PL1725566T3 - Sposób wytwarzania (1s,2r)-3-[[(4-aminofenylo)sulfonylo](izobutylo)amino]-1-benzylo-2-hydroksypropylokarbaminianu (3r,3as,6ar)-heksahydrofuro-[2,3-b]furan-3-ylu - Google Patents

Sposób wytwarzania (1s,2r)-3-[[(4-aminofenylo)sulfonylo](izobutylo)amino]-1-benzylo-2-hydroksypropylokarbaminianu (3r,3as,6ar)-heksahydrofuro-[2,3-b]furan-3-ylu

Info

Publication number
PL1725566T3
PL1725566T3 PL04805020T PL04805020T PL1725566T3 PL 1725566 T3 PL1725566 T3 PL 1725566T3 PL 04805020 T PL04805020 T PL 04805020T PL 04805020 T PL04805020 T PL 04805020T PL 1725566 T3 PL1725566 T3 PL 1725566T3
Authority
PL
Poland
Prior art keywords
amino
isobutyl
hydroxypropylcarbamate
hexahydrofuro
aminophenyl
Prior art date
Application number
PL04805020T
Other languages
English (en)
Inventor
Nicolaas Martha Felix Goyvaerts
Piet Tom Bert Paul Wigerinck
Hartmut Burghard Zinser
Birgit M Ebert
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34740665&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1725566(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of PL1725566T3 publication Critical patent/PL1725566T3/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL04805020T 2003-12-23 2004-12-23 Sposób wytwarzania (1s,2r)-3-[[(4-aminofenylo)sulfonylo](izobutylo)amino]-1-benzylo-2-hydroksypropylokarbaminianu (3r,3as,6ar)-heksahydrofuro-[2,3-b]furan-3-ylu PL1725566T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP03104949 2003-12-23
US56818304P 2004-05-04 2004-05-04
PCT/EP2004/053692 WO2005063770A1 (en) 2003-12-23 2004-12-23 Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
EP04805020A EP1725566B1 (en) 2003-12-23 2004-12-23 Process for the preparation of (3r,3as,6ar)-hexahydrofuro [2,3-b] furan-3-yl (1s,2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate

Publications (1)

Publication Number Publication Date
PL1725566T3 true PL1725566T3 (pl) 2009-11-30

Family

ID=34740665

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04805020T PL1725566T3 (pl) 2003-12-23 2004-12-23 Sposób wytwarzania (1s,2r)-3-[[(4-aminofenylo)sulfonylo](izobutylo)amino]-1-benzylo-2-hydroksypropylokarbaminianu (3r,3as,6ar)-heksahydrofuro-[2,3-b]furan-3-ylu

Country Status (21)

Country Link
EP (1) EP1725566B1 (pl)
KR (1) KR101192859B1 (pl)
CN (1) CN1898248B (pl)
AT (1) ATE433982T1 (pl)
AU (1) AU2004309122B2 (pl)
BR (1) BRPI0417272B8 (pl)
CA (1) CA2549460C (pl)
CY (1) CY1109379T1 (pl)
DE (1) DE602004021640D1 (pl)
DK (1) DK1725566T3 (pl)
ES (1) ES2328701T3 (pl)
HR (1) HRP20090488T1 (pl)
IL (1) IL174960A (pl)
MX (1) MXPA06007211A (pl)
NO (1) NO337636B1 (pl)
PL (1) PL1725566T3 (pl)
PT (1) PT1725566E (pl)
RU (1) RU2376308C2 (pl)
SI (1) SI1725566T1 (pl)
WO (1) WO2005063770A1 (pl)
ZA (1) ZA200605163B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI432438B (zh) 2005-11-28 2014-04-01 Tibotec Pharm Ltd 作為ｈｉｖ蛋白酶抑制劑之經取代的胺基苯基磺醯胺化合物及衍生物
CN101541775B (zh) * 2006-11-09 2011-12-28 泰博特克药品有限公司 六氢呋喃并[2,3-b]呋喃-3-醇的制备方法
DK2152667T3 (da) * 2007-04-27 2011-05-16 Tibotec Pharm Ltd Fremgangsmåder til fremstilling af N-isobutyl-n-(2-hydroxy-3-amin-4-phenylbutyl)-p-nitrobenzenesulfonylamid-derivater
EP2217548A1 (en) * 2007-10-26 2010-08-18 Concert Pharmaceuticals Inc. Deuterated darunavir
US8592487B2 (en) 2007-10-26 2013-11-26 Concert Pharmaceuticals, Inc. Deuterated darunavir
TWI482775B (zh) 2008-09-01 2015-05-01 Tibotec Pharm Ltd 用於製備（３ｒ，３ａｓ，６ａｒ）－六氫呋喃并〔２，３－ｂ〕呋喃－３－基（１ｓ，２ｒ）－３－〔〔（４－胺基苯基）磺醯基〕（異丁基）胺基〕－１－苯甲基－２－羥基丙基胺基甲酸酯之方法
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
US8853413B2 (en) * 2009-05-13 2014-10-07 Meiji Seika Pharma Co., Ltd. Process for producing pyripyropene derivatives
DK2477992T3 (en) 2009-09-17 2017-03-27 Mylan Laboratories Ltd PROCEDURES FOR PREPARING DARUNAVIR AND ITS AMORPHIC FORM
EP2521728B1 (en) 2010-01-05 2016-09-07 Cipla Limited Crystalline darunavir hydrate and process for preparation thereof
CN102725295A (zh) 2010-01-28 2012-10-10 Mapi医药公司 制备达芦那韦和达芦那韦中间体的方法
CN102584844B (zh) * 2011-01-11 2016-04-13 浙江九洲药业股份有限公司 一种达芦那韦晶型及其制备方法
ES2969589T3 (es) 2012-07-24 2024-05-21 Laurus Labs Ltd Solvato de Propionato de Darunavir
CN103893178B (zh) * 2014-03-19 2016-06-01 中山大学 苯-磺酰胺类化合物在制备抗hiv-1病毒药物中的应用
US20160075643A1 (en) * 2014-09-16 2016-03-17 Zcl Chemicals Limited Novel process to prepare intermediates of hiv-protease inhibitors thereof
US10633390B2 (en) * 2015-06-25 2020-04-28 Msn Laboratories Private Limited Process for the preparation of [(1S,2R)-3-[[(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3R,3AS,6AR)hexahydro furo [2,3-B]furan-3-YL ester and its amorphous form
ES2881949T3 (es) 2016-10-27 2021-11-30 Gilead Sciences Inc Forma cristalina de base libre de darunavir
EP3541819B1 (en) * 2016-11-17 2020-12-09 Janssen Sciences Ireland Unlimited Company A simplified procedure for the preparation of darunavir
CN118026896A (zh) * 2020-12-30 2024-05-14 上海飞腾医药科技有限公司 抗hiv类药物中间体晶体的生长方法和所得晶体
CN113896658A (zh) * 2021-09-24 2022-01-07 上药康丽（常州）药业有限公司 一种利用微通道反应器合成地瑞那韦中间体的方法

