PE20142141A1 - Linea de proceso para la produccion de particulas criodesecadas - Google Patents
Linea de proceso para la produccion de particulas criodesecadasInfo
- Publication number
- PE20142141A1 PE20142141A1 PE2014000480A PE2014000480A PE20142141A1 PE 20142141 A1 PE20142141 A1 PE 20142141A1 PE 2014000480 A PE2014000480 A PE 2014000480A PE 2014000480 A PE2014000480 A PE 2014000480A PE 20142141 A1 PE20142141 A1 PE 20142141A1
- Authority
- PE
- Peru
- Prior art keywords
- particles
- process line
- production
- spray chamber
- criodessed
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000007921 spray Substances 0.000 abstract 3
- 238000001816 cooling Methods 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 230000008014 freezing Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
- F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
Landscapes
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Drying Of Solid Materials (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Oxygen, Ozone, And Oxides In General (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11008057.9A EP2578974A1 (en) | 2011-10-05 | 2011-10-05 | Process line for the production of freeze-dried particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20142141A1 true PE20142141A1 (es) | 2015-01-04 |
Family
ID=46980888
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014000479A PE20141979A1 (es) | 2011-10-05 | 2012-10-04 | Linea de proceso para la produccion de particulas criodesecadas |
| PE2014000480A PE20142141A1 (es) | 2011-10-05 | 2012-10-04 | Linea de proceso para la produccion de particulas criodesecadas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014000479A PE20141979A1 (es) | 2011-10-05 | 2012-10-04 | Linea de proceso para la produccion de particulas criodesecadas |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US9920989B2 (enExample) |
| EP (4) | EP2578974A1 (enExample) |
| JP (2) | JP5728135B2 (enExample) |
| KR (2) | KR101512608B1 (enExample) |
| CN (2) | CN103917842B (enExample) |
| AU (2) | AU2012320854B2 (enExample) |
| BR (2) | BR112014007862B1 (enExample) |
| CA (2) | CA2849802C (enExample) |
| CO (2) | CO6930351A2 (enExample) |
| CR (2) | CR20140159A (enExample) |
| DK (2) | DK2764309T3 (enExample) |
| EA (2) | EA027630B1 (enExample) |
| ES (2) | ES2608478T3 (enExample) |
| HU (2) | HUE029973T2 (enExample) |
| IL (2) | IL231853A0 (enExample) |
| IN (2) | IN2014CN02407A (enExample) |
| MX (2) | MX341894B (enExample) |
| MY (2) | MY151369A (enExample) |
| PE (2) | PE20141979A1 (enExample) |
| PH (2) | PH12014500617A1 (enExample) |
| PL (2) | PL2764309T3 (enExample) |
| SG (2) | SG11201400641QA (enExample) |
| UA (2) | UA111858C2 (enExample) |
| WO (2) | WO2013050162A1 (enExample) |
| ZA (1) | ZA201401930B (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2416790B1 (en) | 2009-04-09 | 2018-05-23 | Entegrion, Inc. | Spray-dried blood products and methods of making same |
| US20110142885A1 (en) | 2009-09-16 | 2011-06-16 | Velico Medical, Inc. | Spray-dried human plasma |
| US20140083628A1 (en) | 2012-09-27 | 2014-03-27 | Velico Medical, Inc. | Spray drier assembly for automated spray drying |
| EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
| EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
| EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
| UA111631C2 (uk) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | Нагрівальний пристрій для роторної барабанної ліофільної сушарки |
