FR2881436B1 - Procede de determination de la diversite des lymphocytes t dans un echantillon biologique - Google Patents

Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Info

Publication number
FR2881436B1
FR2881436B1 FR0501073A FR0501073A FR2881436B1 FR 2881436 B1 FR2881436 B1 FR 2881436B1 FR 0501073 A FR0501073 A FR 0501073A FR 0501073 A FR0501073 A FR 0501073A FR 2881436 B1 FR2881436 B1 FR 2881436B1
Authority
FR
France
Prior art keywords
lymphocytes
diversity
determining
biological sample
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0501073A
Other languages
English (en)
Other versions
FR2881436A1 (fr
Inventor
Serge Candeias
Cedric Touvrey
Marche Evelyne Jouvin
Patrice Marche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0501073A priority Critical patent/FR2881436B1/fr
Priority to CA002596389A priority patent/CA2596389A1/fr
Priority to US11/883,633 priority patent/US20080286777A1/en
Priority to JP2007553658A priority patent/JP2008528049A/ja
Priority to EP06709239A priority patent/EP1846574A1/fr
Priority to PCT/FR2006/000247 priority patent/WO2006082324A1/fr
Publication of FR2881436A1 publication Critical patent/FR2881436A1/fr
Application granted granted Critical
Publication of FR2881436B1 publication Critical patent/FR2881436B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR0501073A 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique Expired - Fee Related FR2881436B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0501073A FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
CA002596389A CA2596389A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
US11/883,633 US20080286777A1 (en) 2005-02-03 2006-02-03 Method of Determining the Diversity of T Lymphocytes in a Biological Sample
JP2007553658A JP2008528049A (ja) 2005-02-03 2006-02-03 生物学的サンプル中のｔリンパ球の多様性を決定する方法
EP06709239A EP1846574A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
PCT/FR2006/000247 WO2006082324A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501073A FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Publications (2)

Publication Number Publication Date
FR2881436A1 FR2881436A1 (fr) 2006-08-04
FR2881436B1 true FR2881436B1 (fr) 2007-04-27

Family

ID=34953893

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0501073A Expired - Fee Related FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Country Status (6)

Country Link
US (1) US20080286777A1 (fr)
EP (1) EP1846574A1 (fr)
JP (1) JP2008528049A (fr)
CA (1) CA2596389A1 (fr)
FR (1) FR2881436B1 (fr)
WO (1) WO2006082324A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
EP4335932A2 (fr) 2008-11-07 2024-03-13 Adaptive Biotechnologies Corporation Procédés de surveillance de conditions par analyse de séquence
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US8691510B2 (en) * 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
PT2387627E (pt) 2009-01-15 2016-06-03 Adaptive Biotechnologies Corp Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais
EP3409792B1 (fr) 2009-06-25 2023-09-20 Fred Hutchinson Cancer Center Procédé de mesure de l'immunité adaptative
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
US9279159B2 (en) 2011-10-21 2016-03-08 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
AU2012347460B2 (en) 2011-12-09 2017-05-25 Adaptive Biotechnologies Corporation Diagnosis of lymphoid malignancies and minimal residual disease detection
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
JP6302847B2 (ja) 2012-03-05 2018-03-28 アダプティヴ バイオテクノロジーズ コーポレーション 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定
CN107586832B (zh) 2012-05-08 2021-03-30 适应生物技术公司 用于测量和校准多重pcr反应中的扩增偏倚的组合物和方法
CA2886647A1 (fr) 2012-10-01 2014-04-10 Adaptive Biotechnologies Corporation Evaluation de l'immunocompetence par la diversite des recepteurs de l'immunite adaptative et la caracterisation de la clonalite
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
EP3114240B1 (fr) 2014-03-05 2019-07-24 Adaptive Biotechnologies Corporation Procédés dans lesquels on utilise des molécules synthétiques contenant des randomères
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
ES2777529T3 (es) 2014-04-17 2020-08-05 Adaptive Biotechnologies Corp Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células
EP3212790B1 (fr) 2014-10-29 2020-03-25 Adaptive Biotechnologies Corp. Détection simultanée hautement multiplexée d'acides nucléiques codant pour des hétérodimères de récepteurs de l'immunité adaptative appariés à partir de nombreux échantillons
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
EP3498866A1 (fr) 2014-11-25 2019-06-19 Adaptive Biotechnologies Corp. Caractérisation de la réponse immunitaire adaptative à la vaccination ou l'infection au moyen d'un séquençage de répertoire immunitaire
US11047008B2 (en) 2015-02-24 2021-06-29 Adaptive Biotechnologies Corporation Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
WO2016161273A1 (fr) 2015-04-01 2016-10-06 Adaptive Biotechnologies Corp. Procédé d'identification des récepteurs de lymphocytes t spécifiques à compatibilité humaine pour une cible antigénique
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
CN113640803B (zh) * 2021-09-01 2022-07-22 江西师范大学 一种基于回波强度和回波顶高外推的短时定量降水预报方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235504B1 (en) * 1999-01-11 2001-05-22 The Rockefeller University Methods for identifying genomic equivalent markers and their use in quantitating cells and polynucleotide sequences therein
US20030228586A1 (en) * 1999-06-30 2003-12-11 Rafick-Pierre Sekaly Method for measuring de novo T-cell production in humans
CA2445181A1 (fr) * 2001-04-13 2002-10-24 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procede d'analyse des lymphocytes t par le biais des recepteurs des lymphocytes t d'un organisme

