OA13113A - Pyrimidin-4-One Derivatives and their use as P38 Kinase Modulators. - Google Patents

Pyrimidin-4-One Derivatives and their use as P38 Kinase Modulators. Download PDF

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Publication number
OA13113A
OA13113A OA1200500271A OA1200500271A OA13113A OA 13113 A OA13113 A OA 13113A OA 1200500271 A OA1200500271 A OA 1200500271A OA 1200500271 A OA1200500271 A OA 1200500271A OA 13113 A OA13113 A OA 13113A
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OA
OAPI
Prior art keywords
alkyl
alkoxy
independently
halogen
nr6r7
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OA1200500271A
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English (en)
Inventor
Balekudru Devadas
Richard Durley
Brian Hickory
Heather Madsen
Katherine Palmquist
Shaun Selness
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Pharmacia Corp
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Publication of OA13113A publication Critical patent/OA13113A/en

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Engineering & Computer Science (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
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  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
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OA1200500271A 2003-04-03 2004-03-29 Pyrimidin-4-One Derivatives and their use as P38 Kinase Modulators. OA13113A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46012403P 2003-04-03 2003-04-03

Publications (1)

Publication Number Publication Date
OA13113A true OA13113A (en) 2006-11-10

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ID=33131912

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OA1200500271A OA13113A (en) 2003-04-03 2004-03-29 Pyrimidin-4-One Derivatives and their use as P38 Kinase Modulators.

Country Status (24)

Country Link
US (1) US7183287B2 (pt)
EP (1) EP1753731A2 (pt)
JP (1) JP3981398B1 (pt)
KR (1) KR100776120B1 (pt)
CN (1) CN1968937A (pt)
AP (1) AP2005003403A0 (pt)
AU (1) AU2004226165C1 (pt)
BR (1) BRPI0408990A (pt)
CA (1) CA2521081C (pt)
CR (1) CR8007A (pt)
EA (1) EA009743B1 (pt)
EC (1) ECSP056072A (pt)
GE (1) GEP20074255B (pt)
IS (1) IS8006A (pt)
MA (1) MA27754A1 (pt)
MX (1) MXPA05010621A (pt)
NO (1) NO20055092L (pt)
NZ (1) NZ542139A (pt)
OA (1) OA13113A (pt)
RS (1) RS20050732A (pt)
TN (1) TNSN05250A1 (pt)
UA (1) UA81658C2 (pt)
WO (1) WO2004087677A2 (pt)
ZA (1) ZA200506976B (pt)

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HUE041300T2 (hu) 2006-06-26 2019-05-28 Akebia Therapeutics Inc Prolilhidroxiláz inhibitorok és alkalmazási eljárások
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