PE75399A1 - Granulos entericos de fluoxetina - Google Patents
Granulos entericos de fluoxetinaInfo
- Publication number
- PE75399A1 PE75399A1 PE1998000430A PE00043098A PE75399A1 PE 75399 A1 PE75399 A1 PE 75399A1 PE 1998000430 A PE1998000430 A PE 1998000430A PE 00043098 A PE00043098 A PE 00043098A PE 75399 A1 PE75399 A1 PE 75399A1
- Authority
- PE
- Peru
- Prior art keywords
- fluoxetine
- granules
- optional
- layer
- hydroxypropylmethyllchell
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
CARACTERIZADO PORQUE COMPRENDE a)NUCLEO DE CLORHIDRATO DE FLUOXETINA DE 20mg A 100 mg, b)CAPA DE SEPARACION OPCIONAL TAL COMO SACAROSA, c)CAPA ENTERICA QUE COMPRENDE SUCCINATO ACETATO DE HIDROXIPROPILMETILCELULOSA (HPMCAS), SE NEUTRALIZAN EL 0%-15% DE LOS GRUPOS SUCCINILO CON AMONIACO; d)CAPA DE TERMINACION OPCIONAL. EL TAMANO MEDIO DE PARTICULA DE FLUOXETINA ES APROXIMADAMENTE 50 um O MENOS. LOS GRANULOS ESTAN CONTENIDOS EN CAPSULAS DE GELATINA. TAMBIEN SE REFIERE A UN PROCEDIMEINTO PARA LA PREPARACION. LA FORMULACION COMPRENDE ADEMAS PINDOLOL PUEDE SER UTIL PARA EL TRATAMIENTO DE DEPRESION, TRASTORNO OBSESIVO COMPULSIVO, BULIMIA, DOLOR, TRASTORNOS DE PERSONALIDAD
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/867,196 US5910319A (en) | 1997-05-29 | 1997-05-29 | Fluoxetine enteric pellets and methods for their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
PE75399A1 true PE75399A1 (es) | 1999-08-17 |
Family
ID=25349313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1998000430A PE75399A1 (es) | 1997-05-29 | 1998-05-28 | Granulos entericos de fluoxetina |
Country Status (46)
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2752732B1 (fr) * | 1996-08-28 | 1998-11-20 | Pf Medicament | Forme galenique a liberation prolongee de milnacipran |
DK1178780T3 (da) * | 1999-05-20 | 2007-11-12 | Elan Corp Plc | Multipartikelformige formuleringer til kontrolleret frigivelse af selektiv serotoningenoptagelseshæmmer |
IE990406A1 (en) | 1999-05-20 | 2000-12-27 | Elan Corp Plc | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
ES2162560B1 (es) * | 1999-06-25 | 2002-07-16 | Rodriguez Concepcion Pena | Uso de fluoxetina, paroxetina y otros isrs para la fabricacion de medicamentos con el fin de aumentar la capacidad de abstenerse de substancias o actividades que crean dependencia. |
EP1889614A3 (en) | 1999-09-03 | 2010-09-22 | APBI Holdings, LLC | Methods of using rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction |
CN1094347C (zh) * | 1999-11-15 | 2002-11-20 | 广东药学院药物研究所 | 一种治疗前列腺良性增生症的控释微丸及其制备方法 |
US6273260B1 (en) | 2000-03-08 | 2001-08-14 | Eli Lilly And Company | Pharmaceutical packaging system |
ES2185452B2 (es) * | 2000-08-01 | 2004-03-16 | Cinfa S A Lab | Composicion farmaceutica de fluoxetina en comprimido dispersable recubierto y su proceso de fabricacion. |
JP4181738B2 (ja) * | 2000-08-25 | 2008-11-19 | 信越化学工業株式会社 | 腸溶性コーティング製剤の製造方法 |
US6482440B2 (en) * | 2000-09-21 | 2002-11-19 | Phase 2 Discovery, Inc. | Long acting antidepressant microparticles |
