PE20010711A1 - Genes para enzimas resistentes al calor de la via biosintetica del aminoacido, derivadas de bacterias corineformes termofilas - Google Patents

Genes para enzimas resistentes al calor de la via biosintetica del aminoacido, derivadas de bacterias corineformes termofilas

Info

Publication number
PE20010711A1
PE20010711A1 PE2000001049A PE0010492000A PE20010711A1 PE 20010711 A1 PE20010711 A1 PE 20010711A1 PE 2000001049 A PE2000001049 A PE 2000001049A PE 0010492000 A PE0010492000 A PE 0010492000A PE 20010711 A1 PE20010711 A1 PE 20010711A1
Authority
PE
Peru
Prior art keywords
amino acid
biosynthetic pathway
derived
acid biosynthetic
thermophile
Prior art date
Application number
PE2000001049A
Other languages
English (en)
Inventor
Naoki Akiyoshi
Seiko Hirano
Yoshio Kawahara
Eiichiro Kimura
Osamu Kurahashi
Shinichi Sugimoto
Yumi Matsuzaki
Tsuyoshi Nakamatsu
Kanae Nakamura
Gen Nonaka
Tsuyoshi Osumi
Kazuhiko Matsui
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20010711A1 publication Critical patent/PE20010711A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/01—Oxidoreductases acting on sulfur groups as donors (1.8) with NAD+ or NADP+ as acceptor (1.8.1)
    • C12Y108/01004—Dihydrolipoyl dehydrogenase (1.8.1.4), i.e. lipoamide-dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01041—Isocitrate dehydrogenase (NAD+) (1.1.1.41)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01051—Pyruvate dehydrogenase (NADP+) (1.2.1.51)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04002—Oxoglutarate dehydrogenase (succinyl-transferring) (1.2.4.2), i.e. alpha-ketoglutarat dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
    • C12Y104/01004—Glutamate dehydrogenase (NADP+) (1.4.1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03001—Citrate (Si)-synthase (2.3.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01011—6-Phosphofructokinase (2.7.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01026—Beta-fructofuranosidase (3.2.1.26), i.e. invertase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01031—Phosphoenolpyruvate carboxylase (4.1.1.31)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/03—Oxo-acid-lyases (4.1.3)
    • C12Y401/03001—Isocitrate lyase (4.1.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01003—Aconitate hydratase (4.2.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

SE REFIERE A UNA PROTEINA CUYA SECUENCIA DE AMINOACIDOS 2, 4, 6, 8, 10, 94, 17-20, 22, 24, 26, 28, 30, 27, 34, 80 O DICHAS SECUENCIAS INCLUYENDO SUSTITUCION, EXCLUSION, INSERCION, ADICION, INVERSION DE UNO O VARIOS AMINOACIDOS QUE TIENEN ACTIVIDAD DE ISOCITRATO LIASA Y PRESENTA 30% DE ACTIVIDAD RESIDUAL DESPUES DEL TRATAMIENTO POR CALOR A 50°C DURANTE 5 MINUTOS; ACIL COA CARBOXILASA Y SU PROVENIENTE DE CORYNEBACTERIUM THERMOAMINOGENES, O LA CUAL TIENE ACTIVIDAD DTSR, PRESENTA ACTIVIDAD FOSFOFRUCTOQUINASA A 60°C COMPARADA CON LA ACTIVIDAD A 30°C, IMPARTIR LA CAPACIDAD DE ASIMILAR SUCROSA A LA C. THERMOAMINOGENES, TIENE UNA FUNCION INVOLUCRADA EN LA ABSORCION DE ACIDO GLUTAMICO, PIRUVATO DESHIDROGENASA, PIRUVATO CARBOXILASA, FOSFOENOLPIRUVATO CARBOXILASA Y PRESENTA MENOS DE 50% O MAS DE ACTIVIDAD RESIDUAL DESPUES DE UN TRATAMIENTO POR CALOR A 45°C DURANTE 5 MINUTOS; ACONITASA, ISOCITRATO DESHIDROGENASA, DIHIDROLIPOAMIDA, 2-OXOGLUTARATO DESHIDROGENASA, GLUTAMATO DESHIDROGENASA, CITRATO DE SINTASA. TAMBIEN SE REFIERE A UNA MOLECULA DE ADN QUE CODIFICA LAS PROTEINAS; A UN METODO PARA PRODUCIR L-AMINOACIDO QUE COMPRENDE CULTIVAR UN MICROORGANISMO AL QUE SE LE HA INTRODUCIDO ADN
PE2000001049A 1999-10-04 2000-10-04 Genes para enzimas resistentes al calor de la via biosintetica del aminoacido, derivadas de bacterias corineformes termofilas PE20010711A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28271699 1999-10-04
JP31114799 1999-11-01
JP2000120687 2000-04-21

Publications (1)

Publication Number Publication Date
PE20010711A1 true PE20010711A1 (es) 2001-07-09