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ATE382041T1 (de) 1995-01-20 2008-01-15 Searle Llc Bis-sulfonamid-hydroxyethylamino-derivate als inhibitoren retroviraler proteasen
CA2186483A1 (en) 1995-02-03 1996-08-08 Akira Nishiyama Processes for producing .alpha.-halo ketones, .alpha.-halohydrins and epoxides
US5756533A (en) 1995-03-10 1998-05-26 G.D. Searle & Co. Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5705500A (en) 1995-03-10 1998-01-06 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
ES2190793T3 (es) 1995-03-10 2003-08-16 Searle & Co Inhibidores de proteasas retrovirales de heterociclocarbonil aminoacido hidroxietilamino sulfonamida.
US6150556A (en) 1995-03-10 2000-11-21 G. D. Dearle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
DE60029517T2 (de) 1999-01-29 2006-11-23 Kaneka Corp. VERFAHREN ZUR HERSTELLUNG VON threo-1,2-EPOXY-3-AMINO-4-PHENYLBUTAN-DERIVATEN
US6764545B2 (en) 2000-12-12 2004-07-20 Ajinomoto Co., Inc. Production method of epoxide crystal
PL209029B1 (pl) 2001-05-11 2011-07-29 Tibotec Pharm Ltd Pochodne 2-aminobenzoksazolo-sulfonamidów jako inhibitory proteazy HIV, oraz kompozycje zawierające te związki
EP1466896A4 (en) * 2001-12-28 2005-01-26 Ajinomoto Kk PROCESS FOR PRODUCING A CRYSTAL OF A BENZENESULFONAMIDE DERIVATIVE, AND A NEW CRYSTAL OF AN INTERMEDIATE PRODUCT OF SAID DERIVATIVE AND METHOD FOR PRODUCING THE SAME

Also Published As

Publication number Publication date
PT1725566E (pt) 2009-09-16
AU2004309122B2 (en) 2011-07-21
CA2549460A1 (en) 2005-07-14
ES2328701T3 (es) 2009-11-17
BRPI0417272B8 (pt) 2021-05-25
ZA200605163B (en) 2007-12-27
KR101192859B1 (ko) 2012-10-19
DE602004021640D1 (de) 2009-07-30
AU2004309122A1 (en) 2005-07-14
IL174960A (en) 2011-06-30
BRPI0417272A (pt) 2007-03-27
MXPA06007211A (es) 2006-08-18
CN1898248A (zh) 2007-01-17
EP1725566B1 (en) 2009-06-17
WO2005063770A1 (en) 2005-07-14
NO337636B1 (no) 2016-05-23
IL174960A0 (en) 2006-08-20
ATE433982T1 (de) 2009-07-15
SI1725566T1 (sl) 2009-12-31
RU2006126670A (ru) 2008-01-27
HRP20090488T1 (en) 2009-10-31
RU2376308C2 (ru) 2009-12-20
CY1109379T1 (el) 2014-07-02
KR20060123740A (ko) 2006-12-04
NO20063401L (no) 2006-07-21
EP1725566A1 (en) 2006-11-29
CA2549460C (en) 2014-08-05
DK1725566T3 (da) 2009-10-05
CN1898248B (zh) 2011-08-17
BRPI0417272B1 (pt) 2020-08-18

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