WO2002038126A2 (en) * | 2000-11-08 | 2002-05-16 | Aeromatic-Fielder Ag | A process for production of particles for pharmaceutical compositions having increased bioavailability |
WO2003013480A1 (en) | 2001-08-06 | 2003-02-20 | Dr. Reddy's Laboratories Ltd. | Improved enteric formulation of fluoxetin |
US20040170688A1 (en) * | 2001-08-06 | 2004-09-02 | Deshmukh Abhijit Mukund | Enteric formulation of fluoxetin |
US20040220153A1 (en) * | 2002-09-24 | 2004-11-04 | Jost-Price Edward Roydon | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
WO2004058228A1 (en) * | 2002-12-24 | 2004-07-15 | Lupin Limited | Enteric coated fluoxetine composition |
US8614247B2 (en) * | 2003-04-10 | 2013-12-24 | Institut National De La Sante Et De La Recherche Medicale | Methods for preventing, attenuating or treating pulmonary hypertension using a serotonin transporter inhibitor, and pharmaceutical compositions for the treatment thereof |
JP4901474B2 (ja) | 2003-05-30 | 2012-03-21 | ランバクシー ラボラトリーズ リミテッド | 置換ピロール誘導体 |
US20050176693A1 (en) * | 2003-08-12 | 2005-08-11 | Boissonneault Roger M. | Method of intermittent administration of a pharmaceutical for the treatment of conditions associated with a female's menstrual cycle |
EP1699458A4 (en) * | 2003-12-30 | 2012-04-25 | Reddys Lab Ltd Dr | PHARMACEUTICAL COMPOSITION |
WO2005105045A1 (ja) * | 2004-04-30 | 2005-11-10 | Astellas Pharma Inc. | 経口投与用時限放出型粒子状医薬組成物及び該組成物を含有する口腔内速崩壊錠 |
KR100920856B1 (ko) * | 2004-11-30 | 2009-10-09 | (주)아모레퍼시픽 | 선택적 세로토닌 재흡수 억제제의 연장방출 제제 및 그제조방법 |
JP2007523213A (ja) * | 2004-12-23 | 2007-08-16 | テバ ファーマシューティカル インダストリーズ リミティド | 医薬的に許容できるデュロキセチンの塩及びその中間体の調製方法 |
AU2006274565B2 (en) * | 2005-08-02 | 2012-05-17 | Lupin Limited | Novel controlled release compositions of selective serotonin reuptake inhibitors |
KR101329112B1 (ko) | 2005-11-08 | 2013-11-14 | 랜박시 래보러터리스 리미티드 | (3r,5r)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법 |
CA2629800A1 (en) * | 2005-11-23 | 2007-05-31 | Thomas G. Gant | Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity |
US7759500B2 (en) * | 2005-12-05 | 2010-07-20 | Teva Pharmaceutical Industries Ltd. | 2-(N-methyl-propanamine)-3-(2-naphthol)thiophene, an impurity of duloxetine hydrochloride |
CN101426478A (zh) * | 2006-02-24 | 2009-05-06 | 特瓦制药工业有限公司 | 氟伐他汀钠药物组合物 |
CN101057837B (zh) * | 2006-04-20 | 2010-12-22 | 湖南九典制药有限公司 | 一种右旋酮洛芬肠溶微丸及制备方法 |
EP2016066A4 (en) * | 2006-05-10 | 2010-11-24 | Reddys Lab Ltd Dr | PROCESS FOR PREPARING DULOXETINE |
BRPI0711606A2 (pt) * | 2006-05-22 | 2012-02-14 | Teva Pharma | formulações de hidrocloreto de duloxetina de liberação retardada |
US20100297226A1 (en) * | 2006-06-01 | 2010-11-25 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
JP5052051B2 (ja) * | 2006-06-16 | 2012-10-17 | トーアエイヨー株式会社 | 腸溶性顆粒剤及びその製造方法 |
US20090252787A1 (en) * | 2006-07-28 | 2009-10-08 | Dr. Reddy's Laboratories Ltd. | Granular pharmaceutical compositions |
US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
US20090175935A1 (en) * | 2006-08-14 | 2009-07-09 | Torrent Research Ltd. | Pharmaceutical compositions of duloxetine |
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US20080226711A1 (en) * | 2007-03-12 | 2008-09-18 | Torrent Pharmaceuticals Ltd. | Pharmaceutical compositions of duloxetine |
