|
US3270960A
(en)
|
1964-09-11 |
1966-09-06 |
Sperry Rand Corp |
Fluid sensor
|
|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4342566A
(en)
|
1980-02-22 |
1982-08-03 |
Scripps Clinic & Research Foundation |
Solid phase anti-C3 assay for detection of immune complexes
|
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
DE3211263A1
(de)
|
1981-03-31 |
1983-01-27 |
Otsuka Pharmaceutical Co. Ltd., Tokyo |
Human-interferon verwandte peptide, antigene und antikoerper, sowie verfahren zu deren herstellung
|
|
DE3238353A1
(de)
|
1982-10-15 |
1984-04-19 |
Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen |
Verfahren zur simultanen quantitativen bestimmung der blutzellen und reagenz hierfuer
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5189147A
(en)
*
|
1984-06-13 |
1993-02-23 |
Massachusetts Institute Of Technology |
Meterodimeric T lymphocyte receptor antibody
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4965188A
(en)
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
|
DE3541033A1
(de)
|
1985-11-19 |
1987-05-21 |
Boehringer Mannheim Gmbh |
Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz
|
|
US4800159A
(en)
|
1986-02-07 |
1989-01-24 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5149625A
(en)
|
1987-08-11 |
1992-09-22 |
President And Fellows Of Harvard College |
Multiplex analysis of DNA
|
|
US4942124A
(en)
|
1987-08-11 |
1990-07-17 |
President And Fellows Of Harvard College |
Multiplex sequencing
|
|
US5667967A
(en)
|
1990-05-01 |
1997-09-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
T-cell receptor varible transcripts as disease related markers
|
|
US5506126A
(en)
|
1988-02-25 |
1996-04-09 |
The General Hospital Corporation |
Rapid immunoselection cloning method
|
|
US5658775A
(en)
|
1988-05-17 |
1997-08-19 |
Sloan-Kettering Institute For Cancer Research |
Double copy retroviral vector
|
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
|
WO1990002806A1
(en)
|
1988-09-01 |
1990-03-22 |
Whitehead Institute For Biomedical Research |
Recombinant retroviruses with amphotropic and ecotropic host ranges
|
|
WO1990004648A1
(en)
|
1988-10-20 |
1990-05-03 |
Alexander Alan Morley |
Method for diagnosis of monoclonality in leukaemia and lymphoma
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5075217A
(en)
|
1989-04-21 |
1991-12-24 |
Marshfield Clinic |
Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5231012A
(en)
|
1989-06-28 |
1993-07-27 |
Schering Corporation |
Nucleic acids encoding cytokine synthesis inhibitory factor (interleukin-10)
|
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
|
US5336598A
(en)
|
1989-11-15 |
1994-08-09 |
National Jewish Center For Immunology And Respiratory Medicine |
Method for diagnosing a superantigen caused pathologial condition via assay of T-cells
|
|
US5298396A
(en)
|
1989-11-15 |
1994-03-29 |
National Jewish Center For Immunology And Respiratory Medicine |
Method for identifying T cells disease involved in autoimmune disease
|
|
US5126022A
(en)
|
1990-02-28 |
1992-06-30 |
Soane Tecnologies, Inc. |
Method and device for moving molecules by the application of a plurality of electrical fields
|
|
US6054034A
(en)
|
1990-02-28 |
2000-04-25 |
Aclara Biosciences, Inc. |
Acrylic microchannels and their use in electrophoretic applications
|
|
AU7906691A
(en)
|
1990-05-23 |
1991-12-10 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
CA2090126C
(en)
|
1990-08-02 |
2002-10-22 |
John W. Schrader |
Methods for the production of proteins with a desired function
|
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
|
IE76732B1
(en)
|
1990-08-07 |
1997-11-05 |
Becton Dickinson Co |
One step test for absolute counts
|
|
US5699798A
(en)
|
1990-08-10 |
1997-12-23 |
University Of Washington |
Method for optically imaging solid tumor tissue
|
|
US5635354A
(en)
|
1991-01-09 |
1997-06-03 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Method for describing the repertoires of antibodies (Ab) and of T-cell receptors (TcR) of an individual's immune system
|
|
US5364759B2
(en)
|
1991-01-31 |
1999-07-20 |
Baylor College Medicine |
Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats
|
|
CA2079881C
(fr)
|
1991-02-12 |
2007-11-06 |
Thierry Hercend |
Sequences nucleotidiques codant pour des regions variables de chaines .beta. des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques
|
|
JP3080178B2
(ja)
|
1991-02-18 |
2000-08-21 |
東洋紡績株式会社 |
核酸配列の増幅方法およびそのための試薬キット
|
|
US6091000A
(en)
|
1991-03-15 |
2000-07-18 |
Duke University |
SCID mouse engrafted with human synovium tissue
|
|
JP3266311B2
(ja)
|
1991-05-02 |
2002-03-18 |
生化学工業株式会社 |
新規ポリペプチドおよびこれを用いる抗hiv剤
|
|
EP0659209A1
(en)
|
1991-07-26 |
1995-06-28 |
The University Of Rochester |
Cancer therapy utilizing malignant cells
|
|
US20040018489A1
(en)
|
1991-09-09 |
2004-01-29 |
Ma Wupo |
Detection of RNA
|
|
US5674679A
(en)
|
1991-09-27 |
1997-10-07 |
Amersham Life Science, Inc. |
DNA cycle sequencing
|
|
US5981179A
(en)
|
1991-11-14 |
1999-11-09 |
Digene Diagnostics, Inc. |
Continuous amplification reaction
|
|
US5256542A
(en)
|
1992-03-09 |
1993-10-26 |
Tanox Biosystems, Inc. |
Selecting low frequency antigen-specific single B lymphocytes with correction for background noise
|
|
US5213960A
(en)
|
1992-03-09 |
1993-05-25 |
Tanox Biosystems, Inc. |
Methods for selecting low frequency antigen-specific single B lymphocytes
|
|
US5837447A
(en)
|
1992-04-15 |
1998-11-17 |
Blood Center Research Foundation, Inc., The |
Monitoring an immune response by analysis of amplified immunoglobulin or T-cell-receptor nucleic acid
|
|
US5587128A
(en)
|
1992-05-01 |
1996-12-24 |
The Trustees Of The University Of Pennsylvania |
Mesoscale polynucleotide amplification devices
|
|
US5498392A
(en)
|
1992-05-01 |
1996-03-12 |
Trustees Of The University Of Pennsylvania |
Mesoscale polynucleotide amplification device and method
|
|
US5981176A
(en)
|
1992-06-17 |
1999-11-09 |
City Of Hope |
Method of detecting and discriminating between nucleic acid sequences
|
|
US5631236A
(en)
|
1993-08-26 |
1997-05-20 |
Baylor College Of Medicine |
Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
|
|
US5426039A
(en)
|
1993-09-08 |
1995-06-20 |
Bio-Rad Laboratories, Inc. |
