DK353577A - 7-acylamido-3-cephem-4-carboxylsyrederivater samt fremgangsmaade til fremstilling deraf - Google Patents

7-acylamido-3-cephem-4-carboxylsyrederivater samt fremgangsmaade til fremstilling deraf

Info

Publication number
DK353577A
DK353577A DK353577A DK353577A DK353577A DK 353577 A DK353577 A DK 353577A DK 353577 A DK353577 A DK 353577A DK 353577 A DK353577 A DK 353577A DK 353577 A DK353577 A DK 353577A
Authority
DK
Denmark
Prior art keywords
acylamido
cephem
procedures
manufacture
carboxylic acid
Prior art date
Application number
DK353577A
Other languages
English (en)
Other versions
DK155944C (da
DK155944B (da
Inventor
G Nannini
E Perrone
D Severino
G Meinardi
G Monti
A Bianchi
A Forgione
C Confalonieri
Original Assignee
Erba F C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba F C filed Critical Erba F C
Publication of DK353577A publication Critical patent/DK353577A/da
Publication of DK155944B publication Critical patent/DK155944B/da
Application granted granted Critical
Publication of DK155944C publication Critical patent/DK155944C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
DK353577A 1977-02-11 1977-08-08 Analogifremgangsmaade til fremstilling af 7-omega-substitueretethylen(cis)-thio-acetamido)-3-cephem-4-carboxylsyrederivater. DK155944C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20173/77A IT1075277B (it) 1977-02-11 1977-02-11 Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
IT2017377 1977-02-11

Publications (3)

Publication Number Publication Date
DK353577A true DK353577A (da) 1978-08-12
DK155944B DK155944B (da) 1989-06-05
DK155944C DK155944C (da) 1989-12-04

Family

ID=11164407

Family Applications (2)

Application Number Title Priority Date Filing Date
DK353577A DK155944C (da) 1977-02-11 1977-08-08 Analogifremgangsmaade til fremstilling af 7-omega-substitueretethylen(cis)-thio-acetamido)-3-cephem-4-carboxylsyrederivater.
DK11578A DK11578A (da) 1977-02-11 1978-01-10 Fremgangsmaade til fremstilling af heteromonocykliske og heterobicykliske derivater af umaettet 7-acylamido-3-cephem-4-carboxylsyre

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11578A DK11578A (da) 1977-02-11 1978-01-10 Fremgangsmaade til fremstilling af heteromonocykliske og heterobicykliske derivater af umaettet 7-acylamido-3-cephem-4-carboxylsyre

Country Status (29)