Family

ID=27336960

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001049A PE20010711A1 (es) 1999-10-04 2000-10-04 Genes para enzimas resistentes al calor de la via biosintetica del aminoacido, derivadas de bacterias corineformes termofilas

Country Status (12)

Country Link
US (3) US6995250B1 (es)
EP (3) EP1219712B1 (es)
JP (1) JP4337298B2 (es)
KR (1) KR20020042703A (es)
CN (3) CN101096662A (es)
AT (3) ATE450612T1 (es)
AU (1) AU781863B2 (es)
BR (1) BR0014496A (es)
DE (3) DE60043465D1 (es)
PE (1) PE20010711A1 (es)
TW (3) TW200734459A (es)
WO (1) WO2001025447A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
JP4427878B2 (ja) 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
EP1106622A3 (de) * 1999-11-23 2004-01-02 Degussa AG Neue für das pfkA-Gen codierende Nukleotidsequenzen
DE10011922A1 (de) 1999-11-23 2001-05-31 Degussa Neue für das pfkA-Gen codierende Nukleotidsequenzen
PT1325135E (pt) * 2000-10-13 2005-03-31 Archer Daniels Midland Co Gene da carboxilase do piruvato de corynebacterium resistente a retroacao
JP4599726B2 (ja) 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
BR0304860A (pt) * 2002-11-11 2004-08-31 Ajinomoto Kk Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
US7205132B2 (en) * 2004-09-10 2007-04-17 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US9725701B2 (en) 2013-03-15 2017-08-08 Iowa Corn Promotion Board Prokarytoic-type isocitrate dehydrogenase and its application for improving nitrogen utilization in transgenic plants
KR101776375B1 (ko) * 2015-03-18 2017-09-08 씨제이제일제당 (주) 피루브산 디하이드로게나아제 변이체, 이를 포함하는 미생물 및 이를 이용한 l-아미노산 생산 방법
CN106544298B (zh) * 2016-10-27 2020-03-24 广东省微生物研究所 一种芽胞杆菌感受态细胞的制备方法
CN118063566A (zh) * 2022-11-22 2024-05-24 华东理工大学 一种磷酸烯醇式丙酮酸光学探针及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696561B1 (en) * 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
FR2575492B1 (fr) 1984-12-27 1988-09-16 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour la glutamate deshydrogenase, adn recombinant le contenant, et microorganisme contenant l'adn recombinant
JPH07121228B2 (ja) 1986-11-07 1995-12-25 協和醗酵工業株式会社 Ｌ−グルタミン酸およびｌ−プロリンの製造法
JP2520895B2 (ja) 1987-03-04 1996-07-31 旭化成工業株式会社 Ｌ―グルタミン酸の製造方法
US5250434A (en) * 1987-03-27 1993-10-05 Ajinomoto Co., Inc. Microorganisms for production of glutamic acid
GB2223754B (en) 1988-09-12 1992-07-22 Degussa Dna encoding phosphoenolpyruvate carboxylase
JP2990735B2 (ja) 1990-04-20 1999-12-13 味の素株式会社 Ｌ―リジンの発酵的製造法
FR2671800B1 (fr) 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
JP3036912B2 (ja) 1991-09-02 2000-04-24 協和醗酵工業株式会社 遺伝子発現調節ｄｎａ
CA2108564A1 (en) 1991-04-16 1992-10-17 Kevin A. Ward Gene expression cassette containing non-coding sequence of growth hormone gene
EP0551506A1 (fr) 1991-07-30 1993-07-21 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries
JP3298135B2 (ja) 1992-03-04 2002-07-02 味の素株式会社 コリネホルム細菌由来のシュークラーゼ遺伝子
US5539092A (en) * 1992-10-02 1996-07-23 Arch Development Corporation Cyanobacterial and plant acetyl-CoA carboxylase
JPH0763383A (ja) 1993-08-27 1995-03-07 Toshiba Corp 換気扇
JPH07121227A (ja) 1993-10-20 1995-05-12 Fanuc Ltd 非対称型加減速フィルタ
MY113040A (en) * 1994-02-24 2001-11-30 Ajinomoto Kk Novel gene derived from coryneform bacteria and use thereof
CN1272437C (zh) * 1994-06-14 2006-08-30 味之素株式会社 α－酮戊二酸脱氢酶基因以及赖氨酸的生产方法
JPH0866189A (ja) 1994-08-31 1996-03-12 Mitsubishi Chem Corp 新規ｄｎａ断片
JPH08196280A (ja) 1995-01-30 1996-08-06 Ajinomoto Co Inc コリネホルム細菌由来のシュクラーゼ遺伝子とその利用
CA2218139A1 (en) * 1995-04-14 1996-10-17 Arch Development Corporation Acetyl-coa carboxylase compositions and methods of use
JPH1087A (ja) 1996-06-17 1998-01-06 Ajinomoto Co Inc 発酵法による目的物質の製造法
JP4075087B2 (ja) * 1996-12-05 2008-04-16 味の素株式会社 Ｌ−リジンの製造法
JP3767066B2 (ja) 1997-02-25 2006-04-19 味の素株式会社 新規遺伝子
BRPI9813021B1 (pt) 1997-10-04 2016-04-05 Degussa processo para a preparação microbiana de aminoácidos de l-lisina, l-treonina, l-homosserina e glutamato, vetor, e célula transformada
JPH11196887A (ja) 1998-01-16 1999-07-27 Mitsubishi Chemical Corp ホスホエノールピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
JP7121227B2 (ja) * 2017-06-29 2022-08-18 三菱マテリアル株式会社 熱電変換材料、及び、熱電変換材料の製造方法
JP7063383B2 (ja) * 2018-06-08 2022-05-09 株式会社島津製作所 蛍光ｘ線分析装置および蛍光ｘ線分析方法

