PH26419A - Infusion solutions of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxyic acid - Google Patents
Infusion solutions of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxyic acid Download PDFInfo
- Publication number
- PH26419A PH26419A PH34403A PH34403A PH26419A PH 26419 A PH26419 A PH 26419A PH 34403 A PH34403 A PH 34403A PH 34403 A PH34403 A PH 34403A PH 26419 A PH26419 A PH 26419A
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- Philippines
- Prior art keywords
- acid
- solution according
- infusion solution
- active compound
- mols
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853537761 DE3537761A1 (de) | 1985-10-24 | 1985-10-24 | Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH26419A true PH26419A (en) | 1992-07-15 |
Family
ID=6284294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH34403A PH26419A (en) | 1985-10-24 | 1986-10-23 | Infusion solutions of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinoline-3-carboxyic acid |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4957922A (xx) |
| EP (1) | EP0219784B1 (xx) |
| JP (1) | JPH0714879B2 (xx) |
| KR (1) | KR940002664B1 (xx) |
| AR (1) | AR244085A1 (xx) |
| AT (1) | ATE59003T1 (xx) |
| AU (1) | AU571796B2 (xx) |
| CA (1) | CA1282006C (xx) |
| CY (1) | CY1729A (xx) |
| DD (1) | DD252125A5 (xx) |
| DE (2) | DE3537761A1 (xx) |
| DK (1) | DK175494B1 (xx) |
| ES (1) | ES2021571B3 (xx) |
| FI (1) | FI84555C (xx) |
| GR (1) | GR3002544T3 (xx) |
| HK (1) | HK115593A (xx) |
| HU (1) | HUT42952A (xx) |
| IE (1) | IE59385B1 (xx) |
| IL (1) | IL80380A (xx) |
| NO (1) | NO864022L (xx) |
| NZ (1) | NZ218016A (xx) |
| PH (1) | PH26419A (xx) |
| PL (1) | PL152336B1 (xx) |
| PT (1) | PT83588B (xx) |
| SU (1) | SU1487801A3 (xx) |
| UA (1) | UA8033A1 (xx) |
| ZA (1) | ZA868057B (xx) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5281596A (en) * | 1986-02-19 | 1994-01-25 | Bayer Aktiengesellschaft | Antibacterial drugs for fish |
| JPS62192321A (ja) * | 1986-02-19 | 1987-08-22 | Bayer Japan Kk | 魚類用抗菌剤 |
| FI883337A (fi) * | 1987-07-16 | 1989-01-17 | Bristol Myers Co | Icke-vattenloesningar av doxorubicinhydroklorin. |
| FI883338A (fi) * | 1987-07-16 | 1989-01-17 | Bristol Myers Co | Vattenloesningar av doxorubicinhydroklorid. |
| JPH01175935A (ja) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | 凍結乾燥注射剤 |
| DE3902079A1 (de) * | 1988-04-15 | 1989-10-26 | Bayer Ag | I.m. injektionsformen von gyrase-inhibitoren |
| NZ232740A (en) * | 1989-04-20 | 1992-06-25 | Riker Laboratories Inc | Solution for parenteral administration comprising a 1h-imidazo(4,5-c) quinolin-4-amine derivative, an acid and a tonicity adjuster |
| FR2655545B1 (fr) * | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | Nouvelle application therapeutique des derives des fluoroquinolones. |
| US6300361B1 (en) * | 1990-07-25 | 2001-10-09 | Novartis Ag | Stabilized pharmaceutical compositions comprising acid donors |
| FR2681863B1 (fr) * | 1991-09-27 | 1995-02-03 | Rhone Dpc Europ | Solution de sparfloxacine sa preparation et sel la constituant. |
| KR0159540B1 (ko) * | 1992-01-21 | 1998-12-01 | 김정순 | 퀴놀론-카복실산의 염 및 그 함유조성물 |
| US5290794A (en) * | 1992-10-27 | 1994-03-01 | Warner Lambert Co. | Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms |
| ES2088742B1 (es) | 1994-06-29 | 1997-03-16 | Salvat Lab Sa | Composicion antibiotica de aplicacion otica. |
| DE19500784A1 (de) * | 1995-01-13 | 1996-07-18 | Bayer Ag | Enrofloxacin-Injektions- oder Infusionslösungen |
| JPH08213881A (ja) * | 1995-02-02 | 1996-08-20 | Fujitsu Ltd | 周波数制御回路 |
| US5800833A (en) * | 1995-02-27 | 1998-09-01 | University Of British Columbia | Method for loading lipid vesicles |
| PT782448E (pt) * | 1995-06-06 | 2002-07-31 | Bayer Ag | Formulacoes oticas antibacterianas nao ototoxicas nao sensibilizantes nao irritantes |
