NZ221681A - 7-oxo-2,3-dihydro-7h-pyrido(3,2,1-ij)-1,3,4-benzoxadiazine-6-carboxylic acid derivatives and pharmaceutical compositions thereof - Google Patents

7-oxo-2,3-dihydro-7h-pyrido(3,2,1-ij)-1,3,4-benzoxadiazine-6-carboxylic acid derivatives and pharmaceutical compositions thereof

Info

Publication number
NZ221681A
NZ221681A NZ221681A NZ22168187A NZ221681A NZ 221681 A NZ221681 A NZ 221681A NZ 221681 A NZ221681 A NZ 221681A NZ 22168187 A NZ22168187 A NZ 22168187A NZ 221681 A NZ221681 A NZ 221681A
Authority
NZ
New Zealand
Prior art keywords
compound
oxo
salt
dihydro
benzoxadiazine
Prior art date
Application number
NZ221681A
Other languages
English (en)
Inventor
Masahiro Aoki
Miyako Kamata
Tatsuo Ohtsuka
Nobuo Shimma
Kazuteru Yokose
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ221681A publication Critical patent/NZ221681A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ221681A 1986-09-12 1987-09-04 7-oxo-2,3-dihydro-7h-pyrido(3,2,1-ij)-1,3,4-benzoxadiazine-6-carboxylic acid derivatives and pharmaceutical compositions thereof NZ221681A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP86112619 1986-09-12

Publications (1)

Publication Number Publication Date
NZ221681A true NZ221681A (en) 1990-12-21

Family

ID=8195410

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ221681A NZ221681A (en) 1986-09-12 1987-09-04 7-oxo-2,3-dihydro-7h-pyrido(3,2,1-ij)-1,3,4-benzoxadiazine-6-carboxylic acid derivatives and pharmaceutical compositions thereof

Country Status (22)

Country Link
JP (3) JPH0696578B2 (ja)
KR (1) KR960002857B1 (ja)
CN (1) CN1017800B (ja)
AT (1) AT389119B (ja)
AU (1) AU602534B2 (ja)
CA (1) CA1336905C (ja)
CZ (1) CZ281195B6 (ja)
DK (1) DK173330B1 (ja)
DZ (1) DZ1124A1 (ja)
FI (1) FI86428C (ja)
HU (1) HU199481B (ja)
IE (1) IE61624B1 (ja)
IL (1) IL83814A (ja)
MC (1) MC1850A1 (ja)
MX (1) MX8302A (ja)
NO (1) NO169125C (ja)
NZ (1) NZ221681A (ja)
PH (1) PH23930A (ja)
PT (1) PT85686B (ja)
SK (1) SK278990B6 (ja)
ZA (1) ZA876636B (ja)
ZW (1) ZW16387A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW16387A1 (en) * 1986-09-12 1988-05-25 Hoffmann La Roche Tricyclic compounds
EP1757598A4 (en) 2004-05-13 2010-07-21 Daiichi Seiyaku Co SUBSTITUTED PYRROLIDINE DERIVATIVE
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
EP2383271B1 (en) 2006-03-13 2013-07-10 Kyorin Pharmaceutical Co., Ltd. Aminoquinolones as GSK-3 Inhibitors
KR101563018B1 (ko) 2007-09-11 2015-10-23 교린 세이야꾸 가부시키 가이샤 Ｇｓｋ-３ 억제제로서의 시아노아미노퀴놀론 및 테트라졸로아미노퀴놀론
CN102344457B (zh) 2007-09-12 2015-07-22 杏林制药株式会社 作为 gsk-3 抑制剂的螺环状氨基喹诺酮
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (en) * 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
CA2755120C (en) 2009-03-11 2017-05-16 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as gsk-3 inhibitors
CN107522718B (zh) * 2017-09-14 2019-11-08 浙江国邦药业有限公司 一种马波沙星的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW16387A1 (en) * 1986-09-12 1988-05-25 Hoffmann La Roche Tricyclic compounds