Direct molecular cloning of primer extended DNA containing an alkane diol
|
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
|
US5714330A
(en)
|
1994-04-04 |
1998-02-03 |
Lynx Therapeutics, Inc. |
DNA sequencing by stepwise ligation and cleavage
|
|
EP0753060A4
(en)
|
1994-04-18 |
1999-11-24 |
New York Society |
PRESERVED T CELL RECEPTOR SEQUENCES
|
|
US6001229A
(en)
|
1994-08-01 |
1999-12-14 |
Lockheed Martin Energy Systems, Inc. |
Apparatus and method for performing microfluidic manipulations for chemical analysis
|
|
US6090592A
(en)
|
1994-08-03 |
2000-07-18 |
Mosaic Technologies, Inc. |
Method for performing amplification of nucleic acid on supports
|
|
FR2724182B1
(fr)
|
1994-09-02 |
1996-12-13 |
Pasteur Institut |
Obtention d'un anticorps monoclonal recombinant a partir d'un anticorps monoclonal humain anti-rhesus d, sa production en cellules d'insecte, et ses utilisations
|
|
US5604097A
(en)
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
|
US6013445A
(en)
|
1996-06-06 |
2000-01-11 |
Lynx Therapeutics, Inc. |
Massively parallel signature sequencing by ligation of encoded adaptors
|
|
US5846719A
(en)
|
1994-10-13 |
1998-12-08 |
Lynx Therapeutics, Inc. |
Oligonucleotide tags for sorting and identification
|
|
US5776737A
(en)
|
1994-12-22 |
1998-07-07 |
Visible Genetics Inc. |
Method and composition for internal identification of samples
|
|
US6919434B1
(en)
*
|
1995-02-20 |
2005-07-19 |
Sankyo Co., Ltd. |
Monoclonal antibodies that bind OCIF
|
|
US6117681A
(en)
|
1995-03-29 |
2000-09-12 |
Bavarian Nordic Research Inst. A/S |
Pseudotyped retroviral particles
|
|
US5698396A
(en)
|
1995-06-07 |
1997-12-16 |
Ludwig Institute For Cancer Research |
Method for identifying auto-immunoreactive substances from a subject
|
|
US6110456A
(en)
|
1995-06-07 |
2000-08-29 |
Yale University |
Oral delivery or adeno-associated viral vectors
|
|
US5866411A
(en)
|
1995-09-08 |
1999-02-02 |
Pedersen; Finn Skou |
Retroviral vector, a replication system for said vector and avian or mammalian cells transfected with said vector
|
|
WO1997013868A1
(en)
|
1995-10-11 |
1997-04-17 |
Leonard Adleman |
Large scale dna sequencing by position sensitive hybridization
|
|
WO1997013877A1
(en)
*
|
1995-10-12 |
1997-04-17 |
Lynx Therapeutics, Inc. |
Measurement of gene expression profiles in toxicity determination
|
|
US5721118A
(en)
|
1995-10-31 |
1998-02-24 |
The Regents Of The University Of California, San Diego |
Mammalian artificial chromosomes and methods of using same
|
|
US6087096A
(en)
|
1995-11-13 |
2000-07-11 |
Dau; Peter C. |
Method of intrafamily fragment analysis of the T cell receptor α and β chain CDR3 regions
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
US20020076725A1
(en)
|
1996-03-13 |
2002-06-20 |
Tomoko Toyosaki-Maeda |
Human t cell clone specific for rheumatoid arthritis
|
|
US6458530B1
(en)
|
1996-04-04 |
2002-10-01 |
Affymetrix Inc. |
Selecting tag nucleic acids
|
|
US6025155A
(en)
|
1996-04-10 |
2000-02-15 |
Chromos Molecular Systems, Inc. |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
|
US6416948B1
(en)
|
1996-06-03 |
2002-07-09 |
The Governors Of The University Of Alberta |
Methods for detection of rearranged DNA
|
|
DE69739357D1
(de)
|
1996-06-04 |
2009-05-28 |
Univ Utah Res Found |
Überwachung der hybridisierung während pcr
|
|
WO1998001738A2
(en)
|
1996-06-20 |
1998-01-15 |
Cornell Research Foundation, Inc. |
Identification of abnormalities in the expression of t and b cell antigen receptors as disease indicators
|
|
US6074827A
(en)
|
1996-07-30 |
2000-06-13 |
Aclara Biosciences, Inc. |
Microfluidic method for nucleic acid purification and processing
|
|
EP0937251B1
(en)
|
1996-09-06 |
2006-11-29 |
Ortho-McNeil Pharmaceutical, Inc. |
Purification of antigen-specific t cells
|
|
WO1998015644A2
(en)
|
1996-09-27 |
1998-04-16 |
The Chinese University Of Hong Kong |
Parallel polynucleotide sequencing method
|
|
US6228589B1
(en)
*
|
1996-10-11 |
2001-05-08 |
Lynx Therapeutics, Inc. |
Measurement of gene expression profiles in toxicity determination
|
|
GB9626815D0
(en)
|
1996-12-23 |
1997-02-12 |
Cemu Bioteknik Ab |
Method of sequencing DNA
|
|
GB9704444D0
(en)
|
1997-03-04 |
1997-04-23 |
Isis Innovation |
Non-invasive prenatal diagnosis
|
|
ATE364718T1
(de)
|
1997-04-01 |
2007-07-15 |
Solexa Ltd |
Verfahren zur vervielfältigung von nukleinsäure
|
|
US6143496A
(en)
|
1997-04-17 |
2000-11-07 |
Cytonix Corporation |
Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
|
|
US6096718A
(en)
|
1997-06-05 |
2000-08-01 |
Gene Targeting Corp. |
Tissue specific adenovirus vectors for breast cancer treatment
|
|
DK1019496T3
(da)
|
1997-07-07 |
2005-01-10 |
Medical Res Council |
In vitro-sorteringsmetode
|
|
US7572582B2
(en)
|
1997-09-12 |
2009-08-11 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6803019B1
(en)
|
1997-10-15 |
2004-10-12 |
Aclara Biosciences, Inc. |
Laminate microstructure device and method for making same
|
|
JP2001520054A
(ja)
|
1997-10-23 |
2001-10-30 |
エグザクト サイエンシーズ コーポレイション |
Pcrを用いる分子診断におけるコンタミネーションを検出するための方法
|
|
US7351578B2
(en)
|
1999-12-10 |
2008-04-01 |
Invitrogen Corp. |
Use of multiple recombination sites with unique specificity in recombinational cloning
|
|
US6210910B1
(en)
|
1998-03-02 |
2001-04-03 |
Trustees Of Tufts College |
Optical fiber biosensor array comprising cell populations confined to microcavities
|
|
US6113913A
(en)
|
1998-06-26 |
2000-09-05 |
Genvec, Inc. |
Recombinant adenovirus
|
|
DE19833738A1
(de)
|
1998-07-27 |
2000-02-03 |
Michael Giesing |
Verfahren zur Isolierung von Krebszellen aus zellhaltigen Körperflüssigkeiten sowie Sets zur Durchführung dieses Verfahrens
|
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
|
DE19844931C1
(de)
|
1998-09-30 |
2000-06-15 |
Stefan Seeger |
Verfahren zur DNS- oder RNS-Sequenzierung
|
|
AR021833A1
(es)
|
1998-09-30 |
2002-08-07 |
Applied Research Systems |
Metodos de amplificacion y secuenciacion de acido nucleico
|
|
SI2112166T1
(sl)
|
1998-12-23 |
2019-05-31 |
Pfizer Inc. |
Človeška monoklonska protitelesa proti CTLA-4
|
|
US6541608B1
(en)
|
1999-02-23 |
2003-04-01 |
Baylor College Of Medicine |
T cell receptor Vβ-Dβ-Jβ sequence and methods for its detection
