ES527319A0 - Un procedimiento para la preparacion de derivados de fenil-piperazina - Google Patents

Un procedimiento para la preparacion de derivados de fenil-piperazina

Info

Publication number
ES527319A0
ES527319A0 ES527319A ES527319A ES527319A0 ES 527319 A0 ES527319 A0 ES 527319A0 ES 527319 A ES527319 A ES 527319A ES 527319 A ES527319 A ES 527319A ES 527319 A0 ES527319 A0 ES 527319A0
Authority
ES
Spain
Prior art keywords
group
phenyl
procedure
preparation
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES527319A
Other languages
English (en)
Other versions
ES8504778A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES8504778A1 publication Critical patent/ES8504778A1/es
Publication of ES527319A0 publication Critical patent/ES527319A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Paper (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
ES527319A 1982-03-17 1983-11-16 Un procedimiento para la preparacion de derivados de fenil-piperazina Granted ES527319A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57040904A JPS58159480A (ja) 1982-03-17 1982-03-17 新規なフエニルピペラジン誘導体

Publications (2)

Publication Number Publication Date
ES8504778A1 ES8504778A1 (es) 1985-05-01
ES527319A0 true ES527319A0 (es) 1985-05-01

Family

ID=12593492

Family Applications (3)

Application Number Title Priority Date Filing Date
ES520693A Granted ES520693A0 (es) 1982-03-17 1983-03-16 Un procedimiento para la preparacion de derivados de fenilpiperazina.
ES527318A Granted ES527318A0 (es) 1982-03-17 1983-11-16 Un procedimiento para la preparacion de derivados de fenilpiperazina
ES527319A Granted ES527319A0 (es) 1982-03-17 1983-11-16 Un procedimiento para la preparacion de derivados de fenil-piperazina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES520693A Granted ES520693A0 (es) 1982-03-17 1983-03-16 Un procedimiento para la preparacion de derivados de fenilpiperazina.
ES527318A Granted ES527318A0 (es) 1982-03-17 1983-11-16 Un procedimiento para la preparacion de derivados de fenilpiperazina

Country Status (12)

Country Link
US (1) US4578465A (es)
EP (1) EP0089065B1 (es)
JP (1) JPS58159480A (es)
KR (1) KR900004125B1 (es)
AT (1) ATE27817T1 (es)
CA (1) CA1248102A (es)
DE (2) DE3372095D1 (es)
DK (1) DK156064C (es)
ES (3) ES520693A0 (es)
FI (1) FI77456C (es)
MX (1) MX7157E (es)
ZA (1) ZA831674B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608274A (ja) * 1983-06-27 1985-01-17 Fujisawa Pharmaceut Co Ltd 新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
JPS60169467A (ja) * 1984-02-10 1985-09-02 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
US4711883A (en) * 1985-09-30 1987-12-08 Ortho Pharmaceutical Corporation Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
GB8524663D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives
JPS62135464A (ja) * 1985-12-10 1987-06-18 Nippon Kayaku Co Ltd フエニルピペラジン誘導体
US4670560A (en) * 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
IL90879A0 (en) * 1988-09-02 1990-02-09 Janssen Pharmaceutica Nv 3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them
US5160727A (en) * 1990-02-13 1992-11-03 Warner-Lambert Company Tumor cell sensitization method using quinazolinedione derivatives
HUE031053T2 (en) * 2009-02-26 2017-06-28 Reviva Pharmaceuticals Inc Preparations, synthesis and methods of application of arylpiperazine derivatives
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
KR102132078B1 (ko) * 2018-09-20 2020-07-08 원광대학교산학협력단 방향족 화합물, 아민 및 친핵체를 이용한 3가지 성분 반응으로 1-에틸-4-페닐피페라진 유도체를 제조하는 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274194A (en) * 1963-03-29 1966-09-20 Miles Lab Quinazolinedione derivatives
US3322766A (en) * 1964-11-13 1967-05-30 Shulton Inc 3-beta-(4-pyridyl) ethyl-2, 3-dihydro-4(1h)-quinazolinones
AT269143B (de) * 1966-06-30 1969-03-10 Miles Lab Verfahren zur Herstellung von neuen Chinazolindionderivaten und ihrer Säureadditionssalze bzw. ihrer entsprechenden Piperaziniumverbindungen
CA933160A (en) * 1968-02-29 1973-09-04 Wallace And Tiernan Inc. Process for preparing diuretic 2,4-quinazolinediones and the products obtained thereby
DE1934037A1 (de) * 1969-07-04 1971-01-07 Cassella Farbwerke Mainkur Ag Basisch substituierte Derivate des 2,4-(1H,3H)-Chinazolindions
US3726979A (en) * 1971-04-09 1973-04-10 E Hong Method of producing serotonin antagonism
US3819630A (en) * 1972-08-21 1974-06-25 R Parcell 3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production
US3879393A (en) * 1973-06-18 1975-04-22 Miles Lab Derivatives of 1,3-disubstituted 2,4(1h,3h)-quinazolinediones
DE3172006D1 (en) * 1980-05-22 1985-10-03 Masayuki Ishikawa Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof

Also Published As

Publication number Publication date
EP0089065A3 (en) 1984-05-23
JPS58159480A (ja) 1983-09-21
EP0089065A2 (en) 1983-09-21
ES8504778A1 (es) 1985-05-01
DK120483D0 (da) 1983-03-15
ES8404347A1 (es) 1984-05-01
JPH033669B2 (es) 1991-01-21
DE89065T1 (de) 1985-04-11
DE3372095D1 (en) 1987-07-23
FI830893A0 (fi) 1983-03-17
FI77456C (fi) 1989-03-10
FI830893L (fi) 1983-09-18
MX7157E (es) 1987-11-27
ATE27817T1 (de) 1987-07-15
ES8504777A1 (es) 1985-05-01
US4578465A (en) 1986-03-25
EP0089065B1 (en) 1987-06-16
ES520693A0 (es) 1984-05-01
KR840004104A (ko) 1984-10-06
CA1248102A (en) 1989-01-03
ZA831674B (en) 1984-04-25
KR900004125B1 (ko) 1990-06-16
DK156064C (da) 1989-11-06
DK120483A (da) 1983-09-18
FI77456B (fi) 1988-11-30
ES527318A0 (es) 1985-05-01
DK156064B (da) 1989-06-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401