| WO2014190992A1 (en) | 2013-05-29 | 2014-12-04 | Gea Process Engineering A/S | Method of providing inline sterile freeze drying of a product in trays accommodated in a trolley, system for carrying out the method, and use of the method |
| JP6166006B1 (ja) * | 2014-07-21 | 2017-07-19 | サノフィ パスツール エスエー | 液滴生成のための液体供給装置 |
| US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
| DE102015105375B4 (de) * | 2015-01-07 | 2016-11-03 | Richard Süverkrüp | Vorrichtung und Verfahren zur Erzeugung monodisperser gefrorener Tropfen |
| US9739532B2 (en) * | 2015-02-04 | 2017-08-22 | Steven F. Baugh | Botanical freeze drying system and method |
| US10465985B2 (en) | 2015-06-01 | 2019-11-05 | Ima Life North America Inc. | Bulk freeze drying using spray freezing and agitated drying with dielectric heating |
| RU2615553C1 (ru) * | 2015-10-15 | 2017-04-05 | Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" | Способ и устройство непрерывной сублимационной сушки жидких продуктов |
| EP3167877A1 (en) | 2015-11-12 | 2017-05-17 | Bayer Pharma Aktiengesellschaft | Method for the production of freeze-dried pellets comprising factor viii |
| CN106705574A (zh) * | 2015-11-17 | 2017-05-24 | 上海东富龙科技股份有限公司 | 一种固体制剂制造设备和方法 |
| JP6666535B2 (ja) * | 2016-01-05 | 2020-03-18 | 株式会社あい・あいエナジーアソシエイツ | 液体の凍結乾燥装置及び凍結乾燥方法 |
| CN105674691B (zh) * | 2016-04-01 | 2017-11-21 | 苏州大学 | 用于收集喷雾冷冻冰球颗粒的双密封式设备及其收集方法 |
| US10369077B2 (en) * | 2017-05-31 | 2019-08-06 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using the same |
| US10507165B2 (en) | 2017-05-31 | 2019-12-17 | Adienne Pharma & Biotech Sa | Multi chamber flexible bag and methods of using same |
| DE102017119649A1 (de) | 2017-08-28 | 2019-02-28 | Richard Süverkrüp | Verfahren zur kontinuierlichen Herstellung gefriergetrockneter Tropfen in einem geschlossenen Gaskreislauf |
| ES2779023T3 (es) * | 2017-10-20 | 2020-08-13 | Martin Christ Gefriertrocknungsanlagen Gmbh | Procedimiento para la determinación a base de presión de un parámetro de producto en un liofilizador, liofilizador y producto de software |
| KR102450460B1 (ko) * | 2017-12-29 | 2022-09-30 | 아주대학교산학협력단 | 초음파 분무기를 이용한 미립구 약제의 양산 시스템 |
| JP7038435B2 (ja) * | 2018-03-13 | 2022-03-18 | 株式会社プリス | 噴霧凍結造粒乾燥粉体製造装置及び噴霧凍結造粒乾燥粉体製造システム |
| CN111065874B (zh) * | 2018-06-08 | 2020-12-29 | 株式会社爱发科 | 真空冻结干燥装置和真空冻结干燥方法 |
| CA3105256A1 (en) | 2018-07-05 | 2020-01-09 | Bayer Aktiengesellschaft | Novel stable high-concentration formulation for anti-fxia antibodies |
| EP3864359B1 (en) | 2018-10-11 | 2023-06-28 | IMA Life North America Inc. | Bulk freeze drying system |
| WO2020161863A1 (ja) * | 2019-02-07 | 2020-08-13 | 株式会社アルバック | 真空凍結乾燥方法及び真空凍結乾燥装置 |
| US11243029B2 (en) * | 2019-04-26 | 2022-02-08 | Purdue Research Foundation | Process monitoring and control for lyophilization using a wireless sensor network |
| CN111207564B (zh) * | 2019-09-30 | 2022-01-04 | 中国科学院上海硅酸盐研究所 | 一种冷冻干燥系统及方法 |
| JP7626766B2 (ja) * | 2019-12-09 | 2025-02-04 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 飲料ペースト |
| JP6777350B1 (ja) | 2020-05-18 | 2020-10-28 | 株式会社エムアイアイ | 真空凍結乾燥装置及び真空凍結乾燥方法 |
| TWI860477B (zh) | 2020-05-18 | 2024-11-01 | 日商Ｍｉｉ股份有限公司 | 真空凍結乾燥裝置及真空凍結乾燥方法 |
| JP6887050B1 (ja) * | 2020-08-07 | 2021-06-16 | 株式会社アルバック | 真空凍結乾燥方法および真空凍結乾燥装置 |
| CN115917232A (zh) * | 2020-08-07 | 2023-04-04 | 株式会社爱发科 | 真空冻结干燥方法、用于真空冻结干燥装置的喷射喷嘴以及真空冻结干燥装置 |
| US11874060B2 (en) | 2020-11-16 | 2024-01-16 | Sublime Stericeuticals Corporation | Continuous throughput lyophilizer-powder filler within a sterile boundary |
