ATE103923T1 - Antibakterielle verbindungen, ihre herstellung und verwendung. - Google Patents

Antibakterielle verbindungen, ihre herstellung und verwendung.

Info

Publication number
ATE103923T1
ATE103923T1 AT86117112T AT86117112T ATE103923T1 AT E103923 T1 ATE103923 T1 AT E103923T1 AT 86117112 T AT86117112 T AT 86117112T AT 86117112 T AT86117112 T AT 86117112T AT E103923 T1 ATE103923 T1 AT E103923T1
Authority
AT
Austria
Prior art keywords
group
sup
hydrogen
sub
preparation
Prior art date
Application number
AT86117112T
Other languages
English (en)
Inventor
Tatsuo Nishimura
Yoshinobu Yoshimura
Akio Miyake
Naoto Hashimoto
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE103923T1 publication Critical patent/ATE103923T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT86117112T 1985-12-13 1986-12-09 Antibakterielle verbindungen, ihre herstellung und verwendung. ATE103923T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28172485 1985-12-13
EP86117112A EP0225634B1 (de) 1985-12-13 1986-12-09 Antibakterielle Verbindungen, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE103923T1 true ATE103923T1 (de) 1994-04-15

Family

ID=17643095

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86117112T ATE103923T1 (de) 1985-12-13 1986-12-09 Antibakterielle verbindungen, ihre herstellung und verwendung.

Country Status (6)

Country Link
US (1) US4839351A (de)
EP (1) EP0225634B1 (de)
JP (1) JPH0699450B2 (de)
AT (1) ATE103923T1 (de)
CA (1) CA1277978C (de)
DE (1) DE3689762T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3803169A1 (de) * 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
DE3939533A1 (de) * 1989-11-30 1991-06-06 Bayer Ag Neue cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ES2069137T3 (es) * 1990-07-30 1995-05-01 Takeda Chemical Industries Ltd Derivados de imidazopiridina y su uso.
JP3115455B2 (ja) * 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
EP2544086A1 (de) 2001-09-14 2013-01-09 Canon Kabushiki Kaisha Drucksteuerung unter Verwendung eines vitrtuellen Druckers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3814755A (en) * 1972-08-30 1974-06-04 Bristol Myers Co 7-(omikron-aminomethylphenylacetamido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
US3813391A (en) * 1972-09-06 1974-05-28 Bristol Myers Co 7-(beta-(o-aminomethylphenyl)propion-amido)-3-(tetrazolo(4,5-b)pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
GB1599469A (en) * 1978-04-21 1981-10-07 Cusi Lab Antibiotics of the group of cephalosporins
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
US4463003A (en) * 1982-12-22 1984-07-31 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.

Also Published As

Publication number Publication date
DE3689762D1 (de) 1994-05-11
JPS62277393A (ja) 1987-12-02
EP0225634A3 (en) 1988-11-02
US4839351A (en) 1989-06-13
EP0225634A2 (de) 1987-06-16
DE3689762T2 (de) 1994-08-18
EP0225634B1 (de) 1994-04-06
CA1277978C (en) 1990-12-18
JPH0699450B2 (ja) 1994-12-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties