NL7708943A - Werkwijze ter bereiding van onverzadigde derivaten van 7-acylamido-3-cefem-4-carbonzuur. - Google Patents

Werkwijze ter bereiding van onverzadigde derivaten van 7-acylamido-3-cefem-4-carbonzuur.

Info

Publication number
NL7708943A
NL7708943A NL7708943A NL7708943A NL7708943A NL 7708943 A NL7708943 A NL 7708943A NL 7708943 A NL7708943 A NL 7708943A NL 7708943 A NL7708943 A NL 7708943A NL 7708943 A NL7708943 A NL 7708943A
Authority
NL
Netherlands
Prior art keywords
cefem
acylamido
carbonic acid
unsaturated derivatives
preparing unsaturated
Prior art date
Application number
NL7708943A
Other languages
English (en)
Dutch (nl)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of NL7708943A publication Critical patent/NL7708943A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7708943A 1977-02-11 1977-08-12 Werkwijze ter bereiding van onverzadigde derivaten van 7-acylamido-3-cefem-4-carbonzuur. NL7708943A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20173/77A IT1075277B (it) 1977-02-11 1977-02-11 Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
NL7708943A true NL7708943A (nl) 1978-08-15

Family

ID=11164407

Family Applications (2)

Application Number Title Priority Date Filing Date
NL7708943A NL7708943A (nl) 1977-02-11 1977-08-12 Werkwijze ter bereiding van onverzadigde derivaten van 7-acylamido-3-cefem-4-carbonzuur.
NL7800443A NL7800443A (nl) 1977-02-11 1978-01-13 Heteromonocyclische en heterobicyclische deri- vaten van onverzadigd 7-acylamido-3-cefem-4- -carbonzuur en werkwijze ter bereiding ervan.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL7800443A NL7800443A (nl) 1977-02-11 1978-01-13 Heteromonocyclische en heterobicyclische deri- vaten van onverzadigd 7-acylamido-3-cefem-4- -carbonzuur en werkwijze ter bereiding ervan.

Country Status (29)