| US5843930A (en) * | 1995-06-06 | 1998-12-01 | Bayer Corporation | Method of treating otitis with ciprofloxacin-hydrocortisone suspension |
| IT1280428B1 (it) * | 1995-07-14 | 1998-01-20 | R R A S R L | Composizione farmaceutica per uso topico |
| ES2106680B1 (es) * | 1995-08-03 | 1998-07-01 | Vita Invest Sa | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes. |
| DE19730023A1 (de) * | 1997-07-11 | 1999-01-14 | Bayer Ag | Hochreine Ciprofloxacin-Infusion |
| ATE555780T1 (de) * | 1997-10-24 | 2012-05-15 | John P Blass | Nahrungsergänzungsmittel für metabolische hirnleistungsstörungen |
| US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| DE19937116A1 (de) | 1999-08-06 | 2001-02-08 | Bayer Ag | Moxifloxacin Kochsalzformulierung |
| DE10018783A1 (de) * | 2000-04-15 | 2001-10-25 | Fresenius Kabi De Gmbh | Lagerstabile Infusionslösung des Ciprofloxacins mit verringertem Säuregehalt |
| CA2406849C (en) * | 2000-04-24 | 2007-10-23 | Daiichi Pharmaceutical Co., Ltd. | Stabilized liquid preparation |
| DE10048510A1 (de) * | 2000-09-29 | 2002-05-16 | Fresenius Kabi De Gmbh | Lagerstabile Infusionslösung des Ciprofloxacins mit verringertem Säuregehalt |
| JP2006151808A (ja) * | 2002-12-24 | 2006-06-15 | Dai Ichi Seiyaku Co Ltd | 抗菌性水性製剤 |
| US6861422B2 (en) * | 2003-02-26 | 2005-03-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions |
| DE102004005186B3 (de) * | 2004-02-02 | 2005-10-13 | Krka Tovarna Zdravil, D.D. | Verfahren zur Herstellung von gereinigtem Ciprofloxacin |
| WO2005123137A2 (en) * | 2004-06-18 | 2005-12-29 | Ranbaxy Laboratories Limited | Lyophilized pharmaceutical composition comprising moxifloxacin hydrochloride |
| DE102004029784A1 (de) * | 2004-06-21 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004033670A1 (de) * | 2004-07-09 | 2006-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel |
| US20060035903A1 (en) * | 2004-08-14 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Storage stable perfusion solution for dihydropteridinones |
| US7728134B2 (en) * | 2004-08-14 | 2010-06-01 | Boehringer Ingelheim International Gmbh | Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| US20060058311A1 (en) | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
| US7759485B2 (en) * | 2004-08-14 | 2010-07-20 | Boehringer Ingelheim International Gmbh | Process for the manufacture of dihydropteridinones |
| US20060074088A1 (en) * | 2004-08-14 | 2006-04-06 | Boehringer Ingelheim International Gmbh | Dihydropteridinones for the treatment of cancer diseases |
| EP1632493A1 (de) * | 2004-08-25 | 2006-03-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| EP1630163A1 (de) * | 2004-08-25 | 2006-03-01 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004054873A1 (de) | 2004-11-12 | 2006-05-18 | Bayer Healthcare Ag | Behandlung von Mastitis |
| DE102004058337A1 (de) * | 2004-12-02 | 2006-06-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten |
| EP1827498A2 (de) * | 2004-12-09 | 2007-09-05 | Bayer HealthCare AG | Stabilisierung von glucocorticoidestern mit säuren |
| DE102005055385A1 (de) * | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
| FR2896416B1 (fr) * | 2006-01-24 | 2010-08-13 | Vetoquinol | Composition anti-infectieuse comprenant un compose de type pyrido (3,2,1-ij)-benzoxadiazine |
| US7439358B2 (en) * | 2006-02-08 | 2008-10-21 | Boehringer Ingelheim International Gmbh | Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
| US20070197548A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
| TW200900066A (en) * | 2007-03-22 | 2009-01-01 | Daiichi Sankyo Co Ltd | Quinolone medical composition containing alcohols |
| BRPI0810192C1 (pt) * | 2007-04-13 | 2021-05-25 | Dong Wha Pharm Co Ltd | aspartato do ácido 1-ciclopropil-6-fluoro-7-(8-metoxiimino-2,6-diaza-espiro [3,4] oct-6-il)-4-oxo-1,4-diidro- [1,8] naftiridina-3-carboxílico, método para preparação do mesmo e composição farmacêutica antimicrobiana compreendendo o mesmo. |
