OA10500A - Valaciclovir tablets containing colloidal silicon dioxide - Google Patents

Valaciclovir tablets containing colloidal silicon dioxide Download PDF

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Publication number
OA10500A
OA10500A OA70052A OA70052A OA10500A OA 10500 A OA10500 A OA 10500A OA 70052 A OA70052 A OA 70052A OA 70052 A OA70052 A OA 70052A OA 10500 A OA10500 A OA 10500A
Authority
OA
OAPI
Prior art keywords
tablet
valaciclovir
présent
filler
lubricant
Prior art date
Application number
OA70052A
Other languages
English (en)
Inventor
Barry Howard Carter
Lioyd Gary Tillman
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10768317&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA10500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of OA10500A publication Critical patent/OA10500A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA70052A 1995-01-20 1997-07-16 Valaciclovir tablets containing colloidal silicon dioxide OA10500A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9501127.6A GB9501127D0 (en) 1995-01-20 1995-01-20 Tablet

Publications (1)

Publication Number Publication Date
OA10500A true OA10500A (en) 2002-04-10

Family

ID=10768317

Family Applications (1)

Application Number Title Priority Date Filing Date
OA70052A OA10500A (en) 1995-01-20 1997-07-16 Valaciclovir tablets containing colloidal silicon dioxide

Country Status (39)

Country Link
US (1) US5879706A (pt)
EP (1) EP0806943B1 (pt)
JP (1) JP3350055B2 (pt)
KR (1) KR100412298B1 (pt)
CN (2) CN1131026C (pt)
AP (1) AP666A (pt)
AT (1) ATE190483T1 (pt)
AU (1) AU710823B2 (pt)
BG (1) BG63187B1 (pt)
BR (1) BR9606769A (pt)
CA (1) CA2210891C (pt)
CY (1) CY2182B1 (pt)
CZ (1) CZ296514B6 (pt)
DE (1) DE69607146T2 (pt)
DK (1) DK0806943T3 (pt)
EA (1) EA000276B1 (pt)
EE (1) EE03336B1 (pt)
ES (1) ES2145425T3 (pt)
FI (1) FI119722B (pt)
GB (1) GB9501127D0 (pt)
GE (1) GEP20022752B (pt)
GR (1) GR3033677T3 (pt)
HK (1) HK1002851A1 (pt)
HU (1) HU226131B1 (pt)
IL (1) IL116830A (pt)
IN (1) IN181318B (pt)
MY (1) MY126346A (pt)
NO (1) NO311488B1 (pt)
NZ (1) NZ298846A (pt)
OA (1) OA10500A (pt)
PL (1) PL185307B1 (pt)
PT (1) PT806943E (pt)
RO (1) RO118175B1 (pt)
SK (1) SK282030B6 (pt)
TR (1) TR199700657T1 (pt)
UA (1) UA68325C2 (pt)
UY (2) UY25774A1 (pt)
WO (1) WO1996022082A1 (pt)
ZA (1) ZA96448B (pt)

Families Citing this family (44)

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GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
AU722304B2 (en) * 1996-01-19 2000-07-27 Glaxo Group Limited Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
AR016827A1 (es) 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
IL143407A0 (en) * 1998-12-18 2002-04-21 Abbott Lab Controlled release formulation of divalproex sodium
GB0010446D0 (en) * 2000-04-28 2000-06-14 Glaxo Wellcome Kk Pharmaceutical formulation
PT1383482E (pt) * 2001-05-01 2007-09-20 Pfizer Prod Inc Método para o fabrico de uma composição farmacêutica de baixa dosagem tendo distribuição e potência de fármaco uniforme
US7815936B2 (en) * 2001-10-30 2010-10-19 Evonik Degussa Gmbh Use of granular materials based on pyrogenically produced silicon dioxide in pharmaceutical compositions
JP2005511612A (ja) * 2001-11-05 2005-04-28 グラクソ　グループ　リミテッド 塩酸バラシクロビルの無水結晶形
KR20070020149A (ko) * 2001-11-14 2007-02-16 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르의 합성 및 정제 방법
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
AU2003240213A1 (en) * 2002-06-24 2004-01-06 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050051922A1 (en) * 2002-09-20 2005-03-10 Avinash Nangia Pharmaceutical composition with sodium lauryl sulfate as an extra-granular absorption/compression enhancer and the process to make the same
US20050059684A1 (en) * 2002-10-16 2005-03-17 Ben-Zion Dolitzky Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
EP1551838B1 (en) * 2002-10-16 2006-08-09 Teva Pharmaceutical Industries Ltd. Method for reducing residual alcohols in crystalline valacyclovir hydrochloride
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
WO2004106338A1 (en) * 2003-05-30 2004-12-09 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Novel crystalline forms of valacyclovir hydrochloride
TW200510414A (en) * 2003-06-02 2005-03-16 Teva Pharma Novel crystalline forms of valacyclovir hydrochloride
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
TR201910447T4 (tr) 2003-09-12 2019-08-21 Amgen Inc Sinakalset HCI'nin hızlı çözünme formülasyonu.
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
EP1541133B1 (en) * 2003-12-09 2005-08-10 Helm AG Pharmaceutical formulation of valaciclovir
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
KR101116747B1 (ko) 2004-12-06 2012-02-22 에스케이케미칼주식회사 안정성이 개선된 말레인산 암로디핀 약제 조성물
DE602006017188D1 (de) 2005-03-07 2010-11-11 Bayer Schering Pharma Ag Pharmazeutische zusammensetzung mit einem omega-carboxyaryl-substituierten diphenylharnstoff zur behandlung von krebs
WO2006127217A2 (en) * 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir
EP1746098A1 (en) * 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
WO2007090595A1 (en) * 2006-02-06 2007-08-16 Fidia Pharmaceutici S.P.A. Solid formulations of valacyclovir hydrochloride
JP2009536165A (ja) * 2006-05-10 2009-10-08 エボニック デグサ ゲーエムベーハー 医薬組成物におけるロール圧縮された熱分解的に製造された二酸化ケイ素の使用
PT2037887E (pt) * 2006-05-31 2010-12-07 Vertex Pharma Formulações orais de libertação controlada de um inibidor da enzima conversora de interleucina-1 beta
WO2008006534A2 (en) * 2006-07-11 2008-01-17 Lek Pharmaceuticals D.D. Multiple unit tablets
US20080167325A1 (en) * 2006-12-27 2008-07-10 Bs Praveen Kumar Valacyclovir compositions
US20090076039A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched valacyclovir
ITRM20080027A1 (it) * 2008-01-18 2009-07-19 Maria Balestrieri Uso di aciclovir per il trattamento delle condilomatosi.
US20100124560A1 (en) * 2008-11-14 2010-05-20 Mcneil Ab Multi portion intra-oral dosage form and use thereof
US8513261B2 (en) * 2009-03-13 2013-08-20 Toyama Chemical Co., Ltd. Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
CH703348A1 (de) * 2010-06-29 2011-12-30 Mepha Gmbh Zusammensetzungen mit hohem Wirkstoffanteil an pharmazeutisch aktiven Substanzen.
GB2515486A (en) * 2013-06-24 2014-12-31 Kraft Foods R & D Inc Soluble Beverage Ingredients
KR101497508B1 (ko) * 2013-12-20 2015-03-03 한국유나이티드제약 주식회사 펠라고니움 시도이데스 추출물 및 규산 화합물을 포함하는 고형 제제 및 이의 제조 방법
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
WO2020049536A1 (en) * 2018-09-07 2020-03-12 Jubilant Generics Limited Pharmaceutical compositions of valacyclovir or its pharmaceutically acceptable salts thereof
CN110279667B (zh) * 2019-07-30 2023-02-10 珠海润都制药股份有限公司 一种盐酸伐昔洛韦片及其制备方法
TW202231270A (zh) * 2020-12-01 2022-08-16 南韓商Ｌｇ化學股份有限公司 用於口服投予的包含１－（３－氰基－１－異丙基－吲哚－５－基）吡唑－４－羧酸之複合調製劑和製備彼之方法