US20090226517A1 (en) * | 2008-02-06 | 2009-09-10 | Vinita Umashankar Vyas | Pharmaceutical formulations comprising duloxetine |
SI2317852T1 (sl) | 2008-07-16 | 2015-04-30 | Richter Gedeon Nyrt. | Farmacevtske formulacije, ki vsebujejo ligande dopaminskega receptorja |
WO2010026993A1 (ja) * | 2008-09-03 | 2010-03-11 | 武田薬品工業株式会社 | 製剤における吸収性改善方法および吸収性が改善された製剤 |
CN101804145B (zh) * | 2009-02-12 | 2012-11-14 | 杭州赛利药物研究所有限公司 | 一种大蒜油肠溶微丸胶囊及其制备方法 |
US20120207825A1 (en) * | 2009-09-17 | 2012-08-16 | Sunilendu Bhushan Roy | Pharmaceutical compositions for reducing alcohol-induced dose dumping |
EP2540318B1 (en) | 2010-02-22 | 2018-10-24 | Daiichi Sankyo Company, Limited | Sustained-release solid preparation for oral use |
ES2728850T3 (es) * | 2012-05-02 | 2019-10-29 | Capsugel Belgium Nv | Dispersiones acuosas de acetato acetato succinato de hidroxipropilmetilcelulosa (HPMCAS) |
CN102716084B (zh) * | 2012-06-29 | 2013-09-25 | 海南美大制药有限公司 | 盐酸氟西汀脂质体固体制剂 |
ES2706994T3 (es) | 2012-09-03 | 2019-04-02 | Daiichi Sankyo Co Ltd | Composición farmacéutica de liberación prolongada de administración oral que contiene clorhidrato de hidromorfona |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2015179073A1 (en) * | 2014-05-20 | 2015-11-26 | Dow Global Technologies Llc | Capsule shells comprising an esterified cellulose ether |
WO2015179072A1 (en) | 2014-05-20 | 2015-11-26 | Dow Global Technologies Llc | Dispersion comprising a partially neutralized esterified cellulose ether |
US10564114B2 (en) * | 2014-06-07 | 2020-02-18 | Structure-Ase Incorporated | Method for the detection and/or diagnosis of eating disorders and malnutrition using X-ray diffraction |
US10471152B2 (en) | 2014-08-29 | 2019-11-12 | Capsugel Belgium Nv | Colloidal dispersion comprising HPMCAS |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
US11274087B2 (en) | 2016-07-08 | 2022-03-15 | Richter Gedeon Nyrt. | Industrial process for the preparation of cariprazine |
EP3609578A4 (en) | 2017-04-13 | 2021-03-10 | Chase Therapeutics Corporation | PHARMACEUTICAL COMBINATION AND ITS USE FOR THE TREATMENT OF SYNUCLEINOPATHIES |
HUP1700253A1 (hu) | 2017-06-13 | 2019-01-28 | Richter Gedeon Nyrt | Szilárd orális gyógyszerkészítmények |
CN107898942B (zh) * | 2017-11-24 | 2021-01-26 | 一力制药(罗定)有限公司 | 一种感冒清热胶囊及其制备方法 |
US11547707B2 (en) | 2019-04-10 | 2023-01-10 | Richter Gedeon Nyrt. | Carbamoyl cyclohexane derivatives for treating autism spectrum disorder |
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-
1997
- 1997-05-29 US US08/867,196 patent/US5910319A/en not_active Ceased
-
1998
- 1998-04-13 IL IL12407398A patent/IL124073A/en not_active IP Right Cessation
- 1998-04-14 RU RU98106998/14A patent/RU2164405C2/ru active
- 1998-04-14 RO RO98-00869A patent/RO120043B1/ro unknown
- 1998-04-14 CA CA002234826A patent/CA2234826C/en not_active Expired - Lifetime
- 1998-04-15 CZ CZ19981143A patent/CZ290582B6/cs not_active IP Right Cessation
- 1998-04-15 NZ NZ330192A patent/NZ330192A/xx not_active IP Right Cessation
