PL148572B1 - Method of obtaining /4s/-6-fluoro-spiro-/chromano-4,4'-imidazolidin/-dione-2',5' or its /2r/-methyl derivative - Google Patents
Method of obtaining /4s/-6-fluoro-spiro-/chromano-4,4'-imidazolidin/-dione-2',5' or its /2r/-methyl derivative Download PDFInfo
- Publication number
- PL148572B1 PL148572B1 PL1985255065A PL25506585A PL148572B1 PL 148572 B1 PL148572 B1 PL 148572B1 PL 1985255065 A PL1985255065 A PL 1985255065A PL 25506585 A PL25506585 A PL 25506585A PL 148572 B1 PL148572 B1 PL 148572B1
- Authority
- PL
- Poland
- Prior art keywords
- methyl
- acid
- spiro
- fluoro
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Pens And Brushes (AREA)
- Coloring (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
- Indole Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64200884A | 1984-08-20 | 1984-08-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL255065A1 PL255065A1 (en) | 1986-11-04 |
| PL148572B1 true PL148572B1 (en) | 1989-10-31 |
Family
ID=24574782
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1985255065A PL148572B1 (en) | 1984-08-20 | 1985-08-19 | Method of obtaining /4s/-6-fluoro-spiro-/chromano-4,4'-imidazolidin/-dione-2',5' or its /2r/-methyl derivative |
| PL1985260564A PL147253B1 (en) | 1984-08-20 | 1985-08-19 | Method of obtaining 4-amino-6-fluorochromanocarboxylic-4 acid or its /2r/ methyl derivative |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1985260564A PL147253B1 (en) | 1984-08-20 | 1985-08-19 | Method of obtaining 4-amino-6-fluorochromanocarboxylic-4 acid or its /2r/ methyl derivative |
Country Status (22)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4952694A (en) * | 1988-07-27 | 1990-08-28 | Pfizer Inc. | Novel resolution process for racemic spiro-hydantoins |
| US5006657A (en) * | 1988-07-27 | 1991-04-09 | Pfizer Inc. | Intermediates in a resolution process for racemic spiro hydantoins |
| US5151544A (en) * | 1990-05-25 | 1992-09-29 | Alcon Laboratories, Inc. | Intermediates in the preparation of chiral spirofluorenehydantoins |
| US5206367A (en) * | 1992-02-18 | 1993-04-27 | Pfizer Inc. | Preparation of optically active spiro-hydantoins |
| US5508466A (en) * | 1994-04-13 | 1996-04-16 | G.D. Searle & Co. | Synthesis of N-protected-α-substituted-glycine racemic esters by zinc-mediated addition of organic halide to glycine cation equivalent |
| EP2957556B1 (en) * | 2013-02-12 | 2020-01-15 | Osaka University | Aromatic amino acid derivative and positron emission tomography (pet) probe using the same |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3878043A (en) * | 1973-01-02 | 1975-04-15 | Univ Southern Illinois | Method for preparing L-dopa and novels compounds useful therein |
| DE2336718A1 (de) * | 1973-07-19 | 1975-02-06 | Basf Ag | Verfahren zur herstellung von substituierten oxazolinon-(5)-verbindungen |
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| DE2807286A1 (de) * | 1978-02-21 | 1979-08-23 | Bayer Ag | Stereoselektive spaltung von phenylglycinderivaten und 4-hydroxyphenylglycinderivaten mit enzymharzen |
| US4267342A (en) * | 1978-08-21 | 1981-05-12 | Pfizer Inc. | Spiro-oxazolidindiones |
| US4262092A (en) * | 1979-05-08 | 1981-04-14 | Ethyl Corporation | Process for producing N-acyl-D-phenylalanine ester |
| DE2927534A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung |
| DE2927535A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Stereoselektive spaltung von phenylglycinderivaten mit enzymharzen |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| GB2098212B (en) * | 1981-05-12 | 1984-11-14 | Ici Plc | Process for preparing 1'-substituted-spiro(imidazolidine)-4,3'-indoline-2,2',5-triones |
| US4435578A (en) * | 1982-11-10 | 1984-03-06 | Pfizer Inc. | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
| US4474967A (en) * | 1983-04-27 | 1984-10-02 | Pfizer Inc. | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione |
| US4464380A (en) * | 1983-05-25 | 1984-08-07 | Pfizer Inc. | Imidazolidinedione derivatives |
-
1985
- 1985-08-13 AT AT85305724T patent/ATE37371T1/de not_active IP Right Cessation
- 1985-08-13 EP EP85305724A patent/EP0172719B1/en not_active Expired
- 1985-08-13 DE DE8585305724T patent/DE3565105D1/de not_active Expired
- 1985-08-16 GR GR851993A patent/GR851993B/el unknown
- 1985-08-16 JP JP60180396A patent/JPS6157588A/ja active Granted
- 1985-08-16 NZ NZ213128A patent/NZ213128A/en unknown
- 1985-08-17 HU HU864033A patent/HU201042B/hu not_active IP Right Cessation
- 1985-08-17 HU HU853185A patent/HU193127B/hu not_active IP Right Cessation
- 1985-08-17 HU HU87630A patent/HU194857B/hu not_active IP Right Cessation
- 1985-08-19 NO NO853254A patent/NO853254L/no unknown
- 1985-08-19 ZA ZA856267A patent/ZA856267B/xx unknown
- 1985-08-19 PL PL1985255065A patent/PL148572B1/pl unknown
- 1985-08-19 EG EG516/85A patent/EG17060A/xx active
- 1985-08-19 FI FI853183A patent/FI853183A7/fi not_active Application Discontinuation
- 1985-08-19 DD DD85279813A patent/DD240207A5/de not_active IP Right Cessation
- 1985-08-19 PL PL1985260564A patent/PL147253B1/pl unknown
- 1985-08-19 IL IL76131A patent/IL76131A/xx unknown
- 1985-08-19 DD DD85295403A patent/DD254005A5/de not_active IP Right Cessation
- 1985-08-19 AU AU46414/85A patent/AU556793B2/en not_active Ceased
- 1985-08-19 DK DK374985A patent/DK374985A/da not_active Application Discontinuation
- 1985-08-19 KR KR1019850005969A patent/KR870000628B1/ko not_active Expired
- 1985-08-19 PT PT80985A patent/PT80985B/pt not_active IP Right Cessation
- 1985-08-19 YU YU1319/85A patent/YU43879B/xx unknown
- 1985-08-20 PH PH32670A patent/PH26782A/en unknown
- 1985-08-20 ES ES546294A patent/ES8700259A1/es not_active Expired
-
1986
- 1986-03-31 US US06/846,383 patent/US4716113A/en not_active Expired - Lifetime
-
1988
- 1988-04-26 JP JP63103727A patent/JPS63290873A/ja active Pending
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