IL52708A0 - Unsaturated derivatives of 7-acylamide-3-cephem-4-carboxylic acid and process for their preparation - Google Patents

Unsaturated derivatives of 7-acylamide-3-cephem-4-carboxylic acid and process for their preparation

Info

Publication number
IL52708A0
IL52708A0 IL52708A IL5270877A IL52708A0 IL 52708 A0 IL52708 A0 IL 52708A0 IL 52708 A IL52708 A IL 52708A IL 5270877 A IL5270877 A IL 5270877A IL 52708 A0 IL52708 A0 IL 52708A0
Authority
IL
Israel
Prior art keywords
acylamide
cephem
preparation
carboxylic acid
unsaturated derivatives
Prior art date
Application number
IL52708A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL52708A0 publication Critical patent/IL52708A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL52708A 1977-02-11 1977-08-12 Unsaturated derivatives of 7-acylamide-3-cephem-4-carboxylic acid and process for their preparation IL52708A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20173/77A IT1075277B (it) 1977-02-11 1977-02-11 Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
IL52708A0 true IL52708A0 (en) 1977-10-31

Family

ID=11164407

Family Applications (3)

Application Number Title Priority Date Filing Date
IL52708A IL52708A0 (en) 1977-02-11 1977-08-12 Unsaturated derivatives of 7-acylamide-3-cephem-4-carboxylic acid and process for their preparation
IL53830A IL53830A (en) 1977-02-11 1978-01-17 Heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acids,their preparation and pharmaceutical or veterinary compositions comprising them
IL59527A IL59527A0 (en) 1977-02-11 1980-03-05 Heteromonocyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and process for their preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL53830A IL53830A (en) 1977-02-11 1978-01-17 Heterobicyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acids,their preparation and pharmaceutical or veterinary compositions comprising them
IL59527A IL59527A0 (en) 1977-02-11 1980-03-05 Heteromonocyclic derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and process for their preparation

Country Status (29)

