DK507886A - Infusionsoploesninger af 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinolin-3-carboxylsyre, lyofilisater og koncentrater og fremgangsmaade til deres fremstilling samt deres anvendelse - Google Patents

Infusionsoploesninger af 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-quinolin-3-carboxylsyre, lyofilisater og koncentrater og fremgangsmaade til deres fremstilling samt deres anvendelse

Info

Publication number
DK507886A
DK507886A DK507886A DK507886A DK507886A DK 507886 A DK507886 A DK 507886A DK 507886 A DK507886 A DK 507886A DK 507886 A DK507886 A DK 507886A DK 507886 A DK507886 A DK 507886A
Authority
DK
Denmark
Prior art keywords
lyophilizates
piperazinyl
quinoline
cyclopropyl
dihydro
Prior art date
Application number
DK507886A
Other languages
English (en)
Other versions
DK507886D0 (da
DK175494B1 (da
Inventor
Robert Frank Lammens
Hans Friedrich Mahler
Peter Serno
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6284294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK507886(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK507886D0 publication Critical patent/DK507886D0/da
Publication of DK507886A publication Critical patent/DK507886A/da
Application granted granted Critical
Publication of DK175494B1 publication Critical patent/DK175494B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK198605078A 1985-10-24 1986-10-23 Infusionsoplösninger af 1-cyclopropyl-6-fluor-1,4-dihydroxy-4-oxo-7-(1-piperazinyl)-quinolin-3-carboxylsyre, lyofilisater deraf og fremgangsmåde til deres fremstilling samt deres anvendelse DK175494B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3537761 1985-10-24
DE19853537761 DE3537761A1 (de) 1985-10-24 1985-10-24 Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure

Publications (3)

Publication Number Publication Date
DK507886D0 DK507886D0 (da) 1986-10-23
DK507886A true DK507886A (da) 1987-04-25
DK175494B1 DK175494B1 (da) 2004-11-08

Family

ID=6284294

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198605078A DK175494B1 (da) 1985-10-24 1986-10-23 Infusionsoplösninger af 1-cyclopropyl-6-fluor-1,4-dihydroxy-4-oxo-7-(1-piperazinyl)-quinolin-3-carboxylsyre, lyofilisater deraf og fremgangsmåde til deres fremstilling samt deres anvendelse

Country Status (27)

Country Link
US (1) US4957922A (da)
EP (1) EP0219784B1 (da)
JP (1) JPH0714879B2 (da)
KR (1) KR940002664B1 (da)
AR (1) AR244085A1 (da)
AT (1) ATE59003T1 (da)
AU (1) AU571796B2 (da)
CA (1) CA1282006C (da)
CY (1) CY1729A (da)
DD (1) DD252125A5 (da)
DE (2) DE3537761A1 (da)
DK (1) DK175494B1 (da)
ES (1) ES2021571B3 (da)
FI (1) FI84555C (da)
GR (1) GR3002544T3 (da)
HK (1) HK115593A (da)
HU (1) HUT42952A (da)
IE (1) IE59385B1 (da)
IL (1) IL80380A (da)
NO (1) NO864022L (da)
NZ (1) NZ218016A (da)
PH (1) PH26419A (da)
PL (1) PL152336B1 (da)
PT (1) PT83588B (da)
SU (1) SU1487801A3 (da)
UA (1) UA8033A1 (da)
ZA (1) ZA868057B (da)

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JP2006151808A (ja) * 2002-12-24 2006-06-15 Dai Ichi Seiyaku Co Ltd 抗菌性水性製剤
US6861422B2 (en) * 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
DE102004005186B3 (de) * 2004-02-02 2005-10-13 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von gereinigtem Ciprofloxacin
WO2005123137A2 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Lyophilized pharmaceutical composition comprising moxifloxacin hydrochloride
DE102004029784A1 (de) * 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) * 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US20060035903A1 (en) * 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US7728134B2 (en) * 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
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US20060074088A1 (en) * 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
EP1632493A1 (de) * 2004-08-25 2006-03-08 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1630163A1 (de) * 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004054873A1 (de) 2004-11-12 2006-05-18 Bayer Healthcare Ag Behandlung von Mastitis
DE102004058337A1 (de) * 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
EP1827498A2 (de) * 2004-12-09 2007-09-05 Bayer HealthCare AG Stabilisierung von glucocorticoidestern mit säuren
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
FR2896416B1 (fr) * 2006-01-24 2010-08-13 Vetoquinol Composition anti-infectieuse comprenant un compose de type pyrido (3,2,1-ij)-benzoxadiazine
US7439358B2 (en) * 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
US20070197548A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
TW200900066A (en) * 2007-03-22 2009-01-01 Daiichi Sankyo Co Ltd Quinolone medical composition containing alcohols
BRPI0810192C1 (pt) * 2007-04-13 2021-05-25 Dong Wha Pharm Co Ltd aspartato do ácido 1-ciclopropil-6-fluoro-7-(8-metoxiimino-2,6-diaza-espiro [3,4] oct-6-il)-4-oxo-1,4-diidro- [1,8] naftiridina-3-carboxílico, método para preparação do mesmo e composição farmacêutica antimicrobiana compreendendo o mesmo.
JP5217276B2 (ja) * 2007-07-19 2013-06-19 ニプロ株式会社 注射用抗菌剤の製造方法
JP5261487B2 (ja) * 2007-08-03 2013-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ジヒドロプテリジノン誘導体の結晶形
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US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
JP2016525532A (ja) 2013-07-26 2016-08-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 骨髄異形成症候群の処置
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Also Published As

Publication number Publication date
FI864272A (fi) 1987-04-25
PH26419A (en) 1992-07-15
PT83588A (en) 1986-11-01
AU571796B2 (en) 1988-04-21
CA1282006C (en) 1991-03-26
HUT42952A (en) 1987-09-28
AR244085A1 (es) 1993-10-29
PT83588B (pt) 1989-05-31
DE3676158D1 (de) 1991-01-24
CY1729A (en) 1994-05-06
NZ218016A (en) 1989-02-24
DE3537761A1 (de) 1987-04-30
IL80380A0 (en) 1987-01-30
JPH0714879B2 (ja) 1995-02-22
JPS6299326A (ja) 1987-05-08
UA8033A1 (uk) 1995-12-26
KR940002664B1 (ko) 1994-03-28
ATE59003T1 (de) 1990-12-15
EP0219784A2 (de) 1987-04-29
HK115593A (en) 1993-11-05
ZA868057B (en) 1987-06-24
EP0219784B1 (de) 1990-12-12
EP0219784A3 (en) 1987-11-04
NO864022D0 (no) 1986-10-09
ES2021571B3 (es) 1991-11-16
NO864022L (no) 1987-04-27
GR3002544T3 (en) 1993-01-25
PL262006A1 (en) 1988-10-13
FI84555B (fi) 1991-09-13
FI84555C (fi) 1991-12-27
DK507886D0 (da) 1986-10-23
FI864272A0 (fi) 1986-10-22
KR870003786A (ko) 1987-05-04
SU1487801A3 (ru) 1989-06-15
IE862803L (en) 1987-04-24
DD252125A5 (de) 1987-12-09
IL80380A (en) 1990-11-29
PL152336B1 (en) 1990-12-31
DK175494B1 (da) 2004-11-08
IE59385B1 (en) 1994-02-23
AU6432786A (en) 1987-04-30
US4957922A (en) 1990-09-18

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