OA10920A - Carboline derivatives - Google Patents

Carboline derivatives Download PDF

Info

Publication number
OA10920A
OA10920A OA9800218A OA9800218A OA10920A OA 10920 A OA10920 A OA 10920A OA 9800218 A OA9800218 A OA 9800218A OA 9800218 A OA9800218 A OA 9800218A OA 10920 A OA10920 A OA 10920A
Authority
OA
OAPI
Prior art keywords
carbolin
propene
tetrahydro
methylenedioxyphenyl
phenyl
Prior art date
Application number
OA9800218A
Other languages
English (en)
Inventor
Agnes Bombrun
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9609820.7A external-priority patent/GB9609820D0/en
Priority claimed from GBGB9609777.9A external-priority patent/GB9609777D0/en
Application filed by Icos Corp filed Critical Icos Corp
Publication of OA10920A publication Critical patent/OA10920A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA9800218A 1996-05-10 1998-11-09 Carboline derivatives OA10920A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9609820.7A GB9609820D0 (en) 1996-05-10 1996-05-10 Chemical compounds
GBGB9609777.9A GB9609777D0 (en) 1996-05-10 1996-05-10 Chemical compounds

Publications (1)

Publication Number Publication Date
OA10920A true OA10920A (en) 2003-02-21

Family

ID=26309303

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800218A OA10920A (en) 1996-05-10 1998-11-09 Carboline derivatives

Country Status (26)

Country Link
US (2) US6117881A (ko)
EP (1) EP0912567B1 (ko)
JP (1) JP3418405B2 (ko)
KR (1) KR20000010918A (ko)
CN (1) CN1067071C (ko)
AP (1) AP9801365A0 (ko)
AT (1) ATE215950T1 (ko)
AU (1) AU711885B2 (ko)
BG (1) BG102879A (ko)
BR (1) BR9709230A (ko)
CA (1) CA2253948C (ko)
CZ (1) CZ358598A3 (ko)
DE (1) DE69711882T2 (ko)
EA (1) EA199800907A1 (ko)
EE (1) EE9800390A (ko)
ES (1) ES2175404T3 (ko)
HU (1) HUP9901478A3 (ko)
IL (1) IL126951A0 (ko)
IS (1) IS4864A (ko)
NO (1) NO985222L (ko)
OA (1) OA10920A (ko)
PL (1) PL329875A1 (ko)
SK (1) SK154498A3 (ko)
TR (1) TR199802282T2 (ko)
WO (1) WO1997043287A1 (ko)
YU (1) YU49898A (ko)

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WO2000015639A1 (en) * 1998-09-16 2000-03-23 Icos Corporation Carboline derivatives as cgmp phosphodiesterase inhibitors
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US6451807B1 (en) 1999-04-30 2002-09-17 Lilly Icos, Llc. Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor
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WO2002098875A1 (en) * 2001-06-05 2002-12-12 Lilly Icos Llc Carboline derivatives as pde-5 inhibitors
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US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
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CA2529307C (en) 2003-06-13 2013-12-24 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
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US8506934B2 (en) 2005-04-29 2013-08-13 Robert I. Henkin Methods for detection of biological substances
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CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
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US20090270623A1 (en) * 2005-11-18 2009-10-29 Naoyuki Shimomura Process for production of cinnamide derivative
WO2007058304A1 (ja) * 2005-11-18 2007-05-24 Eisai R & D Management Co., Ltd. シンナミド化合物の塩またはそれらの溶媒和物
CA2629745A1 (en) 2005-11-24 2007-05-31 Eisai R & D Management Co., Ltd. Morpholine type cinnamide compound
US20070117839A1 (en) * 2005-11-24 2007-05-24 Eisai R&D Management Co., Ltd. Two cyclic cinnamide compound
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EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
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EP3108245B1 (en) 2014-02-18 2020-07-22 Robert I. Henkin Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
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Also Published As

Publication number Publication date
EP0912567A1 (en) 1999-05-06
HUP9901478A2 (hu) 1999-08-30
DE69711882T2 (de) 2002-10-31
ES2175404T3 (es) 2002-11-16
YU49898A (sh) 2000-03-21
BR9709230A (pt) 1999-08-10
AP9801365A0 (en) 1998-12-31
NO985222L (no) 1999-01-11
US6306870B1 (en) 2001-10-23
HUP9901478A3 (en) 1999-11-29
TR199802282T2 (xx) 1999-03-22
US6117881A (en) 2000-09-12
CZ358598A3 (cs) 1999-03-17
NO985222D0 (no) 1998-11-09
PL329875A1 (en) 1999-04-12
DE69711882D1 (en) 2002-05-16
EE9800390A (et) 1999-06-15
CN1218471A (zh) 1999-06-02
IL126951A0 (en) 1999-09-22
IS4864A (is) 1998-10-13
BG102879A (en) 1999-09-30
AU2891097A (en) 1997-12-05
CN1067071C (zh) 2001-06-13
JP2000513717A (ja) 2000-10-17
JP3418405B2 (ja) 2003-06-23
CA2253948A1 (en) 1997-11-20
AU711885B2 (en) 1999-10-21
ATE215950T1 (de) 2002-04-15
SK154498A3 (en) 2000-01-18
KR20000010918A (ko) 2000-02-25
EP0912567B1 (en) 2002-04-10
CA2253948C (en) 2005-07-26
WO1997043287A1 (en) 1997-11-20
EA199800907A1 (ru) 1999-04-29

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