| CN116648300A (zh) * | 2020-12-11 | 2023-08-25 | 默沙东有限责任公司 | 用于隔离、加工和包装医药产品的紧凑型密闭系统 |
| JP7085088B1 (ja) | 2021-08-03 | 2022-06-16 | 株式会社エムアイアイ | 凍結乾燥物 |
| CN113701457A (zh) * | 2021-09-18 | 2021-11-26 | 楚天科技股份有限公司 | 一种冻干系统及冻干方法 |
| CN118302155A (zh) | 2021-10-05 | 2024-07-05 | 赛诺菲 | 用于冷冻和冷冻干燥脂质纳米颗粒（lnp）的方法及其获得的lnp |
| US12085337B2 (en) * | 2021-10-20 | 2024-09-10 | DSM Sales & Manufacturing, Inc. | Freeze-drying systems and methods |
| CN114192067A (zh) * | 2021-12-08 | 2022-03-18 | 南通东概念新材料有限公司 | 一种喷雾干燥、液氮速冻、真空冷冻干燥制备颗粒的方法 |
| US12454789B2 (en) | 2022-03-16 | 2025-10-28 | Haier Us Appliance Solutions, Inc. | Dryer appliance and method for cleaning operation |
| TW202417038A (zh) | 2022-06-15 | 2024-05-01 | 法商賽諾菲公司 | 高度濃縮的抗體組成物 |
| US11998861B2 (en) | 2022-09-15 | 2024-06-04 | Velico Medical, Inc. | Usability of a disposable for a spray drying plasma system |
| US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
| US12083447B2 (en) | 2022-09-15 | 2024-09-10 | Velico Medical, Inc. | Alignment of a disposable for a spray drying plasma system |
| US12246093B2 (en) | 2022-09-15 | 2025-03-11 | Velico Medical, Inc. | Methods for making spray dried plasma |
| US11975274B2 (en) | 2022-09-15 | 2024-05-07 | Velico Medical, Inc. | Blood plasma product |
| WO2024059770A1 (en) | 2022-09-15 | 2024-03-21 | Velico Medical, Inc. | Rapid spray drying system |
| US12246266B2 (en) | 2022-09-15 | 2025-03-11 | Velico Medical, Inc. | Disposable for a spray drying system |
| WO2024184725A1 (en) * | 2023-03-03 | 2024-09-12 | Pfizer Inc. | Systems and methods for reducing electrostatic force in dynamic freeze drying |
| WO2024184721A1 (en) * | 2023-03-03 | 2024-09-12 | Pfizer Inc. | Systems and methods for pre-conditioning frozen bulk in dynamic bulk freeze drying |
| GB202402626D0 (en) * | 2024-02-23 | 2024-04-10 | Ttp Plc | Spray freeze drying formation of dry powder compositions |
| CN120926693B (zh) * | 2025-10-11 | 2026-01-02 | 天津凯莱英医药科技发展有限公司 | 喷雾冷冻干燥系统 |
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| FR1378749A (fr) | 1964-01-07 | 1964-11-13 | Leybold Hochvakuum Anlagen | Procédé et dispositif de séchage par congélation |
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| US3601901A (en) | 1969-09-12 | 1971-08-31 | Earl L Rader | Freeze drying apparatus with removable conveyor and heater structures |
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| US4033048A (en) | 1976-01-12 | 1977-07-05 | Clayton Van Ike | Freeze drying apparatus |
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| JP3686594B2 (ja) | 2001-06-14 | 2005-08-24 | 共和真空技術株式会社 | 食品・薬品類の凍結乾燥装置における液材料の分注装置 |
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| JP3942093B2 (ja) | 2003-01-28 | 2007-07-11 | 株式会社アルバック | 噴霧式真空凍結乾燥装置 |
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| DE102004005660A1 (de) | 2004-02-04 | 2005-08-25 | Rheinische Friedrich-Wilhelms-Universität Bonn | Verfahren und Vorrichtung zur Herstellung eines lyophilisierten pharmazeutischen Materials |
| SE526792C2 (sv) * | 2004-03-03 | 2005-11-08 | Tetra Laval Holdings & Finance | Anordning för evaporativ kylning av en vätskeformig produkt |
| KR20070047239A (ko) | 2004-05-01 | 2007-05-04 | 애그리서치 리미티드 | 건조 방법 및 장치 |
| WO2006008006A1 (en) | 2004-07-23 | 2006-01-26 | Bayer Technology Services Gmbh | Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals) |
| US20060165717A1 (en) | 2005-01-25 | 2006-07-27 | Sanofi Pasteur | DCchol in newborns |
