PL2508521T5 - Dimaleinian związku aminokrotonylowego oraz sposób jego wytwarzania - Google Patents
Dimaleinian związku aminokrotonylowego oraz sposób jego wytwarzaniaInfo
- Publication number
- PL2508521T5 PL2508521T5 PL12155662.5T PL12155662T PL2508521T5 PL 2508521 T5 PL2508521 T5 PL 2508521T5 PL 12155662 T PL12155662 T PL 12155662T PL 2508521 T5 PL2508521 T5 PL 2508521T5
- Authority
- PL
- Poland
- Prior art keywords
- dimaleat
- production
- compound
- amino
- amino crotonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10349113A DE10349113A1 (de) | 2003-10-17 | 2003-10-17 | Verfahren zur Herstellung von Aminocrotonylverbindungen |
EP12155662.5A EP2508521B2 (de) | 2003-10-17 | 2004-10-12 | Dimaleat einer Aminocrotonylverbindung und Verfahren zu ihrer Herstellung |
EP04765927.1A EP1678165B1 (de) | 2003-10-17 | 2004-10-12 | Verfahren zur herstellung von aminocrotonylverbindungen |
Publications (2)
Publication Number | Publication Date |
---|---|
PL2508521T3 PL2508521T3 (pl) | 2016-06-30 |
PL2508521T5 true PL2508521T5 (pl) | 2023-03-27 |
Family
ID=34428508
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04765927T PL1678165T3 (pl) | 2003-10-17 | 2004-10-12 | Sposób wytwarzania związków aminokrotonylowych |
PL12155662.5T PL2508521T5 (pl) | 2003-10-17 | 2004-10-12 | Dimaleinian związku aminokrotonylowego oraz sposób jego wytwarzania |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL04765927T PL1678165T3 (pl) | 2003-10-17 | 2004-10-12 | Sposób wytwarzania związków aminokrotonylowych |
Country Status (35)
Country | Link |
---|---|
US (2) | US20050085495A1 (pl) |
EP (2) | EP1678165B1 (pl) |
JP (2) | JP4594317B2 (pl) |
KR (2) | KR101180752B1 (pl) |
CN (2) | CN101402631A (pl) |
AR (1) | AR046118A1 (pl) |
AU (2) | AU2004281938B2 (pl) |
BR (2) | BR122013033343B8 (pl) |
CA (2) | CA2759063C (pl) |
CY (2) | CY1114866T1 (pl) |
DE (1) | DE10349113A1 (pl) |
DK (2) | DK2508521T4 (pl) |
EA (1) | EA016624B1 (pl) |
EC (1) | ECSP066509A (pl) |
ES (2) | ES2440466T3 (pl) |
HK (1) | HK1095817A1 (pl) |
HR (2) | HRP20160246T4 (pl) |
HU (1) | HUE028254T2 (pl) |
IL (2) | IL174951A (pl) |
ME (1) | ME00341B (pl) |
MX (2) | MXPA06004076A (pl) |
MY (2) | MY155425A (pl) |
NO (2) | NO333971B1 (pl) |
NZ (2) | NZ583049A (pl) |
PE (2) | PE20100267A1 (pl) |
PL (2) | PL1678165T3 (pl) |
PT (2) | PT2508521E (pl) |
RS (3) | RS20060260A (pl) |
SG (1) | SG139743A1 (pl) |
SI (2) | SI1678165T1 (pl) |
TW (2) | TWI373470B (pl) |
UA (2) | UA91401C2 (pl) |
UY (2) | UY28559A1 (pl) |
WO (1) | WO2005037824A2 (pl) |
ZA (1) | ZA200602234B (pl) |
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DE10349113A1 (de) * | 2003-10-17 | 2005-05-12 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Aminocrotonylverbindungen |
KR100832593B1 (ko) * | 2005-11-08 | 2008-05-27 | 한미약품 주식회사 | 신호전달 저해제로서의 퀴나졸린 유도체 및 이의 제조방법 |
EP1948179A1 (en) * | 2005-11-11 | 2008-07-30 | Boehringer Ingelheim International GmbH | Quinazoline derivatives for the treatment of cancer diseases |
DK1948180T3 (da) * | 2005-11-11 | 2013-05-27 | Boehringer Ingelheim Int | Kombinationsbehandling af cancer omfattende EGFR/HER2 inhibitorer |
US7960546B2 (en) * | 2006-01-26 | 2011-06-14 | Boehringer Ingelheim International Gmbh | Process for preparing aminocrotonylamino-substituted quinazoline derivatives |
BRPI0717586A2 (pt) * | 2006-09-18 | 2013-10-29 | Boehringer Ingelheim Int | Método para tratar câncer apresentando mutações do egfr |
PE20100252A1 (es) * | 2008-06-06 | 2010-04-12 | Boehringer Ingelheim Int | Nuevas formulaciones farmaceuticas solidas que comprenden dimaleato de 4-[(3-cloro-4-fluorofenil) amino]-6-{[4-(n,n-dimetilamino)-1-oxo-2-buten-1-il] amino}-7-((s)-tetrahidrofuran-3-iloxi)-quinazolina |
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EP2429520A1 (en) | 2009-05-14 | 2012-03-21 | Boehringer Ingelheim International GmbH | New combination therapy in treatment of oncological and fibrotic diseases |
SG177451A1 (en) * | 2009-07-02 | 2012-02-28 | Newgen Therapeutics Inc | Phosphorus containing quinazoline compounds and methods of use |
DK2451445T3 (da) | 2009-07-06 | 2019-06-24 | Boehringer Ingelheim Int | Fremgangsmåde til at tørre bibw2992, dets salte og faste farmaceutiske formuleringer omfattende denne aktive ingrediens |
EP2509592A1 (en) | 2009-12-07 | 2012-10-17 | Boehringer Ingelheim International GmbH | Bibw 2992 for use in the treatment of triple negative breast cancer |
US20120107304A1 (en) | 2010-04-27 | 2012-05-03 | Boehringer Ingelheim International Gmbh | Combination therapy in treatment of oncological and fibrotic diseases |
WO2012027445A1 (en) | 2010-08-26 | 2012-03-01 | Boehringer Ingelheim International Gmbh | Methods of administering an egfr inhibitor |
EA024026B1 (ru) * | 2010-11-25 | 2016-08-31 | Рациофарм Гмбх | Новые соли и полиморфные формы афатиниба |
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CN102731485B (zh) * | 2011-04-02 | 2016-06-15 | 齐鲁制药有限公司 | 4-(取代苯氨基)喹唑啉衍生物及其制备方法、药物组合物和用途 |
US8828391B2 (en) | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
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