PL147386B1 - Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide - Google Patents

Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide Download PDF

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Publication number
PL147386B1
PL147386B1 PL1985257385A PL25738585A PL147386B1 PL 147386 B1 PL147386 B1 PL 147386B1 PL 1985257385 A PL1985257385 A PL 1985257385A PL 25738585 A PL25738585 A PL 25738585A PL 147386 B1 PL147386 B1 PL 147386B1
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Poland
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radical
denotes
ethyl
alpha
keto
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PL1985257385A
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English (en)
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PL257385A1 (en
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Ucb Sa
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10560974&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL147386(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of PL257385A1 publication Critical patent/PL257385A1/xx
Publication of PL147386B1 publication Critical patent/PL147386B1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Detergent Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Seasonings (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)

Claims (1)

Zastrzezenie patentowe Sposób wytwarzania /S/-o(-etylo-2-keto-1-pirolidynoacetamidu, znamienny tym ze cyklizuje sie, w obojetnym rozpuszczalniku i w obecnosci substancji o charakterze zasa¬ dowym, /S/-2-aminobutanamid o wzorze Z-CHgCHg-Y-NHCH/CgHc/CONHg, w którym X oznaoza rodnik Z00C- lub HalCH2-, w którym Z oznacza rodnik alkilowy 0
1 - 4 atomaoh wegla a Hal oznaoza atom ohlorowca, zas Y oznacza rodnik -CHp- lub -^0-, z tym, ze gdy X oznacza rodnik Z00C- to wówczas Y oznaoza rodnik -CHg a gdy X oznaoza rodnik HalCHp- to wówczas Y oznaoza rod¬ nik -C0-. Pracownia Poligraficzna UP PRL. Naklad 100 egz. Cena 400 zl
PL1985257385A 1984-05-15 1985-05-14 Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide PL147386B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848412357A GB8412357D0 (en) 1984-05-15 1984-05-15 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
PL257385A1 PL257385A1 (en) 1986-10-07
PL147386B1 true PL147386B1 (en) 1989-05-31

Family

ID=10560974

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1985253374A PL144346B1 (en) 1984-05-15 1985-05-14 Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide
PL1985257385A PL147386B1 (en) 1984-05-15 1985-05-14 Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL1985253374A PL144346B1 (en) 1984-05-15 1985-05-14 Method of obtaining /s/-alpha-ethyl-2-keto-1-pyrolidinacetamide

Country Status (33)

Country Link
US (3) US4696943A (pl)
EP (1) EP0162036B1 (pl)
JP (1) JPH0629186B2 (pl)
KR (1) KR920003819B1 (pl)
CN (1) CN1015541B (pl)
AT (1) ATE45567T1 (pl)
AU (1) AU574465B2 (pl)
BG (2) BG50156A3 (pl)
CA (1) CA1235129A (pl)
CY (2) CY1567A (pl)
DE (3) DE10199005I2 (pl)
DK (1) DK163501C (pl)
ES (2) ES8608485A1 (pl)
FI (1) FI80673C (pl)
GB (1) GB8412357D0 (pl)
GE (1) GEP20002001B (pl)
GR (1) GR851155B (pl)
HK (1) HK52391A (pl)
IE (1) IE59950B1 (pl)
IL (1) IL75179A (pl)
LT (1) LT2584B (pl)
LU (2) LU90615I2 (pl)
LV (1) LV5233A3 (pl)
MY (2) MY101726A (pl)
NL (1) NL300028I2 (pl)
NO (2) NO164534C (pl)
PL (2) PL144346B1 (pl)
PT (1) PT80460B (pl)
SA (1) SA01210656A (pl)
SG (1) SG80090G (pl)
SU (3) SU1402260A3 (pl)
UA (1) UA6158A1 (pl)
ZA (1) ZA853635B (pl)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
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US12559456B2 (en) 2021-02-03 2026-02-24 Suzhou Brighthope Pharma Tech Co., Ltd Method for preparing levetiracetam and intermediates thereof
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CN113979911A (zh) * 2021-11-12 2022-01-28 汤斌 一种从大鲵肽中提取乙拉西坦的方法
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US20240368080A1 (en) * 2023-05-05 2024-11-07 Suzhou Brighthope Pharmatech Co., Ltd Process for the production of levetiracetam and intermediate thereof
US20240368081A1 (en) * 2023-05-05 2024-11-07 Suzhou Brighthope Pharmatech Co., Ltd Process for the production of levetiracetam and intermediate thereof
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SU1430392A1 (ru) 1988-10-15
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