|
|
US6307024B1
(en)
|
1999-03-09 |
2001-10-23 |
Zymogenetics, Inc. |
Cytokine zalpha11 Ligand
|
|
US6300070B1
(en)
|
1999-06-04 |
2001-10-09 |
Mosaic Technologies, Inc. |
Solid phase methods for amplifying multiple nucleic acids
|
|
US6440706B1
(en)
|
1999-08-02 |
2002-08-27 |
Johns Hopkins University |
Digital amplification
|
|
CN1371416B
(zh)
|
1999-08-24 |
2012-10-10 |
梅达里克斯公司 |
人ctla-4抗体及其应用
|
|
US20040209314A1
(en)
|
1999-09-06 |
2004-10-21 |
Institut National De La Sante Et De La Recherche Medicale France |
Means for detection and purification of CD8+ T lymphocyte populations specific to peptides presented in the context of HLA
|
|
US6235483B1
(en)
|
2000-01-31 |
2001-05-22 |
Agilent Technologies, Inc. |
Methods and kits for indirect labeling of nucleic acids
|
|
US7955794B2
(en)
|
2000-09-21 |
2011-06-07 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US20040121364A1
(en)
|
2000-02-07 |
2004-06-24 |
Mark Chee |
Multiplex nucleic acid reactions
|
|
JP2004505612A
(ja)
|
2000-03-31 |
2004-02-26 |
ユニバーシティ・オブ・サザン・カリフォルニア |
食道腺ガンに関する後成的配列
|
|
AUPQ687600A0
(en)
|
2000-04-13 |
2000-05-11 |
Flinders Technologies Pty Ltd |
A method of detection
|
|
US20030207300A1
(en)
|
2000-04-28 |
2003-11-06 |
Matray Tracy J. |
Multiplex analytical platform using molecular tags
|
|
US6596492B2
(en)
|
2000-07-11 |
2003-07-22 |
Colorado State University Research Foundation |
PCR materials and methods useful to detect canine and feline lymphoid malignancies
|
|
US7567870B1
(en)
|
2000-07-31 |
2009-07-28 |
Institute For Systems Biology |
Multiparameter analysis for predictive medicine
|
|
AU8470301A
(en)
|
2000-08-03 |
2002-02-18 |
Wim-Van Schooten |
Production of humanized antibodies in transgenic animals
|
|
US6939451B2
(en)
|
2000-09-19 |
2005-09-06 |
Aclara Biosciences, Inc. |
Microfluidic chip having integrated electrodes
|
|
AU2002246612B2
(en)
|
2000-10-24 |
2007-11-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Direct multiplex characterization of genomic DNA
|
|
US6778724B2
(en)
|
2000-11-28 |
2004-08-17 |
The Regents Of The University Of California |
Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
|
|
US6947748B2
(en)
|
2000-12-15 |
2005-09-20 |
Adaptix, Inc. |
OFDMA with adaptive subcarrier-cluster configuration and selective loading
|
|
ATE488576T1
(de)
|
2001-02-20 |
2010-12-15 |
Univ Georgia |
Schnellproduktion monoklonaler antikörper
|
|
US7265208B2
(en)
|
2001-05-01 |
2007-09-04 |
The Regents Of The University Of California |
Fusion molecules and treatment of IgE-mediated allergic diseases
|
|
WO2002094009A2
(en)
|
2001-05-24 |
2002-11-28 |
Guard Inc. |
Methods for selecting and producing animals having a predicted level of immune response
|
|
US20050260570A1
(en)
|
2001-05-29 |
2005-11-24 |
Mao Jen-I |
Sequencing by proxy
|
|
US7026121B1
(en)
|
2001-06-08 |
2006-04-11 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
US6720144B1
(en)
|
2001-06-21 |
2004-04-13 |
Quest Diagnostics |
Detection of clonal T-cell receptor-γ gene rearrangement by PCR/temporal temperature gradient gel electrophoresis (TTGE)
|
|
AU2002313683A1
(en)
|
2001-07-15 |
2003-03-03 |
Keck Graduate Institute |
Nucleic acid amplification using nicking agents
|
|
US20030096277A1
(en)
|
2001-08-30 |
2003-05-22 |
Xiangning Chen |
Allele specific PCR for genotyping
|
|
WO2003020979A1
(en)
|
2001-08-31 |
2003-03-13 |
Rosetta Inpharmactis Llc. |
Methods for preparing nucleic acid samples
|
|
ATE290020T1
(de)
|
2001-08-31 |
2005-03-15 |
Avidex Ltd |
Löslicher t zell rezeptor
|
|
DE60234369D1
(de)
|
2001-09-19 |
2009-12-24 |
Alexion Pharma Inc |
Manipulierte matrizen und ihre verwendung bei der single-primer-amplifikation
|
|
US6964850B2
(en)
|
2001-11-09 |
2005-11-15 |
Source Precision Medicine, Inc. |
Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
|
|
GB2382137A
(en)
|
2001-11-20 |
2003-05-21 |
Mats Gullberg |
Nucleic acid enrichment
|
|
GB0128153D0
(en)
|
2001-11-23 |
2002-01-16 |
Bayer Ag |
Profiling of the immune gene repertoire
|
|
WO2003052101A1
(en)
|
2001-12-14 |
2003-06-26 |
Rosetta Inpharmatics, Inc. |
Sample tracking using molecular barcodes
|
|
US20040126829A1
(en)
|
2001-12-18 |
2004-07-01 |
Hildebrand William H. |
Anti-HLA assay and methods
|
|
GB0130267D0
(en)
*
|
2001-12-19 |
2002-02-06 |
Neutec Pharma Plc |
Focussed antibody technology
|
|
WO2003059155A2
(en)
|
2002-01-09 |
2003-07-24 |
Maxx Genetech Co. Ltd |
Method of detecting t-cell proliferation for diagnosis of diseases by gene array
|
|
AUPS028002A0
(en)
|
2002-02-01 |
2002-02-28 |
Ausman Engineering And Associates Pty Ltd |
A bearing assembly
|
|
US7323306B2
(en)
|
2002-04-01 |
2008-01-29 |
Brookhaven Science Associates, Llc |
Genome signature tags
|
|
US7157274B2
(en)
|
2002-06-24 |
2007-01-02 |
Cytonome, Inc. |
Method and apparatus for sorting particles
|
|
CA2485968A1
(en)
|
2002-05-16 |
2004-06-03 |
Vanderbilt University |
Method for predicting autoimmune diseases
|
|
EP1573636A2
(en)
|
2002-07-01 |
2005-09-14 |
Institut Pasteur |
System, method, device, and computer program product for extraction, gathering, manipulation, and analysis of peak data from an automated sequencer
|
|
US7691994B2
(en)
|
2002-07-03 |
2010-04-06 |
Brewer Jamie L |
Compositions and methods for the detection of human T cell receptor variable family gene expression
|
|
CA2800113C
(en)
|
2002-07-12 |
2015-02-03 |
The Johns Hopkins University |
Reagents and methods for engaging unique clonotypic lymphocyte receptors
|
|
WO2004009765A2
(en)
|
2002-07-19 |
2004-01-29 |
Althea Technologies, Inc. |
Strategies for gene expression analysis
|
|
US7157228B2
(en)
|
2002-09-09 |
2007-01-02 |
Bioarray Solutions Ltd. |
Genetic analysis and authentication
|
|
US7459273B2
(en)
|
2002-10-04 |
2008-12-02 |
Affymetrix, Inc. |
Methods for genotyping selected polymorphism
|
|
EP2460889B1
(en)
|
2002-10-11 |
2013-11-20 |
Erasmus Universiteit Rotterdam |
Nucleic acid amplification primers for PCR-based clonality studies of BCL2-IGH rearrangements
|
|
WO2004034031A2
(en)
|
2002-10-11 |
2004-04-22 |
The Regents Of The University Of California |
A method for diagnosis and prognosis of multiple sclerosis
|
|
US20060147925A1
(en)
|
2002-11-13 |
