NZ578503A - Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases - Google Patents

Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases

Info

Publication number
NZ578503A
NZ578503A NZ578503A NZ57850304A NZ578503A NZ 578503 A NZ578503 A NZ 578503A NZ 578503 A NZ578503 A NZ 578503A NZ 57850304 A NZ57850304 A NZ 57850304A NZ 578503 A NZ578503 A NZ 578503A
Authority
NZ
New Zealand
Prior art keywords
compound according
disorders
compound
methyl
compounds
Prior art date
Application number
NZ578503A
Other languages
English (en)
Inventor
Brian Smith
Charles Gilson
Jeffrey Schultz
Jeffrey Smith
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of NZ578503A publication Critical patent/NZ578503A/en

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
NZ578503A 2003-06-17 2004-06-16 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases NZ578503A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47928003P 2003-06-17 2003-06-17

Publications (1)

Publication Number Publication Date
NZ578503A true NZ578503A (en) 2011-02-25

Family

ID=33563791

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ578503A NZ578503A (en) 2003-06-17 2004-06-16 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases

Country Status (14)

Country Link
US (3) US7704993B2 (enExample)
EP (2) EP2332920A3 (enExample)
JP (2) JP4782003B2 (enExample)
KR (1) KR101152521B1 (enExample)
CN (4) CN1805938B (enExample)
AU (1) AU2004253888B2 (enExample)
BR (1) BRPI0411470A (enExample)
CA (2) CA2529320C (enExample)
EA (1) EA016558B1 (enExample)
IL (1) IL172334A (enExample)
MX (1) MXPA05013366A (enExample)
NZ (1) NZ578503A (enExample)
WO (1) WO2005003096A1 (enExample)
ZA (2) ZA200510194B (enExample)

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CN105693610B (zh) * 2014-11-28 2019-01-11 国药集团宜宾制药有限责任公司 氯卡色林中间体的制备方法
MX373319B (es) * 2015-04-27 2020-06-13 Arena Pharm Inc Derivados de hexahidro-[1-4]diazepino[6,7,1-hi]indol-8-carboxamida como agonistas del receptor 5-ht2c y el uso de los mismos en el tratamiento de enfermedades relacionadas con dicho receptor.
JP6789578B2 (ja) 2015-07-31 2020-11-25 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ｈｔ２ｃ受容体アゴニストおよび組成物、ならびに使用方法
CN105777638B (zh) * 2016-01-06 2019-07-30 北京修正创新药物研究院有限公司 氯卡色林杂质的制备方法
CN106631823B (zh) * 2016-12-20 2022-04-26 天津泰普制药有限公司 一种氯卡色林中间体的制备方法
CN107353250B (zh) * 2016-12-27 2019-11-12 开封制药(集团)有限公司 一种氯卡色林的合成方法
WO2019131902A1 (ja) 2017-12-27 2019-07-04 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬
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