Country Link
US (3) US4154830A (it)
JP (2) JPS5398991A (it)
AT (2) AT355206B (it)
AU (2) AU512934B2 (it)
BE (2) BE858433A (it)
CA (2) CA1103237A (it)
CH (3) CH632513A5 (it)
CS (3) CS196381B2 (it)
CY (1) CY1234A (it)
DE (2) DE2736471A1 (it)
DK (2) DK155944C (it)
FI (2) FI65259C (it)
FR (3) FR2380285A1 (it)
GB (4) GB1582295A (it)
GR (2) GR71901B (it)
HK (1) HK55284A (it)
HU (2) HU177596B (it)
IL (3) IL52708A0 (it)
IT (1) IT1075277B (it)
MY (1) MY8500446A (it)
NL (2) NL7708943A (it)
NO (4) NO152654C (it)
NZ (2) NZ184889A (it)
PH (1) PH16946A (it)
SE (4) SE7709002L (it)
SG (1) SG9484G (it)
SU (4) SU845788A3 (it)
YU (1) YU40307B (it)
ZA (2) ZA774835B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
JPS5593413A (en) * 1979-01-11 1980-07-15 Osaka Gas Co Ltd Lining method for inner surface of pipe
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4405617A (en) * 1980-02-11 1983-09-20 Fujisawa Pharmaceutical Co., Ltd. 3-(Propynyltetrazol)thiomethyl-3-cephems
GB2076803B (en) * 1980-05-16 1984-02-08 Erba Farmitalia Substituted 7-(a-oxy-imino-acetamido)-cephalosporins and process for their preparation
GB2186875A (en) * 1983-10-31 1987-08-26 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
ATE103923T1 (de) * 1985-12-13 1994-04-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
JPH0544294Y2 (it) * 1986-06-10 1993-11-10
AU7226591A (en) * 1990-01-12 1991-08-21 Dow Chemical Company, The Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5198445A (en) * 1990-01-12 1993-03-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as industrial antimicrobials
US5126349A (en) * 1990-01-12 1992-06-30 The Dow Chemical Company Composition and use of substituted 3-thio-2-propynenitriles as an industrial antimicrobial
US5157051A (en) * 1992-03-05 1992-10-20 The Dow Chemical Company Composition and use of 3-thiocyano-2-halo-2-propenenitriles as antimicrobial agents
US5155119A (en) * 1992-03-05 1992-10-13 The Dow Chemical Company 3-(2-pyridinylthio)-N-oxide, 2-halo-2-propenenitrile compounds useful as antimicrobials
US5206227A (en) * 1992-06-02 1993-04-27 The Dow Chemical Company Composition and use of phosphonic acid, (2-halo-2-cyanoethenyl)-dialkyl esters as antimicrobials
JP3115455B2 (ja) * 1992-12-18 2000-12-04 明治製菓株式会社 新規セファロスポリン誘導体
SE9802974D0 (sv) 1998-09-03 1998-09-03 Astra Ab New crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1075277B (it) * 1977-02-11 1985-04-22 Erba Carlo Spa Derivati insaturi e epossidici dell'acio 7-acilamido-3-cefem-4-carbossilico e procedimento per la loro preparazione
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
US3883520A (en) * 1973-08-17 1975-05-13 Smithkline Corp Substituted mercaptoacetamidocephalosporins
AU1303576A (en) * 1975-04-21 1977-10-20 Erba Carlo Spa Cephalosporins
ZA767084B (en) * 1975-12-16 1977-10-26 Erba Carlo Spa Thiadiazolyl derivatives of 7-acylamido 3-cephem-4-carboxylic acid and process for their preparation
US4057631A (en) * 1976-09-02 1977-11-08 Smithkline Corporation 7-(α-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-cephem-4-carboxylic acids
US4079134A (en) * 1976-09-24 1978-03-14 Smithkline Corporation 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
SE7800292L (sv) 1978-08-12
CY1234A (en) 1984-06-29
CS196381B2 (en) 1980-03-31
AU2786577A (en) 1979-02-15
DK155944B (da) 1989-06-05
AT355206B (de) 1980-02-25
BE858433A (fr) 1978-01-02
FI65259C (fi) 1984-04-10
PH16946A (en) 1984-04-24
CH632513A5 (de) 1982-10-15
IL53830A0 (en) 1978-04-30
CH636359A5 (de) 1983-05-31
FR2380285B1 (it) 1981-10-23
GB1590610A (en) 1981-06-03
US4172892A (en) 1979-10-30
CA1108603A (en) 1981-09-08
AT356270B (de) 1980-04-25
IT1075277B (it) 1985-04-22
SE7709002L (sv) 1978-08-12
HK55284A (en) 1984-07-27
DK11578A (da) 1978-08-12
DK353577A (da) 1978-08-12
CS199713B2 (en) 1980-07-31
CH634330A5 (de) 1983-01-31
US4388314A (en) 1983-06-14
YU40307B (en) 1985-12-31
NO152654B (no) 1985-07-22
YU210977A (en) 1982-10-31
JPS5398991A (en) 1978-08-29
FR2445834B1 (it) 1983-10-21
ATA585677A (de) 1979-07-15
FI65259B (fi) 1983-12-30
AU513444B2 (en) 1980-12-04
JPS53121788A (en) 1978-10-24
MY8500446A (en) 1985-12-31
DE2801644A1 (de) 1978-08-17
NO800239L (no) 1978-08-14
DE2736471C2 (it) 1988-09-22
NO794101L (no) 1978-08-14
NO780074L (no) 1978-08-14
SU845788A3 (ru) 1981-07-07
CS199714B2 (en) 1980-07-31
DE2736471A1 (de) 1978-08-17
SG9484G (en) 1984-08-03
SE8000110L (sv) 1980-01-08
JPS6153359B2 (it) 1986-11-17
NO152654C (no) 1985-10-30
HU177596B (en) 1981-11-28
GB1597261A (en) 1981-09-03
GR72589B (it) 1983-11-18
SE446536B (sv) 1986-09-22
NO772779L (no) 1978-08-14
FR2384783A1 (fr) 1978-10-20
US4154830A (en) 1979-05-15
AU3247678A (en) 1979-07-26
FR2384783B1 (it) 1982-12-03
FR2380285A1 (fr) 1978-09-08
GB1597262A (en) 1981-09-03
ATA32778A (de) 1979-09-15
FI780437A (fi) 1978-08-12
HU178918B (en) 1982-07-28
FR2445834A1 (fr) 1980-08-01
NZ184889A (en) 1979-07-11
SU856388A3 (ru) 1981-08-15
GB1582295A (en) 1981-01-07
SE8002904L (sv) 1980-04-18
DK155944C (da) 1989-12-04
FI772411A (fi) 1978-08-12
ZA774835B (en) 1978-07-26
SU904524A3 (ru) 1982-02-07
AU512934B2 (en) 1980-11-06
IL59527A0 (en) 1980-06-30
IL53830A (en) 1982-07-30
NL7800443A (nl) 1978-08-15
NL7708943A (nl) 1978-08-15
ZA78181B (en) 1979-08-29
NZ186236A (en) 1980-05-08
CA1103237A (en) 1981-06-16
GR71901B (it) 1983-08-11
BE863625A (fr) 1978-08-03
SU753361A3 (ru) 1980-07-30

