExample)
KR (1) KR101155365B1 (enExample)
CN (1) CN101506183B (enExample)
AU (1) AU2007265453B2 (enExample)
BR (1) BRPI0713570A2 (enExample)
CA (1) CA2657096C (enExample)
CO (1) CO6150144A2 (enExample)
DK (3) DK2041102T3 (enExample)
ES (3) ES2650598T3 (enExample)
IL (1) IL196128A (enExample)
MX (1) MX2009000288A (enExample)
NZ (1) NZ574407A (enExample)
PL (3) PL2592072T3 (enExample)
PT (3) PT3323815T (enExample)
RU (1) RU2447065C2 (enExample)
SI (1) SI2041102T1 (enExample)
WO (1) WO2008002569A2 (enExample)
ZA (1) ZA200900559B (enExample)

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US7226755B1 (en) * 2002-09-25 2007-06-05 The Procter & Gamble Company HPTPbeta as a target in treatment of angiogenesis mediated disorders
US7507568B2 (en) * 2002-09-25 2009-03-24 The Proctor & Gamble Company Three dimensional coordinates of HPTPbeta
US7973142B2 (en) 2006-04-07 2011-07-05 Warner Chilcott Company Antibodies that bind human protein tyrosine phosphatase beta (HPTPβ)
US7622593B2 (en) 2006-06-27 2009-11-24 The Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US7795444B2 (en) 2006-06-27 2010-09-14 Warner Chilcott Company Human protein tyrosine phosphatase inhibitors and methods of use
US7589212B2 (en) * 2006-06-27 2009-09-15 Procter & Gamble Company Human protein tyrosine phosphatase inhibitors and methods of use
US8846685B2 (en) 2006-06-27 2014-09-30 Aerpio Therapeutics Inc. Human protein tyrosine phosphatase inhibitors and methods of use
AU2016203254B2 (en) * 2009-01-12 2018-09-13 EyePoint Pharmaceuticals, Inc. Methods for treating vascular leak syndrome
RU2014146121A (ru) * 2009-01-12 2015-06-10 Аэрпио Терапьютикс Инк. Способы лечения синдрома сосудистой утечки
AU2014202211B2 (en) * 2009-01-12 2016-06-02 EyePoint Pharmaceuticals, Inc. Methods for treating vascular leak syndrome
US9096555B2 (en) 2009-01-12 2015-08-04 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome
MX2011007420A (es) * 2009-07-06 2011-12-14 Akebia Therapeutics Inc Compuestos, composiciones y metodos para prevenir la metastasis de las celulas cancerigenas.
US8883832B2 (en) 2009-07-06 2014-11-11 Aerpio Therapeutics Inc. Compounds, compositions, and methods for preventing metastasis of cancer cells
PL2496236T4 (pl) 2009-11-06 2015-11-30 Aerpio Therapeutics Inc Inhibitory hydroksylazy prolilowej
JP2013525290A (ja) * 2010-04-15 2013-06-20 ノバルティス アーゲー Ｋｓｐ阻害剤としてのオキサゾールおよびチアゾール化合物
BR112013008452A2 (pt) * 2010-10-07 2016-06-28 Aerpio Therapeutics Inc composição e métodos de tratamento de edema ocular, neovascularização e doenças relacionadas
US20180092883A1 (en) * 2010-10-07 2018-04-05 Aerpio Therapeutics, Inc. Phosphatase inhibitors for treating ocular diseases
CN102408417B (zh) * 2011-09-26 2015-03-11 上海交通大学 2-取代乙烯磺酸酯类化合物及其制备方法和应用
EP3505182A1 (en) 2011-10-13 2019-07-03 Aerpio Therapeutics, Inc. Methods for treating vascular leak syndrome and cancer
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