NZ550534A - Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof - Google Patents

Info

Publication number

NZ550534A

NZ550534A NZ550534A NZ55053405A NZ550534A NZ 550534 A NZ550534 A NZ 550534A NZ 550534 A NZ550534 A NZ 550534A NZ 55053405 A NZ55053405 A NZ 55053405A NZ 550534 A NZ550534 A NZ 550534A

Authority

NZ

New Zealand

Prior art keywords

oct

indazole

azabicyclo

carboxamide

carbon atoms

Prior art date

2004-03-25

Links

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• Global Dossier
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• 238000002360 preparation method Methods 0.000 title claims description 73
• IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title abstract description 7
• 150000002473 indoazoles Chemical class 0.000 title abstract 2
• CSNIZNHTOVFARY-UHFFFAOYSA-N 1,2-benzothiazole Chemical class C1=CC=C2C=NSC2=C1 CSNIZNHTOVFARY-UHFFFAOYSA-N 0.000 title description 6
• 150000008316 benzisoxazoles Chemical class 0.000 title description 3
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• 125000000217 alkyl group Chemical group 0.000 claims description 143
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 108
• 150000003839 salts Chemical class 0.000 claims description 51
• 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 48
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• GTNJYSHYBCIFTF-UHFFFAOYSA-N tert-butyl 5-bromo-1h-indazole-3-carboxylate Chemical compound C1=C(Br)C=C2C(C(=O)OC(C)(C)C)=NNC2=C1 GTNJYSHYBCIFTF-UHFFFAOYSA-N 0.000 description 1
• VSLFHIMHDHPVST-UHFFFAOYSA-N tert-butyl 6-bromo-1h-indazole-3-carboxylate Chemical compound BrC1=CC=C2C(C(=O)OC(C)(C)C)=NNC2=C1 VSLFHIMHDHPVST-UHFFFAOYSA-N 0.000 description 1
• ACNRTYKOPZDRCO-UHFFFAOYSA-N tert-butyl n-(2-oxoethyl)carbamate Chemical compound CC(C)(C)OC(=O)NCC=O ACNRTYKOPZDRCO-UHFFFAOYSA-N 0.000 description 1
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• GZNAASVAJNXPPW-UHFFFAOYSA-M tin(4+) chloride dihydrate Chemical compound O.O.[Cl-].[Sn+4] GZNAASVAJNXPPW-UHFFFAOYSA-M 0.000 description 1
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• DQWPFSLDHJDLRL-UHFFFAOYSA-N triethyl phosphate Chemical compound CCOP(=O)(OCC)OCC DQWPFSLDHJDLRL-UHFFFAOYSA-N 0.000 description 1
• SEDZOYHHAIAQIW-UHFFFAOYSA-N trimethylsilyl azide Chemical compound C[Si](C)(C)N=[N+]=[N-] SEDZOYHHAIAQIW-UHFFFAOYSA-N 0.000 description 1
• COIOYMYWGDAQPM-UHFFFAOYSA-N tris(2-methylphenyl)phosphane Chemical compound CC1=CC=CC=C1P(C=1C(=CC=CC=1)C)C1=CC=CC=C1C COIOYMYWGDAQPM-UHFFFAOYSA-N 0.000 description 1
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