2006-07-06 |
Morley Alexander A |
Method of detection
|
|
EP1566635B1
(en)
|
2002-11-14 |
2011-12-07 |
Vivalis |
Microwell array chip for detecting antigen-specific lymphocyte, method of detecting antigen-specific lymphocyte and method of cloning antigen-specific lymphocyte antigen receptor gene
|
|
AU2003300919A1
(en)
|
2002-12-11 |
2004-06-30 |
Coley Pharmaceutical Gmbh |
5' cpg nucleic acids and methods of use
|
|
WO2004063706A2
(en)
|
2003-01-08 |
2004-07-29 |
Maxx Genetech Co., Ltd. |
Method of detecting over-expression of t-cell receptor genes by real-time pcr
|
|
EP1594950A4
(en)
|
2003-01-29 |
2007-07-25 |
454 Corp |
PRODUCT FOR THE PREPARATION OF SIMPLE STRANDED DNA BANKS
|
|
GB0304068D0
(en)
|
2003-02-22 |
2003-03-26 |
Avidex Ltd |
Substances
|
|
WO2004096985A2
(en)
|
2003-04-24 |
2004-11-11 |
Mayo Foundation For Medical Education And Research |
Methods for assessing biologic diversity
|
|
AU2003902299A0
(en)
|
2003-05-13 |
2003-05-29 |
Flinders Medical Centre |
A method of analysing a marker nucleic acid molecule
|
|
US20070105105A1
(en)
|
2003-05-23 |
2007-05-10 |
Mount Sinai School Of Medicine Of New York University |
Surrogate cell gene expression signatures for evaluating the physical state of a subject
|
|
US20050010030A1
(en)
|
2003-07-02 |
2005-01-13 |
Zang Jingwu Z. |
T cell receptor CDR3 sequence and methods for detecting and treating rheumatoid arthritis
|
|
CA2531105C
(en)
|
2003-07-05 |
2015-03-17 |
The Johns Hopkins University |
Method and compositions for detection and enumeration of genetic variations
|
|
US7574305B2
(en)
|
2003-07-15 |
2009-08-11 |
Bioarray Solutions Ltd. |
Concurrent optimization in selection of primer and capture probe sets for nucleic acid analysis
|
|
US20060228350A1
(en)
|
2003-08-18 |
2006-10-12 |
Medimmune, Inc. |
Framework-shuffling of antibodies
|
|
US20050048498A1
(en)
|
2003-08-29 |
2005-03-03 |
Applera Corporation |
Compositions, methods, and kits for assembling probes
|
|
US7365179B2
(en)
|
2003-09-09 |
2008-04-29 |
Compass Genetics, Llc |
Multiplexed analytical platform
|
|
TWI333977B
(en)
|
2003-09-18 |
2010-12-01 |
Symphogen As |
Method for linking sequences of interest
|
|
FR2863274B1
(fr)
|
2003-12-05 |
2012-11-16 |
Commissariat Energie Atomique |
Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications.
|
|
WO2005053603A2
(en)
|
2003-12-08 |
2005-06-16 |
Yeda Research And Development Co. Ltd. |
Antigen receptor variable region typing
|
|
US20070160994A1
(en)
|
2003-12-15 |
2007-07-12 |
Institut Pasteur |
Repertoire determination of a lymphocyte b population
|
|
US20080166718A1
(en)
|
2003-12-15 |
2008-07-10 |
Institut Pasteur |
Repertoire determination of a lymphocyte B population
|
|
ATE421998T1
(de)
|
2003-12-15 |
2009-02-15 |
Pasteur Institut |
Ermittlung des repertoires von b-lymphozyten populationen
|
|
EP1721014B1
(en)
|
2004-02-18 |
2013-07-17 |
Trustees Of Boston University |
Method for detecting and quantifying rare mutations/polymorphisms
|
|
US20060046258A1
(en)
|
2004-02-27 |
2006-03-02 |
Lapidus Stanley N |
Applications of single molecule sequencing
|
|
US20070161001A1
(en)
|
2004-03-04 |
2007-07-12 |
Dena Leshkowitz |
Quantifying and profiling antibody and t cell receptor gene expression
|
|
JP4480423B2
(ja)
|
2004-03-08 |
2010-06-16 |
独立行政法人科学技術振興機構 |
免疫細胞クローンの拡大の有無の判定方法
|
|
DE102004016437A1
(de)
|
2004-04-04 |
2005-10-20 |
Oligene Gmbh |
Verfahren zur Erkennung von Signaturen in komplexen Genexpressionsprofilen
|
|
US20050250147A1
(en)
|
2004-05-10 |
2005-11-10 |
Macevicz Stephen C |
Digital profiling of polynucleotide populations
|
|
WO2006076025A2
(en)
|
2004-05-14 |
2006-07-20 |
Amaox, Inc. |
Immune cell biosensors and methods of using same
|
|
EP1598429A1
(en)
|
2004-05-19 |
2005-11-23 |
Amplion Ltd. |
Detection of amplicon contamination during PCR exhibiting two different annealing temperatures
|
|
GB0412973D0
(en)
*
|
2004-06-10 |
2004-07-14 |
Celltech R&D Ltd |
Identification of antibody producing cells
|
|
US20060020397A1
(en)
|
2004-07-21 |
2006-01-26 |
Kermani Bahram G |
Methods for nucleic acid and polypeptide similarity search employing content addressable memories
|
|
US20060019304A1
(en)
|
2004-07-26 |
2006-01-26 |
Paul Hardenbol |
Simultaneous analysis of multiple genomes
|
|
US20060094018A1
(en)
|
2004-08-03 |
2006-05-04 |
Bauer A R Jr |
Discovery and a method for the early detection of pancreatic cancer and other disease conditions
|
|
US7820382B2
(en)
|
2004-08-03 |
2010-10-26 |
Bauer A Robert |
Method for the early detection of breast cancer, lung cancer, pancreatic cancer and colon polyps, growths and cancers as well as other gastrointestinal disease conditions and the preoperative and postoperative monitoring of transplanted organs from the donor and in the recipient and their associated conditions related and unrelated to the organ transplantation
|
|
ME01803B
(me)
|
2004-08-05 |
2010-12-31 |
Genentech Inc |
Humanizovani anti-cmet antagonisti
|
|
CA2580412A1
(en)
|
2004-09-13 |
2006-03-23 |
Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services |
Compositions comprising t cell receptors and methods of use thereof
|
|
US7170050B2
(en)
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
WO2006050138A2
(en)
|
2004-10-29 |
2006-05-11 |
Benaroya Research Institute At Virginia Mason |
Methods of generating antigen-specific cd4+cd25+ regulatory t cells, compositions and methods of use
|
|
US7966988B2
(en)
|
2005-01-11 |
2011-06-28 |
Exxonmobil Research And Engineering Company |
Method for controlling soot induced lubricant viscosity increase
|
|
US8029783B2
(en)
|
2005-02-02 |
2011-10-04 |
Genentech, Inc. |
DR5 antibodies and articles of manufacture containing same
|
|
FR2881436B1
(fr)
|
2005-02-03 |
2007-04-27 |
Commissariat Energie Atomique |
Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
|
|
US7393665B2
(en)
|
2005-02-10 |
2008-07-01 |
Population Genetics Technologies Ltd |
Methods and compositions for tagging and identifying polynucleotides
|
|
CA2598025A1
(en)
|
2005-02-16 |
2006-08-24 |
Wyeth |
Methods and systems for diagnosis, prognosis and selection of treatment of leukemia
|
|
US7537894B2
(en)
|
2005-03-02 |
2009-05-26 |
The University Of Chicago |
