ES462887A1 - Procedimiento para la preparacion de nuevos derivados de la 9-cloroprednisolana. - Google Patents

Procedimiento para la preparacion de nuevos derivados de la 9-cloroprednisolana.

Info

Publication number
ES462887A1
ES462887A1 ES462887A ES462887A ES462887A1 ES 462887 A1 ES462887 A1 ES 462887A1 ES 462887 A ES462887 A ES 462887A ES 462887 A ES462887 A ES 462887A ES 462887 A1 ES462887 A1 ES 462887A1
Authority
ES
Spain
Prior art keywords
group
chloroprednisolone
carbon atoms
derivatives
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462887A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of ES462887A1 publication Critical patent/ES462887A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES462887A 1976-10-04 1977-10-04 Procedimiento para la preparacion de nuevos derivados de la 9-cloroprednisolana. Expired ES462887A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (1)

Publication Number Publication Date
ES462887A1 true ES462887A1 (es) 1978-12-16

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462887A Expired ES462887A1 (es) 1976-10-04 1977-10-04 Procedimiento para la preparacion de nuevos derivados de la 9-cloroprednisolana.

Country Status (21)

Country Link
JP (1) JPS5359654A (enrdf_load_stackoverflow)
AT (1) AT358202B (enrdf_load_stackoverflow)
CH (4) CH630098A5 (enrdf_load_stackoverflow)
DK (1) DK438277A (enrdf_load_stackoverflow)
ES (1) ES462887A1 (enrdf_load_stackoverflow)
FI (1) FI58645C (enrdf_load_stackoverflow)
FR (1) FR2366313A1 (enrdf_load_stackoverflow)
GB (1) GB1594852A (enrdf_load_stackoverflow)
GR (1) GR73041B (enrdf_load_stackoverflow)
HU (1) HU179593B (enrdf_load_stackoverflow)
IE (1) IE45877B1 (enrdf_load_stackoverflow)
IL (1) IL53030A (enrdf_load_stackoverflow)
IT (1) IT1113623B (enrdf_load_stackoverflow)
LU (1) LU78223A1 (enrdf_load_stackoverflow)
NL (1) NL7710869A (enrdf_load_stackoverflow)
NO (1) NO148597C (enrdf_load_stackoverflow)
NZ (1) NZ185295A (enrdf_load_stackoverflow)
PL (1) PL110392B1 (enrdf_load_stackoverflow)
PT (1) PT67109B (enrdf_load_stackoverflow)
SE (1) SE431655B (enrdf_load_stackoverflow)
SU (2) SU743581A3 (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
PT2552449T (pt) 2010-03-26 2017-06-12 Galderma Res & Dev Composições que compreendem brimonidina para o tratamento de eritema
AU2012324543B2 (en) 2011-10-19 2017-08-10 Galderma S.A. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH429716A (de) * 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
NO148597B (no) 1983-08-01
IT1113623B (it) 1986-01-20
NL7710869A (nl) 1978-04-06
JPS6129960B2 (enrdf_load_stackoverflow) 1986-07-10
FR2366313A1 (fr) 1978-04-28
PT67109B (de) 1979-03-14
CH630098A5 (en) 1982-05-28
CH631997A5 (en) 1982-09-15
PL110392B1 (en) 1980-07-31
NO148597C (no) 1983-11-09
IL53030A (en) 1982-11-30
FR2366313B1 (enrdf_load_stackoverflow) 1980-02-01
GR73041B (enrdf_load_stackoverflow) 1984-01-26
NZ185295A (en) 1980-04-28
AT358202B (de) 1980-08-25
GB1594852A (en) 1981-08-05
JPS5359654A (en) 1978-05-29
ATA703577A (de) 1980-01-15
IE45877B1 (en) 1982-12-15
FI772922A7 (fi) 1978-04-05
SU743581A3 (ru) 1980-06-25
IE45877L (en) 1978-04-04
HU179593B (en) 1982-11-29
CH632278A5 (en) 1982-09-30
CH632772A5 (en) 1982-10-29
SE7711039L (sv) 1978-04-05
PL201161A1 (pl) 1979-01-29
PT67109A (de) 1977-11-01
SU751327A3 (ru) 1980-07-23
LU78223A1 (enrdf_load_stackoverflow) 1978-02-01
DK438277A (da) 1978-04-05
FI58645B (fi) 1980-11-28
NO773362L (no) 1978-04-05
SE431655B (sv) 1984-02-20
FI58645C (fi) 1981-03-10
IL53030A0 (en) 1977-11-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001