Country Link
US (3) US4154830A (da)
JP (2) JPS5398991A (da)
AT (2) AT355206B (da)
AU (2) AU512934B2 (da)
BE (2) BE858433A (da)
CA (2) CA1103237A (da)
CH (3) CH632513A5 (da)
CS (3) CS196381B2 (da)
CY (1) CY1234A (da)
DE (2) DE2736471A1 (da)
DK (2) DK155944C (da)
FI (2) FI65259C (da)
FR (3) FR2380285A1 (da)
GB (4) GB1590610A (da)
GR (2) GR71901B (da)
HK (1) HK55284A (da)
HU (2) HU177596B (da)
IL (3) IL52708A0 (da)
IT (1) IT1075277B (da)
MY (1) MY8500446A (da)
NL (2) NL7708943A (da)
NO (4) NO152654C (da)
NZ (2) NZ184889A (da)
PH (1) PH16946A (da)
SE (4) SE7709002L (da)
SG (1) SG9484G (da)
SU (4) SU845788A3 (da)
YU (1) YU40307B (da)
ZA (2) ZA774835B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
JPS5593413A (en) * 1979-01-11 1980-07-15 Osaka Gas Co Ltd Lining method for inner surface of pipe
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4405617A (en) * 1980-02-11 1983-09-20 Fujisawa Pharmaceutical Co., Ltd. 3-(Propynyltetrazol)thiomethyl-3-cephems
GB2076803B (en) * 1980-05-16 1984-02-08 Erba Farmitalia Substituted 7-(a-oxy-imino-acetamido)-cephalosporins and process for their preparation
GB2186875A (en) * 1983-10-31 1987-08-26 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
ATE103923T1 (de) * 1985-12-13 1994-04-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
JPH0544294Y2 (da) * 1986-06-10 1993-11-10
JPH05504767A (ja) * 1990-01-12 1993-07-22 ザ・ダウ・ケミカル・カンパニー 置換３―チオ―２―プロピンニトリルを含んだ組成物及びその工業用抗微生物物質としての使用
US5198445A (en) * 1990-01-12 1993-03-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials
US5126349A (en) * 1990-01-12 1992-06-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5155119A (en) * 1992-03-05 1992-10-13 The Dow Chemical Company 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials
US5157051A (en) * 1992-03-05 1992-10-20 The Dow Chemical Company Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents
US5206227A (en) * 1992-06-02 1993-04-27 The Dow Chemical Company Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials
JP3115455B2 (ja) * 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
SE9802974D0 (sv) 1998-09-03 1998-09-03 Astra Ab New crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
US3883520A (en) * 1973-08-17 1975-05-13 Smithkline Corp Substituted mercaptoacetamidocephalosporins
AU1303576A (en) * 1975-04-21 1977-10-20 Erba Carlo Spa Cephalosporins
ZA767084B (en) * 1975-12-16 1977-10-26 Erba Carlo Spa Thiadiazolyl derivatives of 7-acylamido 3-cephem-4-carboxylic acid and process for their preparation
US4057631A (en) * 1976-09-02 1977-11-08 Smithkline Corporation 7-(α-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-cephem-4-carboxylic acids
US4079134A (en) * 1976-09-24 1978-03-14 Smithkline Corporation 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
NZ184889A (en) 1979-07-11
GB1590610A (en) 1981-06-03
SE8000110L (sv) 1980-01-08
CS196381B2 (en) 1980-03-31
US4172892A (en) 1979-10-30
IL53830A0 (en) 1978-04-30
SG9484G (en) 1984-08-03
JPS6153359B2 (da) 1986-11-17
CH632513A5 (de) 1982-10-15
FI780437A (fi) 1978-08-12
YU40307B (en) 1985-12-31
NO152654C (no) 1985-10-30
DK155944C (da) 1989-12-04
AU512934B2 (en) 1980-11-06
CS199713B2 (en) 1980-07-31
JPS5398991A (en) 1978-08-29
SU753361A3 (ru) 1980-07-30
NL7800443A (nl) 1978-08-15
FI65259B (fi) 1983-12-30
AU3247678A (en) 1979-07-26
GB1582295A (en) 1981-01-07
NL7708943A (nl) 1978-08-15
AU513444B2 (en) 1980-12-04
DE2736471C2 (da) 1988-09-22
NZ186236A (en) 1980-05-08
ZA78181B (en) 1979-08-29
ATA32778A (de) 1979-09-15
AT356270B (de) 1980-04-25
FR2380285A1 (fr) 1978-09-08
FR2384783A1 (fr) 1978-10-20
BE863625A (fr) 1978-08-03
HK55284A (en) 1984-07-27
IL53830A (en) 1982-07-30
CY1234A (en) 1984-06-29
MY8500446A (en) 1985-12-31
NO800239L (no) 1978-08-14
FR2380285B1 (da) 1981-10-23
SU856388A3 (ru) 1981-08-15
BE858433A (fr) 1978-01-02
DK155944B (da) 1989-06-05
FR2445834B1 (da) 1983-10-21
CA1103237A (en) 1981-06-16
SE8002904L (sv) 1980-04-18
FI65259C (fi) 1984-04-10
IL59527A0 (en) 1980-06-30
NO772779L (no) 1978-08-14
CA1108603A (en) 1981-09-08
CH634330A5 (de) 1983-01-31
HU177596B (en) 1981-11-28
FI772411A (fi) 1978-08-12
YU210977A (en) 1982-10-31
DK11578A (da) 1978-08-12
NO780074L (no) 1978-08-14
SU904524A3 (ru) 1982-02-07
FR2384783B1 (da) 1982-12-03
JPS53121788A (en) 1978-10-24
CH636359A5 (de) 1983-05-31
SU845788A3 (ru) 1981-07-07
GB1597262A (en) 1981-09-03
NO152654B (no) 1985-07-22
AT355206B (de) 1980-02-25
US4388314A (en) 1983-06-14
SE7800292L (sv) 1978-08-12
GR71901B (da) 1983-08-11
FR2445834A1 (fr) 1980-08-01
HU178918B (en) 1982-07-28
SE7709002L (sv) 1978-08-12
US4154830A (en) 1979-05-15
DE2736471A1 (de) 1978-08-17
ZA774835B (en) 1978-07-26
IT1075277B (it) 1985-04-22
ATA585677A (de) 1979-07-15
CS199714B2 (en) 1980-07-31
IL52708A0 (en) 1977-10-31
AU2786577A (en) 1979-02-15
PH16946A (en) 1984-04-24
GR72589B (da) 1983-11-18
GB1597261A (en) 1981-09-03
DE2801644A1 (de) 1978-08-17
NO794101L (no) 1978-08-14
SE446536B (sv) 1986-09-22