Similar Documents

Publication Publication Date Title
GR65303B (en) Process for preparation of phthalazin-4-ylacetic acid derivatives
DE2860863D1 (en) 3- and 4-azidophthalic acid derivatives and process for their preparation
RO75478B (ro) Procedeu pentru prepararea unor derivati ai acidului alfa-fenoxipropionic
YU98186A (en) Process for preparation of derivatives of phenoxyalkylcarboxylic acid
GR60800B (en) Preparation process of acetic acid derivatives
IL53830A0 (en) Derivatives of unsaturated 7-acylamido-3-cephem-4-carboxylic acid and process for their preparation
EG12936A (en) Process for preparing of thiazolylcinnamic acid nitrilles and their use as pesticides
GR61726B (en) Preparation process of novel isoquinoleine derivatives
GB2001625B (en) Process for preparation of 3-acylamino-4-homoisotwistane
PT68946A (en) Process for the preparation of salicylic acid and derivatives thereof
DE2860609D1 (en) Bis-azido-phthalic acid derivatives and process for their preparation
GB1554310A (en) Process for the preparation of 5-oxo-hexanoic acid and derivatives thereof
PH17068A (en) 5-cyano-1-methylpyrrole 2-acetic acid and process of preparation
IL51057A0 (en) Thiadiazolyl derivatives of 7-acylamido-3-cephem-4-carboxylic acid and process for their preparation
IL54206A0 (en) Process for the preparation of , -dialkoxycarboxylic acid derivatives
IL54585A0 (en) 5-sulfamoyl-orthanilic acids and process for their preparation
GB2007649B (en) Derivatives of arylalcanoic acid and processes for making them
IL49449A0 (en) Bicyclic derivatives of 7-acylamido-3-cephem-4-carboxylic acid and process for their preparation
GR60029B (en) Analogs of prostanic acids and process for their preparation
GR64425B (en) Derivatives of 3-carboxyphenylesacetic acid and method for the preparation thereof
GR65659B (en) Method for preparation of derivatives of cloroulanic acid
GB2006763B (en) Derivatives of 4-cyclohexyl-1-naphtaleneacetic acid process for their preparation and their use as drugs
DE2861500D1 (en) Bisphosphinic acid anhydrides and process for its preparation
KE3374A (en) Unsaturated-thio-derivatives of 7-acetamido-3-cephem-4-carboxylic acid and process for their preparation
DE2861280D1 (en) Process for the preparation of alpha-substituted-thien-3-ylacetic acid and derivatives thereof

Legal Events

Date Code Title Description
RH Patent void