Country Link
US (3) US4154830A (xx)
JP (2) JPS5398991A (xx)
AT (2) AT355206B (xx)
AU (2) AU512934B2 (xx)
BE (2) BE858433A (xx)
CA (2) CA1103237A (xx)
CH (3) CH632513A5 (xx)
CS (3) CS196381B2 (xx)
CY (1) CY1234A (xx)
DE (2) DE2736471A1 (xx)
DK (2) DK155944C (xx)
FI (2) FI65259C (xx)
FR (3) FR2380285A1 (xx)
GB (4) GB1582295A (xx)
GR (2) GR71901B (xx)
HK (1) HK55284A (xx)
HU (2) HU177596B (xx)
IL (3) IL52708A0 (xx)
IT (1) IT1075277B (xx)
MY (1) MY8500446A (xx)
NL (2) NL7708943A (xx)
NO (4) NO152654C (xx)
NZ (2) NZ184889A (xx)
PH (1) PH16946A (xx)
SE (4) SE7709002L (xx)
SG (1) SG9484G (xx)
SU (4) SU845788A3 (xx)
YU (1) YU40307B (xx)
ZA (2) ZA774835B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
JPS5593413A (en) * 1979-01-11 1980-07-15 Osaka Gas Co Ltd Lining method for inner surface of pipe
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4405617A (en) * 1980-02-11 1983-09-20 Fujisawa Pharmaceutical Co., Ltd. 3-(Propynyltetrazol)thiomethyl-3-cephems
GB2076803B (en) * 1980-05-16 1984-02-08 Erba Farmitalia Substituted 7-(a-oxy-imino-acetamido)-cephalosporins and process for their preparation
GB2186875A (en) * 1983-10-31 1987-08-26 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
DE3689762T2 (de) * 1985-12-13 1994-08-18 Takeda Chemical Industries Ltd Antibakterielle Verbindungen, ihre Herstellung und Verwendung.
JPH0544294Y2 (xx) * 1986-06-10 1993-11-10
EP0594583A1 (en) * 1990-01-12 1994-05-04 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5126349A (en) * 1990-01-12 1992-06-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5198445A (en) * 1990-01-12 1993-03-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials
US5157051A (en) * 1992-03-05 1992-10-20 The Dow Chemical Company Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents
US5155119A (en) * 1992-03-05 1992-10-13 The Dow Chemical Company 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials
US5206227A (en) * 1992-06-02 1993-04-27 The Dow Chemical Company Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials
JP3115455B2 (ja) * 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
SE9802974D0 (sv) * 1998-09-03 1998-09-03 Astra Ab New crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
US3883520A (en) * 1973-08-17 1975-05-13 Smithkline Corp Substituted mercaptoacetamidocephalosporins
AU1303576A (en) * 1975-04-21 1977-10-20 Erba Carlo Spa Cephalosporins
ZA767084B (en) * 1975-12-16 1977-10-26 Erba Carlo Spa Thiadiazolyl derivatives of 7-acylamido 3-cephem-4-carboxylic acid and process for their preparation
US4057631A (en) * 1976-09-02 1977-11-08 Smithkline Corporation 7-(α-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-cephem-4-carboxylic acids
US4079134A (en) * 1976-09-24 1978-03-14 Smithkline Corporation 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
GR71901B (xx) 1983-08-11
AU512934B2 (en) 1980-11-06
FI780437A (fi) 1978-08-12
PH16946A (en) 1984-04-24
CA1108603A (en) 1981-09-08
CA1103237A (en) 1981-06-16
DE2801644A1 (de) 1978-08-17
JPS5398991A (en) 1978-08-29
FR2384783B1 (xx) 1982-12-03
SU753361A3 (ru) 1980-07-30
SE8002904L (sv) 1980-04-18
CY1234A (en) 1984-06-29
YU40307B (en) 1985-12-31
HU177596B (en) 1981-11-28
DK155944B (da) 1989-06-05
FI65259C (fi) 1984-04-10
FI65259B (fi) 1983-12-30
SU904524A3 (ru) 1982-02-07
US4388314A (en) 1983-06-14
SE7709002L (sv) 1978-08-12
AU3247678A (en) 1979-07-26
JPS53121788A (en) 1978-10-24
DE2736471A1 (de) 1978-08-17
IT1075277B (it) 1985-04-22
HK55284A (en) 1984-07-27
NZ184889A (en) 1979-07-11
HU178918B (en) 1982-07-28
NO780074L (no) 1978-08-14
AU513444B2 (en) 1980-12-04
US4154830A (en) 1979-05-15
GB1597262A (en) 1981-09-03
IL52708A0 (en) 1977-10-31
CH632513A5 (de) 1982-10-15
ZA78181B (en) 1979-08-29
BE863625A (fr) 1978-08-03
NO152654B (no) 1985-07-22
FR2445834B1 (xx) 1983-10-21
CS196381B2 (en) 1980-03-31
CH634330A5 (de) 1983-01-31
DK11578A (da) 1978-08-12
SE7800292L (sv) 1978-08-12
ATA585677A (de) 1979-07-15
US4172892A (en) 1979-10-30
SU845788A3 (ru) 1981-07-07
NZ186236A (en) 1980-05-08
NL7800443A (nl) 1978-08-15
GB1582295A (en) 1981-01-07
JPS6153359B2 (xx) 1986-11-17
CS199713B2 (en) 1980-07-31
GR72589B (xx) 1983-11-18
FI772411A (fi) 1978-08-12
GB1590610A (en) 1981-06-03
NO794101L (no) 1978-08-14
NO152654C (no) 1985-10-30
GB1597261A (en) 1981-09-03
SE8000110L (sv) 1980-01-08
IL53830A0 (en) 1978-04-30
ZA774835B (en) 1978-07-26
YU210977A (en) 1982-10-31
FR2380285A1 (fr) 1978-09-08
FR2445834A1 (fr) 1980-08-01
AT355206B (de) 1980-02-25
DK353577A (da) 1978-08-12
AU2786577A (en) 1979-02-15
MY8500446A (en) 1985-12-31
SU856388A3 (ru) 1981-08-15
DE2736471C2 (xx) 1988-09-22
CS199714B2 (en) 1980-07-31
NO800239L (no) 1978-08-14
ATA32778A (de) 1979-09-15
CH636359A5 (de) 1983-05-31
FR2380285B1 (xx) 1981-10-23
IL53830A (en) 1982-07-30
IL59527A0 (en) 1980-06-30
AT356270B (de) 1980-04-25
BE858433A (fr) 1978-01-02
NO772779L (no) 1978-08-14
SG9484G (en) 1984-08-03
FR2384783A1 (fr) 1978-10-20
SE446536B (sv) 1986-09-22
DK155944C (da) 1989-12-04

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Legal Events

Date Code Title Description
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: FARMITALIA CARLO ERBA S.P.A.

BC A request for examination has been filed
A85 Still pending on 85-01-01
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: ERBAMONT INDUSTRIALE S.R.L.

DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: ERBA S.R.L. FARMITALIA CARLO -

BV The patent application has lapsed