Similar Documents

Publication Publication Date Title
DK541878A (da) Phthalazin-4-yleddikesyrederivater
DK20979A (da) 4-amino-5-alkylsulfonyl-0-anisamid-derivater samt fremgangsmaade til fremstilling deraf
DK282880A (da) Aminoalkylbenzen-derivater samt fremgangsmaade til fremstilling deraf
SE7806601L (sv) Granuleringsforfarande
DK353577A (da) 7-acylamido-3-cephem-4-carboxylsyrederivater samt fremgangsmaade til fremstilling deraf
DK42778A (da) Imidazol- og friazolderivater samt fremgangsmaade til fremstilling deraf
DK291180A (da) Indolizinderivater samt fremgangsmaade til fremstilling deraf
DK147378A (da) Imidazodiazepinderivater samt fremgangsmaade til fremstilling deraf
DK324078A (da) N-carloxyalkan-aminoalkan-polyhosphonsyrer og alkalimetalsalte deraf samt fremgangsmaade til fremstilling deraf
DK37278A (da) Meta-sulfonamido-benzamid-derivater samt fremgangsmaade til fremstilling deraf
SE7811454L (sv) Forfarande for framstellning av n-alfa-alkyl-resp n-alfa-arylsulfonylerade omega-amidinofenyl-alfa-aminoalkylkarbonsyraamider
DK94880A (da) D-2-hydroxy-4-methylmercaptosmoersyrederivater fremgangsmaade til fremstilling heraf samt anvendelse heraf
DK161105C (da) Bakteriophag samt fremgangsmaade til fremstilling deraf
DK150778A (da) Prostanderivater og fremgangsmaade til fremstilling heraf
DK537677A (da) Propionsyrederivater samt fremgangsmaade til deres fremstilling
DK281377A (da) Joderede isophthalamsyrederivater og fremgangsmade til fremstilling deraf
DK545077A (da) Thiooximcephalosporin- og penicillinderivater samt fremgangsmaader til fremstilling deraf
DK501880A (da) Cyclopropancarboxylsyreesterderivater
SE7704322L (sv) Tiokarbamidderivat samt forfarande for framstellning derav
DK303178A (da) Benzylpyrimidiner samt fremgangsmaade til fremstilling deraf
FI781628A (fi) Foereningar av pregnanserien med en syrefunktion i 19-staellningen foerfaranden foer deras framstaellning samt farmaceutiska preparat innehaollande dessa foereningar
DK38778A (da) Azacycloalkaner azacycloalkener og derivater deraf samt fremgangsmaade til fremstilling deraf
NO150366C (no) Traadtau samt framgangsmaate for framstilling av dette
DK137778A (da) Prostansyrederivater samt deres fremstilling og anvendelse
DK292777A (da) Prostansyrederivater og fremgangsmade til fremstilling heraf

Legal Events

Date Code Title Description
PBP Patent lapsed