NZ333809A - Parathyroid hormone analogues for use as medicaments in treating osteoporosis - Google Patents

Parathyroid hormone analogues for use as medicaments in treating osteoporosis

Info

Publication number
NZ333809A
NZ333809A NZ333809A NZ33380997A NZ333809A NZ 333809 A NZ333809 A NZ 333809A NZ 333809 A NZ333809 A NZ 333809A NZ 33380997 A NZ33380997 A NZ 33380997A NZ 333809 A NZ333809 A NZ 333809A
Authority
NZ
New Zealand
Prior art keywords
hpth
parathyroid hormone
treating osteoporosis
analogues
medicaments
Prior art date
Application number
NZ333809A
Other languages
English (en)
Inventor
Jean-Rene Barbier
Paul Morley
Witold Neugebauer
Virginia Ross
James Whitfield
Gordon E Willick
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/691,647 external-priority patent/US5955425A/en
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of NZ333809A publication Critical patent/NZ333809A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measurement Of Radiation (AREA)
NZ333809A 1996-08-02 1997-08-01 Parathyroid hormone analogues for use as medicaments in treating osteoporosis NZ333809A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/691,647 US5955425A (en) 1996-08-02 1996-08-02 Parathyroid hormone analogues for the treatment of osteoporosis
US4056097P 1997-03-14 1997-03-14
PCT/CA1997/000547 WO1998005683A1 (en) 1996-08-02 1997-08-01 Parathyroid hormone analogues for the treatment of osteoporosis

Publications (1)

Publication Number Publication Date
NZ333809A true NZ333809A (en) 2000-07-28

Family

ID=26717175

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ333809A NZ333809A (en) 1996-08-02 1997-08-01 Parathyroid hormone analogues for use as medicaments in treating osteoporosis

Country Status (24)

Country Link
EP (1) EP0915911B1 (enExample)
JP (3) JP4122061B2 (enExample)
KR (1) KR100500859B1 (enExample)
CN (1) CN1176947C (enExample)
AT (1) ATE253078T1 (enExample)
AU (1) AU723728B2 (enExample)
BG (1) BG103128A (enExample)
BR (1) BR9711002B1 (enExample)
CA (1) CA2261564C (enExample)
CZ (1) CZ34799A3 (enExample)
DE (1) DE69725850T2 (enExample)
DK (1) DK0915911T3 (enExample)
EE (1) EE9900039A (enExample)
ES (1) ES2207740T3 (enExample)
FI (1) FI990126A7 (enExample)
GE (1) GEP20033095B (enExample)
IS (1) IS4962A (enExample)
LV (1) LV12293B (enExample)
NZ (1) NZ333809A (enExample)
PT (1) PT915911E (enExample)
RU (1) RU2203286C2 (enExample)
SI (1) SI9720057A (enExample)
SK (1) SK287397B6 (enExample)
WO (1) WO1998005683A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1261281A (zh) * 1997-05-14 2000-07-26 罗纳·布朗克罗尔药制品有限公司 肽甲状旁腺激素类似物
JP4486256B2 (ja) 1998-10-22 2010-06-23 ザ・ジェネラル・ホスピタル・コーポレイション 副甲状腺ホルモン(PTH)および副甲状腺ホルモン関連ペプチド(PTHrP)の生物活性ペプチドおよびペプチド誘導体
AU1633200A (en) 1998-11-25 2000-06-13 General Hospital Corporation, The Human parathyroid hormone modifications, preparation and use
WO2000040698A1 (en) 1998-12-31 2000-07-13 The General Hospital Corporation Pth receptor and screening assay utilizing the same
JP2003505514A (ja) * 1999-07-28 2003-02-12 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルベニア 破骨細胞生成を阻害する方法
US6316410B1 (en) * 1999-09-22 2001-11-13 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis
AU2002339843B2 (en) 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
JP4959917B2 (ja) * 2001-08-17 2012-06-27 ノバルティス アーゲー 副甲状腺ホルモンフラグメント用経口送達剤としての5−cnac
MXPA04006728A (es) 2002-01-10 2005-08-19 Osteotrophin Llc Tratamiento de desordenes oseos con medicamentos anabolicos esqueleticos.
EP1567178A4 (en) * 2002-11-01 2009-07-15 Amgen Inc MODULATORS OF RECEPTORS FOR NEUTRAL THERAPY HORMONE AND SIDE-HORSE HORMONE-RELATED PROTEINS
CN100508957C (zh) * 2003-01-21 2009-07-08 尤尼金实验室股份有限公司 肽经口输递的改进
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
WO2007130113A2 (en) * 2005-09-06 2007-11-15 Zelos Therapeutics, Inc. Parathyroid hormone analogues and methods of use
EP2056862A2 (en) * 2006-07-31 2009-05-13 Zelos Therapeutics, Inc. Parathyroid hormone analogues and uses thereof
KR101108354B1 (ko) 2006-10-13 2012-01-25 일라이 릴리 앤드 캄파니 Pth 수용체 조절제로서의 페길화된 pth 및 그의 용도
CA2694667C (en) 2007-08-01 2018-10-30 The General Hospital Corporation Screening methods using g-protein coupled receptors and related compositions
RU2604809C2 (ru) * 2010-05-13 2016-12-10 Дзе Дженерал Хоспитал Корпорейшн Аналоги паратиреоидного гормона и их применение
CN105440126B (zh) * 2015-12-31 2019-10-25 南京工业大学 治疗骨质疏松的α-螺旋多肽及其制备方法与应用
WO2019018238A1 (en) 2017-07-15 2019-01-24 The Regents Of The University Of California CATHEPSIN K OSTEOADSORBENT FLUOROGEN SUBSTRATE FOR THE IMAGING OF OSTEOCLAST ACTIVITY AND MIGRATION
WO2020064190A1 (en) 2018-09-26 2020-04-02 Borealis Ag Propylene copolymer composition with excellent optical and mechanical properties
CN113549144A (zh) * 2021-06-30 2021-10-26 华南理工大学 一种特立帕肽hPTH(1-34)的生产和纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
US5317010A (en) * 1991-10-10 1994-05-31 Peter K. T. Pang Parathyroid hormone analogues substituted at AA 25, 26, 27, and use in osteoporosis treatment
US5814603A (en) * 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) * 1992-07-15 1996-10-17 Novartis Ag Variants of parathyroid hormone and its fragments
US5556940A (en) * 1994-06-20 1996-09-17 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis

Also Published As

Publication number Publication date
CN1231676A (zh) 1999-10-13
JP4122061B2 (ja) 2008-07-23
CA2261564C (en) 2007-10-30
ATE253078T1 (de) 2003-11-15
SK13299A3 (en) 1999-10-08
KR20000029783A (ko) 2000-05-25
JP2007254480A (ja) 2007-10-04
SK287397B6 (sk) 2010-08-09
AU723728B2 (en) 2000-09-07
DE69725850T2 (de) 2004-08-19
SI9720057A (sl) 1999-12-31
FI990126A0 (fi) 1999-01-22
DE69725850D1 (de) 2003-12-04
AU3690597A (en) 1998-02-25
BR9711002A (pt) 2002-01-15
CZ34799A3 (cs) 1999-07-14
GEP20033095B (en) 2003-10-27
KR100500859B1 (ko) 2005-07-14
CA2261564A1 (en) 1998-02-12
CN1176947C (zh) 2004-11-24
DK0915911T3 (da) 2004-03-08
BG103128A (bg) 2000-05-31
EP0915911A1 (en) 1999-05-19
LV12293B (en) 2000-11-20
JP2001500845A (ja) 2001-01-23
FI990126L (fi) 1999-03-31
FI990126A7 (fi) 1999-03-31
JP2009057386A (ja) 2009-03-19
PT915911E (pt) 2004-03-31
RU2203286C2 (ru) 2003-04-27
EE9900039A (et) 1999-08-16
LV12293A (lv) 1999-06-20
IS4962A (is) 1999-01-29
WO1998005683A1 (en) 1998-02-12
BR9711002B1 (pt) 2011-09-06
JP4224111B2 (ja) 2009-02-12
ES2207740T3 (es) 2004-06-01
EP0915911B1 (en) 2003-10-29

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