ATE37371T1 - Verfahren zur herstellung asymmetrischer hydantoine. - Google Patents

Verfahren zur herstellung asymmetrischer hydantoine.

Info

Publication number
ATE37371T1
ATE37371T1 AT85305724T AT85305724T ATE37371T1 AT E37371 T1 ATE37371 T1 AT E37371T1 AT 85305724 T AT85305724 T AT 85305724T AT 85305724 T AT85305724 T AT 85305724T AT E37371 T1 ATE37371 T1 AT E37371T1
Authority
AT
Austria
Prior art keywords
spiro
methyl
compound
acid
derivative
Prior art date
Application number
AT85305724T
Other languages
English (en)
Inventor
Frank J Urban
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE37371T1 publication Critical patent/ATE37371T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pens And Brushes (AREA)
  • Coloring (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
AT85305724T 1984-08-20 1985-08-13 Verfahren zur herstellung asymmetrischer hydantoine. ATE37371T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64200884A 1984-08-20 1984-08-20

Publications (1)

Publication Number Publication Date
ATE37371T1 true ATE37371T1 (de) 1988-10-15

Family

ID=24574782

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85305724T ATE37371T1 (de) 1984-08-20 1985-08-13 Verfahren zur herstellung asymmetrischer hydantoine.

Country Status (22)

Country Link
US (1) US4716113A (de)
EP (1) EP0172719B1 (de)
JP (2) JPS6157588A (de)
KR (1) KR870000628B1 (de)
AT (1) ATE37371T1 (de)
AU (1) AU556793B2 (de)
DD (2) DD254005A5 (de)
DE (1) DE3565105D1 (de)
DK (1) DK374985A (de)
EG (1) EG17060A (de)
ES (1) ES8700259A1 (de)
FI (1) FI853183L (de)
GR (1) GR851993B (de)
HU (3) HU201042B (de)
IL (1) IL76131A (de)
NO (1) NO853254L (de)
NZ (1) NZ213128A (de)
PH (1) PH26782A (de)
PL (2) PL147253B1 (de)
PT (1) PT80985B (de)
YU (1) YU43879B (de)
ZA (1) ZA856267B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006657A (en) * 1988-07-27 1991-04-09 Pfizer Inc. Intermediates in a resolution process for racemic spiro hydantoins
US4952694A (en) * 1988-07-27 1990-08-28 Pfizer Inc. Novel resolution process for racemic spiro-hydantoins
US5151544A (en) * 1990-05-25 1992-09-29 Alcon Laboratories, Inc. Intermediates in the preparation of chiral spirofluorenehydantoins
US5206367A (en) * 1992-02-18 1993-04-27 Pfizer Inc. Preparation of optically active spiro-hydantoins
US5508466A (en) * 1994-04-13 1996-04-16 G.D. Searle & Co. Synthesis of N-protected-α-substituted-glycine racemic esters by zinc-mediated addition of organic halide to glycine cation equivalent
WO2014126071A1 (ja) * 2013-02-12 2014-08-21 国立大学法人大阪大学 芳香族アミノ酸誘導体およびそれを用いるｐｅｔプローブ

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878043A (en) * 1973-01-02 1975-04-15 Univ Southern Illinois Method for preparing L-dopa and novels compounds useful therein
DE2336718A1 (de) * 1973-07-19 1975-02-06 Basf Ag Verfahren zur herstellung von substituierten oxazolinon-(5)-verbindungen
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
DE2807286A1 (de) * 1978-02-21 1979-08-23 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten und 4-hydroxyphenylglycinderivaten mit enzymharzen
US4267342A (en) * 1978-08-21 1981-05-12 Pfizer Inc. Spiro-oxazolidindiones
US4262092A (en) * 1979-05-08 1981-04-14 Ethyl Corporation Process for producing N-acyl-D-phenylalanine ester
DE2927535A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Stereoselektive spaltung von phenylglycinderivaten mit enzymharzen
DE2927534A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
GB2098212B (en) * 1981-05-12 1984-11-14 Ici Plc Process for preparing 1'-substituted-spiro(imidazolidine)-4,3'-indoline-2,2',5-triones
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4474967A (en) * 1983-04-27 1984-10-02 Pfizer Inc. 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives

Also Published As

Publication number Publication date
PT80985A (en) 1985-09-01
HUT46316A (en) 1988-10-28
ES8700259A1 (es) 1986-10-01
FI853183L (fi) 1986-02-21
EP0172719B1 (de) 1988-09-21
IL76131A0 (en) 1985-12-31
HU201042B (en) 1990-09-28
US4716113A (en) 1987-12-29
IL76131A (en) 1989-01-31
YU43879B (en) 1989-12-31
HU194857B (en) 1988-03-28
JPS6157588A (ja) 1986-03-24
JPS63290873A (ja) 1988-11-28
PT80985B (pt) 1987-12-30
DD240207A5 (de) 1986-10-22
PH26782A (en) 1992-10-13
PL255065A1 (en) 1986-11-04
PL147253B1 (en) 1989-05-31
JPS6362512B2 (de) 1988-12-02
AU556793B2 (en) 1986-11-20
PL260564A1 (en) 1987-02-09
KR870000628B1 (ko) 1987-03-26
NZ213128A (en) 1988-02-29
FI853183A0 (fi) 1985-08-19
EG17060A (en) 1991-03-30
DK374985A (da) 1986-02-21
AU4641485A (en) 1986-02-27
YU131985A (en) 1988-04-30
DD254005A5 (de) 1988-02-10
ES546294A0 (es) 1986-10-01
GR851993B (de) 1985-12-17
DK374985D0 (da) 1985-08-19
HUT39745A (en) 1986-10-29
EP0172719A1 (de) 1986-02-26
ZA856267B (en) 1987-04-29
HUT43577A (en) 1987-11-30
HU193127B (en) 1987-08-28
PL148572B1 (en) 1989-10-31
DE3565105D1 (en) 1988-10-27
KR870002142A (ko) 1987-03-30
NO853254L (no) 1986-02-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee