PL110392B1 - Method of producing new derivatives of 9-chloroprednisolone - Google Patents
Method of producing new derivatives of 9-chloroprednisolone Download PDFInfo
- Publication number
- PL110392B1 PL110392B1 PL1977201161A PL20116177A PL110392B1 PL 110392 B1 PL110392 B1 PL 110392B1 PL 1977201161 A PL1977201161 A PL 1977201161A PL 20116177 A PL20116177 A PL 20116177A PL 110392 B1 PL110392 B1 PL 110392B1
- Authority
- PL
- Poland
- Prior art keywords
- dione
- hydroxy
- pregnadiene
- chloro
- butyryloxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2645105A DE2645105C2 (de) | 1976-10-04 | 1976-10-04 | Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat |
| DE19772742982 DE2742982C2 (de) | 1977-09-21 | 1977-09-21 | 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL201161A1 PL201161A1 (pl) | 1979-01-29 |
| PL110392B1 true PL110392B1 (en) | 1980-07-31 |
Family
ID=25770978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1977201161A PL110392B1 (en) | 1976-10-04 | 1977-09-30 | Method of producing new derivatives of 9-chloroprednisolone |
Country Status (21)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2853785A1 (de) * | 1978-12-11 | 1980-06-19 | Schering Ag | Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung |
| JPH0374245A (ja) * | 1989-08-12 | 1991-03-28 | Mk Seiko Co Ltd | 洗車機 |
| PT2552449T (pt) | 2010-03-26 | 2017-06-12 | Galderma Res & Dev | Composições que compreendem brimonidina para o tratamento de eritema |
| AU2012324543B2 (en) | 2011-10-19 | 2017-08-10 | Galderma S.A. | Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors |
| CN106632561A (zh) * | 2016-12-16 | 2017-05-10 | 广州仁恒医药科技股份有限公司 | 一种二氟泼尼酯的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH429716A (de) * | 1961-06-24 | 1967-02-15 | Vismara Francesco Spa | Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden |
| DE2055221A1 (en) * | 1970-11-10 | 1972-05-18 | Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) | 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride |
-
1977
- 1977-09-29 NZ NZ185295A patent/NZ185295A/xx unknown
- 1977-09-30 PL PL1977201161A patent/PL110392B1/pl unknown
- 1977-09-30 IL IL53030A patent/IL53030A/xx unknown
- 1977-09-30 CH CH1199177A patent/CH630098A5/de not_active IP Right Cessation
- 1977-10-03 AT AT703577A patent/AT358202B/de not_active IP Right Cessation
- 1977-10-03 IT IT28201/77A patent/IT1113623B/it active
- 1977-10-03 SE SE7711039A patent/SE431655B/xx not_active IP Right Cessation
- 1977-10-03 NO NO773362A patent/NO148597C/no unknown
- 1977-10-03 LU LU78223A patent/LU78223A1/xx unknown
- 1977-10-03 GB GB40924/77A patent/GB1594852A/en not_active Expired
- 1977-10-03 PT PT67109A patent/PT67109B/pt unknown
- 1977-10-03 HU HU77SCHE624A patent/HU179593B/hu unknown
- 1977-10-03 GR GR54473A patent/GR73041B/el unknown
- 1977-10-03 IE IE2011/77A patent/IE45877B1/en unknown
- 1977-10-04 DK DK438277A patent/DK438277A/da not_active Application Discontinuation
- 1977-10-04 FI FI772922A patent/FI58645C/fi not_active IP Right Cessation
- 1977-10-04 JP JP11940077A patent/JPS5359654A/ja active Granted
- 1977-10-04 ES ES462887A patent/ES462887A1/es not_active Expired
- 1977-10-04 FR FR7729740A patent/FR2366313A1/fr active Granted
- 1977-10-04 SU SU772526300A patent/SU743581A3/ru active
- 1977-10-04 NL NL7710869A patent/NL7710869A/xx not_active Application Discontinuation
-
1978
- 1978-10-13 SU SU782672298A patent/SU751327A3/ru active
-
1981
- 1981-09-08 CH CH579381A patent/CH632278A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579281A patent/CH632772A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579481A patent/CH631997A5/de not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2081205C (en) | Steroids which inhibit angiogenesis | |
| JP4388600B2 (ja) | コルチコイド化合物の硝酸エステル類およびその薬学的使用 | |
| JP3333210B2 (ja) | 新規プレドニソロン誘導体および該化合物を含有する薬剤 | |
| CZ149693A3 (en) | Novel steroids | |
| US5972922A (en) | Steroids which inhibit angiogenesis | |
| US4910192A (en) | Topically active steroidal anti-inflammatory agents | |
| US5801165A (en) | Antiinflammatory, immunosuppressive and antialleric 16, 17-alkylidioxy-steroids | |
| HU190746B (en) | Process for producing 6-alpha-methyl-corticoides and pharmaceutical compositions containing them | |
| PL110392B1 (en) | Method of producing new derivatives of 9-chloroprednisolone | |
| CA1251784A (en) | Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments | |
| US4777165A (en) | 6α, 16β-dimethyl corticoids and their anti-inflammatory use | |
| EP0387091A2 (en) | Steroid diols, processes for their preparation and pharmaceutical compositions thereof | |
| DE3687239T2 (de) | 16,17-acetal-substituierte androstane-17-beta-carbonsaeureester, verfahren zu deren herstellung und pharmazeutische praeparate die diese enthalten. | |
| JPH0419238B2 (enrdf_load_stackoverflow) | ||
| US4232013A (en) | 16,17-Pyrazolino- and 16,17-isopyrazolino-1,4-pregnadiene derivatives | |
| GB1603281A (en) | Derivatives of 9-fluoroprednisolone | |
| DE2645105C2 (de) | Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat | |
| CS244663B2 (cs) | Způsob výroby nových derivátů 9-chlorprednisolonu | |
| EP0019763B1 (de) | Neue Kortikoide, ihre Herstellung und Verwendung | |
| CS244662B2 (cs) | Způsob výroby nových derivátů 9-chlorprednisolonu | |
| DE2809732A1 (de) | Neue derivate des 9-fluorprednisolons | |
| AT373604B (de) | Verfahren zur herstellung von neuen derivaten des 9-chlorprednisolons | |
| CS199512B2 (cs) | Způsob výroby kortikoidfi | |
| CS207756B2 (cs) | Způsob výroby v poloze 17 substituovaných 11β-bydroxysteroidů pregnanové řady | |
| HU181970B (en) | Process for preparing new derivatives of 9alpha-fluoro-prednisolone |