Also Published As

Publication number Publication date
CN1017800B (zh) 1992-08-12
AU7811487A (en) 1988-03-17
CZ281195B6 (cs) 1996-07-17
DZ1124A1 (fr) 2004-09-13
CZ660487A3 (en) 1996-04-17
JPH0826030B2 (ja) 1996-03-13
NO169125B (no) 1992-02-03
JPH0819120B2 (ja) 1996-02-28
CA1336905C (en) 1995-09-05
JPH07138256A (ja) 1995-05-30
JPH0696578B2 (ja) 1994-11-30
PH23930A (en) 1990-01-23
KR880003954A (ko) 1988-06-01
ZA876636B (en) 1988-07-27
MC1850A1 (fr) 1988-09-30
IE872444L (en) 1988-03-12
MX8302A (es) 1993-12-01
NO169125C (no) 1992-05-13
HUT47294A (en) 1989-02-28
PT85686A (en) 1987-10-01
DK477287D0 (da) 1987-09-11
JPS63132891A (ja) 1988-06-04
AU602534B2 (en) 1990-10-18
FI86428C (fi) 1992-08-25
FI86428B (fi) 1992-05-15
DK477287A (da) 1988-03-13
FI873940A0 (fi) 1987-09-11
FI873940A (fi) 1988-03-13
KR960002857B1 (ko) 1996-02-27
IL83814A (en) 1991-09-16
IE61624B1 (en) 1994-11-16
PT85686B (pt) 1990-05-31
HU199481B (en) 1990-02-28
DK173330B1 (da) 2000-07-24
ATA263887A (de) 1989-03-15
CN87106838A (zh) 1988-05-11
SK660487A3 (en) 1998-05-06
ZW16387A1 (en) 1988-05-25
JPH07138262A (ja) 1995-05-30
NO873816L (no) 1988-03-14
AT389119B (de) 1989-10-25
NO873816D0 (no) 1987-09-11
SK278990B6 (sk) 1998-05-06

Similar Documents

Publication Publication Date Title
US4801584A (en) Pyrido(3,2,1-IJ)-1,3,4 benzoxadiazine derivatives
US4556658A (en) 7-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acids and antibacterial agents containing these compounds
EP1004582B1 (en) Pyridazino quinoline compounds
US4705788A (en) Novel antibacterial 7-amino-1(substituted cyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
CZ192892A3 (en) Derivatives of 7-azaisoindolinyl-quinolonecarboxylic and naphthyridonecarboxylic acids
IE54898B1 (en) New quinolone compounds and preparation thereof
NZ221681A (en) 7-oxo-2,3-dihydro-7h-pyrido(3,2,1-ij)-1,3,4-benzoxadiazine-6-carboxylic acid derivatives and pharmaceutical compositions thereof
NO862042L (no) Antibakterielt virksomme chinolonkarboksylsyreestere.
IE860062L (en) Naphthyridines and pyridines
US4616019A (en) Naphthyridine antibacterial compounds
US4864023A (en) Pyrido(3,2,1-IJ)-1,3,4-benzoxadiazine derivatives
US4847375A (en) Antibacterial 1,8-bridged 4-quinoline-3-carboxylic acids
US4607032A (en) Quino-benoxazine antibacterial compounds
US4774246A (en) Quinoline antibacterial compounds
US4533663A (en) Quino-benzothiazine antibacterial compounds
IE58390B1 (en) Naphthyridine antibacterial compounds
US4720495A (en) Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection
EP0162333A1 (en) Quino-benzothiazine antibacterial compounds
JPH037674B2 (ja)
FI88041C (fi) Pyrido/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat
Leysen Synthesis and biological evaluation of new quinolones as potential antibacterial agents
NO171162B (no) Pyrido-benzoksadiazinderivater
JPH05279358A (ja) キノロンカルボン酸化合物
CS235545B2 (cs) Způsob přípravy derivátů 1-ethyl nebo vinyl-6-halogen-1,4-dihydro-4- oxo-7-/1 -piperazinyl/-!,8-nafthyridinu

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)