PH30998A - Benzimidazolone derivatives. - Google Patents

Benzimidazolone derivatives.

Info

Publication number
PH30998A
PH30998A PH44739A PH44739A PH30998A PH 30998 A PH30998 A PH 30998A PH 44739 A PH44739 A PH 44739A PH 44739 A PH44739 A PH 44739A PH 30998 A PH30998 A PH 30998A
Authority
PH
Philippines
Prior art keywords
alkyl
substituted
mono
optionally
alkoxy
Prior art date
Application number
PH44739A
Other languages
English (en)
Inventor
Bietti Giuseppe
Giraldo Ettore
Bignotti Maura
Borsini Franco
Turconi Marco
Original Assignee
Boehringer Ingelheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Italia filed Critical Boehringer Ingelheim Italia
Publication of PH30998A publication Critical patent/PH30998A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH44739A 1991-07-30 1992-07-29 Benzimidazolone derivatives. PH30998A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912118A IT1251144B (it) 1991-07-30 1991-07-30 Derivati del benzimidazolone

Publications (1)

Publication Number Publication Date
PH30998A true PH30998A (en) 1997-12-23

Family

ID=11360463

Family Applications (1)

Application Number Title Priority Date Filing Date
PH44739A PH30998A (en) 1991-07-30 1992-07-29 Benzimidazolone derivatives.

Country Status (32)

Country Link
US (1) US5576318A (ru)
EP (1) EP0526434B1 (ru)
JP (1) JP2989667B2 (ru)
KR (1) KR100263495B1 (ru)
AT (1) ATE191910T1 (ru)
AU (1) AU665366B2 (ru)
CA (1) CA2114542C (ru)
CZ (1) CZ281511B6 (ru)
DE (1) DE69230926T2 (ru)
DK (1) DK0526434T3 (ru)
EE (1) EE03070B1 (ru)
ES (1) ES2144412T3 (ru)
FI (1) FI111460B (ru)
GR (1) GR3033947T3 (ru)
HK (1) HK1010725A1 (ru)
HU (2) HUT70195A (ru)
IE (1) IE922464A1 (ru)
IL (1) IL102665A (ru)
IT (1) IT1251144B (ru)
MX (1) MX9204139A (ru)
NO (1) NO304070B1 (ru)
NZ (1) NZ243777A (ru)
PH (1) PH30998A (ru)
PL (1) PL171329B1 (ru)
PT (1) PT526434E (ru)
RU (1) RU2096411C1 (ru)
SG (1) SG52407A1 (ru)
SK (1) SK279292B6 (ru)
TW (1) TW209862B (ru)
UA (1) UA42684C2 (ru)
WO (1) WO1993003016A1 (ru)
ZA (1) ZA925682B (ru)

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JP3004727B2 (ja) * 1994-08-05 2000-01-31 ファイザー・インコーポレーテッド ドパミン作動性活性を有するベンゾイミダゾール誘導体
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US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
UA78974C2 (en) * 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
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BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
JP6448541B2 (ja) * 2012-10-11 2019-01-09 サザン リサーチ インスティテュート アミノアルキルピペラジンの尿素及びアミド誘導体並びにその使用
CN104926734B (zh) * 2015-07-07 2017-04-05 苏州立新制药有限公司 氟班色林的制备方法
WO2017076213A1 (zh) * 2015-11-02 2017-05-11 苏州旺山旺水生物医药有限公司 苯并咪唑类化合物、其制备方法及用途
WO2017076356A1 (zh) * 2015-11-05 2017-05-11 苏州晶云药物科技有限公司 氟班色林的新晶型及其制备方法
CN106749038A (zh) * 2015-11-25 2017-05-31 山东诚创医药技术开发有限公司 一种氟班色林的制备方法
CN106866546A (zh) * 2015-12-10 2017-06-20 常州爱诺新睿医药技术有限公司 氟班色林或其药学上可接受的盐与药用辅料的固体分散体及其制备方法
CN108699007A (zh) 2016-01-31 2018-10-23 孟晓明 氟班色林的新晶型及其制备方法及其用途
CN108349908B (zh) * 2016-02-02 2021-07-20 深圳市塔吉瑞生物医药有限公司 一种取代的苯并咪唑酮化合物及包含该化合物的组合物
CN107235913B (zh) * 2016-03-29 2020-07-10 苏州科伦药物研究有限公司 工业规模高效制造优质氟班色林的方法
CN106866582A (zh) * 2017-01-10 2017-06-20 广州隽沐生物科技有限公司 一种氟班色林中间体的制备方法
HU231283B1 (hu) 2018-08-01 2022-09-28 Richter Gedeon Nyrt Eljárás a flibanserin többlépéses folyamatos áramú előállítására
CA3211341A1 (en) * 2021-03-19 2022-09-22 Centre National De La Recherche Scientifique Applications of biased ligands of the serotonin 5-ht7 receptor for the treatment of pain, multiple sclerosis and the control of thermoregulation

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Also Published As

Publication number Publication date
SK10194A3 (en) 1994-12-07
PL302163A1 (en) 1994-07-11
NO940306D0 (no) 1994-01-28
DE69230926T2 (de) 2000-10-05
FI940420A0 (fi) 1994-01-28
KR100263495B1 (ko) 2000-11-01
DK0526434T3 (da) 2000-07-17
SK279292B6 (sk) 1998-09-09
NO940306L (no) 1994-03-14
IL102665A (en) 1996-10-31
HUT70195A (en) 1995-09-28
EP0526434B1 (en) 2000-04-19
IE922464A1 (en) 1993-02-10
JP2989667B2 (ja) 1999-12-13
JPH06509575A (ja) 1994-10-27
PT526434E (pt) 2000-08-31
EE03070B1 (et) 1998-02-16
ZA925682B (en) 1994-01-31
AU665366B2 (en) 1996-01-04
HU9400255D0 (en) 1994-05-30
CA2114542C (en) 2004-02-24
NO304070B1 (no) 1998-10-19
HK1010725A1 (en) 1999-06-25
PL171329B1 (pl) 1997-04-30
CZ281511B6 (cs) 1996-10-16
NZ243777A (en) 1995-04-27
ITMI912118A1 (it) 1993-01-31
UA42684C2 (ru) 2001-11-15
EP0526434A1 (en) 1993-02-03
AU2427592A (en) 1993-03-02
GR3033947T3 (en) 2000-11-30
ES2144412T3 (es) 2000-06-16
ITMI912118A0 (it) 1991-07-30
RU2096411C1 (ru) 1997-11-20
IT1251144B (it) 1995-05-04
DE69230926D1 (de) 2000-05-25
CZ17094A3 (en) 1994-05-18
SG52407A1 (en) 1998-09-28
WO1993003016A1 (en) 1993-02-18
HU211256A9 (en) 1995-11-28
US5576318A (en) 1996-11-19
CA2114542A1 (en) 1993-02-18
FI111460B (fi) 2003-07-31
TW209862B (ru) 1993-07-21
FI940420A (fi) 1994-01-28
MX9204139A (es) 1993-01-01
ATE191910T1 (de) 2000-05-15

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