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
CA1259924A (en) * 1985-03-25 1989-09-26 Wallace E. Becker Pharmaceutical tableting method
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
ATE82680T1 (de) * 1988-05-04 1992-12-15 Smith Kline French Lab Kautablette.
IL100796A (en) * 1991-01-30 1998-09-24 Wellcome Found Water-dispersed tablets containing acyclovir or lemotrigin
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet

Also Published As

Publication number Publication date
IL116830A (en) 2000-02-29
BR9606769A (pt) 1997-12-30
FI973062A0 (fi) 1997-07-18
CN1313081C (zh) 2007-05-02
GB9501127D0 (en) 1995-03-08
ES2145425T3 (es) 2000-07-01
ATE190483T1 (de) 2000-04-15
WO1996022082A1 (en) 1996-07-25
JPH10512564A (ja) 1998-12-02
HU226131B1 (en) 2008-05-28
CN1494898A (zh) 2004-05-12
US5879706A (en) 1999-03-09
CA2210891A1 (en) 1996-07-25
CN1131026C (zh) 2003-12-17
DE69607146T2 (de) 2000-09-21
EA000276B1 (ru) 1999-02-25
MX9705459A (es) 1997-10-31
KR19980701524A (ko) 1998-05-15
RO118175B1 (ro) 2003-03-28
BG63187B1 (bg) 2001-06-29
JP3350055B2 (ja) 2002-11-25
AP9701057A0 (en) 1997-10-31
CA2210891C (en) 2009-05-19
HUP9801872A3 (en) 2001-02-28
HUP9801872A2 (hu) 1999-10-28
CZ296514B6 (cs) 2006-03-15
TR199700657T1 (xx) 1998-02-21
SK282030B6 (sk) 2001-10-08
UY25778A1 (es) 2000-08-21
UY25774A1 (es) 2000-10-31
DK0806943T3 (da) 2000-07-24
GR3033677T3 (en) 2000-10-31
FI119722B (fi) 2009-02-27
KR100412298B1 (ko) 2004-04-21
EE03336B1 (et) 2001-02-15
SK96497A3 (en) 1998-01-14
IN181318B (pt) 1998-05-09
FI973062A (fi) 1997-09-18
UA68325C2 (en) 2004-08-16
AU710823B2 (en) 1999-09-30
CY2182B1 (en) 2002-08-23
IL116830A0 (en) 1996-05-14
PL185307B1 (pl) 2003-04-30
MY126346A (en) 2006-09-29
PT806943E (pt) 2000-08-31
AU4453496A (en) 1996-08-07
CN1179100A (zh) 1998-04-15
ZA96448B (en) 1996-08-07
DE69607146D1 (de) 2000-04-20
EP0806943B1 (en) 2000-03-15
GEP20022752B (en) 2002-08-26
EP0806943A1 (en) 1997-11-19
CZ229297A3 (cs) 1998-02-18
AP666A (en) 1998-08-24
PL321361A1 (en) 1997-12-08
NO311488B1 (no) 2001-12-03
EA199700123A1 (ru) 1997-12-30
NZ298846A (en) 1998-06-26
NO973327L (no) 1997-09-16
BG101831A (en) 1998-04-30
HK1002851A1 (en) 1998-09-25
NO973327D0 (no) 1997-07-18

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