Methods and kits for monitoring Barrett's metaplasia
|
|
WO2006099164A2
(en)
|
2005-03-10 |
2006-09-21 |
Applera Corporation |
Methods for multiplex amplification
|
|
US20060211030A1
(en)
|
2005-03-16 |
2006-09-21 |
Sydney Brenner |
Methods and compositions for assay readouts on multiple analytical platforms
|
|
JP2008538496A
(ja)
|
2005-04-12 |
2008-10-30 |
454 ライフ サイエンシーズ コーポレイション |
ウルトラディープ配列決定を用いて配列変異体を決定するための方法
|
|
WO2006116155A2
(en)
|
2005-04-21 |
2006-11-02 |
The Regents Of The University Of California |
A method for diagnosis and prognosis of multiple sclerosis subtypes
|
|
US20060263789A1
(en)
|
2005-05-19 |
2006-11-23 |
Robert Kincaid |
Unique identifiers for indicating properties associated with entities to which they are attached, and methods for using
|
|
US7208795B2
(en)
|
2005-05-24 |
2007-04-24 |
Atmel Corporation |
Low-cost, low-voltage single-layer polycrystalline EEPROM memory cell integration into BiCMOS technology
|
|
US8426146B2
(en)
|
2005-06-03 |
2013-04-23 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Multiparameteric method for assessing immune system status
|
|
US20090264299A1
(en)
|
2006-02-24 |
2009-10-22 |
Complete Genomics, Inc. |
High throughput genome sequencing on DNA arrays
|
|
CA2611671C
(en)
|
2005-06-15 |
2013-10-08 |
Callida Genomics, Inc. |
Single molecule arrays for genetic and chemical analysis
|
|
WO2007008759A2
(en)
|
2005-07-07 |
2007-01-18 |
Hematologics, Inc. |
Methods for detecting and confirming minimal disease in a cancer patient
|
|
US20070020640A1
(en)
|
2005-07-21 |
2007-01-25 |
Mccloskey Megan L |
Molecular encoding of nucleic acid templates for PCR and other forms of sequence analysis
|
|
GB0521521D0
(en)
|
2005-10-21 |
2005-11-30 |
Medical Res Council |
Diagnostic methods and kits
|
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
|
US20070105165A1
(en)
|
2005-11-04 |
2007-05-10 |
Charles Goolsby |
Composite profiles of cell antigens and target signal transduction proteins for analysis and clinical management of hematologic cancers
|
|
US7375211B2
(en)
|
2005-11-18 |
2008-05-20 |
Kou Zhong C |
Method for detection and quantification of T-cell receptor Vβ repertoire
|
|
US8137936B2
(en)
|
2005-11-29 |
2012-03-20 |
Macevicz Stephen C |
Selected amplification of polynucleotides
|
|
US7544473B2
(en)
|
2006-01-23 |
2009-06-09 |
Population Genetics Technologies Ltd. |
Nucleic acid analysis using sequence tokens
|
|
WO2007087312A2
(en)
|
2006-01-23 |
2007-08-02 |
Population Genetics Technologies Ltd. |
Molecular counting
|
|
AU2007222798A1
(en)
|
2006-03-06 |
2007-09-13 |
Symphogen A/S |
Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections
|
|
ES2546848T3
(es)
|
2006-03-10 |
2015-09-29 |
Epigenomics Ag |
Un método para identificar una muestra biológica para el análisis de la metilación
|
|
JP5389638B2
(ja)
|
2006-04-04 |
2014-01-15 |
キージーン ナムローゼ フェンノートシャップ |
制限断片に基づく分子マーカーのハイスループットな検出
|
|
CA2652086A1
(en)
|
2006-05-11 |
2007-11-22 |
University Of Maryland Biotechnology Institute |
A general method for generating human antibody responses in vitro
|
|
WO2007136518A2
(en)
|
2006-05-17 |
2007-11-29 |
Torrey Pines Institute For Molecular Studies |
Treatment of autoimmune disorders
|
|
WO2007139584A2
(en)
|
2006-05-25 |
2007-12-06 |
Institute For Advanced Study |
Methods for identifying sequence motifs, and applications thereof
|
|
US7833716B2
(en)
|
2006-06-06 |
2010-11-16 |
Gen-Probe Incorporated |
Tagged oligonucleotides and their use in nucleic acid amplification methods
|
|
JP2009539411A
(ja)
|
2006-06-12 |
2009-11-19 |
パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド |
分析反応を行うための基板
|
|
EP2589668A1
(en)
|
2006-06-14 |
2013-05-08 |
Verinata Health, Inc |
Rare cell analysis using sample splitting and DNA tags
|
|
US20100027896A1
(en)
|
2006-06-28 |
2010-02-04 |
Amir Geva |
Automated application interaction using a virtual operator
|
|
US7553949B2
(en)
|
2006-06-30 |
2009-06-30 |
Applied Biosystems, Llc |
Reversible terminator nucleotides and methods of use
|
|
WO2008108803A2
(en)
|
2006-07-13 |
2008-09-12 |
Amaox, Ltd. |
Immune cell biosensors and methods of using same
|
|
US8394590B2
(en)
|
2006-08-02 |
2013-03-12 |
California Institute Of Technology |
Capture agents and related methods and systems for detecting and/or sorting targets
|
|
US20080274904A1
(en)
|
2006-08-10 |
2008-11-06 |
Niall Anthony Gormley |
Method of target enrichment
|
|
WO2008026927A2
(en)
|
2006-08-30 |
2008-03-06 |
Academisch Medisch Centrum |
Process for displaying t- and b-cell receptor repertoires
|
|
US8088379B2
(en)
|
2006-09-26 |
2012-01-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Modified T cell receptors and related materials and methods
|
|
WO2008039694A2
(en)
|
2006-09-26 |
2008-04-03 |
St. Jude Children's Research Hospital |
Methods and compositions for monitoring t cell receptor diversity
|
|
JP5026047B2
(ja)
|
2006-10-18 |
2012-09-12 |
株式会社膠原病研究所 |
自己免疫疾患の発症に関わる自己応答性t細胞またはt細胞受容体の同定方法、およびその利用
|
|
US8148067B2
(en)
|
2006-11-09 |
2012-04-03 |
Xdx, Inc. |
Methods for diagnosing and monitoring the status of systemic lupus erythematosus
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US7862999B2
(en)
|
2007-01-17 |
2011-01-04 |
Affymetrix, Inc. |
Multiplex targeted amplification using flap nuclease
|
|
EP2121983A2
(en)
|
2007-02-02 |
2009-11-25 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
RU2459868C2
(ru)
|
2007-03-01 |
2012-08-27 |
Симфоген А/С |
Способ клонирования когнатных антител
|
|
WO2008147879A1
(en)
|
2007-05-22 |
2008-12-04 |
Ryan Golhar |
Automated method and device for dna isolation, sequence determination, and identification
|
|
CN101720359A
(zh)
|
2007-06-01 |
2010-06-02 |
454生命科学公司 |
从多重混合物中识别个别样本的系统和方法
|
|
US8454906B2
(en)
|
2007-07-24 |
2013-06-04 |
The Regents Of The University Of California |
Microfabricated droplet generator for single molecule/cell genetic analysis in engineered monodispersed emulsions
|
|
JP2010534474A
(ja)
|
2007-07-26 |
2010-11-11 |
パシフィック バイオサイエンシーズ オブ カリフォルニア, インコーポレイテッド |
分子冗長配列決定
|
|
ITRM20070429A1
(it)
|
2007-08-06 |
2009-02-07 |
Uni Cattolica Del Sacro Cuor E |
Mezzi per la diagnosi la prevenzione e la cura dell'artrite reumatoide.