| JP5217276B2 (ja) * | 2007-07-19 | 2013-06-19 | ニプロ株式会社 | 注射用抗菌剤の製造方法 |
| JP5261487B2 (ja) * | 2007-08-03 | 2013-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ジヒドロプテリジノン誘導体の結晶形 |
| WO2010146478A1 (en) * | 2009-05-08 | 2010-12-23 | Ranbaxy Laboratories Limited | Parenteral composition comprising a fluoroquinolone compound and a nitroimidazole compound |
| US8546566B2 (en) | 2010-10-12 | 2013-10-01 | Boehringer Ingelheim International Gmbh | Process for manufacturing dihydropteridinones and intermediates thereof |
| US9358233B2 (en) | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
| US9370535B2 (en) | 2011-05-17 | 2016-06-21 | Boehringer Ingelheim International Gmbh | Method for treatment of advanced solid tumors |
| JP2016525532A (ja) | 2013-07-26 | 2016-08-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 骨髄異形成症候群の処置 |
| KR101646324B1 (ko) * | 2014-03-04 | 2016-08-05 | 동화약품주식회사 | 1-시클로프로필-6-플루오로-7-(8-메톡시이미노-2,6-디아자-스피로[3,4]옥트-6-일)-4-옥소-1,4-디히드로-[1,8]나프티리딘-3-카르복실산 디-아스파르트산염의 수화물 및 이를 포함하는 항균활성 조성물 |
| US9867831B2 (en) | 2014-10-01 | 2018-01-16 | Boehringer Ingelheim International Gmbh | Combination treatment of acute myeloid leukemia and myelodysplastic syndrome |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS497419A (xx) * | 1972-05-24 | 1974-01-23 | ||
| JPS57188515A (en) * | 1981-05-13 | 1982-11-19 | Kyoto Yakuhin Kogyo Kk | Stabilized aqueous dopamine preparation |
| HU188181B (en) * | 1981-06-11 | 1986-03-28 | Warner-Lambert Co,Us | Process for producing salts of naphtiridine and quinoline compounds of antimicrobial activity |
| DE3306771A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3333719A1 (de) * | 1983-09-17 | 1985-04-04 | Bayer Ag | Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren |
-
1985
- 1985-10-24 DE DE19853537761 patent/DE3537761A1/de not_active Withdrawn
-
1986
- 1986-10-09 NO NO864022A patent/NO864022L/no unknown
- 1986-10-13 ES ES86114131T patent/ES2021571B3/es not_active Expired - Lifetime
- 1986-10-13 AT AT86114131T patent/ATE59003T1/de not_active IP Right Cessation
- 1986-10-13 EP EP86114131A patent/EP0219784B1/de not_active Expired - Lifetime
- 1986-10-13 DE DE8686114131T patent/DE3676158D1/de not_active Expired - Lifetime
- 1986-10-21 SU SU86A patent/SU1487801A3/ru active
- 1986-10-21 IL IL80380A patent/IL80380A/xx not_active IP Right Cessation
- 1986-10-21 NZ NZ218016A patent/NZ218016A/xx unknown
- 1986-10-21 UA UA4028324A patent/UA8033A1/uk unknown
- 1986-10-21 AR AR86305638A patent/AR244085A1/es active
- 1986-10-21 PT PT83588A patent/PT83588B/pt unknown
- 1986-10-22 FI FI864272A patent/FI84555C/fi not_active IP Right Cessation
- 1986-10-22 CA CA000521092A patent/CA1282006C/en not_active Expired - Lifetime
- 1986-10-22 DD DD86295467A patent/DD252125A5/de not_active IP Right Cessation
- 1986-10-23 ZA ZA868057A patent/ZA868057B/xx unknown
- 1986-10-23 KR KR1019860008863A patent/KR940002664B1/ko not_active IP Right Cessation
- 1986-10-23 IE IE280386A patent/IE59385B1/en not_active IP Right Cessation
- 1986-10-23 PH PH34403A patent/PH26419A/en unknown
- 1986-10-23 AU AU64327/86A patent/AU571796B2/en not_active Expired
- 1986-10-23 DK DK198605078A patent/DK175494B1/da not_active IP Right Cessation
- 1986-10-23 PL PL1986262006A patent/PL152336B1/pl unknown
- 1986-10-23 JP JP61250909A patent/JPH0714879B2/ja not_active Expired - Fee Related
- 1986-10-24 HU HU864477A patent/HUT42952A/hu unknown
-
1989
- 1989-03-29 US US07/329,922 patent/US4957922A/en not_active Expired - Lifetime
-
1990
- 1990-12-13 GR GR90400940T patent/GR3002544T3/el unknown
-
1993
- 1993-10-28 HK HK1155/93A patent/HK115593A/xx not_active IP Right Cessation
-
1994
- 1994-05-06 CY CY172994A patent/CY1729A/xx unknown
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