ZA831674B - Phenylpiperazine derivatives and process for producing the same - Google Patents

Phenylpiperazine derivatives and process for producing the same

Info

Publication number
ZA831674B
ZA831674B ZA831674A ZA831674A ZA831674B ZA 831674 B ZA831674 B ZA 831674B ZA 831674 A ZA831674 A ZA 831674A ZA 831674 A ZA831674 A ZA 831674A ZA 831674 B ZA831674 B ZA 831674B
Authority
ZA
South Africa
Prior art keywords
group
producing
same
derivatives
sub
Prior art date
Application number
ZA831674A
Other languages
English (en)
Inventor
Hiroyuki Nagano
Mitiro Takagi
Noboru Kubodera
Isao Matsunaga
Hiroyuki Nabata
Yasuhiro Ohba
Kazushige Sakai
Shun-Ichi Hata
Yasumi Uchida
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ZA831674B publication Critical patent/ZA831674B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Paper (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
ZA831674A 1982-03-17 1983-03-11 Phenylpiperazine derivatives and process for producing the same ZA831674B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57040904A JPS58159480A (ja) 1982-03-17 1982-03-17 新規なフエニルピペラジン誘導体

Publications (1)

Publication Number Publication Date
ZA831674B true ZA831674B (en) 1984-04-25

Family

ID=12593492

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA831674A ZA831674B (en) 1982-03-17 1983-03-11 Phenylpiperazine derivatives and process for producing the same

Country Status (12)

Country Link
US (1) US4578465A (es)
EP (1) EP0089065B1 (es)
JP (1) JPS58159480A (es)
KR (1) KR900004125B1 (es)
AT (1) ATE27817T1 (es)
CA (1) CA1248102A (es)
DE (2) DE89065T1 (es)
DK (1) DK156064C (es)
ES (3) ES8404347A1 (es)
FI (1) FI77456C (es)
MX (1) MX7157E (es)
ZA (1) ZA831674B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608274A (ja) * 1983-06-27 1985-01-17 Fujisawa Pharmaceut Co Ltd 新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
JPS60169467A (ja) * 1984-02-10 1985-09-02 Chugai Pharmaceut Co Ltd 新規なフエニルピペラジン誘導体
US4711883A (en) * 1985-09-30 1987-12-08 Ortho Pharmaceutical Corporation Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
GB8524663D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives
JPS62135464A (ja) * 1985-12-10 1987-06-18 Nippon Kayaku Co Ltd フエニルピペラジン誘導体
US4670560A (en) * 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
IL90879A0 (en) * 1988-09-02 1990-02-09 Janssen Pharmaceutica Nv 3-piperidinyl-indazole derivatives,their preparation and antihypertensive compositions containing them
US5160727A (en) * 1990-02-13 1992-11-03 Warner-Lambert Company Tumor cell sensitization method using quinazolinedione derivatives
KR101705727B1 (ko) * 2009-02-26 2017-02-10 레비바 파마슈티칼스, 아이엔씨. 아릴피페라진 유도체의 조성물, 합성, 및 사용 방법
BRPI1003506B1 (pt) * 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
KR102132078B1 (ko) * 2018-09-20 2020-07-08 원광대학교산학협력단 방향족 화합물, 아민 및 친핵체를 이용한 3가지 성분 반응으로 1-에틸-4-페닐피페라진 유도체를 제조하는 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274194A (en) * 1963-03-29 1966-09-20 Miles Lab Quinazolinedione derivatives
US3322766A (en) * 1964-11-13 1967-05-30 Shulton Inc 3-beta-(4-pyridyl) ethyl-2, 3-dihydro-4(1h)-quinazolinones
AT269143B (de) * 1966-06-30 1969-03-10 Miles Lab Verfahren zur Herstellung von neuen Chinazolindionderivaten und ihrer Säureadditionssalze bzw. ihrer entsprechenden Piperaziniumverbindungen
GB1227936A (es) * 1968-02-29 1971-04-15
DE1934037A1 (de) * 1969-07-04 1971-01-07 Cassella Farbwerke Mainkur Ag Basisch substituierte Derivate des 2,4-(1H,3H)-Chinazolindions
US3726979A (en) * 1971-04-09 1973-04-10 E Hong Method of producing serotonin antagonism
US3819630A (en) * 1972-08-21 1974-06-25 R Parcell 3-(1-piperazinylalkyl)-2,4-quinazolinedione compounds and methods for their production
US3879393A (en) * 1973-06-18 1975-04-22 Miles Lab Derivatives of 1,3-disubstituted 2,4(1h,3h)-quinazolinediones
EP0040793B1 (en) * 1980-05-22 1985-08-28 Masayuki Ishikawa Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof

Also Published As

Publication number Publication date
JPS58159480A (ja) 1983-09-21
ATE27817T1 (de) 1987-07-15
US4578465A (en) 1986-03-25
MX7157E (es) 1987-11-27
DK120483A (da) 1983-09-18
ES527318A0 (es) 1985-05-01
KR840004104A (ko) 1984-10-06
DK120483D0 (da) 1983-03-15
DK156064C (da) 1989-11-06
KR900004125B1 (ko) 1990-06-16
DK156064B (da) 1989-06-19
JPH033669B2 (es) 1991-01-21
EP0089065B1 (en) 1987-06-16
ES520693A0 (es) 1984-05-01
DE3372095D1 (en) 1987-07-23
EP0089065A2 (en) 1983-09-21
ES8404347A1 (es) 1984-05-01
FI830893L (fi) 1983-09-18
ES8504777A1 (es) 1985-05-01
EP0089065A3 (en) 1984-05-23
FI77456B (fi) 1988-11-30
DE89065T1 (de) 1985-04-11
ES527319A0 (es) 1985-05-01
FI830893A0 (fi) 1983-03-17
CA1248102A (en) 1989-01-03
ES8504778A1 (es) 1985-05-01
FI77456C (fi) 1989-03-10

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