|
|
US20090042737A1
(en)
|
2007-08-09 |
2009-02-12 |
Katz Andrew S |
Methods and Devices for Correlated, Multi-Parameter Single Cell Measurements and Recovery of Remnant Biological Material
|
|
US8268564B2
(en)
|
2007-09-26 |
2012-09-18 |
President And Fellows Of Harvard College |
Methods and applications for stitched DNA barcodes
|
|
US20100285984A1
(en)
|
2007-09-28 |
2010-11-11 |
Wettstein Peter J |
Assessing t cell repertoires
|
|
US7960116B2
(en)
|
2007-09-28 |
2011-06-14 |
Pacific Biosciences Of California, Inc. |
Nucleic acid sequencing methods and systems
|
|
BRPI0820707A2
(pt)
|
2007-11-07 |
2015-06-16 |
Genentech Inc |
Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40
|
|
EP2060637A1
(en)
|
2007-11-14 |
2009-05-20 |
Koninklijke Philips Electronics N.V. |
Means and methods for detection of nucleic acids
|
|
WO2009070767A2
(en)
|
2007-11-28 |
2009-06-04 |
Whitehead Institute For Biomedical Research |
Systemic instigation systems to study tumor growth or metastasis
|
|
EP2062982A1
(fr)
|
2007-11-26 |
2009-05-27 |
ImmunID |
Procédé d'étude de la diversité combinatoire V(D)J
|
|
CN101225441B
(zh)
|
2007-12-05 |
2010-12-01 |
浙江大学 |
一种检测克隆特异性t淋巴细胞tcr bv cdr3基因组成的方法
|
|
US20100021894A1
(en)
|
2007-12-20 |
2010-01-28 |
Northwestern University |
Nanoparticle-Based Colorimetric Detection Of Cysteine
|
|
US8621502B2
(en)
|
2007-12-21 |
2013-12-31 |
Microsoft Corporation |
Obtaining user reactions to video
|
|
US7767400B2
(en)
|
2008-02-03 |
2010-08-03 |
Helicos Biosciences Corporation |
Paired-end reads in sequencing by synthesis
|
|
EP2088432A1
(en)
|
2008-02-11 |
2009-08-12 |
MorphoSys AG |
Methods for identification of an antibody or a target
|
|
EP2088205A1
(en)
|
2008-02-11 |
2009-08-12 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
PSMB10: A diagnosis marker and therapeutic target of chronic rejection.
|
|
CN104031984A
(zh)
|
2008-02-28 |
2014-09-10 |
俄亥俄州立大学研究基金会 |
用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物
|
|
EP2250496A4
(en)
|
2008-02-28 |
2011-08-31 |
Univ Ohio State Res Found |
MICRO-RNA SIGNATURES ASSOCIATED WITH CYTOGENETICS AND PROGNOSIS IN ACUTE MYELOID LEUKEMIA (AML) AND USES THEREOF
|
|
US20090226975A1
(en)
|
2008-03-10 |
2009-09-10 |
Illumina, Inc. |
Constant cluster seeding
|
|
TW200938840A
(en)
|
2008-03-12 |
2009-09-16 |
Emo Biomedicine Corp |
A method for in vitro study of immune modulation using pig blood cell
|
|
EP2100970B1
(en)
|
2008-03-13 |
2017-05-10 |
National Institute of Immunology |
Ig genes specific oligonucleotides and uses thereof
|
|
EP3045542B1
(en)
|
2008-03-28 |
2016-11-16 |
Pacific Biosciences of California, Inc. |
Methods for nucleic acid sequencing
|
|
EP2107040B1
(en)
|
2008-03-31 |
2011-10-26 |
Sony Deutschland Gmbh |
A method of fabricating a membrane having a tapered pore
|
|
EP2281065B1
(en)
|
2008-04-16 |
2015-09-09 |
HudsonAlpha Institute For Biotechnology |
Method for evaluating and comparing immunorepertoires
|
|
US8911948B2
(en)
|
2008-04-30 |
2014-12-16 |
Integrated Dna Technologies, Inc. |
RNase H-based assays utilizing modified RNA monomers
|
|
WO2009137832A2
(en)
|
2008-05-09 |
2009-11-12 |
Duke University |
Autoantibodies in the detection and treatment of cancer
|
|
US9068181B2
(en)
|
2008-05-23 |
2015-06-30 |
The General Hospital Corporation |
Microfluidic droplet encapsulation
|
|
DE102008025656B4
(de)
|
2008-05-28 |
2016-07-28 |
Genxpro Gmbh |
Verfahren zur quantitativen Analyse von Nukleinsäuren, Marker dafür und deren Verwendung
|
|
WO2009145925A1
(en)
|
2008-05-30 |
2009-12-03 |
Massachusetts Institute Of Technology |
Compositions and methods for spatial separation and screening of cells
|
|
WO2009151628A2
(en)
|
2008-06-12 |
2009-12-17 |
Gov't Of The Usa, As Represented By The Secretary, Department Of Health Human Services |
Monitoring tcr-b to determine hiv therapy and disease progression
|
|
SG182951A1
(en)
|
2008-06-25 |
2012-08-30 |
Baylor Res Inst |
Blood transcriptional signature of mycobacterium tuberculosis infection
|
|
US8394583B2
(en)
|
2008-07-24 |
2013-03-12 |
The Board Of Regents Of The University Of Texas System |
VH4 codon signature for multiple sclerosis
|
|
KR20110036638A
(ko)
|
2008-07-25 |
2011-04-07 |
리차드 더블유. 와그너 |
단백질 스크리닝 방법
|
|
US8586310B2
(en)
|
2008-09-05 |
2013-11-19 |
Washington University |
Method for multiplexed nucleic acid patch polymerase chain reaction
|
|
CA2738578C
(en)
|
2008-09-23 |
2021-05-04 |
Quantalife, Inc. |
Droplet-based assay system
|
|
US9156010B2
(en)
|
2008-09-23 |
2015-10-13 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
|
US8699361B2
(en)
|
2008-09-30 |
2014-04-15 |
Qualcomm Incorporated |
Out-of-synchronization handling method and apparatus
|
|
US20100137143A1
(en)
|
2008-10-22 |
2010-06-03 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US8546128B2
(en)
|
2008-10-22 |
2013-10-01 |
Life Technologies Corporation |
Fluidics system for sequential delivery of reagents
|
|
US9394567B2
(en)
|
2008-11-07 |
2016-07-19 |
Adaptive Biotechnologies Corporation |
Detection and quantification of sample contamination in immune repertoire analysis
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US20140234835A1
(en)
|
2008-11-07 |
2014-08-21 |
Sequenta, Inc. |
Rare clonotypes and uses thereof
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
CN102272327B
(zh)
|
2008-11-07 |
2015-11-25 |
赛昆塔公司 |
通过序列分析监测状况的方法
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US8691510B2
(en)
|
2008-11-07 |
2014-04-08 |
Sequenta, Inc. |
Sequence analysis of complex amplicons
|
|
WO2010060051A2
(en)
|
2008-11-21 |
2010-05-27 |
Emory University |
Systems biology approach predicts the immunogenicity of vaccines
|
|
US8367330B2
(en)
|
2008-12-22 |
2013-02-05 |
Quest Diagnostics Investments Incorporated |
Methods for detecting TCR-gamma gene rearrangement
|
|
CN102272326B
(zh)
|
2008-12-30 |
2014-11-12 |
森托科尔奥索生物科技公司 |
预测强直性脊柱炎患者对于抗TNFα抗体的临床反应的血清标记物
|
|
DK2387627T3
(en)
|
2009-01-15 |
2016-07-04 |
Adaptive Biotechnologies Corp |
Adaptive immunity profiling and methods for producing monoclonal antibodies
|
|