- 1998-04-15 HU HU9800882A patent/HUP9800882A3/hu not_active Application Discontinuation
- 1998-04-15 GB GB9807939A patent/GB2325623B/en not_active Expired - Lifetime
- 1998-04-15 ZA ZA9803173A patent/ZA983173B/xx unknown
- 1998-04-15 RS YUP-165/98A patent/RS49827B/sr unknown
- 1998-04-15 UA UA98041929A patent/UA48193C2/uk unknown
- 1998-04-16 MY MYPI98001702A patent/MY118139A/en unknown
- 1998-04-16 FI FI980846A patent/FI119971B/fi active IP Right Grant
- 1998-04-17 SE SE9801336A patent/SE522914C2/sv not_active IP Right Cessation
- 1998-04-17 SG SG1998000871A patent/SG72805A1/en unknown
- 1998-04-20 KR KR1019980014014A patent/KR100549473B1/ko not_active IP Right Cessation
- 1998-04-22 LT LT98-058A patent/LT4477B/lt not_active IP Right Cessation
- 1998-04-24 JP JP15350198A patent/JP3210288B2/ja not_active Expired - Lifetime
- 1998-04-24 CN CNB981087787A patent/CN1161109C/zh not_active Expired - Lifetime
- 1998-04-28 IT IT98MI000908A patent/ITMI980908A1/it unknown
- 1998-04-28 ES ES009800899A patent/ES2161574B1/es not_active Expired - Fee Related
- 1998-04-28 SV SV1998000052A patent/SV1998000052A/es unknown
- 1998-04-29 SI SI9800128A patent/SI9800128B/sl unknown
- 1998-05-01 PL PL326134A patent/PL192293B1/pl unknown
- 1998-05-07 AR ARP980102130A patent/AR011728A1/es not_active Application Discontinuation
- 1998-05-08 PT PT102152A patent/PT102152B/pt active IP Right Grant
- 1998-05-11 TW TW087107241A patent/TWI239838B/zh not_active IP Right Cessation
- 1998-05-12 CO CO98026349A patent/CO4940407A1/es unknown
- 1998-05-13 FR FR9806040A patent/FR2763846B1/fr not_active Expired - Lifetime
- 1998-05-14 NO NO19982197A patent/NO317743B1/no not_active IP Right Cessation
- 1998-05-19 BR BR9801989-9A patent/BR9801989A/pt not_active Application Discontinuation
- 1998-05-20 BE BE9800383A patent/BE1011925A3/fr not_active IP Right Cessation
- 1998-05-20 LU LU90245A patent/LU90245B1/fr active
- 1998-05-25 LV LVP-98-121A patent/LV12176B/xx unknown
- 1998-05-26 NL NL1009259A patent/NL1009259C2/nl not_active IP Right Cessation
- 1998-05-26 CH CH01157/98A patent/CH693018A5/de not_active IP Right Cessation
- 1998-05-27 TR TR1998/00937A patent/TR199800937A2/xx unknown
- 1998-05-28 GR GR980100188A patent/GR980100188A/el unknown
- 1998-05-28 ID IDP980791A patent/ID20343A/id unknown
- 1998-05-28 DE DE19823940A patent/DE19823940B4/de not_active Expired - Lifetime
- 1998-05-28 AU AU69048/98A patent/AU726690B2/en not_active Expired
- 1998-05-28 PE PE1998000430A patent/PE75399A1/es not_active Application Discontinuation
- 1998-05-28 DK DK199800728A patent/DK176776B1/da not_active IP Right Cessation
- 1998-05-29 AT AT0093198A patent/AT408068B/de not_active IP Right Cessation
-
1999
- 1999-03-10 US US09/265,610 patent/US5985322A/en not_active Expired - Lifetime
-
2000
- 2000-07-25 CN CNB001222090A patent/CN1212834C/zh not_active Expired - Lifetime
-
2001
- 2001-08-10 HK HK01105581A patent/HK1034902A1/xx not_active IP Right Cessation
-
2002
- 2002-01-28 US US10/058,891 patent/USRE39030E1/en not_active Expired - Lifetime
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