NZ296648A - Nematode-extracted serine protease inhibitors and anticoagulant proteins - Google Patents

Nematode-extracted serine protease inhibitors and anticoagulant proteins

Info

Publication number
NZ296648A
NZ296648A NZ296648A NZ29664895A NZ296648A NZ 296648 A NZ296648 A NZ 296648A NZ 296648 A NZ296648 A NZ 296648A NZ 29664895 A NZ29664895 A NZ 29664895A NZ 296648 A NZ296648 A NZ 296648A
Authority
NZ
New Zealand
Prior art keywords
seq
amino acid
protein
cys
tyr
Prior art date
Application number
NZ296648A
Other languages
English (en)
Inventor
George Phillip Vlasuk
Patrick Eric Hugo Stanssens
Joris Hilda Lieven Messens
Marc Josef Lauwereys
Yves Rene Laroche
Laurent Stephane Jespers
Yannick Georges Joze Gansemans
Matthew Moyle
Peter W Bergum
Original Assignee
Corvas Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/326,110 external-priority patent/US5945275A/en
Priority claimed from US08/486,397 external-priority patent/US5866542A/en
Priority claimed from US08/486,399 external-priority patent/US5866543A/en
Priority claimed from US08/465,380 external-priority patent/US5863894A/en
Priority claimed from US08/461,965 external-priority patent/US5872098A/en
Application filed by Corvas Int Inc filed Critical Corvas Int Inc
Publication of NZ296648A publication Critical patent/NZ296648A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ296648A 1994-10-18 1995-10-17 Nematode-extracted serine protease inhibitors and anticoagulant proteins NZ296648A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US08/326,110 US5945275A (en) 1994-10-18 1994-10-18 Nematode-extracted anticoagulant protein
US08/486,397 US5866542A (en) 1994-10-18 1995-06-05 Nematode-extracted anticoagulant protein
US08/486,399 US5866543A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US08/465,380 US5863894A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
US08/461,965 US5872098A (en) 1995-06-05 1995-06-05 Nematode-extracted anticoagulant protein
PCT/US1995/013231 WO1996012021A2 (en) 1994-10-18 1995-10-17 Nematode-extracted serine protease inhibitors and anticoagulant proteins

Publications (1)

Publication Number Publication Date
NZ296648A true NZ296648A (en) 2001-05-25

Family

ID=27541063

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ296648A NZ296648A (en) 1994-10-18 1995-10-17 Nematode-extracted serine protease inhibitors and anticoagulant proteins

Country Status (12)

Country Link
US (11) US6090916A (enExample)
EP (2) EP1772516A1 (enExample)
JP (3) JP3811186B2 (enExample)
AT (1) ATE346928T1 (enExample)
AU (1) AU711405B2 (enExample)
DE (1) DE69535317T2 (enExample)
DK (1) DK0788546T3 (enExample)
ES (1) ES2276396T3 (enExample)
HU (1) HU225126B1 (enExample)
NZ (1) NZ296648A (enExample)
PL (1) PL183855B1 (enExample)
WO (1) WO1996012021A2 (enExample)

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US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP1772516A1 (en) * 1994-10-18 2007-04-11 Dendreon Corporation Pharmaceutical compositions for the treatment of thrombosis
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
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WO2000051623A2 (en) 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US7704958B1 (en) 1999-03-05 2010-04-27 Bio Holding, Inc. Methods and compositions for inhibiting apoptosis using serine protease inhibitors
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CN102617722B (zh) * 2007-03-05 2013-10-16 广东医学院 犬钩虫抗凝肽及其制备和应用
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KR101499302B1 (ko) 2009-11-17 2015-03-09 아이덱스 래보러토리즈, 인코포레이티드 회충을 검출하기 위한 방법, 장치, 키트 및 조성물
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EP3122782A4 (en) 2014-03-27 2017-09-13 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
CN116077648A (zh) 2015-12-11 2023-05-09 武田药品工业株式会社 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
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JP2023526880A (ja) * 2020-05-26 2023-06-26 ウニヴェルシテーツメディツィン・デア・ヨハネス・グーテンベルク－ウニヴェルシテート・マインツ コロナウイルス感染症および関連する凝固障害を処置するための方法および組成物
AU2022291028A1 (en) * 2021-06-09 2024-01-18 Universitätsmedizin Der Johannes Gutenberg-Universität Mainz Methods and compositions for treatment of autoimmune conditions

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Also Published As

Publication number Publication date
JPH10507361A (ja) 1998-07-21
EP0788546B1 (en) 2006-11-29
ES2276396T3 (es) 2007-06-16
PL319782A1 (en) 1997-08-18
AU711405B2 (en) 1999-10-14
DE69535317T2 (de) 2007-06-21
US6090916A (en) 2000-07-18
EP0788546B9 (en) 2007-06-13
US6534629B1 (en) 2003-03-18
US6040441A (en) 2000-03-21
US6087487A (en) 2000-07-11
DK0788546T3 (da) 2007-04-10
US6121435A (en) 2000-09-19
US20060246547A1 (en) 2006-11-02
WO1996012021A3 (en) 1996-07-25
EP0788546A1 (en) 1997-08-13
ATE346928T1 (de) 2006-12-15
US20100240584A1 (en) 2010-09-23
EP1772516A1 (en) 2007-04-11
JP2006117675A (ja) 2006-05-11
JP3811186B2 (ja) 2006-08-16
PL183855B1 (pl) 2002-07-31
US6046318A (en) 2000-04-04
DE69535317D1 (de) 2007-01-11
HUT77431A (hu) 1998-04-28
US20050191724A1 (en) 2005-09-01
HU225126B1 (en) 2006-06-28
JP2007145851A (ja) 2007-06-14
WO1996012021A2 (en) 1996-04-25
AU4130796A (en) 1996-05-06
JP4101833B2 (ja) 2008-06-18
US6096877A (en) 2000-08-01
US6872808B1 (en) 2005-03-29

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