Also Published As

Publication number Publication date
WO2001025447A1 (fr) 2001-04-12
CN1391612A (zh) 2003-01-15
EP1712632A3 (en) 2006-10-25
AU7556100A (en) 2001-05-10
BR0014496A (pt) 2002-08-20
US7125977B2 (en) 2006-10-24
KR20020042703A (ko) 2002-06-05
JP4337298B2 (ja) 2009-09-30
EP1712632B1 (en) 2009-12-02
US20050176127A1 (en) 2005-08-11
TW200734459A (en) 2007-09-16
EP1710313B1 (en) 2009-12-02
CN101096661B (zh) 2011-10-19
CN101096661A (zh) 2008-01-02
EP1219712A4 (en) 2004-06-02
ATE450613T1 (de) 2009-12-15
EP1712632A2 (en) 2006-10-18
TWI289604B (en) 2007-11-11
US7183403B2 (en) 2007-02-27
DE60043465D1 (de) 2010-01-14
ATE450612T1 (de) 2009-12-15
ATE396272T1 (de) 2008-06-15
EP1710313A1 (en) 2006-10-11
DE60043464D1 (de) 2010-01-14
AU781863B2 (en) 2005-06-16
DE60038967D1 (en) 2008-07-03
CN1333078C (zh) 2007-08-22
US20050239176A1 (en) 2005-10-27
US6995250B1 (en) 2006-02-07
TW200734460A (en) 2007-09-16
EP1219712B1 (en) 2008-05-21
CN101096662A (zh) 2008-01-02
EP1219712A1 (en) 2002-07-03

Similar Documents

Publication Publication Date Title
PE20010711A1 (es) Genes para enzimas resistentes al calor de la via biosintetica del aminoacido, derivadas de bacterias corineformes termofilas
RU2006132818A (ru) Мутантная ацетолактатсинтаза и способ продукции разветвленных l-аминокислот
RU2001130146A (ru) Бактерия, продуцирующая l-аминокислоту, и способ получения l-аминокислоты
ATE422548T1 (de) L-lysin produzierende coryneforme bakterien und verfahren zur herstellung von l-lysin
MXPA00008459A (es) Nuevas secuencias nucleotidicas codificadoras de gen thre y procedimiento para la preparacion por fermentacion de l-treonina utilizando bacterias corineformes.
IL175142A0 (en) High efficiency gene transfer and expresssion in mammalian cells by a multiple transfection procedure of mar sequences
RU2000117837A (ru) Продуцирующие l-лизин коринебактерии и способ получения l-лизина
RU2000123636A (ru) Новые кодирующие нуклеотидные последовательности гена pg1
US20100151449A1 (en) Method for poduction of l-amino acids by fermentation
CN102191247A (zh) 增强的启动子以及使用该启动子产生l-赖氨酸的方法
ES2218009T3 (es) Procedimiento para la preparacion fermentativa de l-aminoacidos utilizando bacterias corineformes.
DE50010097D1 (de) Für das zwa1-Gen codierende Nukleotidsequenzen
RU2692645C2 (ru) Микроорганизм рода Escherichia, продуцирующий L-триптофан, и способ получения L-триптофана с его использованием
EP3498854B1 (en) Method for the fermentative production of l-lysine
EP1491634A1 (en) Feedback resistant acetohydroxy acid synthetase mutants
RU2000125061A (ru) Новые кодирующие нуклеотидные последовательности гена eno
ZA200102385B (en) Nucleotide sequences coding for the dapC gene and process for the production of L-lysine.
MY114645A (en) Cytochrome bd type quinol oxidase gene of brevibacterium lactofermentum
DE60032328D1 (de) Verfahren zur herstellung von coenzym q 10
US20090181435A1 (en) Method for Determining L-Serine, Gene Sequene, Vectors and Micro-Organisms
RU2000130035A (ru) Новые кодирующие нуклеотидные последовательности гена gpm
RU2001108877A (ru) Новые кодирующие нуклеотидные последовательности гена rp1k
RU2000113101A (ru) Способ ферментативного получения l-аминокислот с использованием коринебактерий
RU2000129169A (ru) Новые кодирующие нуклеотидные последовательности гена pfk
RU2000123215A (ru) Новые кодирующие нуклеотидные последовательности гена dapf

Legal Events

Date Code Title Description
FG Grant, registration
FC Refusal