PH16946A - Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and pharmaceutical compositions containing the same - Google Patents

Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and pharmaceutical compositions containing the same

Info

Publication number
PH16946A
PH16946A PH20693A PH20693A PH16946A PH 16946 A PH16946 A PH 16946A PH 20693 A PH20693 A PH 20693A PH 20693 A PH20693 A PH 20693A PH 16946 A PH16946 A PH 16946A
Authority
PH
Philippines
Prior art keywords
heteromonocyclic
acylamido
cephem
unsaturated
carboxylic acid
Prior art date
Application number
PH20693A
Other languages
English (en)
Inventor
Nannini Giuliano
Perrone Ettore
Meinardi Giuseppe
Monti Gisella
Bianchi Alberta
Forgiona Angelo
Confalonieri Carlo
Severino Dino
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of PH16946A publication Critical patent/PH16946A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH20693A 1977-02-11 1978-01-20 Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and pharmaceutical compositions containing the same PH16946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20173/77A IT1075277B (it) 1977-02-11 1977-02-11 Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
PH16946A true PH16946A (en) 1984-04-24

Family

ID=11164407

Family Applications (1)

Application Number Title Priority Date Filing Date
PH20693A PH16946A (en) 1977-02-11 1978-01-20 Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and pharmaceutical compositions containing the same

Country Status (29)

Country Link
US (3) US4154830A (it)
JP (2) JPS5398991A (it)
AT (2) AT355206B (it)
AU (2) AU512934B2 (it)
BE (2) BE858433A (it)
CA (2) CA1103237A (it)
CH (3) CH632513A5 (it)
CS (3) CS196381B2 (it)
CY (1) CY1234A (it)
DE (2) DE2736471A1 (it)
DK (2) DK155944C (it)
FI (2) FI65259C (it)
FR (3) FR2380285A1 (it)
GB (4) GB1582295A (it)
GR (2) GR71901B (it)
HK (1) HK55284A (it)
HU (2) HU177596B (it)
IL (3) IL52708A0 (it)
IT (1) IT1075277B (it)
MY (1) MY8500446A (it)
NL (2) NL7708943A (it)
NO (4) NO152654C (it)
NZ (2) NZ184889A (it)
PH (1) PH16946A (it)
SE (4) SE7709002L (it)
SG (1) SG9484G (it)
SU (4) SU845788A3 (it)
YU (1) YU40307B (it)
ZA (2) ZA774835B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
JPS5593413A (en) * 1979-01-11 1980-07-15 Osaka Gas Co Ltd Lining method for inner surface of pipe
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4405617A (en) * 1980-02-11 1983-09-20 Fujisawa Pharmaceutical Co., Ltd. 3-(Propynyltetrazol)thiomethyl-3-cephems
GB2076803B (en) * 1980-05-16 1984-02-08 Erba Farmitalia Substituted 7-(a-oxy-imino-acetamido)-cephalosporins and process for their preparation
GB2186875A (en) * 1983-10-31 1987-08-26 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
ATE103923T1 (de) * 1985-12-13 1994-04-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
JPH0544294Y2 (it) * 1986-06-10 1993-11-10
AU7226591A (en) * 1990-01-12 1991-08-21 Dow Chemical Company, The Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5198445A (en) * 1990-01-12 1993-03-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials
US5126349A (en) * 1990-01-12 1992-06-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5157051A (en) * 1992-03-05 1992-10-20 The Dow Chemical Company Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents
US5155119A (en) * 1992-03-05 1992-10-13 The Dow Chemical Company 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials
US5206227A (en) * 1992-06-02 1993-04-27 The Dow Chemical Company Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials
JP3115455B2 (ja) * 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
SE9802974D0 (sv) 1998-09-03 1998-09-03 Astra Ab New crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
US3883520A (en) * 1973-08-17 1975-05-13 Smithkline Corp Substituted mercaptoacetamidocephalosporins
AU1303576A (en) * 1975-04-21 1977-10-20 Erba Carlo Spa Cephalosporins
ZA767084B (en) * 1975-12-16 1977-10-26 Erba Carlo Spa Thiadiazolyl derivatives of 7-acylamido 3-cephem-4-carboxylic acid and process for their preparation
US4057631A (en) * 1976-09-02 1977-11-08 Smithkline Corporation 7-(α-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-cephem-4-carboxylic acids
US4079134A (en) * 1976-09-24 1978-03-14 Smithkline Corporation 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
SE7800292L (sv) 1978-08-12
CY1234A (en) 1984-06-29
CS196381B2 (en) 1980-03-31
AU2786577A (en) 1979-02-15
DK155944B (da) 1989-06-05
AT355206B (de) 1980-02-25
BE858433A (fr) 1978-01-02
FI65259C (fi) 1984-04-10
CH632513A5 (de) 1982-10-15
IL53830A0 (en) 1978-04-30
CH636359A5 (de) 1983-05-31
FR2380285B1 (it) 1981-10-23
GB1590610A (en) 1981-06-03
US4172892A (en) 1979-10-30
CA1108603A (en) 1981-09-08
AT356270B (de) 1980-04-25
IT1075277B (it) 1985-04-22
SE7709002L (sv) 1978-08-12
HK55284A (en) 1984-07-27
DK11578A (da) 1978-08-12
DK353577A (da) 1978-08-12
CS199713B2 (en) 1980-07-31
CH634330A5 (de) 1983-01-31
US4388314A (en) 1983-06-14
YU40307B (en) 1985-12-31
NO152654B (no) 1985-07-22
YU210977A (en) 1982-10-31
IL52708A0 (en) 1977-10-31
JPS5398991A (en) 1978-08-29
FR2445834B1 (it) 1983-10-21
ATA585677A (de) 1979-07-15
FI65259B (fi) 1983-12-30
AU513444B2 (en) 1980-12-04
JPS53121788A (en) 1978-10-24
MY8500446A (en) 1985-12-31
DE2801644A1 (de) 1978-08-17
NO800239L (no) 1978-08-14
DE2736471C2 (it) 1988-09-22
NO794101L (no) 1978-08-14
NO780074L (no) 1978-08-14
SU845788A3 (ru) 1981-07-07
CS199714B2 (en) 1980-07-31
DE2736471A1 (de) 1978-08-17
SG9484G (en) 1984-08-03
SE8000110L (sv) 1980-01-08
JPS6153359B2 (it) 1986-11-17
NO152654C (no) 1985-10-30
HU177596B (en) 1981-11-28
GB1597261A (en) 1981-09-03
GR72589B (it) 1983-11-18
SE446536B (sv) 1986-09-22
NO772779L (no) 1978-08-14
FR2384783A1 (fr) 1978-10-20
US4154830A (en) 1979-05-15
AU3247678A (en) 1979-07-26
FR2384783B1 (it) 1982-12-03
FR2380285A1 (fr) 1978-09-08
GB1597262A (en) 1981-09-03
ATA32778A (de) 1979-09-15
FI780437A (fi) 1978-08-12
HU178918B (en) 1982-07-28
FR2445834A1 (fr) 1980-08-01
NZ184889A (en) 1979-07-11
SU856388A3 (ru) 1981-08-15
GB1582295A (en) 1981-01-07
SE8002904L (sv) 1980-04-18
DK155944C (da) 1989-12-04
FI772411A (fi) 1978-08-12
ZA774835B (en) 1978-07-26
SU904524A3 (ru) 1982-02-07
AU512934B2 (en) 1980-11-06
IL59527A0 (en) 1980-06-30
IL53830A (en) 1982-07-30
NL7800443A (nl) 1978-08-15
NL7708943A (nl) 1978-08-15
ZA78181B (en) 1979-08-29
NZ186236A (en) 1980-05-08
CA1103237A (en) 1981-06-16
GR71901B (it) 1983-08-11
BE863625A (fr) 1978-08-03
SU753361A3 (ru) 1980-07-30

