NO991823L - Substituerte tricykliske forbindelser - Google Patents

Substituerte tricykliske forbindelser

Info

Publication number
NO991823L
NO991823L NO991823A NO991823A NO991823L NO 991823 L NO991823 L NO 991823L NO 991823 A NO991823 A NO 991823A NO 991823 A NO991823 A NO 991823A NO 991823 L NO991823 L NO 991823L
Authority
NO
Norway
Prior art keywords
tricyclic compounds
substituted tricyclic
substituted
compounds
tricyclic
Prior art date
Application number
NO991823A
Other languages
English (en)
Norwegian (no)
Other versions
NO991823D0 (no
Inventor
Nicholas James Bach
Jolie Anne Bastian
Douglas Wade Beight
Michael Dean Kinnick
Michael John Martinelli
Edward David Mihelich
John Michael Morin Jr
Daniel Jon Sall
Jason Scott Sawyer
Edward C R Smith
Tulio Suarez
Qiuping Wang
Thomas Michael Wilson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO991823D0 publication Critical patent/NO991823D0/no
Publication of NO991823L publication Critical patent/NO991823L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
NO991823A 1998-04-17 1999-04-16 Substituerte tricykliske forbindelser NO991823L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6216598A 1998-04-17 1998-04-17

Publications (2)

Publication Number Publication Date
NO991823D0 NO991823D0 (no) 1999-04-16
NO991823L true NO991823L (no) 1999-10-18

Family

ID=22040624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991823A NO991823L (no) 1998-04-17 1999-04-16 Substituerte tricykliske forbindelser

Country Status (27)

Country Link
EP (2) EP1156050B1 (ko)
JP (1) JP4435325B2 (ko)
KR (1) KR19990083234A (ko)
CN (1) CN1235968A (ko)
AR (1) AR018185A1 (ko)
AT (2) ATE259818T1 (ko)
AU (1) AU757454B2 (ko)
BR (1) BR9901275A (ko)
CA (1) CA2269256A1 (ko)
CO (1) CO5080728A1 (ko)
CZ (1) CZ137199A3 (ko)
DE (2) DE69914951T2 (ko)
EA (1) EA003129B1 (ko)
ES (2) ES2213668T3 (ko)
HU (1) HUP9901219A1 (ko)
ID (1) ID23219A (ko)
IL (1) IL129484A0 (ko)
NO (1) NO991823L (ko)
NZ (1) NZ335252A (ko)
PE (1) PE20000472A1 (ko)
PL (1) PL332564A1 (ko)
SG (1) SG106035A1 (ko)
SV (1) SV1999000052A (ko)
TR (1) TR199900842A2 (ko)
TW (1) TW555760B (ko)
YU (1) YU19099A (ko)
ZA (1) ZA992773B (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009978A1 (en) * 1997-08-28 1999-03-04 Eli Lilly And Company Method for treatment of non-rheumatoid athritis
WO2001074817A1 (fr) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Derives d'hydrazide
CA2413582A1 (en) * 2000-07-14 2002-01-24 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
DE60120758T2 (de) * 2000-12-18 2007-05-16 Eli Lilly And Co., Indianapolis Tetracyclische derivate als spla2 inhibitoren
US6933313B2 (en) 2001-03-28 2005-08-23 Eli Lilly And Company Substituted carbazoles as inhibitors of sPLA2
JP2005527464A (ja) * 2001-08-09 2005-09-15 イーライ・リリー・アンド・カンパニー ｓＰＬＡ２インヒビターとしてのシクロヘプタＢインドール誘導体
ATE312817T1 (de) 2001-08-09 2005-12-15 Lilly Co Eli Cyclohept'bö indolderivate als spla2-inhibitoren
US6992100B2 (en) 2001-12-06 2006-01-31 Eli Lilly And Company sPLA2 inhibitors
WO2006050007A2 (en) 2004-11-01 2006-05-11 Wyeth Substituted indolizines and derivatives as cns agents
ES2523580T3 (es) 2008-01-11 2014-11-27 Albany Molecular Research, Inc. Piridoindoles substituidos con (1-Azinona)
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
MX338516B (es) * 2011-04-14 2016-04-20 Actelion Pharmaceuticals Ltd Derivados de acido 7- (heteroaril-amino) -6, 7, 8, 9- tetrahidropirido[1,2-a] indol acetico y sus usos como modulador del receptor de prostaglandina.
PL2825541T3 (pl) 2012-03-16 2016-12-30 Modulatory receptora x wątroby
SI2825542T1 (sl) 2012-03-16 2017-01-31 Vitae Pharmaceutical Inc., Modulatorji jetrnega receptorja X

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
US6645976B1 (en) * 1994-07-21 2003-11-11 Eli Lilly And Company Indolizine SPLA2inhibitors
CA2240395A1 (en) * 1995-12-13 1997-06-19 David Kent Herron Naphthyl acetamides as spla2 inhibitors
IL129481A0 (en) * 1996-10-30 2000-02-29 Lilly Co Eli Substituted tricyclics
WO1999016453A1 (en) * 1997-09-26 1999-04-08 Eli Lilly And Company Method for the treatment of cystic fibrosis
JP2001522884A (ja) * 1997-11-14 2001-11-20 イーライ・リリー・アンド・カンパニー アルツハイマー病の処置方法

Also Published As

Publication number Publication date
EP1156050A3 (en) 2001-11-28
CZ137199A3 (cs) 1999-11-17
EP0950661B1 (en) 2003-11-12
ES2213668T3 (es) 2004-09-01
ES2210979T3 (es) 2004-07-01
AU757454B2 (en) 2003-02-20
EA199900304A2 (ru) 1999-10-28
ATE254128T1 (de) 2003-11-15
DE69914951D1 (de) 2004-03-25
DE69914951T2 (de) 2004-12-23
EP1156050A2 (en) 2001-11-21
ID23219A (id) 2000-03-30
NZ335252A (en) 2000-11-24
EP1156050B1 (en) 2004-02-18
BR9901275A (pt) 2000-05-02
JP4435325B2 (ja) 2010-03-17
AU2381899A (en) 1999-10-28
NO991823D0 (no) 1999-04-16
PL332564A1 (en) 1999-10-25
IL129484A0 (en) 2000-02-29
HU9901219D0 (en) 1999-06-28
ZA992773B (en) 2002-07-16
CA2269256A1 (en) 1999-10-17
PE20000472A1 (es) 2000-06-02
TW555760B (en) 2003-10-01
TR199900842A2 (xx) 2000-09-21
DE69912670T2 (de) 2004-08-12
HUP9901219A1 (hu) 2000-08-28
CO5080728A1 (es) 2001-09-25
SG106035A1 (en) 2004-09-30
YU19099A (sh) 2001-09-28
SV1999000052A (es) 2000-03-14
EA199900304A3 (ru) 2000-04-24
JPH11322745A (ja) 1999-11-24
CN1235968A (zh) 1999-11-24
KR19990083234A (ko) 1999-11-25
ATE259818T1 (de) 2004-03-15
EA003129B1 (ru) 2003-02-27
DE69912670D1 (de) 2003-12-18
EP0950661A1 (en) 1999-10-20
AR018185A1 (es) 2001-10-31

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FC2A Withdrawal, rejection or dismissal of laid open patent application