Also Published As

Publication number Publication date
US20080286777A1 (en) 2008-11-20
CA2596389A1 (fr) 2006-08-10
WO2006082324A1 (fr) 2006-08-10
FR2881436A1 (fr) 2006-08-04
JP2008528049A (ja) 2008-07-31
EP1846574A1 (fr) 2007-10-24

Similar Documents

Publication Publication Date Title
FR2881436B1 (fr) Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
HK1199498A1 (en) Voltammetric systems for assaying biological analytes
IL191071A0 (en) Device for detecting analytes in fluid samples
EP1920070A4 (fr) Analyse biologique autonome
EP1954838A4 (fr) Molecules codees permettant de detecter des substances cibles a analyser
EP1954827A4 (fr) Analyse d acide nucléique parallèle rapide
FR2890446B1 (fr) Methode de detection d'interaction intracellulaire entre bio-molecules
FR2881828B1 (fr) Methode de mesure quantitative par immunochromatographie, d'analytes dans un echantillon liquide
EP2047268A4 (fr) Système indicateur pour déterminer la concentration d'analyte
EP1955076A4 (fr) Procede de determination de la qualite d un echantillon biologique
IL187064A0 (en) System for rapid analysis of microbiological materials in liquid samples
ZA200709253B (en) EU/TB-chelate-based fluorescence spectroscopic method for detecting analytes
PL1866651T3 (pl) Sposób analizy próbek krwi
IL187123A0 (en) Automated image analysis
HK1129141A1 (en) Electrochemical biosensor analysis system
GB2422794B (en) Filtration device for biological samples
FR2897873B1 (fr) Procede d'analyse microbiologique rapide.
EP1934602A4 (fr) Procede de detection d'un biomarqueur de stress oxydative dans un echantillon biologique
FR2902441B1 (fr) Procede de determination de la concentration d'acides nucleiques
EP1876441A4 (fr) Procede d'analyse pour echantillon biologique et procede de criblage pour marqueur de maladies
IL182039A0 (en) Micropatterned plate with micro-pallets for addressable biochemical analysis
FI20045456A0 (fi) Lävistystyökalu biologisen näytepalan ottamiseksi
EP1950289A4 (fr) Procede de recueil d'adn dans un echantillon biologique
FR2902883B1 (fr) Procede de detection de microorganisme au sein d'un echantillon
PL2249164T3 (pl) Sposób przetwarzania płynu biologicznego do oznaczania analitu

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20111102