Similar Documents

Publication Publication Date Title
NZ189574A (en) Dehydrocyclicimino acid derivatives pharmaceutical compositions
PH16946A (en) Heteromonocyclic and heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and pharmaceutical compositions containing the same
NZ187849A (en) Prostaglandin i derivatives and pharmaceutical compositions
IL56407A (en) 4-amino-3-sulfamoylpyridyl derivatives and pharmaceutical compositions containing them
NZ189296A (en) N-substituted-omega-aminoalkanoyl-omega-aminoalkanoic acids and pharmaceutical compositions
IL56078A (en) 9-hydrazono-6,7,8,9-tetrahydro-4h-pyrido(1,2-a)-pyrimidin-4-one derivatives,their preparation and pharmaceutical compositions containing them
DE2960972D1 (en) Derivative nonatetraenoic acid and pharmaceutical compositions
IL50507A0 (en) Phenoxyalkylcarboxylic acid derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
IL57268A0 (en) Di-o-n-alkyl clycerol derivatives and pharmaceutical compositions containing them
NZ190810A (en) 1-aminoalkyl-3-phenoxy-propan-2-ol derivatives pharmaceutical compositions
NZ187618A (en) Pharmaceutical compositions containing 4-hydroxy-2-oxo-1,2-dihydroquinolin-3-ylcarboxylic acids and certain of these acids
NZ184408A (en) 16-s-acyl derivatives of 16-deacetoxy-fusidic acid and pharmaceutical compositions
IL57939A0 (en) Pharmaceutical compositions containing n-substituted aziridine-2-carboxylic acid derivatives and processes for the preparation of said n-substituted aziridine-2-carboxylic acid derivatives
NZ188101A (en) N-substituted-2-aminobenzoic acid derivatives and pharmaceutical compositions
IL58621A0 (en) Pharmaceutical compositions comprising aryltrifluoroethanol derivatives
NZ187285A (en) Azacyclic derivatives of 6-amino-penam compounds and pharmaceutical compositions
NZ186059A (en) 3-sulphamoyl-5-pyrrolylal-kylbenzoic acid derivatives and pharmaceutical compositions
GB2010261B (en) Phenoxyalkanolamine derivatives the preparation thereof and pharmaceutical compositions containing them
IL61826A0 (en) Pharmaceutical compositions containing pyranoquinolinone derivatives
NZ189295A (en) N-substituted-acyl-aminoalkanoic acids and pharmaceutical compositions
PH14995A (en) Oxaminic acids and esters thereof and pharmaceutical compositions containing these compounds
NZ190665A (en) S-benzylcysteine derivatives and pharmaceutical compositions
NZ190007A (en) Steroid-spiro-oxazolidinone derivatives and pharmaceutical compositions
GB1544895A (en) 17-spirosultine derivatives and the corresponding ypsilon-hydroxy acids of estr-3-ones processes for preparing them and pharmaceutical compositions containing them
NZ190958A (en) 2-phenylamino-2-imidazoline derivatives pharmaceutical compositions