ZA200510255B - Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases - Google Patents

Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases

Info

Publication number
ZA200510255B
ZA200510255B ZA200510255A ZA200510255A ZA200510255B ZA 200510255 B ZA200510255 B ZA 200510255B ZA 200510255 A ZA200510255 A ZA 200510255A ZA 200510255 A ZA200510255 A ZA 200510255A ZA 200510255 B ZA200510255 B ZA 200510255B
Authority
ZA
South Africa
Prior art keywords
treatment
associated diseases
derivatives useful
receptor associated
5ht2c receptor
Prior art date
Application number
ZA200510255A
Other languages
English (en)
Inventor
Smith Brian
Schulz Jeffrey
Charles Gilson Iii
Smith Jeffrey
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of ZA200510255B publication Critical patent/ZA200510255B/xx

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
ZA200510255A 2003-06-17 2005-12-15 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases ZA200510255B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47928003P 2003-06-17 2003-06-17

Publications (1)

Publication Number Publication Date
ZA200510255B true ZA200510255B (en) 2006-12-27

Family

ID=33563791

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200510194A ZA200510194B (en) 2003-06-17 2005-12-14 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
ZA200510255A ZA200510255B (en) 2003-06-17 2005-12-15 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200510194A ZA200510194B (en) 2003-06-17 2005-12-14 Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases

Country Status (14)

Country Link
US (3) US7704993B2 (xx)
EP (2) EP2332920A3 (xx)
JP (2) JP4782003B2 (xx)
KR (1) KR101152521B1 (xx)
CN (4) CN101792417A (xx)
AU (1) AU2004253888B2 (xx)
BR (1) BRPI0411470A (xx)
CA (2) CA2888392A1 (xx)
EA (1) EA016558B1 (xx)
IL (1) IL172334A (xx)
MX (1) MXPA05013366A (xx)
NZ (1) NZ578503A (xx)
WO (1) WO2005003096A1 (xx)
ZA (2) ZA200510194B (xx)

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CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
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CN104130188B (zh) * 2014-08-05 2016-08-31 南京工业大学 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备方法
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MA42527A (fr) 2015-07-31 2021-04-07 Arena Pharm Inc Agonistes de récepteur 5-ht2c et compositions et procédés d'utilisation
CN105777638B (zh) * 2016-01-06 2019-07-30 北京修正创新药物研究院有限公司 氯卡色林杂质的制备方法
CN106631823B (zh) * 2016-12-20 2022-04-26 天津泰普制药有限公司 一种氯卡色林中间体的制备方法
CN107353250B (zh) * 2016-12-27 2019-11-12 开封制药(集团)有限公司 一种氯卡色林的合成方法
EP3733204A4 (en) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited THERAPEUTIC FOR EXERCISE INCONTINENCE AND STAIR INCONTINENCE
CN108358796B (zh) * 2018-02-23 2021-03-23 广州同隽医药科技有限公司 一种绿卡色林关键中间体ⅰ的制备方法
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