CN102333891A
(zh)
|
2009-01-20 |
2012-01-25 |
利兰·斯坦福青年大学托管委员会 |
用于药靶诊断、预后和鉴别的单细胞基因表达
|
|
US20100323348A1
(en)
|
2009-01-31 |
2010-12-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Methods and Compositions for Using Error-Detecting and/or Error-Correcting Barcodes in Nucleic Acid Amplification Process
|
|
US8673627B2
(en)
|
2009-05-29 |
2014-03-18 |
Life Technologies Corporation |
Apparatus and methods for performing electrochemical reactions
|
|
US8574835B2
(en)
|
2009-05-29 |
2013-11-05 |
Life Technologies Corporation |
Scaffolded nucleic acid polymer particles and methods of making and using
|
|
RU2539032C2
(ru)
|
2009-06-25 |
2015-01-10 |
Фред Хатчинсон Кансэр Рисёч Сентер |
Способ измерения искусственного иммунитета
|
|
US8497071B2
(en)
|
2009-06-29 |
2013-07-30 |
California Institute Of Technology |
Isolation of unknown rearranged T-cell receptors from single cells
|
|
US20120308999A1
(en)
|
2009-07-17 |
2012-12-06 |
Aartik Sarma |
Detection of short rna sequences
|
|
US8467973B2
(en)
|
2009-07-28 |
2013-06-18 |
Promising Future, Llc |
Pairing processes for preparing alloreactive cytotoxic T cells
|
|
WO2011035870A1
(en)
|
2009-09-22 |
2011-03-31 |
Roche Diagnostics Gmbh |
Determination of kir haplotypes associated with disease
|
|
GB0917094D0
(en)
|
2009-09-29 |
2009-11-11 |
Ucl Biomedica Plc |
T-cell receptor
|
|
US9043160B1
(en)
|
2009-11-09 |
2015-05-26 |
Sequenta, Inc. |
Method of determining clonotypes and clonotype profiles
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
US9315857B2
(en)
|
2009-12-15 |
2016-04-19 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse label-tags
|
|
US8545248B2
(en)
|
2010-01-07 |
2013-10-01 |
Life Technologies Corporation |
System to control fluid flow based on a leak detected by a sensor
|
|
KR101323827B1
(ko)
|
2010-01-08 |
2013-10-31 |
키스트 유럽 에프게엠베하 |
강직성척추염 진단용 프라이머 및 이를 이용한 강직성 척추염 진단 방법
|
|
GB201000375D0
(en)
|
2010-01-09 |
2010-02-24 |
Univ Cardiff |
T Cell clonotypes
|
|
WO2011106738A2
(en)
|
2010-02-25 |
2011-09-01 |
Fred Hutchinson Cancer Research Center |
Use of tcr clonotypes as biomarkers for disease
|
|
EP2367000A1
(en)
|
2010-03-04 |
2011-09-21 |
Charité Universitätsmedizin Berlin |
High throughput analysis of T-cell receptor repertoires
|
|
SG10201503534RA
(en)
|
2010-05-06 |
2015-06-29 |
Sequenta Inc |
Monitoring health and disease status using clonotype profiles
|
|
CA2796822C
(en)
|
2010-05-07 |
2021-10-05 |
The Board Of Trustees Of The Leland Standford Junior University |
Measurement and comparison of immune diversity by high-throughput sequencing
|
|
US20130123120A1
(en)
|
2010-05-18 |
2013-05-16 |
Natera, Inc. |
Highly Multiplex PCR Methods and Compositions
|
|
EP3290529B1
(en)
|
2010-06-11 |
2019-05-22 |
Life Technologies Corporation |
Alternative nucleotide flows in sequencing-by-synthesis methods
|
|
SG186787A1
(en)
|
2010-07-23 |
2013-02-28 |
Esoterix Genetic Lab Llc |
Identification of differentially represented fetal or maternal genomic regions and uses thereof
|
|
EP3376225A1
(en)
|
2010-08-06 |
2018-09-19 |
Ludwig-Maximilians-Universität München |
Identification of t cell target antigens
|
|
WO2012027503A2
(en)
|
2010-08-24 |
2012-03-01 |
Fred Hutchinson Cancer Research Center |
Method of measuring adaptive immunity
|
|
BR112013006718B1
(pt)
|
2010-09-20 |
2021-12-07 |
Tron - Translationale Onkologie An Der Universitätsmedizin Der Johannes Gutenberguniversität Mainz Gemeinnutzige Gmbh |
Receptor de células t com especificidade para ny-eso-1, composição farmacêutica compreendendo o mesmo e uso do mesmo
|
|
EP3115468B1
(en)
|
2010-09-21 |
2018-07-25 |
Agilent Technologies, Inc. |
Increasing confidence of allele calls with molecular counting
|
|
WO2012045012A2
(en)
|
2010-09-30 |
2012-04-05 |
Raindance Technologies, Inc. |
Sandwich assays in droplets
|
|
WO2012048341A1
(en)
|
2010-10-08 |
2012-04-12 |
President And Fellows Of Harvard College |
High-throughput single cell barcoding
|
|
ES2730951T3
(es)
|
2010-10-08 |
2019-11-13 |
Harvard College |
Secuenciación inmune de alto rendimiento
|
|
US8753816B2
(en)
|
2010-10-26 |
2014-06-17 |
Illumina, Inc. |
Sequencing methods
|
|
AU2011323107B2
(en)
|
2010-11-05 |
2015-09-10 |
Illumina, Inc. |
Linking sequence reads using paired code tags
|
|
WO2012083069A2
(en)
|
2010-12-15 |
2012-06-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Measurement and monitoring of cell clonality
|
|
US20140057799A1
(en)
|
2010-12-16 |
2014-02-27 |
Gigagen |
System and Methods for Massively Parallel Analysis of Nucleic Acids in Single Cells
|
|
WO2012118555A1
(en)
|
2010-12-29 |
2012-09-07 |
Life Technologies Corporation |
Time-warped background signal for sequencing-by-synthesis operations
|
|
EP2658999B1
(en)
|
2010-12-30 |
2019-03-13 |
Life Technologies Corporation |
Models for analyzing data from sequencing-by-synthesis operations
|
|
CN103842379A
(zh)
|
2011-03-09 |
2014-06-04 |
细胞信号科技公司 |
用于生成单克隆抗体的方法和试剂
|
|
US8759036B2
(en)
|
2011-03-21 |
2014-06-24 |
Affymetrix, Inc. |
Methods for synthesizing pools of probes
|
|
AU2012242847B2
(en)
|
2011-04-15 |
2017-01-19 |
The Johns Hopkins University |
Safe sequencing system
|
|
SG194233A1
(en)
|
2011-04-28 |
2013-12-30 |
Univ Leland Stanford Junior |
Identification of polynucleotides associated with a sample
|
|
HRP20230443T1
(hr)
|
2011-05-24 |
2023-09-15 |
BioNTech SE |
Individualizirana cjepiva protiv raka
|
|
US9834766B2
(en)
|
2011-09-02 |
2017-12-05 |
Atreca, Inc. |
DNA barcodes for multiplexed sequencing
|
|
US20140356339A1
(en)
|
2011-09-09 |
2014-12-04 |
Sequenta Inc. |
Sequence-based measures of immune response
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
US20140256592A1
(en)
|
2011-10-11 |
2014-09-11 |
Sequenta, Inc. |
Determining responsiveness of autoimmune patients to dmard treatment
|
|
HK1201565A1
(en)
|
2011-10-21 |
2015-09-04 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
US20130137108A1
(en)
|
2011-10-25 |
2013-05-30 |
Anubhav Tripathi |
Magnetic bead separation apparatus and method
|
|
WO2013066726A1
(en)
|
2011-11-04 |
2013-05-10 |
