PL111221B1 - Preparation of 2-/4-substituted piperazinyl-1/-4-aminoguinazolines - Google Patents

Preparation of 2-/4-substituted piperazinyl-1/-4-aminoguinazolines Download PDF

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Publication number
PL111221B1
PL111221B1 PL1977211798A PL21179877A PL111221B1 PL 111221 B1 PL111221 B1 PL 111221B1 PL 1977211798 A PL1977211798 A PL 1977211798A PL 21179877 A PL21179877 A PL 21179877A PL 111221 B1 PL111221 B1 PL 111221B1
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PL
Poland
Prior art keywords
formula
compound
reaction
temperature
compounds
Prior art date
Application number
PL1977211798A
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English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Publication of PL111221B1 publication Critical patent/PL111221B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL1977211798A 1976-06-15 1977-06-15 Preparation of 2-/4-substituted piperazinyl-1/-4-aminoguinazolines PL111221B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (1)

Publication Number Publication Date
PL111221B1 true PL111221B1 (en) 1980-08-30

Family

ID=24796111

Family Applications (3)

Application Number Title Priority Date Filing Date
PL1977198874A PL105558B1 (pl) 1976-06-15 1977-06-15 Sposob wytwarzania 2-/4-podstawionych piperazynylo-1/-4-aminochinazolin
PL1977211798A PL111221B1 (en) 1976-06-15 1977-06-15 Preparation of 2-/4-substituted piperazinyl-1/-4-aminoguinazolines
PL1977211797A PL113012B1 (en) 1976-06-15 1977-06-15 Method of manufacture of 2/4-substituted piperazinyl-1/-4-aminoquinazolines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL1977198874A PL105558B1 (pl) 1976-06-15 1977-06-15 Sposob wytwarzania 2-/4-podstawionych piperazynylo-1/-4-aminochinazolin

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1977211797A PL113012B1 (en) 1976-06-15 1977-06-15 Method of manufacture of 2/4-substituted piperazinyl-1/-4-aminoquinazolines

Country Status (34)

Country Link
JP (1) JPS52153985A (hu)
AR (1) AR218251A1 (hu)
AT (1) AT356115B (hu)
BE (1) BE855656A (hu)
BG (3) BG35748A3 (hu)
CA (1) CA1068698A (hu)
CH (3) CH638203A5 (hu)
CS (1) CS202069B2 (hu)
DD (1) DD131021A5 (hu)
DE (1) DE2725019A1 (hu)
DK (1) DK146625C (hu)
EG (1) EG12922A (hu)
ES (1) ES459364A1 (hu)
FI (1) FI66853C (hu)
FR (1) FR2355015A1 (hu)
GB (1) GB1548856A (hu)
GR (1) GR72288B (hu)
HK (1) HK31481A (hu)
HU (1) HU177883B (hu)
IE (1) IE45423B1 (hu)
IL (1) IL52167A (hu)
LU (1) LU77530A1 (hu)
MY (1) MY8100270A (hu)
NL (1) NL172543C (hu)
NO (1) NO147838C (hu)
NZ (1) NZ184168A (hu)
PH (1) PH22196A (hu)
PL (3) PL105558B1 (hu)
PT (1) PT66617B (hu)
RO (3) RO77308A (hu)
SE (2) SE435380B (hu)
SU (2) SU1033002A3 (hu)
YU (1) YU40164B (hu)
ZA (1) ZA773014B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS536156B2 (hu) * 1972-10-30 1978-03-04
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (hu) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
FI66853B (fi) 1984-08-31
SU946402A3 (ru) 1982-07-23
RO77330A (ro) 1981-06-22
FI771741A (hu) 1977-12-16
EG12922A (en) 1980-03-31
FI66853C (fi) 1984-12-10
ATA386977A (de) 1979-09-15
NL172543C (nl) 1983-09-16
IE45423B1 (en) 1982-08-25
FR2355015A1 (fr) 1978-01-13
NL172543B (nl) 1983-04-18
GR72288B (hu) 1983-10-17
CS202069B2 (en) 1980-12-31
DK240877A (da) 1977-12-16
PH22196A (en) 1988-06-28
LU77530A1 (fr) 1979-03-26
IL52167A0 (en) 1977-07-31
SE435380B (sv) 1984-09-24
PL198874A1 (pl) 1978-04-10
RO73050A (ro) 1981-08-30
NO147838C (no) 1983-06-22
DE2725019A1 (de) 1977-12-22
PL113012B1 (en) 1980-11-29
BG35748A3 (en) 1984-06-15
CA1068698A (en) 1979-12-25
CH638203A5 (en) 1983-09-15
SE8107554L (sv) 1981-12-16
JPS52153985A (en) 1977-12-21
SE7705745L (sv) 1977-12-16
NO147838B (no) 1983-03-14
BE855656A (fr) 1977-12-14
DD131021A5 (de) 1978-05-24
GB1548856A (en) 1979-07-18
DK146625B (da) 1983-11-21
AU2558377A (en) 1978-09-07
IE45423L (en) 1977-12-15
HK31481A (en) 1981-07-10
SU1033002A3 (ru) 1983-07-30
HU177883B (en) 1982-01-28
NZ184168A (en) 1979-08-31
NO771919L (no) 1977-12-16
SE450120B (sv) 1987-06-09
CH638516A5 (en) 1983-09-30
RO77308A (ro) 1981-08-17
JPS5543465B2 (hu) 1980-11-06
YU40164B (en) 1985-08-31
IL52167A (en) 1981-01-30
ZA773014B (en) 1978-04-26
YU132677A (en) 1982-08-31
ES459364A1 (es) 1978-03-16
AT356115B (de) 1980-04-10
CH638517A5 (en) 1983-09-30
NL7705939A (nl) 1977-12-19
PL105558B1 (pl) 1979-10-31
BG35747A3 (en) 1984-06-15
PT66617B (en) 1978-10-27
PT66617A (en) 1977-06-01
AR218251A1 (es) 1980-05-30
DK146625C (da) 1984-06-04
MY8100270A (en) 1981-12-31
BG35594A3 (en) 1984-05-15
FR2355015B1 (hu) 1981-07-24

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