| AR054822A1 (es) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | Emulsion inmuno adyuvante |
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| MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
| DE202006018276U1 (de) | 2006-12-01 | 2007-02-08 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrockungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut |
| DE102007055488B4 (de) * | 2006-12-01 | 2015-01-22 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrocknungsanlage zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut |
| CN101234257B (zh) | 2007-02-01 | 2011-07-27 | 发泰（天津）科技有限公司 | 微波旋转薄膜浓缩器 |
| DE102007012795B3 (de) * | 2007-03-16 | 2008-04-10 | Püschner GmbH + Co. KG | Mikrowellen-Vakuumtrocknungsanlagen und Verfahren zur Trocknung von stückigem, pulverförmigem oder granulatförmigem Gut mittels Mikrowellen |
| EP2101131A1 (en) * | 2007-12-31 | 2009-09-16 | Terruzzi Fercalx S.p.A. | Lyophilization method and system therefor |
| ES2615390T3 (es) | 2008-03-05 | 2017-06-06 | Sanofi Pasteur | Proceso para estabilizar una composición de vacuna que contiene adyuvante |
| EP2578974A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Process line for the production of freeze-dried particles |
| EP2578975A1 (en) | 2011-10-05 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum freeze-dryer |
| UA111631C2 (uk) | 2011-10-06 | 2016-05-25 | Санофі Пастер Са | Нагрівальний пристрій для роторної барабанної ліофільної сушарки |
| EP2578976A1 (en) | 2011-10-06 | 2013-04-10 | Sanofi Pasteur Sa | Rotary drum for use in a vacuum freeze-dryer |
-
2011
- 2011-10-05 EP EP11008057.9A patent/EP2578974A1/en not_active Withdrawn
-
2012
- 2012-04-10 UA UAA201404683A patent/UA111858C2/uk unknown
- 2012-04-10 UA UAA201404685A patent/UA111859C2/uk unknown
- 2012-10-04 WO PCT/EP2012/004168 patent/WO2013050162A1/en not_active Ceased
- 2012-10-04 PE PE2014000479A patent/PE20141979A1/es not_active Application Discontinuation
- 2012-10-04 AU AU2012320854A patent/AU2012320854B2/en active Active
- 2012-10-04 MY MYPI2014000743 patent/MY151369A/en unknown
- 2012-10-04 AU AU2012320848A patent/AU2012320848B8/en not_active Ceased
- 2012-10-04 CN CN201280049534.2A patent/CN103917842B/zh active Active
- 2012-10-04 ES ES12769026.1T patent/ES2608478T3/es active Active
- 2012-10-04 HU HUE12769026A patent/HUE029973T2/en unknown
- 2012-10-04 WO PCT/EP2012/004162 patent/WO2013050156A1/en not_active Ceased
- 2012-10-04 PL PL12769021T patent/PL2764309T3/pl unknown
- 2012-10-04 JP JP2014533796A patent/JP5728135B2/ja active Active
- 2012-10-04 EA EA201490719A patent/EA027630B1/ru not_active IP Right Cessation
- 2012-10-04 CA CA2849802A patent/CA2849802C/en not_active Expired - Fee Related
- 2012-10-04 PE PE2014000480A patent/PE20142141A1/es not_active Application Discontinuation
- 2012-10-04 HU HUE12769021A patent/HUE030970T2/en unknown
- 2012-10-04 DK DK12769021.2T patent/DK2764309T3/en active
- 2012-10-04 PH PH1/2014/500617A patent/PH12014500617A1/en unknown
- 2012-10-04 BR BR112014007862-9A patent/BR112014007862B1/pt active IP Right Grant
- 2012-10-04 US US14/348,877 patent/US9920989B2/en active Active
- 2012-10-04 KR KR1020147011244A patent/KR101512608B1/ko active Active
- 2012-10-04 IN IN2407CHN2014 patent/IN2014CN02407A/en unknown
- 2012-10-04 SG SG11201400641QA patent/SG11201400641QA/en unknown
- 2012-10-04 EP EP12769021.2A patent/EP2764309B1/en active Active
- 2012-10-04 CA CA2849799A patent/CA2849799C/en not_active Expired - Fee Related
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