Sequenta, Inc. |
T-cell receptor clonotypes shared among ankylosing spondylitis patients
|
|
WO2013085855A1
(en)
|
2011-12-05 |
2013-06-13 |
Sequenta, Inc. |
Clonotypes as biometric specimen tags
|
|
EP2788509B1
(en)
|
2011-12-09 |
2018-07-11 |
Adaptive Biotechnologies Corporation |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
JP2015501644A
(ja)
|
2011-12-09 |
2015-01-19 |
シーケンタ インコーポレイテッド |
免疫活性化を測定する方法
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
WO2013090390A2
(en)
|
2011-12-13 |
2013-06-20 |
Sequenta, Inc. |
Method of measuring immune activation
|
|
US20140349883A1
(en)
|
2011-12-20 |
2014-11-27 |
Sequenta, Inc. |
Monitoring transformation of follicular lymphoma to diffuse large b-cell lymphoma by immune repertoire analysis
|
|
WO2013112655A1
(en)
|
2012-01-24 |
2013-08-01 |
Gigagen, Inc. |
Method for correction of bias in multiplexed amplification
|
|
IN2014MN01780A
(pl)
|
2012-02-09 |
2015-07-03 |
Memed Diagnostics Ltd |
|
|
ES2855130T3
(es)
|
2012-02-17 |
2021-09-23 |
Hutchinson Fred Cancer Res |
Composiciones y métodos para identificar mutaciones de manera precisa
|
|
WO2013130512A2
(en)
|
2012-02-27 |
2013-09-06 |
The University Of North Carolina At Chapel Hill |
Methods and uses for molecular tags
|
|
WO2013131074A1
(en)
|
2012-03-02 |
2013-09-06 |
Diogenix, Inc. |
Methods and reagents for evaluating autoimmune disease and determining antibody repertoire
|
|
WO2013134302A1
(en)
|
2012-03-05 |
2013-09-12 |
Sequenta, Inc. |
Monitoring immune responsiveness to cancer vaccination
|
|
ES2662128T3
(es)
|
2012-03-05 |
2018-04-05 |
Adaptive Biotechnologies Corporation |
Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes
|
|
US20150038346A1
(en)
|
2012-03-05 |
2015-02-05 |
Sequenta, Inc. |
Monitoring immune responsiveness to cancer vaccination
|
|
WO2013138510A1
(en)
|
2012-03-13 |
2013-09-19 |
Patel Abhijit Ajit |
Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
|
|
EP2836611A4
(en)
|
2012-04-13 |
2015-12-30 |
Sequenta Inc |
DETECTION AND QUANTIFICATION OF SAMPLE CONTAMINATION IN AN IMMUNOLOGICAL DIRECTORY ANALYSIS
|
|
WO2013158936A1
(en)
|
2012-04-20 |
2013-10-24 |
Sequenta, Inc |
Monitoring immunoglobulin heavy chain evolution in b-cell acute lymphoblastic leukemia
|
|
AU2013251701A1
(en)
|
2012-04-24 |
2014-10-30 |
Gen9, Inc. |
Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
|
|
US9150905B2
(en)
|
2012-05-08 |
2015-10-06 |
Adaptive Biotechnologies Corporation |
Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions
|
|
WO2013181428A2
(en)
|
2012-05-31 |
2013-12-05 |
Sequenta, Inc. |
Predicting relapse of chronic lymphocytic leukemia patients treated by allogeneic stem cell transplantation
|
|
US20130324422A1
(en)
|
2012-06-04 |
2013-12-05 |
Sequenta, Inc. |
Detecting disease-correlated clonotypes from fixed samples
|
|
SG11201407888RA
(en)
|
2012-06-11 |
2014-12-30 |
Sequenta Inc |
Method of sequence determination using sequence tags
|
|
AU2013273987B2
(en)
|
2012-06-15 |
2018-08-09 |
Adaptive Biotechnologies Corporation |
Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
|
|
US20150154352A1
(en)
|
2012-06-21 |
2015-06-04 |
Gigagen, Inc. |
System and Methods for Genetic Analysis of Mixed Cell Populations
|
|
US20150247182A1
(en)
|
2012-07-24 |
2015-09-03 |
Adaptive Biotechnologies Corp. |
Single cell analysis using sequence tags
|
|
JP2015524282A
(ja)
|
2012-08-10 |
2015-08-24 |
シーケンタ インコーポレイテッド |
配列タグを用いた高感度突然変異検出
|
|
US20140065629A1
(en)
|
2012-08-29 |
2014-03-06 |
Israel Barken |
Methods of treating diseases
|
|
CA2884246C
(en)
|
2012-09-24 |
2023-11-07 |
Cb Biotechnologies, Inc. |
Multiplex pyrosequencing using non-interfering noise-canceling polynucleotide identification tags
|
|
EP2909342A4
(en)
|
2012-10-19 |
2016-06-22 |
Adaptive Biotechnologies Corp |
MONITORING OF LARGE B-CELL DIFFUSED LYMPHOMA FROM PERIPHERAL BLOOD SAMPLES
|
|
CA2888514A1
(en)
|
2012-10-19 |
2014-04-24 |
Sequenta, Inc. |
Monitoring clonotypes of plasma cell proliferative disorders in peripheral blood
|
|
WO2015160439A2
(en)
|
2014-04-17 |
2015-10-22 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
WO2014066184A1
(en)
|
2012-10-22 |
2014-05-01 |
Sequenta, Inc. |
Monitoring mantle cell lymphoma clonotypes in peripheral blood after immunotransplant
|
|
ES2748204T3
(es)
|
2013-02-22 |
2020-03-13 |
Adaptive Biotechnologies Corp |
Procedimiento para seleccionar clonotipos raros
|
|
US20140255944A1
(en)
|
2013-03-08 |
2014-09-11 |
Sequenta, Inc. |
Monitoring treatment-resistant clones in lymphoid and myeloid neoplasms by relative levels of evolved clonotypes
|
|
US20140255929A1
(en)
|
2013-03-11 |
2014-09-11 |
Sequenta, Inc. |
Mosaic tags for labeling templates in large-scale amplifications
|
|
WO2014145992A1
(en)
|
2013-03-15 |
2014-09-18 |
Adaptive Biotechnologies Corporation |
Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
US20160186260A1
(en)
|
2013-07-26 |
2016-06-30 |
Sequenta, Llc |
Cancer vaccination with antigen evolution
|
|
AU2014337063A1
(en)
|
2013-10-18 |
2016-05-19 |
Adaptive Biotechnologies Corp. |
Predicting patient responsiveness to immune checkpoint inhibitors
|
|
EP3092318A4
(en)
|
2014-01-10 |
2017-08-16 |
Adaptive Biotechnologies Corp. |
Methods for defining and predicting immune response to allograft
|
|
US20150218656A1
(en)
|
2014-02-03 |
2015-08-06 |
Adaptive Biotechnologies Corp. |
Methods for detection and diagnosis of a lymphoid malignancy using high throughput sequencing
|
|
ES2741740T3
(es)
|
2014-03-05 |
2020-02-12 |
Adaptive Biotechnologies Corp |
Métodos que usan moléculas sintéticas que contienen segmentos de nucleótidos aleatorios
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
EP3715455A1
(en)
|
2014-10-29 |
2020-09-30 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
US11047008B2
(en)
|
2015-02-24 |
2021-06-29 |
Adaptive Biotechnologies Corporation |
Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
|
|
WO2016161273A1
(en)
|
2015-04-01 |
2016-10-06 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible t cell receptors specific for an antigenic target
|