GB1536195A - 3-phenyl-sec-butylamine derivatives - Google Patents
3-phenyl-sec-butylamine derivativesInfo
- Publication number
- GB1536195A GB1536195A GB6837/76A GB683776A GB1536195A GB 1536195 A GB1536195 A GB 1536195A GB 6837/76 A GB6837/76 A GB 6837/76A GB 683776 A GB683776 A GB 683776A GB 1536195 A GB1536195 A GB 1536195A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- alkyl group
- sec
- phenyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010015535 Euphoric mood Diseases 0.000 abstract 1
- 229940025084 amphetamine Drugs 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002743 euphoric effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/49—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
3-Phenyl-sec-butylamine derivatives of the formula I <IMAGE> in which R<1> and R<2>, which are identical or different, are hydrogen, an alkyl group with 1 to 5 carbon atoms or a halogen atom, R<3> is an alkyl group with 1 to 5 carbon atoms or the benzyl group, R<4> is hydrogen, an alkyl group with 1 to 5 carbon atoms or the benzyl group, where R<1> and/or R<2> are an alkyl group with 1 to 5 carbon atoms or a halogen atom when R<3> and R<4> are the methyl group, are valuable antidepressants which have a lower euphoric or central stimulant effect than amphetamine; they are also valuable agents for eliminating anxiety states. They are prepared by reducing a compound of the formula II <IMAGE> in which A is -CH2-CH2- or -CH=CH-.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7501956A SE396748B (en) | 1975-02-21 | 1975-02-21 | PROCEDURE FOR PREPARATION OF 3-PHENYL-SEC -BUTYLAMINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1536195A true GB1536195A (en) | 1978-12-20 |
Family
ID=20323758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6837/76A Expired GB1536195A (en) | 1975-02-21 | 1976-02-20 | 3-phenyl-sec-butylamine derivatives |
Country Status (12)
| Country | Link |
|---|---|
| AT (1) | AT340384B (en) |
| AU (1) | AU499650B2 (en) |
| BE (1) | BE838739A (en) |
| CA (1) | CA1078408A (en) |
| CH (1) | CH609673A5 (en) |
| DE (1) | DE2606393A1 (en) |
| FR (1) | FR2301236A2 (en) |
| GB (1) | GB1536195A (en) |
| IE (1) | IE43129B1 (en) |
| LU (1) | LU74386A1 (en) |
| NL (1) | NL7601605A (en) |
| SE (1) | SE396748B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU701981B2 (en) | 1995-12-21 | 1999-02-11 | Sumitomo Chemical Company, Limited | Triazole derivatives and uses thereof |
-
1975
- 1975-02-21 SE SE7501956A patent/SE396748B/en unknown
-
1976
- 1976-02-06 AT AT82076A patent/AT340384B/en not_active IP Right Cessation
- 1976-02-12 CA CA245,616A patent/CA1078408A/en not_active Expired
- 1976-02-13 CH CH180076A patent/CH609673A5/en not_active IP Right Cessation
- 1976-02-17 NL NL7601605A patent/NL7601605A/en not_active Application Discontinuation
- 1976-02-18 DE DE19762606393 patent/DE2606393A1/en not_active Withdrawn
- 1976-02-19 AU AU11247/76A patent/AU499650B2/en not_active Expired
- 1976-02-20 LU LU74386A patent/LU74386A1/xx unknown
- 1976-02-20 BE BE164457A patent/BE838739A/en unknown
- 1976-02-20 IE IE341/76A patent/IE43129B1/en unknown
- 1976-02-20 GB GB6837/76A patent/GB1536195A/en not_active Expired
- 1976-02-20 FR FR7604707A patent/FR2301236A2/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IE43129B1 (en) | 1980-12-31 |
| AU1124776A (en) | 1977-08-25 |
| ATA82076A (en) | 1977-04-15 |
| AU499650B2 (en) | 1979-04-26 |
| SE396748B (en) | 1977-10-03 |
| BE838739A (en) | 1976-08-20 |
| IE43129L (en) | 1976-08-21 |
| LU74386A1 (en) | 1977-01-06 |
| CA1078408A (en) | 1980-05-27 |
| SE7501956L (en) | 1976-08-23 |
| CH609673A5 (en) | 1979-03-15 |
| NL7601605A (en) | 1976-08-24 |
| FR2301236A2 (en) | 1976-09-17 |
| FR2301236B2 (en) | 1980-07-04 |
| AT340384B (en) | 1977-12-12 |
| DE2606393A1 (en) | 1976-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |